A KCNQ1 mutation contributes to the concealed type 1 long QT phenotype by limiting the Kv7.1 channel conformational changes associated with protein kinase A phosphorylation

Heart Rhythm

Volumn 11, Issue 3, 2014, Pages 459-468

  Bartos, Daniel C ^a   Giudicessi, John R ^b   Tester, David J ^b   Ackerman, Michael J ^b   Ohno, Seiko ^c   Horie, Minoru ^c   Gollob, Michael H ^d   Burgess, Don E ^a   Delisle, Brian P ^a  

^a UNIVERSITY OF KENTUCKY   (United States)

^b MAYO CLINIC   (United States)

^c SHIGA UNIVERSITY OF MEDICAL SCIENCE   (Japan)

^d UNIVERSITY OF OTTAWA HEART INSTITUTE   (Canada)

Author keywords

IKs; KCNQ1; Kv7.1; Long QT syndrome; PKA activation; Treadmill stress test

Indexed keywords

I(KS); KCNQ1; KV7.1; LONG QT SYNDROME; PKA ACTIVATION; TREADMILL STRESS TEST;

ADULT; CYCLIC AMP-DEPENDENT PROTEIN KINASES; ELECTROCARDIOGRAPHY; EXERCISE TEST; FEMALE; GENOTYPE; HUMANS; KCNQ1 POTASSIUM CHANNEL; MALE; MIDDLE AGED; MUTATION; PEDIGREE; PHENOTYPE; PHOSPHORYLATION; RETROSPECTIVE STUDIES; ROMANO-WARD SYNDROME;

EID: 84894535231     PISSN: 15475271     EISSN: 15563871     Source Type: Journal    
DOI: 10.1016/j.hrthm.2013.11.021     Document Type: Article

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