Phagosomal degradation increases TLR access to bacterial ligands and enhances macrophage sensitivity to bacteria

Journal of Immunology

Volumn 187, Issue 11, 2011, Pages 6002-6010

  Wolf, Andrea J ^a   Arruda, Andrea ^a   Reyes, Christopher N ^a   Kaplan, Amber T ^a   Shimada, Takahiro ^b   Shimada, Kenichi ^a   Arditi, Moshe ^a   Liu, George ^a   Underhill, David M ^a,c  

^a CEDARS SINAI MEDICAL CENTER   (United States)

^b KINKI UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CASPASE RECRUITMENT DOMAIN PROTEIN 15; CRYOPYRIN; CYTOCHALASIN D; GAMMA INTERFERON; INTERLEUKIN 6; LYSOZYME; MESSENGER RNA; MYELOID DIFFERENTIATION FACTOR 88; PEPTIDOGLYCAN; TOLL LIKE RECEPTOR 2; TOLL LIKE RECEPTOR 9; TUMOR NECROSIS FACTOR ALPHA; VANCOMYCIN;

ACETYLATION; ANIMAL CELL; ANIMAL EXPERIMENT; ANTIBIOTIC RESISTANCE; ARTICLE; BACTERIAL STRAIN; CELL MATURATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOPLASM; HUMAN; INFLAMMATION; INNATE IMMUNITY; MACROPHAGE; MOUSE; NONHUMAN; PEPTIDE SYNTHESIS; PHAGOCYTE; PHAGOCYTOSIS; PHAGOSOME; PRIORITY JOURNAL; PROTEIN DEGRADATION; SIGNAL TRANSDUCTION; STAPHYLOCOCCUS AUREUS;

ANIMALS; IMMUNITY, INNATE; INFLAMMATION; LIGANDS; MACROPHAGES; MICE; MICE, KNOCKOUT; PHAGOCYTOSIS; PHAGOSOMES; POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; STAPHYLOCOCCAL INFECTIONS; STAPHYLOCOCCUS AUREUS; TOLL-LIKE RECEPTORS;

EID: 82755190050     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1100232     Document Type: Article

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