Commentary: Critical questions, misconceptions and a road map for improving the use of the lymphocyte cytokinesis-block micronucleus assay for in vivo biomonitoring of human exposure to genotoxic chemicals-A HUMN project perspective

Mutation Research - Reviews in Mutation Research

Volumn 759, Issue 1, 2014, Pages 49-58

  Kirsch Volders, Micheline ^a   Bonassi, Stefano ^b   Knasmueller, Siegfried ^c   Holland, Nina ^d   Bolognesi, Claudia ^e   Fenech, Michael F ^f  

^a VRIJE UNIVERSITEIT BRUSSEL   (Belgium)

^b IRCCS SAN RAFFAELE PISANA   (Italy)

^c MEDICAL UNIVERSITY OF VIENNA   (Austria)

^d UNIVERSITY OF CALIFORNIA   (United States)

^e UNIVERSITY OF GENOA   (Italy)

^f CSIRO   (Australia)

Author keywords

Biomonitoring; Chemical genotoxins; Cytokinesis block; In vivo; Lymphocytes; Micronucleus

Indexed keywords

BIOLOGICAL MARKER; CHEMICAL COMPOUND; COMPLEMENTARY DNA; CYTOCHALASIN B; MUTAGENIC AGENT;

APOPTOSIS; BIOLOGICAL MONITORING; CELL CYCLE; CHEMICAL CARCINOGENESIS; CHROMATIN; CHROMOSOME ABERRATION; CYTOKINESIS; DNA ADDUCT; DNA DAMAGE; ENVIRONMENTAL EXPOSURE; EXPOSURE; GENETIC RISK; GENOME; GENOTOXICITY; HEALTH HAZARD; HUMAN; KNOWLEDGE; LYMPHOCYTE; MICRONUCLEUS; MICRONUCLEUS TEST; NOTE; PRIORITY JOURNAL; DNA METHYLATION; DNA PROBE; DNA STRAND BREAKAGE; GENOTOXICITY ASSAY; IN VIVO STUDY; LYMPHOCYTE CYTOKINESIS BLOCK MICRONUCLEUS ASSAY; NUMERICAL CHROMOSOME ABERRATION; OCCUPATIONAL EXPOSURE; STRUCTURAL CHROMOSOME ABERRATION; DRUG EFFECTS; ENVIRONMENTAL MONITORING; TOXICITY;

APOPTOSIS; CYTOKINESIS; DNA DAMAGE; ENVIRONMENTAL MONITORING; HUMANS; LYMPHOCYTES; MICRONUCLEI, CHROMOSOME-DEFECTIVE; MUTAGENS;

EID: 84894274462     PISSN: 13835742     EISSN: 13882139     Source Type: Journal    
DOI: 10.1016/j.mrrev.2013.12.001     Document Type: Note

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