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84894263037
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note
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2 is commercially available.
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30
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84894245835
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note
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For applications of phosphine-ligated rhodium catalysts in intramolecular silylation reactions, see (23, 24).
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31
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84894244315
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note
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3], from hydrosilylation of the hydrogen acceptor, cyclohexene, is the only major side product.
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-
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32
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84894257579
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note
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The side reaction, cyclohexene hydrosilylation, consumes both the silane and cyclohexene.
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-
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33
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84894257127
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note
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For reactions with 8a, 9a, and 10a, the selectivities of silylation meta and ortho to the methoxy groups are 95.4:4.6, 97.0:3.0, and 97.4:2.6, respectively, as determined by GC analysis. The selectivities for all other 1,3-disubstituted arenes are >99:1.
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34
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0344874124
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T. Ishiyama, Y. Nobuta, J. F. Hartwig, N. Miyaura, Chem. Commun. 23, 2924-2925 (2003).
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35
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84894269587
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note
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For silylations of 16a and 17a, the selectivities for reactions at the 2-positions over all other positions are 98:2 and 97:3, respectively.
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-
-
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36
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84868156095
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H. Tajuddin et al., Chem. Sci. 3, 3505-3515 (2012).
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39
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84894283372
-
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note
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Borylation of benzodioxole following the procedure in (44) afforded a mixture of meta, ortho, and diborylation products (92% yield) in a ratio of 6:33:61. This difference from (38) is likely due to the difference in the amount of the diboron reagent used.
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-
-
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40
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84894226398
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note
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Two constitutional isomers of the borylation product, along with a diborylation product, were obtained in a ratio of 43:18:39 following the literature procedure (44).
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