Synthesis and biological evaluation of novel benzamide derivatives as potent smoothened antagonists

Bioorganic and Medicinal Chemistry Letters

Volumn 24, Issue 5, 2014, Pages 1426-1431

  Wu, Tian Ming ^a   Wang, Dao Cai ^b   Xiang, Pu ^a   Zhang, Jian Nan ^a   Sang, Ya Xiong ^a   Lin, Hong Jun ^a   Chen, Jie ^a   Xie, Gang ^a   Song, Hang ^b   Zhao, Ying Lan ^a   Xie, Yong Mei ^a  

^a SICHUAN UNIVERSITY   (China)

^b SICHUAN UNIVERSITY   (China)

Author keywords

Amide derivatives; Hedgehog; Smoothened antagonist

Indexed keywords

AMIDE DERIVATIVES; HEDGEHOG; SMOOTHENED ANTAGONIST;

ANIMALS; BENZAMIDES; CELL LINE, TUMOR; HEDGEHOG PROTEINS; HEK293 CELLS; HUMANS; RECEPTORS, G-PROTEIN-COUPLED; SIGNAL TRANSDUCTION; STRUCTURE-ACTIVITY RELATIONSHIP; SULFONES; ZEBRAFISH;

EID: 84894541846     PISSN: 0960894X     EISSN: 14643405     Source Type: Journal    
DOI: 10.1016/j.bmcl.2014.01.006     Document Type: Article

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