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Volumn 27, Issue 1, 2014, Pages 46-52

Manipulating immune cells for adoptive immunotherapy of cancer

Author keywords

[No Author keywords available]

Indexed keywords

ANIMALS; HUMANS; IMMUNITY, INNATE; IMMUNOTHERAPY, ADOPTIVE; KILLER CELLS, NATURAL; NEOPLASMS; T-LYMPHOCYTES;

EID: 84894094894     PISSN: 09527915     EISSN: 18790372     Source Type: Journal    
DOI: 10.1016/j.coi.2014.01.008     Document Type: Review
Times cited : (41)

References (84)
  • 4
    • 0033554726 scopus 로고    scopus 로고
    • Two subsets of memory T lymphocytes with distinct homing potentials and effector functions
    • Sallusto F., Lenig D., Forster R., Lipp M., Lanzavecchia A. Two subsets of memory T lymphocytes with distinct homing potentials and effector functions. Nature 1999, 401:708-712.
    • (1999) Nature , vol.401 , pp. 708-712
    • Sallusto, F.1    Lenig, D.2    Forster, R.3    Lipp, M.4    Lanzavecchia, A.5
  • 5
    • 0035937587 scopus 로고    scopus 로고
    • Preferential localization of effector memory cells in nonlymphoid tissue
    • Masopust D., Vezys V., Marzo A.L., Lefrançois L. Preferential localization of effector memory cells in nonlymphoid tissue. Science 2001, 291:2413-2417.
    • (2001) Science , vol.291 , pp. 2413-2417
    • Masopust, D.1    Vezys, V.2    Marzo, A.L.3    Lefrançois, L.4
  • 12
    • 0037432776 scopus 로고    scopus 로고
    • Defective CD8 T cell memory following acute infection without CD4 T cell help
    • Sun J.C., Bevan M.J. Defective CD8 T cell memory following acute infection without CD4 T cell help. Science 2003, 300:339-342.
    • (2003) Science , vol.300 , pp. 339-342
    • Sun, J.C.1    Bevan, M.J.2
  • 20
    • 0033662405 scopus 로고    scopus 로고
    • + T cell-mediated tumor rejection involves inhibition of angiogenesis that is dependent on IFN gamma receptor expression by nonhematopoeitic cells
    • + T cell-mediated tumor rejection involves inhibition of angiogenesis that is dependent on IFN gamma receptor expression by nonhematopoeitic cells. Immunity 2000, 12:677-686.
    • (2000) Immunity , vol.12 , pp. 677-686
    • Qin, Z.1    Blankenstein, T.2
  • 22
    • 0033195032 scopus 로고    scopus 로고
    • Eotaxin. An essential mediator of eosinophil trafficking into mucosal tissues
    • Rothenberg M.E. Eotaxin. An essential mediator of eosinophil trafficking into mucosal tissues. Am J Respir Cell Mol Biol 1999, 21:291-295.
    • (1999) Am J Respir Cell Mol Biol , vol.21 , pp. 291-295
    • Rothenberg, M.E.1
  • 25
    • 77950196277 scopus 로고    scopus 로고
    • Th17 cells in tumour immunity and immunotherapy
    • Zou W., Restifo N. Th17 cells in tumour immunity and immunotherapy. Nat Rev Immunol 2010, 10:248-256.
    • (2010) Nat Rev Immunol , vol.10 , pp. 248-256
    • Zou, W.1    Restifo, N.2
  • 27
    • 79952343500 scopus 로고    scopus 로고
    • γδ T-cell killing of primary follicular lymphoma cells is dramatically potentiated by GA101, a type II glycoengineered anti-CD20 monoclonal antibody
    • Braza M.S., Klein B., Fiol G., Rossi J.-F. γδ T-cell killing of primary follicular lymphoma cells is dramatically potentiated by GA101, a type II glycoengineered anti-CD20 monoclonal antibody. Haematologica 2011, 96:400-407.
    • (2011) Haematologica , vol.96 , pp. 400-407
    • Braza, M.S.1    Klein, B.2    Fiol, G.3    Rossi, J.-F.4
  • 29
    • 77951894970 scopus 로고    scopus 로고
    • Vγ9Vδ2 T lymphocytes efficiently recognize and kill zoledronate-sensitized, imatinib-sensitive, and imatinib-resistant chronic myelogenous leukemia cells
    • D'Asaro M., La Mendola C., Di Liberto D., Orlando V., Todaro M., Spina M., Guggino G., Meraviglia S., Caccamo N., Messina A., et al. Vγ9Vδ2 T lymphocytes efficiently recognize and kill zoledronate-sensitized, imatinib-sensitive, and imatinib-resistant chronic myelogenous leukemia cells. J Immunol 2010, 184:3260-3268.
    • (2010) J Immunol , vol.184 , pp. 3260-3268
    • D'Asaro, M.1    La Mendola, C.2    Di Liberto, D.3    Orlando, V.4    Todaro, M.5    Spina, M.6    Guggino, G.7    Meraviglia, S.8    Caccamo, N.9    Messina, A.10
  • 30
    • 0034660687 scopus 로고    scopus 로고
    • Stimulation of γδ T cells by aminobisphosphonates and induction of antiplasma cell activity in multiple myeloma
    • Kunzmann V., Bauer E., Feurle J., Tony F.W., Hans-Peter, Wilhelm M. Stimulation of γδ T cells by aminobisphosphonates and induction of antiplasma cell activity in multiple myeloma. Blood 2000, 96:384-392.
    • (2000) Blood , vol.96 , pp. 384-392
    • Kunzmann, V.1    Bauer, E.2    Feurle, J.3    Tony, F.W.4    Hans-Peter5    Wilhelm, M.6
  • 33
    • 33846813974 scopus 로고    scopus 로고
    • Safety profile and anti-tumor effects of adoptive immunotherapy using gamma-delta T cells against advanced renal cell carcinoma: a pilot study
    • Kobayashi H., Tanaka Y., Yagi J., Osaka Y., Nakazawa H., Uchiyama T., Minato N., Toma H. Safety profile and anti-tumor effects of adoptive immunotherapy using gamma-delta T cells against advanced renal cell carcinoma: a pilot study. Cancer Immunol Immunother 2007, 56:469-476.
    • (2007) Cancer Immunol Immunother , vol.56 , pp. 469-476
    • Kobayashi, H.1    Tanaka, Y.2    Yagi, J.3    Osaka, Y.4    Nakazawa, H.5    Uchiyama, T.6    Minato, N.7    Toma, H.8
  • 35
    • 41149139540 scopus 로고    scopus 로고
    • Chemokine receptors expression and migration potential of tumor-infiltrating and peripheral-expanded Vg9Vd2 T cells from renal cell carcinoma patients
    • Viey E., Lucas C., Romagne F., Escudier B., Chouaib S., Caignard A. Chemokine receptors expression and migration potential of tumor-infiltrating and peripheral-expanded Vg9Vd2 T cells from renal cell carcinoma patients. J Immunother 2008, 31:313-323. 10.1097/CJI.1090b1013e3181609988.
    • (2008) J Immunother , vol.31 , pp. 313-323
    • Viey, E.1    Lucas, C.2    Romagne, F.3    Escudier, B.4    Chouaib, S.5    Caignard, A.6
  • 36
    • 77954143558 scopus 로고    scopus 로고
    • γδ T cell effector functions: a blend of innate programming and acquired plasticity
    • Bonneville M., O'Brien R.L., Born W.K. γδ T cell effector functions: a blend of innate programming and acquired plasticity. Nat Rev Immunol 2010, 10:467-478.
    • (2010) Nat Rev Immunol , vol.10 , pp. 467-478
    • Bonneville, M.1    O'Brien, R.L.2    Born, W.K.3
  • 37
    • 0037455013 scopus 로고    scopus 로고
    • Human T cell receptor γδ cells recognize endogenous mevalonate metabolites in tumor cells
    • Gober H.-J., Kistowska M., Angman L., Jenö P., Mori L., De Libero G. Human T cell receptor γδ cells recognize endogenous mevalonate metabolites in tumor cells. J Exp Med 2003, 197:163-168.
    • (2003) J Exp Med , vol.197 , pp. 163-168
    • Gober, H.-J.1    Kistowska, M.2    Angman, L.3    Jenö, P.4    Mori, L.5    De Libero, G.6
  • 44
    • 84880923112 scopus 로고    scopus 로고
    • Gamma delta T cells are activated by polysaccharide K (PSK) and contribute to the anti-tumor effect of PSK
    • Inatsuka C., Yang Y., Gad E., Rastetter L., Disis M., Lu H. Gamma delta T cells are activated by polysaccharide K (PSK) and contribute to the anti-tumor effect of PSK. Cancer Immunol Immunother 2013, 62:1335-1345.
    • (2013) Cancer Immunol Immunother , vol.62 , pp. 1335-1345
    • Inatsuka, C.1    Yang, Y.2    Gad, E.3    Rastetter, L.4    Disis, M.5    Lu, H.6
  • 45
    • 84879112769 scopus 로고    scopus 로고
    • Protective role of the inflammatory CCR2/CCL2 chemokine pathway through recruitment of Type 1 cytotoxic γδ T lymphocytes to tumor beds
    • Lança T., Costa M.F., Gonçalves-Sousa N., Rei M., Grosso A.R., Penido C., Silva-Santos B. Protective role of the inflammatory CCR2/CCL2 chemokine pathway through recruitment of Type 1 cytotoxic γδ T lymphocytes to tumor beds. J Immunol 2013, 190:6673-6680.
    • (2013) J Immunol , vol.190 , pp. 6673-6680
    • Lança, T.1    Costa, M.F.2    Gonçalves-Sousa, N.3    Rei, M.4    Grosso, A.R.5    Penido, C.6    Silva-Santos, B.7
  • 46
    • 67650032911 scopus 로고    scopus 로고
    • Clinical and immunological evaluation of zoledronate-activated Vγ9γδ T-cell-based immunotherapy for patients with multiple myeloma
    • Abe Y., Muto M., Nieda M., Nakagawa Y., Nicol A., Kaneko T., Goto S., Yokokawa K., Suzuki K. Clinical and immunological evaluation of zoledronate-activated Vγ9γδ T-cell-based immunotherapy for patients with multiple myeloma. Exp Hematol 2009, 37:956-968.
    • (2009) Exp Hematol , vol.37 , pp. 956-968
    • Abe, Y.1    Muto, M.2    Nieda, M.3    Nakagawa, Y.4    Nicol, A.5    Kaneko, T.6    Goto, S.7    Yokokawa, K.8    Suzuki, K.9
  • 47
    • 50649102839 scopus 로고    scopus 로고
    • Phase-I study of Innacell γδ™, an autologous cell-therapy product highly enriched in γ9δ2 T lymphocytes, in combination with IL-2, in patients with metastatic renal cell carcinoma
    • Bennouna J., Bompas E., Neidhardt E., Rolland F., Philip I., Galéa C., Salot S., Saiagh S., Audrain M., Rimbert M., et al. Phase-I study of Innacell γδ™, an autologous cell-therapy product highly enriched in γ9δ2 T lymphocytes, in combination with IL-2, in patients with metastatic renal cell carcinoma. Cancer Immunol Immunother 2008, 57:1599-1609.
    • (2008) Cancer Immunol Immunother , vol.57 , pp. 1599-1609
    • Bennouna, J.1    Bompas, E.2    Neidhardt, E.3    Rolland, F.4    Philip, I.5    Galéa, C.6    Salot, S.7    Saiagh, S.8    Audrain, M.9    Rimbert, M.10
  • 48
    • 79960903905 scopus 로고    scopus 로고
    • Phase I/II study of adoptive transfer of γδ T cells in combination with zoledronic acid and IL-2 to patients with advanced renal cell carcinoma
    • Kobayashi H., Tanaka Y., Yagi J., Minato N., Tanabe K. Phase I/II study of adoptive transfer of γδ T cells in combination with zoledronic acid and IL-2 to patients with advanced renal cell carcinoma. Cancer Immunol Immunother 2011, 60:1075-1084.
    • (2011) Cancer Immunol Immunother , vol.60 , pp. 1075-1084
    • Kobayashi, H.1    Tanaka, Y.2    Yagi, J.3    Minato, N.4    Tanabe, K.5
  • 49
    • 78650386896 scopus 로고    scopus 로고
    • Zoledronate-activated Vγ9γ T cell-based immunotherapy is feasible and restores the impairment of gamma; T cells in patients with solid tumors
    • Noguchi A., Kaneko T., Kamigaki T., Fujimoto K., Ozawa M., Saito M., Ariyoshi N., Goto S. Zoledronate-activated Vγ9γ T cell-based immunotherapy is feasible and restores the impairment of gamma; T cells in patients with solid tumors. Cytotherapy 2012, 13:92-97.
    • (2012) Cytotherapy , vol.13 , pp. 92-97
    • Noguchi, A.1    Kaneko, T.2    Kamigaki, T.3    Fujimoto, K.4    Ozawa, M.5    Saito, M.6    Ariyoshi, N.7    Goto, S.8
  • 51
    • 57949103408 scopus 로고    scopus 로고
    • Zoledronate facilitates large-scale ex vivo expansion of functional gamma; T cells from cancer patients for use in adoptive immunotherapy
    • Kondo M., Sakuta K., Noguchi A., Ariyoshi N., Sato K., Sato S., Sato K., Hosoi A., Nakajima J., Yoshida Y., et al. Zoledronate facilitates large-scale ex vivo expansion of functional gamma; T cells from cancer patients for use in adoptive immunotherapy. Cytotherapy 2008, 10:842-856.
    • (2008) Cytotherapy , vol.10 , pp. 842-856
    • Kondo, M.1    Sakuta, K.2    Noguchi, A.3    Ariyoshi, N.4    Sato, K.5    Sato, S.6    Sato, K.7    Hosoi, A.8    Nakajima, J.9    Yoshida, Y.10
  • 52
    • 0038040624 scopus 로고    scopus 로고
    • Expression of CD1d by myelomonocytic leukemias provides a target for cytotoxic NKT cells
    • Metelitsa L.S., Weinberg K.I., Emanuel P.D., Seeger R.C. Expression of CD1d by myelomonocytic leukemias provides a target for cytotoxic NKT cells. Leukemia 2003, 17:1068-1077.
    • (2003) Leukemia , vol.17 , pp. 1068-1077
    • Metelitsa, L.S.1    Weinberg, K.I.2    Emanuel, P.D.3    Seeger, R.C.4
  • 58
    • 0038543513 scopus 로고    scopus 로고
    • A reversible defect in natural killer T cell function characterizes the progression of premalignant to malignant multiple myeloma
    • Dhodapkar M.V., Geller M.D., Chang D.H., Shimizu K., Fujii S., Dhodapkar K.M., Krasovsky J. A reversible defect in natural killer T cell function characterizes the progression of premalignant to malignant multiple myeloma. J Exp Med 2003, 197:1667-1676.
    • (2003) J Exp Med , vol.197 , pp. 1667-1676
    • Dhodapkar, M.V.1    Geller, M.D.2    Chang, D.H.3    Shimizu, K.4    Fujii, S.5    Dhodapkar, K.M.6    Krasovsky, J.7
  • 59
    • 0022349817 scopus 로고
    • Observations on the systemic administration of autologous lymphokine-activated killer cells and recombinant interleukin-2 to patients with metastatic cancer
    • Rosenberg S.A., Lotze M.T., Muul L.M., Leitman S., Chang A.E., Ettinghausen S.E., Matory Y.L., Skibber J.M., Shiloni E., Vetto J.T., et al. Observations on the systemic administration of autologous lymphokine-activated killer cells and recombinant interleukin-2 to patients with metastatic cancer. N Engl J Med 1985, 313:1485-1492.
    • (1985) N Engl J Med , vol.313 , pp. 1485-1492
    • Rosenberg, S.A.1    Lotze, M.T.2    Muul, L.M.3    Leitman, S.4    Chang, A.E.5    Ettinghausen, S.E.6    Matory, Y.L.7    Skibber, J.M.8    Shiloni, E.9    Vetto, J.T.10
  • 60
    • 0022530989 scopus 로고
    • Dissection of the lymphokine-activated killer phenomenon. Relative contribution of peripheral blood natural killer cells and T lymphocytes to cytolysis
    • Phillips J.H., Lanier L.L. Dissection of the lymphokine-activated killer phenomenon. Relative contribution of peripheral blood natural killer cells and T lymphocytes to cytolysis. J Exp Med 1986, 164:814-825.
    • (1986) J Exp Med , vol.164 , pp. 814-825
    • Phillips, J.H.1    Lanier, L.L.2
  • 64
    • 51549100478 scopus 로고    scopus 로고
    • Adoptive transfer of gene-modified primary NK cells can specifically inhibit tumor progression in vivo
    • Pegram H.J., Jackson J.T., Smyth M.J., Kershaw M.H., Darcy P.K. Adoptive transfer of gene-modified primary NK cells can specifically inhibit tumor progression in vivo. J Immunol 2008, 181:3449-3455.
    • (2008) J Immunol , vol.181 , pp. 3449-3455
    • Pegram, H.J.1    Jackson, J.T.2    Smyth, M.J.3    Kershaw, M.H.4    Darcy, P.K.5
  • 65
    • 0037103311 scopus 로고    scopus 로고
    • Retargeting of natural killer-cell cytolytic activity to ErbB2-expressing cancer cells results in efficient and selective tumor cell destruction
    • Uherek C., Tonn T., Uherek B., Becker S., Schnierle B., Klingemann H.G., Wels W. Retargeting of natural killer-cell cytolytic activity to ErbB2-expressing cancer cells results in efficient and selective tumor cell destruction. Blood 2002, 100:1265-1273.
    • (2002) Blood , vol.100 , pp. 1265-1273
    • Uherek, C.1    Tonn, T.2    Uherek, B.3    Becker, S.4    Schnierle, B.5    Klingemann, H.G.6    Wels, W.7
  • 66
    • 0042847257 scopus 로고    scopus 로고
    • Fas ligand on tumor cells mediates inactivation of neutrophils
    • Chen Y.L., Chen S.H., Wang J.Y., Yang B.C. Fas ligand on tumor cells mediates inactivation of neutrophils. J Immunol 2003, 171:1183-1191.
    • (2003) J Immunol , vol.171 , pp. 1183-1191
    • Chen, Y.L.1    Chen, S.H.2    Wang, J.Y.3    Yang, B.C.4
  • 67
    • 0035170119 scopus 로고    scopus 로고
    • IL-6 secretion by a rat T9 glioma clone induces a neutrophil-dependent antitumor response with resultant cellular, antiglioma immunity
    • Graf M.R., Prins R.M., Merchant R.E. IL-6 secretion by a rat T9 glioma clone induces a neutrophil-dependent antitumor response with resultant cellular, antiglioma immunity. J Immunol 2001, 166:121-129.
    • (2001) J Immunol , vol.166 , pp. 121-129
    • Graf, M.R.1    Prins, R.M.2    Merchant, R.E.3
  • 69
    • 0034235913 scopus 로고    scopus 로고
    • Targeted macrophage cytotoxicity using a nonreplicative live vector expressing a tumor-specific single-chain variable region fragment
    • Paul S., Snary D., Hoebeke J., Allen D., Balloul J.M., Bizouarne N., Dott K., Geist M., Hilgers J., Kieny M.P., et al. Targeted macrophage cytotoxicity using a nonreplicative live vector expressing a tumor-specific single-chain variable region fragment. Hum Gene Ther 2000, 11:1417-1428.
    • (2000) Hum Gene Ther , vol.11 , pp. 1417-1428
    • Paul, S.1    Snary, D.2    Hoebeke, J.3    Allen, D.4    Balloul, J.M.5    Bizouarne, N.6    Dott, K.7    Geist, M.8    Hilgers, J.9    Kieny, M.P.10
  • 70
    • 1542405217 scopus 로고    scopus 로고
    • Eosinophils: 'new' roles for 'old' cells
    • Munitz A., Levi-Schaffer F. Eosinophils: 'new' roles for 'old' cells. Allergy 2004, 59:268-275.
    • (2004) Allergy , vol.59 , pp. 268-275
    • Munitz, A.1    Levi-Schaffer, F.2
  • 74
    • 52649104087 scopus 로고    scopus 로고
    • Isolation of human NK cells and generation of LAK activity
    • (Chapter 7): Unit 7.7
    • Whiteside T.L. Isolation of human NK cells and generation of LAK activity. Curr Protoc Immunol 2001, (Chapter 7): Unit 7.7.
    • (2001) Curr Protoc Immunol
    • Whiteside, T.L.1
  • 75
    • 77956492375 scopus 로고    scopus 로고
    • Isolation and functional use of human NKT cells
    • (Chapter 14): Unit 14.11
    • Exley M.A., Wilson B., Balk S.P. Isolation and functional use of human NKT cells. Curr Protoc Immunol 2010, (Chapter 14): Unit 14.11.
    • (2010) Curr Protoc Immunol
    • Exley, M.A.1    Wilson, B.2    Balk, S.P.3
  • 76
    • 84877141949 scopus 로고    scopus 로고
    • Extensive expansion of primary human gamma delta T cells generates cytotoxic effector memory cells that can be labeled with Feraheme for cellular MRI
    • Siegers G.M., Ribot E.J., Keating A., Foster P.J. Extensive expansion of primary human gamma delta T cells generates cytotoxic effector memory cells that can be labeled with Feraheme for cellular MRI. Cancer Immunol Immunother 2012, 62:571-583.
    • (2012) Cancer Immunol Immunother , vol.62 , pp. 571-583
    • Siegers, G.M.1    Ribot, E.J.2    Keating, A.3    Foster, P.J.4
  • 77
    • 77956489518 scopus 로고    scopus 로고
    • Generation, isolation, and maintenance of human mast cells and mast cell lines derived from peripheral blood or cord blood
    • (Chapter 7): Unit 7.37
    • Radinger M., Jensen B.M., Kuehn H.S., Kirshenbaum A., Gilfillan A.M. Generation, isolation, and maintenance of human mast cells and mast cell lines derived from peripheral blood or cord blood. Curr Protoc Immunol 2010, (Chapter 7): Unit 7.37.
    • (2010) Curr Protoc Immunol
    • Radinger, M.1    Jensen, B.M.2    Kuehn, H.S.3    Kirshenbaum, A.4    Gilfillan, A.M.5
  • 79
    • 84856248594 scopus 로고    scopus 로고
    • Isolation and differentiation of monocytes-macrophages from human blood
    • Vijayan D. Isolation and differentiation of monocytes-macrophages from human blood. Methods Mol Biol 2012, 844:183-187.
    • (2012) Methods Mol Biol , vol.844 , pp. 183-187
    • Vijayan, D.1
  • 80
    • 56149088519 scopus 로고    scopus 로고
    • Functionally competent eosinophils differentiated ex vivo in high purity from normal mouse bone marrow
    • Dyer K.D., Moser J.M., Czapiga M., Siegel S.J., Percopo C.M., Rosenberg H.F. Functionally competent eosinophils differentiated ex vivo in high purity from normal mouse bone marrow. J Immunol 2008, 181:4004-4009.
    • (2008) J Immunol , vol.181 , pp. 4004-4009
    • Dyer, K.D.1    Moser, J.M.2    Czapiga, M.3    Siegel, S.J.4    Percopo, C.M.5    Rosenberg, H.F.6
  • 81
    • 68849113457 scopus 로고    scopus 로고
    • Single-chain antibodies that target lentiviral vectors to MHC class II on antigen-presenting cells
    • Gennari F., Lopes L., Verhoeyen E., Marasco W., Collins M.K. Single-chain antibodies that target lentiviral vectors to MHC class II on antigen-presenting cells. Hum Gene Ther 2009, 20:554-562.
    • (2009) Hum Gene Ther , vol.20 , pp. 554-562
    • Gennari, F.1    Lopes, L.2    Verhoeyen, E.3    Marasco, W.4    Collins, M.K.5
  • 82
    • 79251557166 scopus 로고    scopus 로고
    • Evaluation of transduction efficiency in macrophage colony-stimulating factor differentiated human macrophages using HIV-1 based lentiviral vectors
    • Leyva F.J., Anzinger J.J., McCoy J.P., Kruth H.S. Evaluation of transduction efficiency in macrophage colony-stimulating factor differentiated human macrophages using HIV-1 based lentiviral vectors. BMC Biotechnol 2011, 11:13.
    • (2011) BMC Biotechnol , vol.11 , pp. 13
    • Leyva, F.J.1    Anzinger, J.J.2    McCoy, J.P.3    Kruth, H.S.4
  • 83
    • 80051720194 scopus 로고    scopus 로고
    • Chimeric antigen receptor-modified T cells in chronic lymphoid leukemia
    • Porter D.L., Levine B.L., Kalos M., Bagg A., June C.H. Chimeric antigen receptor-modified T cells in chronic lymphoid leukemia. N Engl J Med 2011, 365:725-733.
    • (2011) N Engl J Med , vol.365 , pp. 725-733
    • Porter, D.L.1    Levine, B.L.2    Kalos, M.3    Bagg, A.4    June, C.H.5
  • 84
    • 84872865451 scopus 로고    scopus 로고
    • Inhibition of intracellular antiviral defense mechanisms augments lentiviral transduction of human natural killer cells: implications for gene therapy
    • Sutlu T., Nystrom S., Gilljam M., Stellan B., Applequist S.E., Alici E. Inhibition of intracellular antiviral defense mechanisms augments lentiviral transduction of human natural killer cells: implications for gene therapy. Hum Gene Ther 2012, 23:1090-1100.
    • (2012) Hum Gene Ther , vol.23 , pp. 1090-1100
    • Sutlu, T.1    Nystrom, S.2    Gilljam, M.3    Stellan, B.4    Applequist, S.E.5    Alici, E.6


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