Statistical experimental design guided optimization of a one-pot biphasic multienzyme total synthesis of amorpha-4,11-diene

PLoS ONE

Volumn 8, Issue 11, 2013, Pages

  Chen, Xixian ^a   Zhang, Congqiang ^a   Zou, Ruiyang ^a   Zhou, Kang ^a,c   Stephanopoulos, Gregory ^a,c   Too, Heng Phon ^a,b  

^a SINGAPORE MIT ALLIANCE   (Singapore)

^b NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

^c MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

3,3 DIMETHYLALLYL PYROPHOSPHATE; 3,3-DIMETHYLALLYL PYROPHOSPHATE; AMORPHA 4,11 DIENE; AMORPHA 4,11 DIENE SYNTHASE; AMORPHA-4,11-DIENE; FARNESYL DIPHOSPHATE; GERANYLTRANSFERASE; HEMITERPENE; ISOPENTENYL DIPHOSPHATE; ISOPRENOID PHOSPHATE; MEVALONIC ACID; ORGANOPHOSPHORUS COMPOUND; SESQUITERPENE; TRANSFERASE;

AMORPHA-4,11-DIENE SYNTHASE; ARTICLE; CHEMISTRY; METABOLISM; METHODOLOGY; SYNTHESIS;

ALKYL AND ARYL TRANSFERASES; GERANYLTRANSTRANSFERASE; HEMITERPENES; MEVALONIC ACID; ORGANOPHOSPHORUS COMPOUNDS; POLYISOPRENYL PHOSPHATES; RESEARCH DESIGN; SESQUITERPENES;

EID: 84894295608     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0079650     Document Type: Article

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