Genetic influences on adolescent sexual behavior: Why genes matter for environmentally oriented researchers

Psychological Bulletin

Volumn 140, Issue 2, 2014, Pages 434-465

  Harden, K Paige ^a  

^a UNIVERSITY OF TEXAS AT AUSTIN   (United States)

Author keywords

Adolescence; Age at first sex; Behavior genetics; Gene environment correlation; Twins

Indexed keywords

ADOLESCENT; ADOLESCENT BEHAVIOR; ARTICLE; BEHAVIOR GENETICS; GENETICS; GENOTYPE ENVIRONMENT INTERACTION; HUMAN; PERSONALITY; PSYCHOLOGICAL ASPECT; SEXUAL BEHAVIOR; SEXUALITY; TWINS;

ADOLESCENT; ADOLESCENT BEHAVIOR; GENE-ENVIRONMENT INTERACTION; GENETICS, BEHAVIORAL; HUMANS; PERSONALITY; SEXUAL BEHAVIOR; SEXUALITY; TWIN STUDIES AS TOPIC; TWINS;

EID: 84894493535     PISSN: 00332909     EISSN: None     Source Type: Journal    
DOI: 10.1037/a0033564     Document Type: Article

References (266)

1. Abler, B., Seeringer, A., Hartmann, A., Grön, G., Metzger, C., Walter, M., & Stingl, J. (2011). Neural correlates of antidepressant-related sexual dysfunction: A placebo-controlled fMRI study on healthy males under subchronic paroxetine and bupropion. Neuropsychopharmacology, 36, 1837-1847. doi:10.1038/npp.2011.66
2. Adolescent Family Life Act, Pub. L. No. 97-35, 95 Stat. 578 (1981).
3. Anastasi, A. (1958). Heredity, environment, and the question "how?" Psychological Review, 65, 197-208. doi:10.1037/h0044895
4. Anderson-Hunt, M., & Dennerstein, L. (1994). Increased female sexual response after oxytocin. British Medical Journal, 309, 929. doi:10.1136/ bmj.309.6959.929
5. Anderson-Hunt, M., & Dennerstein, L. (1995). Oxytocin and female sexuality. Gynecologic Obstetric Investigation, 40, 217-221. doi:10.1159/ 000292340
6. Argiolas, A., & Melis, M. R. (2004). The role of oxytocin and the paraventricular nucleus in the sexual behavior of male mammals. Physiology & Behavior, 83, 309-317. doi:10.1016/j.physbeh.2004.08.019
7. Argiolas, A., Melis, M. R., Mauri, A., & Gessa, G. L. (1987). Paraventricular nucleus lesion prevents yawning and penile erection induced by apomorphine and oxytocin but not by ACTH in rats. Brain Research, 421, 349-352. doi:10.1016/0006-8993(87)91305-9
8. Arletti, R., & Bertolini, A. (1985). Oxytocin stimulates lordosis behavior in female rats. Neuropeptides, 6, 247-253. doi:10.1016/0143-4179(85)90095-2
9. Baker, L. A., Treloar, S. A., Reynolds, C. A., Heath, A. C., & Martin, N. G. (1996). Genetics of educational attainment in Australian twins: Sexdifferences and secular changes. Behavior Genetics, 26, 89-102. doi: 10.1007/BF02359887
10. Bartels, M., Rietveld, H., Van Baal, G. C. M., & Boomsma, D. I. (2002). Genetic and environmental influences on the development of intelligence. Behavior Genetics, 32, 237-249. doi:10.1023/A:1019772628912
11. Belsky, J., Houts, R. M., & Fearon, R. M. P. (2010). Infant attachment security and the timing of puberty: Testing an evolutionary hypothesis. Psychological Science, 21, 1195-1201. doi:10.1177/0956797610379867
12. Belsky, J., Steinberg, L., & Draper, P. (1991). Childhood experience, interpersonal development, and reproductive strategy: An evolutionary theory of socialization. Child Development, 62, 647-670. doi:10.2307/ 1131166
13. Belsky, J., Steinberg, L., Houts, R. M., Halpern-Felsher, B. L., & the NICHD Early Child Care Research Network. (2010). The development of reproductive strategy in females: Early maternal harshness → earlier menarche → increased sexual risk taking. Developmental Psychology, 46, 120-128. doi:10.1037/a0015549
14. Ben Zion, I. Z., Tessler, R., Cohen, L., Lerer, E., Raz, Y., Bachner-Melman, R.,Ebstein, R. P. (2006). Polymorphisms in the dopamine D4 receptor gene (DRD4) contribute to individual differences in human sexual behavior: Desire, arousal and sexual function. Molecular Psychiatry, 11, 782-786. doi:10.1038/sj.mp.4001832
15. Bhasin, S., Woodhouse, L., Casaburi, R., Singh, A. B., Bhasin, D., Berman, N.,Storer, T. W. (2001). Testosterone dose-response relationships in healthy young men. American Journal of Physiology: Endocrinology and Metabolism, 281, E1172-E1181.
16. Bishop, J. R., Moline, J., Ellingrod, V. L., Schultz, S. K., & Clayton, A. H. (2006). Serotonin 2A -1438 G/A and G-protein Beta3 subunit C825T polymorphisms in patients with depression and SSRI-associated sexual side-effects. Neuropsychopharmacology, 31, 2281-2288. doi:10.1038/sj.npp.1301090
17. Blaicher, W., Gruber, D., Bieglmayer, C., Blaicher, A. M., Knogler, W., & Huber, J. C. (1999). The role of oxytocin in relation to female sexual arousal. Gynecologic Obstetric Investigation, 47, 125-126. doi:10.1159/ 000010075
18. Blakemore, S.-J., Burnett, S., & Dahl, R. E. (2010). The role of puberty in the developing adolescent brain. Human Brain Mapping, 31, 926-933. doi:10.1002/hbm.21052
19. Blank, H. (2007). Virgin: The untouched history. New York, NY: Bloomsbury Publishing.
20. Boonstra, H. (2001, June). The "Add Health" survey: Origins, purposes, and design. Guttmacher Report on Public Policy, 4(3), 10-12.
21. Bouchard, T. J., Jr., Lykken, D. T., McGue, M., Segal, N. L., & Tellegen, A. (1990, October 12). Sources of human psychological differences: The Minnesota Study of Twins Reared Apart. Science, 250, 253-228. doi: 10.1126/science.2218526
22. Bricker, J. B., Stallings, M. C., Corley, R. P., Wadsworth, S. J., Bryan, A., Timberlake, D. S.,DeFries, J. C. (2006). Genetic and environmental influences on age at sexual initiation in the Colorado Adoption Project. Behavior Genetics, 36, 820-832. doi:10.1007/s10519-006-9079-2
23. Buhi, E. R., & Goodson, P. (2007). Predictors of adolescent sexual behavior and intention: A theory-guided systematic review. Journal of Adolescent Health, 40, 4-21. doi:10.1016/j.jadohealth.2006.09.027
24. Bulmer, M. G. (1989). Maintenance of genetic variability by mutationselection balance: A child's guide through the jungle. Genome, 31, 761-767. doi:10.1139/g89-135
25. Bureau of Labor Statistics, U.S. Department of Labor. (2012). National Longitudinal Survey of Youth 1979 cohort, 1979-2010 (Rounds 1-24) [Computer file]. Columbus, OH: Center for Human Resource Research, The Ohio State University.
26. Burger, H., Hailes, J., & Nelson, J. (1987). Effect of combined implants of oestradiol and testosterone on libido in postmenstrual women. British Medical Journal, 294, 936-937. doi:10.1136/bmj.294.6577.936
27. Burt, S. A., Donnellan, M. B., Humbad, M. N., Hicks, B. M., McGue, M., & Iacono, W. G. (2010). Does marriage inhibit antisocial behavior? An examination of selection vs causation via a longitudinal twin design. Archives of General Psychiatry, 67, 1309 -1315. doi:10.1001/ archgenpsychiatry.2010.159
28. Button, T. M. M., Corley, R. P., Rhee, S. H., Hewitt, J. K., Young, S. E., & Stallings, M. C. (2007). The role of conduct disorder in explaining the comorbidity between alcohol and illicit drug dependence in adolescence. Drug and Alcohol Dependence, 87, 46-53. doi:10.1016/j.drugalcdep.2006.07.012
29. Caldwell, J. D., Prange, A. J., Jr., & Pedersen, C. A. (1986). Oxytocin facilitates the sexual receptivity of estrogen-treated female rats. Neuropeptides, 7, 175-189. doi:10.1016/0143-4179(86)90093-4
30. Carmichael, M. S., Humbert, R., Dixen, J., Palmisano, G., Greenleaf, W., & Davidson, J. M. (1987). Plasma oxytocin increases in the human sexual response. Journal of Clinical Endocrinology & Metabolism, 64, 27-31. doi:10.1210/jcem-64-1-27
31. Carter, C. S. (1992). Oxytocin and sexual behavior. Neuroscience and Biobehavioral Reviews, 16, 131-144. doi:10.1016/S0149-7634(05)80176-9
32. Cavanagh, S. E. (2004). The sexual debut of girls in early adolescence: The intersection of race, pubertal timing, and friendship group characteristics. Journal of Research on Adolescence, 14, 285-312. doi:10.1111/j.1532-7795.2004.00076.x
33. Charmantier, A., Perrins, C., McCleery, R. H., & Sheldon, B. C. (2006). Quantitative genetics of age at reproduction in wild swans: Support for antagonistic pleiotropy models of senescence. PNAS: Proceedings of the National Academy of Sciences, USA, 103, 6587-6592. doi:10.1073/pnas.0511123103
34. Charney, E. (2012). Behavior genetics and postgenomics. Behavioral and Brain Sciences, 35, 331-358. doi:10.1017/S0140525X11002226
35. Cherkas, L. F., Oelsner, E. C., Mak, Y. T., Valdes, A., & Spector, T. D. (2004). Genetic influences on female infidelity and number of sexual partners in humans: A linkage and association study of the role of the vasopressin receptor gene (AVPR1A). Twin Research, 7, 649-658. doi:10.1375/1369052042663922
36. Comings, D. E., & Blum, K. (2000). Reward deficiency syndrome: Genetic aspects of behavioral disorders. Progress in Brain Research, 126, 325- 341. doi:10.1016/S0079-6123(00)26022-6
37. Comings, D. E., Muhleman, D., Johnson, J. P., & MacMurray, J. P. (2002). Parent- daughter transmission of the androgen receptor gene as an explanation of the effect of father absence on age of menarche. Child Development, 73, 1046-1051. doi:10.1111/1467-8624.00456
38. Compton, M. T., & Miller, A. H. (2001). Sexual side effects associated with conventional and atypical antipsychotics. Psychopharmacology Bulletin, 35(3), 89-108.
39. Conley, D., & Rauscher, E. (2011). The equal environments assumption in the post-genomic age: Using misclassified twins to estimate bias in heritability models (NBER Working Paper No. 16711). Retrieved from http://www.nber.org/papers/w16711
40. Coyne, C. A., & D'onofrio, B. M. (2012). Some (but not much) progress toward understanding teenage childbearing: A review of research from the past decade. Advances in Child Development and Behavior, 42, 113-152. doi:10.1016/B978-0-12-394388-0.00004-6
41. Coyne, C. A., Långström, N., Rickert, M. E., Lichtenstein, P., & D'onofrio, B. M. (2013). Maternal age at first birth and offspring criminality: Using the children-of-twins design to test causal hypotheses. Development and Psychopathology, 25, 17-35. doi:10.1017/ S0954579412000879
42. Deater-Deckard, K., Fulker, D. W., & Plomin, R. (1999). A genetic study of the family environment in the transition to early adolescence. Journal of Child Psychology and Psychiatry, 40, 769-775. doi:10.1111/1469-7610.00492
43. Dick, D. M. (2011). Gene-environment interaction in psychological traits and disorders. Annual Review of Clinical Psychology, 7, 383-409. doi:10.1146/annurev-clinpsy-032210-104518
44. Dick, D. M., Wang, J. C., Plunkett, J., Allev, F., Hinrichs, A., Bertelsen, S.,Goate, A. (2007). Family-based association analyses of alcohol dependence phenotypes across DRD2 and neighboring gene ANKK1. Alcoholism: Clinical and Experimental Research, 31, 1645-1653. doi: 10.1111/j.1530-0277.2007.00470.x
45. Ding, Y.-C., Chi, H.-C., Grady, D. L., Morishima, A., Kidd, J. R., Kidd, K. K.,Moyzis, R. K. (2002). Evidence of positive selection acting at the human dopamine receptor D4 gene locus. PNAS: Proceedings of the National Academy of Sciences, USA, 99, 309-314. doi:10.1073/pnas.012464099
46. Dominguez, J. M., & Hull, E. M. (2005). Dopamine, the medial preoptic area, and male sexual behavior. Physiology & Behavior, 86, 356-368. doi:10.1016/j.physbeh.2005.08.006
47. Donahue, K. L., D'onofrio, B. M., Lichtenstein, P., & Långström, N. (2013). Testing putative causal associations of risk factors for early intercourse in the Study of Twin Adults: Genes and Environment (STAGE). Archives of Sexual Behavior, 42, 35-44. doi:10.1007/s10508-012-9947-1
48. Donahue, K. L., Lichtenstein, P., Långström, N., & D'onofrio, B. M. (2013). Why does early sexual intercourse predict subsequent maladjustment? Exploring potential familial confounds. Health Psychology, 32, 180-189. doi:10.1037/a0028922
49. Donahue, K. L., Lichtenstein, P., Lundström, S., Anckarsäter, H., Hellner Gumpert, C., Långström, N., & D'Onofrio, B. M. (2013). Childhood behavior problems and adolescent sexual risk behavior: Familial confounding in the Child and Adolescent Twin Study in Sweden (CATSS). Journal of Adolescent Health, 52, 606-612. doi:10.1016/j.jadohealth.2012.11.001
50. D'onofrio, B. M., Goodnight, J. A., Van Hulle, C. A., Rodgers, J. L., Rathouz, P. J., Waldman, I. D., & Lahey, B. B. (2009). Maternal age at childbirth and offspring disruptive behaviors: Testing the causal hypothesis. Journal of Child Psychology and Psychiatry, 50, 1018-1028. doi:10.1111/j.1469-7610.2009.02068.x
51. D'onofrio, B. M., Turkheimer, E., Emery, R. E., Slutske, W. S., Heath, A. C., Madden, P. A. F., & Martin, N. G. (2006). A genetically informed study of the processes underlying the association between parental marital instability and offspring adjustment. Developmental Psychology, 42, 486-499. doi:10.1037/0012-1649.42.3.486
52. Donohew, L., Zimmerman, R., Cupp, P. S., Novak, S., Colon, S., & Abell, R. (2000). Sensation seeking, impulsive decision-making, and risky sex: Implications for risk-taking and design of interventions. Personality and Individual Differences, 28, 1079 -1091. doi:10.1016/S0191-8869(99)00158-0
53. Dunne, M. P., Martin, N. G., Slutske, W. S., Dinwiddie, S. H., Bucholz, K. K., Madden, P. A. F., & Heath, A. C. (1997). Genetic and environmental contributions to variance in age at first sexual intercourse. Psychological Science, 8, 211-216. doi:10.1111/j.1467-9280.1997.tb00414.x
54. East, P. L., & Jacobson, L. J. (2001). The younger siblings of teenage mothers: A follow-up of their pregnancy risk. Developmental Psychology, 37, 254-264. doi:10.1037/0012-1649.37.2.254
55. Eisenberg, D. T. A., Campbell, B., MacKillop, J., Modi, M., Dang, D., Lum, J. K., & Wilson, D. S. (2007).Polymorphisms in the dopamine D4 and D2 receptor genes and reproductive and sexual behaviors. Evolutionary Psychology, 5, 696-715. doi:10.1186/1744-9081-3-2
56. Elks, C. E., Perry, J. R., Sulem, P., Chasman, D. I., Franceschini, N., He, C.,Murray, A. (2010). Thirty new loci for age at menarche identified by a meta-analysis of genome-wide association studies. Nature Genetics, 42, 1077-1085.
57. Ellis, B. J. (2004). Timing of pubertal maturation in girls: An integrated life history approach. Psychological Bulletin, 130, 920-958. doi:10.1037/ 0033-2909.130.6.920
58. Fishbein, M. (2000). The role of theory in HIV prevention. AIDS Care, 12, 273-278. doi:10.1080/09540120050042918
59. Fisher, R. A. (1930). The genetical theory of natural selection. Oxford, England: Clarendon Press.
60. Flannery, D. J., Rowe, D. C., & Gulley, B. L. (1993). Impact of pubertal status, timing, and age on adolescent sexual experience and delinquency. Journal of Adolescent Research, 8, 21- 40. doi:10.1177/ 074355489381003
61. Forbes, E. E., & Dahl, R. E. (2010). Pubertal development and behavior: Hormonal activation of social and motivational tendencies. Brain and Cognition, 72, 66-72. doi:10.1016/j.bandc.2009.10.007
62. Freese, J. (2008). Genetics and the social science explanation of individual outcomes. American Journal of Sociology, 114(Suppl. 1), S1-S35. doi: 10.1086/592208
63. Garcia, J. R., MacKillop, J., Aller, E. L., Merriwether, A. M., Wilson, D. S., & Lum, J. K. (2010). Associations between dopamine D4 receptor gene variation with both infidelity and sexual promiscuity. PLoS ONE, 5(11), Article e14162. doi:10.1371/journal.pone.0014162
64. Ge, X., Natsuaki, M. N., Neiderhiser, J. M., & Reiss, D. (2007). Genetic and environmental influences on pubertal timing: Results from two national sibling studies. Journal of Research on Adolescence, 17, 767- 788. doi:10.1111/j.1532-7795.2007.00546.x
65. Geronimus, A. T., Korenman, S., & Hillemeier, M. M. (1994). Does young maternal age adversely affect child development? Evidence from cousin comparisons in the United States. Population and Development Review, 20, 585-609. doi:10.2307/2137602
66. Gillespie, J. H., & Turelli, M. (1989). Genotype-environment interactions and the maintenance of polygenic variation. Genetics, 121, 129-138.
67. Gitlin, M. J. (1994). Psychotropic medications and their effects on sexual function: Diagnosis, biology, and treatment approaches. Journal of Clinical Psychiatry, 55, 406-413.
68. Goldman, D., Oroszi, G., & Ducci, F. (2005). Genetics of addictions: Uncovering the genes. Nature Reviews Genetics, 6, 521-532. doi: 10.1038/nrg1635
69. Gorai, I., Inada, M., Morinaga, H., Uchiyama, Y., Yamauchi, H., Hirahara, F., & Chaki, O. (2007). CYP17 and COMT gene polymorphisms can influence bone directly, or indirectly through their effects on endogenous sex steroids, in postmenopausal Japanese women. Bone, 40, 28-36. doi:10.1016/j. bone.2006.07.017
70. Gottlieb, H. (1992). Individual development and evolution. New York, NY: Oxford University Press.
71. Granger, D. A., Schwartz, E. B., Booth, A., & Arentz, M. (1999). Salivary testosterone determination in studies of child health and development. Hormones and Behavior, 35, 18-27. doi:10.1006/hbeh.1998.1492
72. Guo, G., & Tong, Y. (2006). Age at first sexual intercourse, genes, and social context: Evidence from twins and the dopamine D4 receptor gene. Demography, 43, 747-769. doi:10.1353/dem.2006.0029
73. Guo, G., Tong, Y., & Cai, T. (2008). Gene by social context interactions for number of sexual partners among White male youths: Geneticsinformed sociology. American Journal of Sociology, 114(Suppl. 1), S36-S66. doi:10.1086/592207
74. Guo, G., Tong, Y., Xie, C., & Lange, L. A. (2007). Dopamine transporter, gender, and number of sexual partners among young adults. European Journal of Human Genetics, 15, 279-287. doi:10.1038/sj.ejhg.5201763
75. Guo, Y., Xiong, D.-H., Yang, T.-L., Guo, Y.-F., Recker, R. R., & Deng, H.-W. (2006). Polymorphisms of estrogen-biosynthesis genes CYP17 and CYP19 may influence age at menarche: A genetic association study in Caucasian females. Human Molecular Genetics, 15, 2401-2408. doi:10.1093/hmg/ddl155
76. Haberstick, B. C., Smolen, A., & Hewitt, J. K. (2006). Family-based association test of the 5HTTLPR and aggressive behavior in a generalpopulation sample of children. Biological Psychiatry, 59, 836-843. doi:10.1016/j.biopsych.2005.10.008
77. Hallfors, D. D., Waller, M. W., Bauer, D., Ford, C. A., & Halpern, C. T. (2005). Which comes first in adolescence-sex and drugs or depression? American Journal of Preventive Medicine, 29, 163-170. doi:10.1016/j.amepre.2005.06.002
78. Halpern, C. T. (2006). Integrating hormones and other biological factors into a developmental systems model of adolescent female sexuality. New Directions for Child and Adolescent Development, 2006(112), 9-22. doi:10.1002/cd.159
79. Halpern, C. T., Kaestle, C. E., Guo, G., & Hallfors, D. D. (2007). Geneenvironment contributions to young adult sexual partnering. Archives of Sexual Behavior, 36, 543-554. doi:10.1007/s10508-006-9084-9
80. Halpern, C. T., Udry, J. R., Campbell, B., & Suchindran, C. (1993). Testosterone and pubertal development as predictors of sexual activity: A panel analysis of adolescent males. Psychosomatic Medicine, 55, 436-447.
81. Halpern, C. T., Udry, J. R., & Suchindran, C. (1994). Effects of repeated questionnaire administration in longitudinal studies of adolescent males' sexual behavior. Archives of Sexual Behavior, 23, 41-57. doi:10.1007/ BF01541617
82. Halpern, C. T., Udry, J. R., & Suchindran, C. (1997). Testosterone predicts initiation of coitus in adolescent females. Psychosomatic Medicine, 59, 161-171.
83. Halpern, C. T., Udry, J. R., & Suchindran, C. (1998). Monthly measures of salivary testosterone predict sexual activity in adolescent males. Archives of Sexual Behavior, 27, 445-465. doi:10.1023/A:1018700529128
84. Hamer, D. H. (2000). Genetic influences on human fertility and sexuality: Introductory comments from a biological scientist. In J. L. Rodgers, D. C. Rowe, &W. B. Miller (Eds.), Genetic influences on human fertility and sexuality: Theoretical and empirical contributions from the biological and behavioral sciences (pp. 1-2). Boston, MA: Kluwer. doi: 10.1007/978-1-4615-4467-8_1
85. Hamer, D. H. (2002). Genetics of sexual behavior. In J. Benjamin, R. P. Ebstein, & R. H. Belmaker (Eds.), Molecular genetics and the human personality (pp. 257-272): Washington, DC, American Psychiatric Association.
86. Harden, K. P. (2010). Does religious involvement protect against early drinking? A behavior genetic approach. Journal of Child Psychology and Psychiatry, 51, 763-771. doi:10.1111/j.1469-7610.2010.02247.x
87. Harden, K. P. (2012). True love waits? A sibling comparison study of age at first sexual intercourse and romantic relationships in young adulthood. Psychological Science, 23, 1324 -1336. doi:10.1177/ 0956797612442550
88. Harden, K. P., Hill, J. E., Turkheimer, E., & Emery, R. E. (2008). Gene-environment correlation and interaction in peer effects on adolescent alcohol and tobacco use. Behavior Genetics, 38, 339-347. doi: 10.1007/s10519-008-9202-7
89. Harden, K. P., Lynch, S. K., Turkheimer, E., Emery, R. E., D'onofrio, B. M., Slutske, W. S.,Martin, N. G. (2007). A behavior genetic investigation of adolescent motherhood and offspring mental health problems. Journal of Abnormal Psychology, 116, 667-683. doi:10.1037/ 0021-843X.116.4.667
90. Harden, K. P., & Mendle, J. E. (2011a). Adolescent sexual activity and the development of delinquent behavior: The role of relationship context. Journal of Youth and Adolescence, 40, 825-838. doi:10.1007/s10964-010-9601-y
91. Harden, K. P., & Mendle, J. E. (2011b). Why don't smart teens have sex? A behavioral genetic analysis. Child Development, 82, 1327-1344. doi:10.1111/j.1467-8624.2011.01607.x
92. Harden, K. P., Mendle, J., Hill, J. E., Turkheimer, E., & Emery, R. E. (2008). Rethinking timing of first sex and delinquency. Journal of Youth and Adolescence, 37, 373-385.
93. Harden, K. P., Quinn, P. D., & Tucker-Drob, E. M. (2012). Genetically influenced change in sensation seeking drives the rise of delinquent behavior during adolescence. Developmental Science, 15, 150-163. doi:10.1111/j.1467-7687.2011.01115.x
94. Harden, K. P., Turkheimer, E., & Loehlin, J. C. (2007). Genotype by environment interaction in adolescents' cognitive aptitude. Behavior Genetics, 37, 273-283. doi:10.1007/s10519-006-9113-4
95. Harris, J. A., Vernon, P. A., & Boomsma, D. I. (1998). The heritability of testosterone: A study of Dutch adolescent twins and their parents. Behavior Genetics, 28, 165-171. doi:10.1023/A:1021466929053
96. Harris, K. M. (2009). The National Longitudinal Study of Adolescent Health (Add Health), Waves I & II, 1994-1996; Wave III, 2001-2002; Wave IV, 2007-2009 [Data file and documentation]. Chapel Hill, NC: Carolina Population Center, University of North Carolina at Chapel Hill. doi:10.3886/ICPSR27021.v9
97. Hartl, D. L., & Clark, A. G. (2007). Principles of population genetics (4th ed.) Sunderland, MA: Sinauer.
98. Haydon, A. A.,Herring, A. H., & Halpern, C. T. (2012). The association between patterns of emerging sexual behavior and reproductive health in young adulthood. Perspectives on Sexual and Reproductive Health, 44, 218-227. doi:10.1363/4421812
99. Herman, A. I., Kaiss, K. M., Ma, R., Philbeck, J. W., Hasan, A., Dasti, H., & DePetrillo, P. B. (2005). Serotonin transporter promoter polymorphism and monoamine oxidase type A VNTR allelic variants together influence alcohol binge drinking risk in young women. American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, 133(B), 74-78. doi:10.1002/ajmg.b.30135
100. Hewitt, J. K. (2012). Editorial policy on candidate gene association studies and candidate gene-by-environment interaction studies of complex traits. Behavior Genetics, 42, 1-2. doi:10.1007/s10519-011-9504-z
101. Hirschi, T. (1969). Causes of delinquency. Berkeley: University of California Press.
102. Hoekstra, R. A., Bartels, M., & Boomsma, D. I. (2006). Heritability of testosterone levels in 12-year-old twins and its relation to pubertal development. Twin Research and Human Genetics, 9, 558-565. doi: 10.1375/twin.9.4.558
103. Hopper, J. L., Foley, D. L., White, P. A., & Pollaers, V. (2013). Australian Twin Registry: 30 years of progress. Twin Research and Human Genetics, 16, 34-42. doi:10.1017/thg.2012.121
104. Hughes, K. A., & Burleson, M. H. (2000). Evolutionary causes of genetic variation in fertility and other fitness components. In J. L. Rodgers, D. C. Rowe, & W. B. Miller (Eds.), Genetic influences on human fertility and sexuality: Theoretical and empirical contributions from the biological and behavioral sciences (pp. 7-33). Boston, MA: Kluwer. doi:10.1007/ 978-1-4615-4467-8_3
105. Huibregtse, B. M., Bornovalova, M. A., Hicks, B. M., McGue, M., & Iacono, W. (2011). Testing the role of adolescent sexual initiation in later-life sexual risk behavior: A longitudinal twin design. Psychological Science, 22, 924-933. doi:10.1177/0956797611410982
106. Hull, E. M. (2011). Sex, drugs and gluttony: How the brain controls motivated behaviors. Physiology & Behavior, 104, 173-177. doi: 10.1016/j.physbeh.2011.04.057
107. Hull, E. M., & Dominguez, J. M. (2006). Getting his act together: Roles of glutamate, nitric oxide, and dopamine in the medial preoptic area. Brain Research, 1126, 66-75. doi:10.1016/j.brainres.2006.08.031
108. Hull, E. M., Du, J., Lorrain, D. S., & Matuszewich, L. (1997). Testosterone, preoptic dopamine, and copulation in male rats. Brain Research Bulletin, 44, 327-333. doi:10.1016/S0361-9230(97)00211-6
109. Hull, E. M., Muschamp, J. W., & Sato, S. (2004). Dopamine and serotonin: Influences on male sexual behavior. Physiology & Behavior, 83, 291- 307. doi:10.1016/j.physbeh.2004.08.018
110. Hunt, C. B., & Rowe, D. C. (2003). Genetic and shared environmental influences on adolescents' timing of first sexual intercourse: The mod-erating effect of time spent with a sibling. In J. L. Rodgers & H.-P. Kohler (Eds.), The biodemography of human reproduction and fertility (pp. 161-185). Boston, MA: Kluwer. doi:10.1007/978-1-4615-1137-3_8
111. Hur, Y.-M., McGue, M., & Iacono, W. G. (1996). Genetic and shared environmental influences on leisure-time interests in male adolescents. Personality and Individual Differences, 21, 791-801. doi:10.1016/0191-8869(96)00106-7
112. Insel, T. R., & Shapiro, L. E. (1992). Oxytocin receptor distribution reflects social organization in monogamous and polygamous voles. PNAS: Proceedings of the National Academy of Sciences, USA, 89, 5981-5985. doi:10.1073/pnas.89.13.5981
113. Insel, T. R., Wang, Z. X., & Ferris, C. F. (1994). Patterns of brain vasopressin receptor distribution associated with social organization in microtine rodents. Journal of Neuroscience, 14, 5381-5392.
114. Jacobson, K. C., & Rowe, D. C. (1999). Genetic and environmental influences on the relationships between family connectedness, school connectedness, and adolescent depressed mood: Sex differences. Developmental Psychology, 35, 926-939. doi:10.1037/0012-1649.35.4.926
115. Jang, K. L., Vernon, P. A., Livesley, W. J., Stein, M. B., & Wolf, H. (2001). Intra- and extra-familial influences on alcohol and drug misuse: A twin study of gene- environment correlation. Addiction, 96, 1307- 1318. doi:10.1046/j.1360-0443.2001.969130710.x
116. Jenkins, R. B., & Groh, R. H. (1970). Mental symptoms in parkinsonian patients treated with L-dopa. Lancet, 296, 177-180. doi:10.1016/S0140-6736(70)92535-3
117. Jessor, S. L., & Jessor, R. (1975). Transition from virginity to nonvirginity among youth: A social-psychological study over time. Developmental Psychology, 11, 473-484. doi:10.1037/h0076664
118. Jockin, V., McGue, M., & Lykken, D. T. (1996). Personality and divorce: A genetic analysis. Journal of Personality and Social Psychology, 71, 288-299. doi:10.1037/0022-3514.71.2.288
119. Johnson, W., McGue, M., Krueger, R. F., & Bouchard, J. (2004). Marriage and personality: A genetic analysis. Journal of Personality and Social Psychology, 86, 285-294. doi:10.1037/0022-3514.86.2.285
120. Johnson, W., Turkheimer, E., Gottesman, I. I., & Bouchard, T. J. (2009). Beyond heritability twin studies in behavioral research. Current Directions in Psychological Science, 18, 217-220. doi:10.1111/j.1467-8721.2009.01639.x
121. Kadlubar, F. F., Berkowitz, G. S., Delongchamp, R. R., Wang, C., Green, B. L., Tang, G.,Wolff, M. S. (2003). The CYP3A4_1B variant is related to the onset of puberty, a known risk factor for the development of breast cancer. Cancer Epidemiology, Biomarkers & Prevention, 12, 327-331.
122. Kaltiala-Heino, R., Kosunen, E., & Rimpelä, M. (2003). Pubertal timing, sexual behavior and self-reported depression in middle adolescence. Journal of Adolescence, 26, 531-545. doi:10.1016/S0140-1971(03)00053-8
123. Kaprio, J. (2013). The Finnish Twin Cohort Study: An update. Twin Research and Human Genetics, 16, 157-162. doi:10.1017/thg.2012.142
124. Karg, K., Burmeister, M., Shedden, K., & Sen, S. (2011). The serotonin transporter promoter variant (5-HTTLPR), stress, and depression metaanalysis revisited: Evidence of genetic moderation. Archives of General Psychiatry, 68, 444-454. doi:10.1001/archgenpsychiatry.2010.189
125. Kendler, K. S. (1996). Parenting: A genetic-epidemiologic perspective. American Journal of Psychiatry, 153, 11-20.
126. Kendler, K. S., & Baker, J. H. (2007). Genetic influences on measures of the environment: A systematic review. Psychological Medicine, 37, 615-626. doi:10.1017/S0033291706009524
127. Kendler, K. S., Jacobson, K. C., Gardner, C. O., Gillespie, N., Aggen, S. A., & Prescott, C. A. (2007). Creating a social world: A developmental twin study of peer-group deviance. Archives of General Psychiatry, 64, 958-965. doi:10.1001/archpsyc.64.8.958
128. Kendler, K. S., Neale, M. C., Kessler, R. C., Heath, A. C., & Eaves, L. J. (1993). A test of the equal-environment assumption in twin studies ofpsychiatric illness. Behavior Genetics, 23, 21-27. doi:10.1007/ BF01067551
129. Kim, K., & Smith, P. K. (1998). Childhood stress, behavioural symptoms and mother- daughter pubertal development. Journal of Adolescence, 21, 231-240. doi:10.1006/jado.1998.0149
130. Kirby, D. (2002). Antecedents of adolescent initiation of sex, contraceptive use, and pregnancy. American Journal of Health Behavior, 26, 473-485. doi:10.5993/AJHB.26.6.8
131. Kirk, K. M., Blomberg, S. P., Duffy, D. L., Heath, A. C., Owens, I. P., & Martin, N. G. (2001). Natural selection and quantitative genetics of life-history traits in Western women: A twin study. Evolution, 55, 423-435.
132. Klump, K. L., & Culbert, K. M. (2007). Molecular genetic studies of eating disorder: Current status and future directions. Current Directions in Psychological Science, 16, 37- 41. doi:10.1111/j.1467-8721.2007.00471.x
133. Koenig, L. B., McGue, M., Krueger, R. F., & Bouchard, T. J. (2005). Genetic and environmental influences on religiousness: Findings for retrospective and current religiousness ratings. Journal of Personality, 73, 471-488. doi:10.1111/j.1467-6494.2005.00316.x
134. Kogan, S. M., Brody, G. H., Chen, Y., Grange, C. M., Slater, L. M., & DiClemente, R. J. (2010). Risk and protective factors for unprotected intercourse among rural African American young adults. Public Health Reports, 125, 709-717.
135. Kohler, H.-P., Rodgers, J. L., & Christensen, K. (1999). Is fertility behavior in our genes? Findings from a Danish twin study. Population and Development Review, 25, 253-288. doi:10.1111/j.1728-4457.1999.00253.x
136. Kotchick, B. A., Shaffer, A., Miller, K. S., & Forehand, R. (2001). Adolescent sexual risk behavior: A multi-system perspective. Clinical Psychology Review, 21, 493-519. doi:10.1016/S0272-7358(99)00070-7
137. Kuhn, C., Johnson, M., Thomae, A., Lou, B., Simon, S. A., Zhou, G., & Walker, Q. D. (2010). The emergence of gonadal hormone influences on dopaminergic function during puberty. Hormones and Behavior, 58, 122-137. doi:10.1016/j.yhbeh.2009.10.015
138. Lam, T. H., Shi, H. J., Ho, L. M., Stewart, S. M., & Fan, S. (2002). Timing of pubertal maturation and heterosexual behavior among Hong Kong Chinese adolescents. Archives of Sexual Behavior, 31, 359-366. doi: 10.1023/A:1016228427210
139. Landry, D. J., Kaeser, L., & Richards, C. L. (1999). Abstinence promotion and the provision of information about contraception in public school district sexuality education policies. Family Planning Perspectives, 31, 280-286. doi:10.2307/2991538
140. Laub, J. H., Nagin, D. S., & Sampson, R. J. (1998). Trajectories of change in criminal offending: Good marriages and the desistance process. American Sociological Review, 63, 225-238.
141. Laurent, S. M., & Simons, A. D. (2009). Sexual dysfunction in depression and anxiety: Conceptualizing sexual dysfunction as part of an internalizing dimension. Clinical Psychology Review, 29, 573-585. doi: 10.1016/j.cpr.2009.06.007
142. Lesch, K. P., Bengel, D., Heils, A., Zabol, S. Z., Greenberg, B. D., Petri, S.,Murphy, D. L. (1996, November 29). Association of anxietyrelated traits with a polymorphism in the serotonin transporter gene regulatory region. Science, 274, 1527-1531. doi:10.1126/science.274.5292.1527
143. Levine, J. A., Emery, C. R., & Pollack, H. (2007). The well-being of children born to teen mothers. Journal of Marriage and Family, 69, 105-122. doi:10.1111/j.1741-3737.2006.00348.x
144. Lewontin, R. C., Rose, S., & Kamin, L. J. (1984). Not in our genes: Biology, ideology, and human nature. New York, NY: Pantheon Books.
145. Lichtenstein, P., Ganiban, J., Neiderhiser, J. M., Pedersen, N. L., Hansson, K., Cederbald, M.,Reiss, D. (2003). Remembered parental bonding in adult twins: Genetic and environmental influences. Behavior Genetics, 33, 397-408.
146. Lim, M. M., Wang, Z., Olazábal, D. E., Ren, X., Terwilliger, E. F., & Young, L. J. (2004, June 17). Enhanced partner preference in a promiscuous species by manipulating the expression of a single gene. Nature, 429, 754-757. doi:10.1038/nature02539
147. Lim, M. M., & Young, L. J. (2004). Vasopressin-dependent neural circuits underlying pair bond formation in the monogamous prairie vole. Neuroscience, 125, 35-45. doi:10.1016/j.neuroscience.2003.12.008
148. Liu, Y., Curtis, T. J., & Wang, Z. (2001). Vasopressin in the lateral septum regulates pair bond formation in male prairie voles (Microtus ochrogaster). Behavioral Neuroscience, 115, 910-919. doi:10.1037/0735-7044.115.4.910
149. Liu, Y., & Wang, X. Y. (2003). Nucleus accumbens oxytocin and dopamine interact to regulate pair bond formation in female prairie voles. Neuroscience, 121, 537-544. doi:10.1016/S0306-4522(03)00555-4
150. López Turley, R. N. (2003). Are children of young mothers disadvantaged because of their mother's age or family background? Child Development, 74, 465-474. doi:10.1111/1467-8624.7402010
151. Lucht, M. J., Barnow, S., Sonnenfeld, C., Rosenberger, A., Grabe, H. J., Schroeder, W.,Rosskopf, D. (2009). Associations between the oxytocin receptor gene (OXTR) and affect, loneliness and intelligence in normal subjects. Progress in Neuro-Psychopharmacology and Biological Psychiatry, 33, 860-866. doi:10.1016/j.pnpbp.2009.04.004
152. Lyons, M. J., Koenen, K. C., Buchting, F., Meyer, J. M., Eaves, L., Toomey, R.,Tsuang, M. T. (2004). A twin study of sexual behavior in men. Archives of Sexual Behavior, 33, 129-136. doi:10.1023/B: ASEB.0000014327.11433.66
153. Maldonado, R., Saiardi, A., Valverde, O., Samad, T. A., Roques, B. P., & Borrelli, E. (1997, August 7). Absence of opiate rewarding effects in mice lacking dopamine D2 receptors. Nature, 388, 586-589. doi: 10.1038/41567
154. Manolio, T. A., Collins, F. S., Cox, N. J., Goldstein, D. B., Hindorff, L. A., Hunter, D. J.,Visscher, P. M. (2009). Finding the missing heritability of complex diseases. Nature, 461, 747-753. doi:10.1038/nature08494
155. Marston, C., & King, E. (2006). Factors that shape young people's sexual behavior: A systematic review. Lancet, 368, 1581-1586. doi:10.1016/ S0140-6736(06)69662-1
156. Martin, N. G., Eaves, L. J., & Eysenck, H. J. (1977). Genetical, environmental, and personality factors influencing the age of first sexual intercourse in twins. Journal of Biosocial Science, 9, 91-97. doi:10.1017/ S0021932000000493
157. McDonald, J. F., & Ayala, F. J. (1974, August 16). Genetic response to environmental heterogeneity. Nature, 250, 572-574. doi:10.1038/ 250572a0
158. McHale, S. M., Bissell, J., & Kim, J. Y. (2009). Sibling relationship, family, and genetic factors in sibling similarity in sexual risk. Journal of Family Psychology, 23, 562-572. doi:10.1037/a0014982
159. McHugh, R. K., Hoffman, S. G., Asnaani, A., Sawyer, A. T., & Otto, M. W. (2010). The serotonin transporter gene and risk for alcohol dependence: A meta-analytic review. Drug and Alcohol Dependence, 108, 1-6. doi:10.1016/j.drugalcdep.2009.11.017
160. Meade, C. S., Kershaw, T. S., & Ickovics, J. R. (2008). The intergenerational cycle of teenage motherhood: An ecological approach. Health Psychology, 27, 419-429. doi:10.1037/0278-6133.27.4.419
161. Mealey, L., & Segal, N. L. (1993). Heritable and environmental variables affect reproduction-related behaviors, but not ultimate reproductive success. Personality and Individual Differences, 14, 783-794. doi:10.1016/ 0191-8869(93)90091-G
162. Melis, M. R., & Argiolas, A. (1995). Dopamine and sexual behavior. Neuroscience and Biobehavioral Reviews, 19, 19-38. doi:10.1016/ 0149-7634(94)00020-2
163. Mendle, J., & Ferrero, J. (2012). Detrimental psychological outcomes associated with pubertal timing in adolescent boys. Developmental Review, 32, 49-66.
164. Mendle, J., Ferrero, J., Moore, S., & Harden, K. P. (2013). Depression and adolescent sexual activity in romantic and nonromantic relational contexts: A genetically-informative sibling comparison. Journal of Abnormal Psychology, 122, 51-63. doi:10.1037/a0029816
165. Mendle, J., Harden, K. P., Brooks-Gunn, J., & Graber, J. A. (2010). Development's tortoise and hare: Pubertal timing, pubertal tempo, and depressive symptoms in boys and girls. Developmental Psychology, 46, 1341-1353. doi:10.1037/a0020205
166. Mendle, J., Harden, K. P., Turkheimer, E., van Hulle, C. A., D'onofrio, B. M., Brooks-Gunn, J.,Lahey, B. B. (2009). Associations between father absence and age of first sexual intercourse. Child Development, 80, 1463-1480. doi:10.1111/j.1467-8624.2009.01345.x
167. Mendle, J., Turkheimer, E., & Emery, R. E. (2007). Detrimental psychological outcomes associated with early pubertal timing in adolescent girls. Developmental Review, 27, 151-171. doi:10.1016/j.dr.2006.11.001
168. Merilä, J., & Sheldon, B. C. (1999). Genetic architecture of fitness and nonfitness traits: Empirical patterns and development of ideas. Heredity, 83, 103-109.
169. Meston, C. M., & Buss, D. M. (2007). Why humans have sex. Archives of Sexual Behavior, 36, 477-507. doi:10.1007/s10508-007-9175-2
170. Miller, B. C., Norton, M. C., Fan, X., & Christopherson, C. R. (1998). Pubertal development, parental communication, and sexual values in relation to adolescent sexual behaviors. Journal of Early Adolescence, 18, 27-52. doi:10.1177/0272431698018001002
171. Miller, W. B., Pasta, D. J., MacMurray, J., Chiu, C., Wu, H., & Comings, D. E. (1999). Dopamine receptor genes are associated with age at first sexual intercourse. Journal of Biosocial Science, 31, 43-54. doi: 10.1017/S0021932099000437
172. Miller, W. B., Pasta, D. J., MacMurray, J., Muhleman, D., & Comings, D. E. (2000). Genetic influences on childbearing motivation: Further testing a theoretical framework. In J. L. Rodgers, D. C. Rowe, & W. B. Miller (Eds.), Genetic influences on human fertility and sexuality: Theoretical and empirical contributions from the biological and behavioral sciences (pp. 35-66). Boston, MA: Kluwer. doi:10.1007/978-1-4615-4467-8_4
173. Moffitt, T. E. (2005). The new look of behavioral genetics in developmental psychopathology: Gene-environment interplay in antisocial behaviors. Psychological Bulletin, 131, 533-554. doi:10.1037/0033-2909.131.4.533
174. Moffitt, T. E., Caspi, A., & Rutter, M. (2005). Strategy for investigating interactions between measured genes and measured environments. Archives of General Psychiatry, 62, 473-481. doi:10.1001/archpsyc.62.5.473
175. Munafò, M. R., Durrant, C., Lewis, G., & Flint, J. (2009). Gene _ Environment interactions at the serotonin transporter locus. Biological Psychiatry, 65, 211-219. doi:10.1016/j.biopsych.2008.06.009
176. Mustanski, B. S., Viken, R. J., Kaprio, J., Pulkkinen, L., & Rose, R. J. (2004). Genetic and environmental influences on pubertal development: Longitudinal data from Finnish twins at ages 11 and 14. Developmental Psychology, 40, 1188-1198. doi:10.1037/0012-1649.40.6.1188
177. Mustanski, B., Viken, R. J., Kaprio, J., Winter, T., & Rose, R. J. (2007). Sexual behavior in young adulthood: A population-based twin study. Health Psychology, 26, 610-617. doi:10.1037/0278-6133.26.5.610
178. National Institutes of Health revitalization amendments. (1992). Congressional Record, 102, S4708-S4759.
179. Neale, M. C., & Maes, H. H. (2007). Methodology for genetic studies of twins and families. Dordrecht, the Netherlands: Kluwer Academic.
180. Neiderhiser, J. M., Reiss, D., Pedersen, N. L., Lichtenstein, P., Spotts, E. L., Kjell, H.,Olle, E. (2004). Genetic and environmental influences on mothering of adolescents: A comparison of two samples. Developmental Psychology, 40, 335-351.
181. Neiss, M., Rowe, D. C., & Rodgers, J. L. (2002). Does education mediate the relationship between IQ and age of first birth? A behavioural genetic analysis. Journal of Biosocial Science, 34, 259-275. doi:10.1017/ S0021932002002596
182. Nemoda, Z., Szekely, A., & Sasvari-Szekely, M. (2011). Psychopathological aspects of dopaminergic gene polymorphisms in adolescence and young adulthood. Neuroscience and Biobehavioral Reviews, 35, 1665- 1686. doi:10.1016/j.neubiorev.2011.04.002
183. Newcomer, S. F., & Udry, J. R. (1984). Mothers' influence on the sexual behavior of their teenage children. Journal of Marriage and the Family, 46, 477-485. doi:10.2307/352480
184. Pam, A., Kemker, S. S., Ross, C. A., & Golden, R. (1996). The "equal environments assumption" in MZ-DZ twin comparisons: An untenable premise of psychiatric genetics? Acta Geneticae Medicae et Gemellologiae, 45, 349-360.
185. Pasta, D. J., & Miller, W. B. (2000). A heritability study of childbearing motivation. In J. L. Rodgers, D. C. Rowe, &W. B. Miller (Eds.), Genetic influences on human fertility and sexuality: Theoretical and empirical contributions from the biological and behavioral sciences (pp. 107- 120). Boston, MA: Kluwer. doi:10.1007/978-1-4615-4467-8_7
186. Personal Responsibility and Work Opportunity Reconciliation Act, Pub. L. No. 104-93, 110 Stat. 2105 (1996).
187. Plomin, R. (1994). Genetics and experience: The interplay between nature and nurture. Thousand Oaks, CA: Sage.
188. Plomin, R., Corley, R., Defries, J. C., & Fulker, D. W. (1990). Individual differences in television viewing in early childhood: Nature as well as nurture. Psychological Science, 1, 371-377. doi:10.1111/j.1467-9280.1990.tb00244.x
189. Plomin, R., & Defries, J. C. (1983). The Colorado Adoption Project. Child Development, 54, 276-289.
190. Plomin, R., Reiss, D., Hetherington, E. M., & Howe, G. W. (1994). Nature and nurture: Genetic contributions to measures of the family environment. Developmental Psychology, 30, 32-43. doi:10.1037/0012-1649.30.1.32
191. Popma, A., Vermeiren, R., Geluk, C. A. M. L., Rinne, T., van den Brink, W., Knol, D. L.,Doreleijers, T. A. H. (2007). Cortisol moderates the relationship between testosterone and aggression in delinquent male adolescents. Biological Psychiatry, 61, 405-411. doi:10.1016/j.biopsych.2006.06.006
192. Prichard, Z. M., Mackinnon, A. J., Jorm, A. F., & Easteal, S. (2007). AVPR1A and OXTR polymorphisms are associated with sexual and reproductive behavioral phenotypes in humans. Human Mutation, 28, 1150-1156.
193. Public Health Service Act, Pub. L. No. 78-410, 58 Stat. 682 (1944).
194. Richardson, K., & Norgate, S. (2005). The equal environments assumption of classical twin studies may not hold. British Journal of Educational Psychology, 75, 339-350. doi:10.1348/000709904X24690
195. Risch, N., Herrell, R., Lehner, T., Liang, K.-Y., Eaves, L., Hoh, J.,Merikangas, K. R. (2009). Interaction between the serotonin transporter gene (5-HTTLPR), stressful life events, and risk of depression: A meta-analysis. JAMA, 301, 2462-2471. doi:10.1001/jama.2009.878
196. Rodgers, J. L. (1996). Sexual transitions in adolescence. In J. A. Graber, J. Brooks-Gunn, & A. C. Petersen (Eds.), Transitions through adolescence: Interpersonal domains and context (pp. 85-110). Mahwah, NJ: Erlbaum.
197. Rodgers, J. L., Bard, D. E., Johnson, A., D'onofrio, B., & Miller, W. B. (2008). The cross-generational mother- daughter-aunt-niece design: Establishing validity of the MDAN design with NLSY fertility variables. Behavior Genetics, 38, 567-578. doi:10.1007/s10519-008-9225-0
198. Rodgers, J. L., Bard, D. E., & Miller, W. B. (2007). Multivariate Cholesky models of human female fertility patterns in the NLSY. Behavior Genetics, 37, 345-361.
199. Rodgers, J. L., & Kohler, H.-P. (Eds.). (2003). The biodemography of human reproduction and fertility. Boston, MA: Kluwer. doi:10.1007/ 978-1-4615-1137-3
200. Rodgers, J. L., Kohler, H.-P., & Christensen, K. (2003). Genetic variance in human fertility: Biology, psychology, or both? In J. L. Rodgers & H.-P. Kohler (Eds.), The biodemography of human reproduction and fertility (pp. 229-250). Boston, MA: Kluwer. doi:10.1007/978-1-4615-1137-3_12
201. Rodgers, J. L., Kohler, H.-P., Kyvik, K. O., & Christensen, K. (2001). Behavior genetic modeling of human fertility: Findings from a contemporary Danish twin study. Demography, 38, 29-42. doi:10.1353/dem.2001.0009
202. Rodgers, J. L., Kohler, H.-P., McGue, M., Behrman, J. R., Petersen, I., Bingley, P., & Christensen, K. (2008). Education and cognitive ability as direct, mediating, or spurious influences on female age at first birth: Behavior genetic models fit to Danish twin data. American Journal of Sociology, 114(Suppl. 2), S202-S232. doi:10.1086/592205
203. Rodgers, J. L., & Rowe, D. C. (1990). Adolescent sexual activity and mildly deviant behavior: Sibling and friendship effects. Journal of Family Issues, 11, 274-293. doi:10.1177/019251390011003003
204. Rodgers, J. L., Rowe, D. C., & Buster, M. (1999). Nature, nurture, and first sexual intercourse in the USA: Fitting behavioural genetic models on NLSY kinship data. Journal of Biosocial Science, 31, 29-41. doi: 10.1017/S0021932099000292
205. Rodgers, J. L., Rowe, D. C., & Miller, W. B. (Eds.). (2000). Genetic influences on human fertility and sexuality: Theoretical and empirical contributions from the biological and behavioral sciences. Boston, MA: Kluwer. doi:10.1007/978-1-4615-4467-8
206. Rose, M. R. (1982). Antagonistic pleiotropy, dominance, and genetic variation. Heredity, 48, 63-78. doi:10.1038/hdy.1982.7
207. Rowe, D. C. (1994). The limits of family influence: Genes, experience, and behavior. New York, NY: Guilford Press.
208. Rowe, D. C. (2002). On genetic variation in menarche and age at first sexual intercourse: A critique of the Belsky-Draper hypothesis. Evolution and Human Behavior, 23, 365-372. doi:10.1016/S1090-5138(02)00102-2
209. Rowe, D. C., Vesterdal, W. J., & Rodgers, J. L. (1998). Herrnstein's syllogism: Genetic and shared environmental influences on IQ, education, and income. Intelligence, 26, 405- 423. doi:10.1016/S0160-2896(99)00008-2
210. Rutter, M., Pickles, A., Murray, R., & Eaves, L. (2001). Testing hypotheses on specific causal effects on behavior. Psychological Bulletin, 127, 291-324. doi:10.1037/0033-2909.127.3.291
211. Sakai, J. T., Boardman, J. D., Gelhorn, H. L., Smolen, A., Corley, R. R., Huizinga, D.,Stallings, M. C. (2010). Using trajectory analyses to refine phenotype for genetic association: Conduct problems and the serotonin transporter (5HTTLPR). Psychiatric Genetics, 20, 199-206. doi:10.1097/YPG.0b013e32833a20f1
212. Sampson, R. J., & Laub, J. H. (1990). Crime and deviance over the life course: The salience of adult social bonds. American Sociological Review, 55, 609-627.
213. Scarr, S. (1992). Developmental theories for the 1990s: Development and individual differences. Child Development, 63, 1-19. doi:10.2307/ 1130897
214. Scarr, S., & Carter-Saltzman, L. (1979). Twin method: Defense of a critical assumption. Behavior Genetics, 9, 527-542. doi:10.1007/BF01067349
215. Scarr, S., & Grajek, S. (1982). Similarities and differences among siblings. In M. E. Lamb & B. Sutton-Smith (Eds.), Sibling relationships: Their nature and significance across the lifespan (pp. 357-381). Hillsdale, NJ: Erlbaum.
216. Schinka, J. A., Busch, R. M., & Robichaux-Keene, N. (2004). A metaanalysis of the association between the serotonin transporter gene polymorphism (5-HTTLPR) and trait anxiety. Molecular Psychiatry, 9, 197- 202.
217. Schulz, K. M., Molenda-Figueira, H. A., & Sisk, C. L. (2009). Back to the future: The organizational-activational hypothesis adapted to puberty and adolescence. Hormones and Behavior, 55, 597-604. doi:10.1016/j.yhbeh.2009.03.010
218. Segal, N. L., & Stohs, J. H. (2009). Age at first intercourse in twins reared apart: Genetic influence and life history events. Personality and Individual Differences, 47, 127-132. doi:10.1016/j.paid.2009.02.010
219. Shapiro, S. K. (1973, January). Hypersexual behavior complicating levodopa (l-dopa) therapy. Minnesota Medicine, 56(1), 58-59.
220. Sher, K. J., Dick, D. M., Crabbe, J. C., Hutchison, K. E., O'Malley, S. S., & Heath, A. C. (2010). Review: Consilient research approaches in studying Gene × Environment interactions in alcohol research. Addiction Biology, 15, 200-216. doi:10.1111/j.1369-1600.2009.00189.x
221. Sherwin, B. B. (1988). A comparative analysis of the role of androgen in human male and female sexual behavior: Behavioral specificity, critical thresholds, and sensitivity. Psychobiology, 16, 416-425.
222. Sherwin, B. B., & Gelfand, M. M. (1987). The role of androgen in the maintenance of sexual functioning in oophorectomized women. Psychosomatic Medicine, 49, 397-409.
223. Sherwin, B. B., Gelfand, M. M., & Brender, W. (1985). Androgen enhances sexual motivation in females: A prospective, crossover study of sex steroid administration in the surgical menopause. Psychosomatic Medicine, 47, 339-351.
224. Silventoinen, K., Kaprio, J., & Lahelma, E. (2000). Genetic and environmental contributions to the association between body height and educational attainment: A study of adult Finnish twins. Behavior Genetics, 30, 477-485. doi:10.1023/A:1010202902159
225. Simpson, J. A., & Gangestad, S. W. (1991). Individual differences in sociosexuality: Evidence for convergent and discriminant validity. Journal of Personality and Social Psychology, 60, 870-883. doi:10.1037/ 0022-3514.60.6.870
226. Sipsma, H., Biello, K. B., Cole-Lewis, H., & Kershaw, T. (2010). Like father, like son: The intergenerational cycle of adolescent fatherhood. American Journal of Public Health, 100, 517-524. doi:10.2105/AJPH.2009.177600
227. Sisk, C. L., & Foster, D. L. (2004). The neural basis of puberty and adolescence. Nature Neuroscience, 7, 1040-1047. doi:10.1038/nn1326
228. Skytthe, A., Christiansen, L., Kyvik, K. O., Bødker, F. L., Hvidberg, L., Petersen, I.,Christensen, K. (2012). The Danish Twin Registry: Linking surveys, national registers, and biological information. Twin Research and Human Genetics, 1, 104-111. doi:10.1017/thg.2012.77
229. Snyder, P. J., Peachey, H., Berlin, J. A., Hannoush, P., Haddad, G., Dlewati, A.,Strom, B. L. (2000). Effects of testosterone replacement in hypogonadal men. Journal of Clinical Endocrinology & Metabolism, 85, 2670-2677. doi:10.1210/jc.85.8.2670
230. Spinath, F. M., & O'Connor, T. G. (2003). A behavioral genetic study of the overlap between personality and parenting. Journal of Personality, 71, 785-808. doi:10.1111/1467-6494.7105004
231. 125I]RTI-121. Synapse, 21, 364-372. doi:10.1002/syn.890210412
232. Stavrou, I., Zois, C., Chatzikyriakidou, A., Georgiou, I., & Tsatsoulis, A. (2006). Combined estrogen receptor β and estrogen receptor genotypes influence the age of menarche. Human Reproduction, 21, 554- 557. doi:10.1093/humrep/dei326
233. Stavrou, I., Zois, C., Ioannidis, J. P. A., & Tsatsoulis, A. (2002). Association of polymorphisms of the oestrogen receptor α gene with the age of menarche. Human Reproduction, 17, 1101-1105. doi:10.1093/humrep/ 17.4.1101
234. Stoneham, M. D., Everitt, B. J., Hansen, S., Lightman, S. L., & Todd, K. (1985). Oxytocin and sexual behaviour in the male rat and rabbit. Journal of Endocrinology, 107, 97-106. doi:10.1677/joe.0.1070097 Tex. Educ. Code Ann. § 28.004 (Vernon, 2009).
235. Thompson, R. J., Parker, K. J., Hallmayer, J. F., Waugh, C. E., & Gotlib, I. H. (2011). Oxytocin receptor gene polymorphism (rs2254298) interacts with familial risk for psychopathology to predict symptoms of depression and anxiety in adolescent girls. Psychoneuroendocrinology, 36, 144-147. doi:10.1016/j.psyneuen.2010.07.003
236. Tither, J. M., & Ellis, B. J. (2008). Impact of fathers on daughters' age at menarche: A genetically and environmentally controlled sibling study. Developmental Psychology, 44, 1409-1420. doi:10.1037/a0013065
237. Tolman, D. L., & McClelland, S. I. (2011). Normative sexuality development in adolescence: A decade in review, 2000-2009. Journal of Research on Adolescence, 21, 242-255. doi:10.1111/j.1532-7795.2010.00726.x
238. Tucker-Drob, E. M., Rhemtulla, M., Harden, K. P., Turkheimer, E., & Fask, D. (2011). Emergence of a Gene _ Socioeconomic Status interaction on infant mental ability between 10 months and 2 years. Psychological Science, 22, 125-133. doi:10.1177/0956797610392926
239. Turelli, M. (1984). Heritable genetic variation via mutation-selection balance: Lerch's zeta meets the abdominal bristle. Theoretical Population Biology, 25, 138-193. doi:10.1016/0040-5809(84)90017-0
240. Turkheimer, E. (2000). Three laws of behavior genetics and what they mean. Current Directions in Psychological Science, 9, 160-164. doi: 10.1111/1467-8721.00084
241. Udry, J. R. (1979). Age at menarche, at first intercourse, and at first pregnancy. Journal of Biosocial Science, 11, 433-441. doi:10.1017/ S0021932000012517
242. Udry, J. R. (1988). Biological predispositions and social control in adolescent sexual behavior. American Sociological Review, 53, 709-722. doi:10.2307/2095817
243. Udry, J. R. (1995). Sociology and biology: What biology do sociologists need to know? Social Forces, 73, 1267-1278. doi:10.1093/sf/73.4.1267
244. Udry, J. R., Talbert, L. M., & Morris, N. M. (1986). Biosocial foundations for adolescent female sexuality. Demography, 23, 217-230
245. van Bokhoven, I., van Goozen, S. H. M., van Engeland, H., Schaal, B., Arsenault, L., Séguin, J. R.,Tremblay, R. E. (2006). Salivary testosterone and aggression, delinquency, and social dominance in a population-based longitudinal study of adolescent males. Hormones and Behavior, 50, 118-125.
246. Vandenbergh, D. J., Persico, A. M., Hawkins, A. L., Griffin, C. A., Li, X., Jabs, E. W., & Uhl, G. R. (1992). Human dopamine transporter gene (DAT1) maps to chromosome 5p15.3 and displays a VNTR. Genomics, 14, 1104-1106.
247. van den Oord, E. J., & Rowe, D. C. (1999). A cousin study of associations between family demographic characteristics and children's intellectual ability. Intelligence, 27, 251-266. doi:10.1016/S0160-2896(99)00022-7
248. Verweij, K. J. H., Zietsch, B. P., Bailey, J. M., & Martin, N. G. (2009). Shared aetiology of risky sexual behaviour and adolescent misconduct: Genetic and environmental influences. Genes, Brain and Behavior, 8, 107-113. doi:10.1111/j.1601-183X.2008.00456.x
249. Visscher, P. M., Medland, S. E., Ferreira, M. A.-R., Morley, K. I., Zhu, G., Cornes, B. K.,Martin, N. G. (2006). Assumption-free estimation of heritability from genome-wide identity-by-descent sharing between full siblings. PLoS Genetics, 2(3), Article e41. doi:10.1371/journal.pgen.0020041
250. Volkow, N. D., Chang, L., Wang, G.-J., Fowler, J. S., Franceschi, D., Sedler, M.,Logan, J. (2001). Loss of dopamine transporters in methamphetamine abusers recovers with protracted abstinence. Journal of Neuroscience, 21, 9414-9418.
251. Volkow, N. D., Fowler, J. S., Wolf, A. P., Schlyer, D., Shiue, C. Y., Albert, R.,Henn, F. (1990). Effects of chronic cocaine abuse on postsynaptic dopamine receptors. American Journal of Psychiatry, 147, 719-724.
252. 18F-N-methylspiroperidol. Psychiatry Research: Neuroimaging, 67, 11-16.
253. Wachter, K. W., & Bulatao, R. A. (Eds.). (2003). Offspring: Human fertility behavior in biodemographic perspective. Washington, DC: National Academies Press.
254. Wainwright, M. A., Wright, M. J., Geffen, G. M., Luciano, M., & Martin, N. G. (2005). The genetic basis of academic achievement on the Queensland Core Skill Test and its shared genetic variance with IQ. Behavior Genetics, 35, 133-145. doi:10.1007/s10519-004-1014-9
255. Waldron, M., Heath, A. C., Turkheimer, E., Emery, R., Bucholz, K. K., Madden, P. A., & Martin, N. G. (2007). Age at first sexual intercourse and teenage pregnancy in Australian female twins. Twin Research and Human Genetics, 10, 440-449. doi:10.1375/twin.10.3.440
256. Waldron, M., Heath, A. C., Turkheimer, E. N., Emery, R. E., Nelson, E., Bucholz, K. K.,Martin, N. G. (2008). Childhood sexual abuse moderates genetic influences on age at first consensual sexual intercourse in women. Behavior Genetics, 38, 1-10. doi:10.1007/s10519-007-9176-x
257. Walum, H., Westberg, L., Henningsson, S., Neiderhiser, J. M., Reiss, D., Igl, W.,Lichtenstein, P. (2008). Genetic variation in the vasopressin receptor 1a gene (AVPR1A) associates with pair-bonding behavior in humans. PNAS: Proceedings of the National Academy of Sciences, USA, 105, 14153-14156. doi:10.1073/pnas.0803081105
258. Willeit, M., & Praschak-Reider, N. (2010). Imaging the effects of genetic polymorphisms on radioligand binding in the living human brain: A review on genetic neuroreceptor imaging of monoaminergic systems in psychiatry. NeuroImage, 53, 878-892. doi:10.1016/j.neuroimage.2010.04.030
259. Wirshing, D. A., Pierre, J. M., Marder, S. R., Saunders, C. S., & Wirshing, W. C. (2002). Sexual side effects of novel antipsychotic medications.Schizophrenia Research, 56, 25-30.
260. Wyatt, G., Durvasula, R. S., Guthrie, D., Lefranc, E., & Forge, N. (1999). Correlates of first intercourse among women in Jamaica. Archives of Sexual Behavior, 28, 139-157.
261. Yeater, E., Miller, G., Rinehart, J., & Nason, E. (2012). Trauma and sex surveys meet minimal risk standards: Implications for institutional review boards. Psychological Science, 23, 780 -787.
262. Young, L. J., Lim, M. M., Gingrich, B., & Insel, T. R. (2001). Cellular mechanisms of social attachment. Hormones and Behavior, 40, 133- 138.
263. Young, L. J., & Wang, Z. (2004). The neurobiology of pair bonding. Nature Neuroscience, 7, 1048-1054. doi:10.1038/nn1327
264. Zietsch, B. P., Morley, K. I., Shekar, S. N., Verweij, K. J. H., Keller, M. C., Macgregor, S.,Martin, N. G. (2008). Genetic factors predisposing to homosexuality may increase mating success in heterosexuals. Evolution and Human Behavior, 29, 424-433. doi:10.1016/j.evolhumbehav.2008.07.002
265. Zietsch, B. P., Verweij, K. J. H., Bailey, J. M., Wright, M. J., & Martin, N. G. (2010). Genetic and environmental influences on risky sexual behavior and its relationship with personality. Behavior Genetics, 40, 12-21. doi:10.1007/s10519-009-9300-1
266. Zimmer-Gembeck, M. J., & Helfand, M. (2008). Ten years of longitudinal research on U.S. adolescent sexual behavior: Developmental correlates of sexual intercourse, and the importance of age, gender and ethnic background. Developmental Review, 28, 153-224.