Peptide-modified albumin carrier explored as a novel strategy for a cell-specific delivery of interferon gamma to treat liver fibrosis

Molecular Pharmaceutics

Volumn 8, Issue 5, 2011, Pages 1899-1909

  Bansal, Ruchi ^a   Prakash, Jai ^a   Ruijter, Marieke De ^a   Beljaars, Leonie ^a   Poelstra, Klaas ^a  

^a UNIVERSITY OF GRONINGEN   (Netherlands)

Author keywords

cyclic peptide; interferon gamma; liver fibrosis; platelet derived growth factor receptor; stellate cells targeting

Indexed keywords

ALPHA SMOOTH MUSCLE ACTIN; CARBON TETRACHLORIDE; COLLAGEN TYPE 1; DRUG CARRIER; GAMMA INTERFERON; HUMAN SERUM ALBUMIN; INTERLEUKIN 1BETA; MACROGOL; PLATELET DERIVED GROWTH FACTOR BETA RECEPTOR; SERYLARGINYLASPARAGINYLLEUCYLISOLEUCYLASPARTYLCYSTEINE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELL INFILTRATION; CONTROLLED STUDY; FIBROBLAST; HUMAN; HUMAN CELL; HUMAN TISSUE; LIVER CIRRHOSIS; LIVER FIBROSIS; MACROPHAGE; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; RAT; STELLATE CELL;

ANIMALS; BIOLOGICAL TRANSPORT; CELL LINE; CELLS, CULTURED; CROSS-LINKING REAGENTS; DRUG CARRIERS; FEMALE; HEPATIC STELLATE CELLS; HUMANS; INTERFERON-GAMMA; LIGANDS; LIVER CIRRHOSIS; MACROPHAGE ACTIVATION; MALE; MICE; MICE, INBRED BALB C; PEPTIDES, CYCLIC; RECEPTOR, PLATELET-DERIVED GROWTH FACTOR BETA; SERUM ALBUMIN; SIGNAL TRANSDUCTION; STAT1 TRANSCRIPTION FACTOR; TISSUE DISTRIBUTION;

EID: 80053491358     PISSN: 15438384     EISSN: 15438392     Source Type: Journal    
DOI: 10.1021/mp200263q     Document Type: Article

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