Interferon gamma peptidomimetic targeted to hepatic stellate cells ameliorates acute and chronic liver fibrosis in vivo

Journal of Controlled Release

Volumn 179, Issue 1, 2014, Pages 18-24

  Bansal, Ruchi ^a,b   Prakash, Jai ^a,b   De Ruiter, Marieke ^a   Poelstra, Klaas ^a  

^a UNIVERSITY OF GRONINGEN   (Netherlands)

^b UNIVERSITY OF TWENTE   (Netherlands)

Author keywords

Fibrosis; IFN peptidomimetic; PDGF R recognizing bicyclic peptide; Stellate cells; Targeted delivery

Indexed keywords

ACTIN; COLLAGEN TYPE 1; DESMIN; GAMMA INTERFERON; MESSENGER RNA; PEPTIDOMIMETIC AGENT; PLATELET DERIVED GROWTH FACTOR BETA RECEPTOR; SMOOTH MUSCLE ACTIN, RAT;

ACUTE DISEASE; ANIMAL; C57BL MOUSE; CELL CULTURE; CHRONIC DISEASE; DRUG EFFECTS; GENETICS; LIVER; LIVER CIRRHOSIS, EXPERIMENTAL; MALE; METABOLISM; MOLECULARLY TARGETED THERAPY; MOUSE; PATHOLOGY; RAT; SIGNAL TRANSDUCTION; STELLATE CELL; SYNTHESIS; WISTAR RAT;

ACTINS; ACUTE DISEASE; ANIMALS; CELLS, CULTURED; CHRONIC DISEASE; COLLAGEN TYPE I; DESMIN; HEPATIC STELLATE CELLS; INTERFERON-GAMMA; LIVER; LIVER CIRRHOSIS, EXPERIMENTAL; MALE; MICE; MICE, INBRED C57BL; MOLECULAR TARGETED THERAPY; PEPTIDOMIMETICS; RATS; RATS, WISTAR; RECEPTOR, PLATELET-DERIVED GROWTH FACTOR BETA; RNA, MESSENGER; SIGNAL TRANSDUCTION;

EID: 84894215050     PISSN: 01683659     EISSN: 18734995     Source Type: Journal    
DOI: 10.1016/j.jconrel.2014.01.022     Document Type: Article

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