NADPH oxidase activity controls phagosomal proteolysis in macrophages through modulation of the lumenal redox environment of phagosomes

Proceedings of the National Academy of Sciences of the United States of America

Volumn 107, Issue 23, 2010, Pages 10496-10501

  Rybicka, Joanna M ^a   Balce, Dale R ^a   Khan, Morgan F ^a   Krohn, Regina M ^a   Yates, Robin M ^a  

^a UNIVERSITY OF CALGARY   (Canada)

Author keywords

Antigen processing; Cathepsin; Disulfide reduction; Lysosome; Phagocytosis

Indexed keywords

ASPARTIC ACID; CATHEPSIN; CYSTEINE; DISULFIDE; HYDROLASE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; LYSOSOME; MACROPHAGE; MOUSE; NONHUMAN; OXIDATION REDUCTION REACTION; PH; PHAGOSOME; PRIORITY JOURNAL; PROTEIN DEGRADATION;

ANIMALS; BIOCATALYSIS; CATHEPSINS; HYDROGEN-ION CONCENTRATION; LYSOSOMES; MACROPHAGES; MEMBRANE GLYCOPROTEINS; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; NADPH OXIDASE; NITRIC OXIDE SYNTHASE TYPE II; OXIDATION-REDUCTION; PHAGOSOMES; REACTIVE OXYGEN SPECIES;

EID: 77953782625     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.0914867107     Document Type: Article

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