Eosinophils: 'New' roles for 'old' cells

Allergy: European Journal of Allergy and Clinical Immunology

Volumn 59, Issue 3, 2004, Pages 268-275

  Munitz, A ^a   Levi Schaffer, F ^a  

^a HEBREW UNIVERSITY OF JERUSALEM   (Israel)

Author keywords

Allergy; Angiogenesis; Eosinophils; Fibrosis; Inhibitory receptors

Indexed keywords

ALLERGY; ANGIOGENESIS; CARCINOMA; CELL ACTIVATION; CELL FUNCTION; CELL MATURATION; CELL SURVIVAL; CELL TYPE; ENDOTHELIUM CELL; EOSINOPHIL; FIBROBLAST; FIBROSIS; INFLAMMATION; MAST CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; REVIEW; SIGNAL TRANSDUCTION; TISSUE REPAIR; TUMOR;

ANIMALS; EOSINOPHILS; FIBROSIS; HUMANS; HYPERSENSITIVITY; MAST CELLS; NEOPLASMS; NEOVASCULARIZATION, PHYSIOLOGIC;

EID: 1542405217     PISSN: 01054538     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1398-9995.2003.00442.x     Document Type: Review

References (68)

1. GIEMBYCZ MA, LINDSAY MA. Pharmacology of the eosinophil. Pharmacol Rev 1999;51:213-336.
2. ROTHENBERG ME, MISHRA A, BRANDT EB, HOGAN SP. Gastrointestinal eosinophils. Immunol Rev 2003;14:99-111.
3. BOCHNER BS, SCHLEIMER RP. Mast cells, basophils and eosinophils: distinct but overlapping pathways for recruitment. Immunol Rev 2001;179:5-15.
4. BROIDE D, SRIRAMARAO P. Eosinophil trafficking to sites of allergic inflammation. Immunol Rev 2001;179:163-172.
5. GLEICH GJ. Mechanisms of eosinophil-associated inflammation. J Allergy Clin Immunol 2000;105:651-663.
6. SIMON HU. Integrin expression by eosinophils. Allergy 2000;55:791-792.
7. BEHM CA, OVINGTON KS. The role of eosinophils in parasite helminth infections: insights from genetically modified mice. Parasitol Today 2000;16:202-209.
8. MEEUSEN ENT, BALIE A. Do eosinophils have a role in the killing of helminth parasites? Parasitol Today 2000;16: 95-101.
9. LEE NA, GELFAND EW, LEE JJ. Pulmonary T cells and eosinophils: coconspirators or independent triggers of allergic respiratory pathology. J Allergy Clin Immunol 2001;107:945-957.
10. BUSSE WW, LEMANSKE RF Jr. Asthma. N Engl J Med 2001;344:350-362.
11. LOUIS R, SELE J, HENKET M, CATALDO D, BETTIOL J, SEIDEN L et al. Sputum eosinophilcount in large population of patients with mild to moderate steroid-naïve asthma distribution and relationship with methancholine bronchial hyperresponsiveness. Allergy 2002; 57:907-912.
12. BOUSQUET J, CHANEZ P, YVES LACOSTE J, BARNEON G, GHAVANIAN N, ENANDER I et al. Eosinophilic inflammation in asthma. N Engl J Med 1990;323:1033-1039.
13. ROSENBERG HF, DAMACHOWSKE JB. Eosinophils eosinophil ribonucleases and their role in host defense against respiratory virus pathogens. J Leukoc Biol 2001;70:691-698.
14. ZHEUTLIN LM, ACKERMAN SJ, GLEICH GJ, THOMAS LL. Stimulation of basophil and rat mast cell histamine release by eosinophil granule-derived cationic proteins. J Immunol 1984;133: 2180-2185.
15. HENDERSON WR, CHI EY, JONG EC, KLEBANOFF SJ. Mast cell-mediated tumor-cell cytotoxicity. Role of the peroxidase system. J Exp Med 1981;153:520-533.
16. PILIPONSKY AM, PICKHOLTZ D, GLEICH GJ, LEVI-SCHAFFER F. Eosinophils activate mast cells to release histamine. Int Arch Allergy Immunol 1999;118: 202-203.
17. PILIPONSKY AM, PICKHOLTZ D, GLEICH GJ, LEVI-SCHAFFER F. Human eosinophils induce histamine release from antigen-activated rat peritoneal mast cells: a possible role for mast cells in the late phase allergic reactions. J Allergy Clin Immunol 2001;107:993-1000.
18. OKAYAMA Y, EL-LATI SG, LEIFERMAN KM, CHURCH MK. Eosinophil granule proteins inhibit substance P-induced histamine release from human skin mast cells. J Allergy Clin Immunol 1994; 93:900-909.
19. PATELLA V, de CRESCENZO G, MARINO I, GENOVESE A, ADT M, GLEICH GJ et al. Eosinophil granule proteins activate human heart mast cells. J Immunol 1996;157:1219-1225.
20. PATELLA V, DE CRESCENZO G, MARINO I, GENOVESE A, ADT M, GLEICH GJ et al. Eosinophil granule proteins are selective activators of human mast cells. Int Arch Allergy Immunol 1997;113:200-202.
21. PILIPONSKY AM, GLEICH GJ, NAGLER A, BAR I, LEVI-SCHAFFER F. Non-IgE-dependent activation of human lung and cord blood-derived mast cells is induced by eosinophil major basic protein and modulated by the membrane form of stem cell factor. Blood 2003;101: 1898-1904.
22. TSAI M, TAKEISHI T, THOMPSON H, LANGLEY KE, ZSEBO KM, METCALFE DD et al. Induction of mast cell proliferation maturation and heparin synthesis by the rat c-kit ligand stem cell factor. Proc Natl Acad Sci USA 1991;88: 6382-6386.
23. IEMURA A, TSAI M, ANDO A, WERSHIL BK, GALLI SJ. The c-kit ligand stem cell factor promotes mast cell survival by suppressing apoptosis. Am J Pathol 1994;144:321-328.
24. COLUMBO M, HOROWITZ EM, BOTANA LM, MACGLASHAN DW Jr., BOCHNER BS, GILLIS S et al. The human recombinant c-kit receptor ligand rhSCF induces mediator release from human cutaneous mast cells and peripheral blood basophils. J Immunol 1992;149:599-608.
25. BISCHOFF SC, DAHINDEN CA. c-kit ligand a unique potentiator of mediator release by human lung mast cells. J Exp Med 1992;175:237-244.
26. BISCHOFF SC, SCHWENBERG S, RAAB R, MANNS MP. Functional properties of human intestinal mast cells cultured in a new culture system: enhancement of IgE receptor-dependent mediator release and response to stem cell factor. J Immunol 1997;159:5560-5567.
27. HARTMAN ML, PILIPONSKY AM, TEMKIN V, LEVI-SCHAFFER F. Human peripheral blood eosinophils express stem cell factor. Blood 2001;97:1086-1091.
28. KOBAYASHI H, GLEICH GJ, BUTTERFIELD JH, KITA H. Human eosinophils produce neutrophins and secrete nerve growth factor on immunologic stimuli. Blood 2002;99:2214-2220.
29. HORIGOME K, BULLOCK ED, JOHNSON EM Jr. Effects of nerve growth factor on rat peritoneal mast cells survival promotion and immediate-early gene induction. J Biol Chem 1994;269:2695-2702.
30. SMITH SJ, LEVI-SCHAFFER F. Mast cell eosinophil-fibroblast cross-talk in allergic inflammation. In: ROBINSON DS, editor. Asthma and allergic diseases. London: Karger Press, 2000:81-92.
31. MAUCH C, KRIEG T. Fibroblast-matrix interactions and their role in the pathogenesis of fibrosis. Rheum Dis Clin North Am 1990;16:93-107.
32. HERNNAS J, SARNSTRAND B, LINDROTH P, PERTERSON CG, VENGE P, MALMSTORM A. Eosinophils cationic protein alters proteoglycan metabolism in human lung fibroblast cultures. Eur J Cell Biol 1992;59:352-363.
33. ROCHESTER CL, ACKERMAN SS, ZHENG T, ELIAS JA. Eosinophil fibroblast interactions granule major basic protein interacts with interleukin 1 and transforming growth factor-β in the stimulation of lung fibroblast interleukin 6-type cytokine production. J Immunol 1996;156:4449-4456.
34. LEVI-SCHAFFER F, GARBUZENKO E, RUBIN A, REICH R, PICKHOLTZ D, GILLERY P et al. Human eosinophils regulate human lung and skin-derived fibroblast properties in vitro: a role for transforming growth factor-β. Proc Natl Acad Sci USA 1999;96:9660-9665.
35. HOSHINO M, TAKAHASHI M, AOIKE N. Expression of vascular endothelial growth factor basic fibroblast growth factor and angiogenin immunoreactivity in asthmatic airways and its relationship to angiogenesis. J Allergy Clin Immunol 2001;107:295-301.
36. SOLOMON A, ALOE L, PE'ER J, FRUCHT-PERY J, BONINI S, LEVI-SCHAFFER F. Nerve growth factor is preformed in and activates human peripheral blood eosinophils. J Allergy Clin Immuol 1998;102:454-460.
37. HORIUCHI T, WELLER P. Expression of vascular endothelial growth factor by human eosinophils: upregulation by granulocyte macrophage colony-stimulating factor and interleukin-5. Am J Respir Cell Mol Biol 1997;17:70-77.
38. DOUCET C, BROUTY-BOYE D, POTTIN-C C, CANONICA GW, JASMIN C, AZZARONE B. Interleukin (IL) 4 and IL-13 act on human lung fibroblasts: implication in asthma. J Clin Invest 1998;101:2129-2139.
39. RICHTER A, PUDDICOMBE SM, LORDAN JL, BUCCHIERI F, WILSON SJ, DJUKANOVIC R et al. The contribution of interleukin (IL) 4 and IL-13 to the epithelial-mesenchymal trophic unit in asthma. Am J Respir Cell Mol Biol 2001;25:385-391.
40. SIMON P, YING S, WANGOO A, YEE-EAN O, LEVI-SCHAFFER F, KAY BA. The relationship between allergen-induced tissue eosinophilia and markers of repair and remodeling in human atopic skin. J Immunol 2002;169:4604-4612.
41. SCHWINGSHACKL A, DUSZYK M, BROWN N, MOQBEL R. Human eosinophils release matrix metalloproteinase-9 on stimulation with TNF-alpha. J Allergy Clin Immunol 1999;104:983-989.
42. HOSHINO M, TAKAHASHI M, AOIKE N. Expression of vascular endothelial growth factor, basic fibroblast growth factor, and angiogenin immunoreactivity in asthmatic airways and its relationship to angiogenesis. J Allergy Clin Immunol 2001;107:295-301.
43. LEONARDI A, BRUN P, TAVOLATO M, ABATANGELO G, PLEBANI M, SECCHI AG. Growth factors and collagen distribution in vernal keratoconjuctivitis. Invest Ophthalmol Vis Sci 2000;41:4175-4181.
44. HOSHINO M, TAKAHASHI M, AOIKE N. Expression of vascular endothelial growth factor, basic fibroblast growth factor, and angiogenin immunoreactivity in asthmatic airways and its relationship to angiogenesis. J Allergy Clin Immunol 2001;107:295-301.
45. KRAMER MF, RASP G. Nasal polyposis eosinophils and interleukin 5. Allergy 1999;54:669-680.
46. PUXEDDU I, ALIAN A, PILIPONSKY AM, PANET A, LEVI-SCHAFFER F. Modulatory role of human blood eosinophils in angiogenesis: ex vivo and in vitro studies. J Allergy Clin Immunol 2003;111:S211.
47. TEMKIN V, AINGORN H, GOLDSHMIDT O, GLEICH GJ, VLODAVSKY I, LEVI-SCHAFFER F. Heparanase is contained in human peripheral blood eosinophils and its activity is inhibited by eosinophil granule basic proteins. J Allergy Clin Immunol 2003;111:S258.
48. VLODAVSKI I, FRIEDMAN Y. Molecular properties and involvement of heparanase in cancer metastasis and angiogenesis. J Clin Invest 2001;108:341-347.
49. SAMOSZUK M. Eosinophils and human cancer. Histol Histopathol 1997;12: 807-812.
50. RIVOLTINI L, VIGGIANO V, SPINAZZE S, SANTORO A, COLOMBO MP, TAKATSU K et al. In vitro antitumor activity of eosinophils from cancer patients treated with subcutaneous administration of interleukin 2. Int J Cancer 1993;54:8-15.
51. FERNANDEZ-ACENERO MJ, GALINDO-GALLEGO M, SANZ J, ALJAMA A. Prognostic influence of tumor-associated eosinophilic infiltrate in colorectal carcinoma. Cancer 2000;88:1544-1548.
52. ROBERTS RL, BONNIE JA, STIEHM ER. Human eosinophils are more toxic than neutrophils in antibody-independent killing. J Allergy Clin Immunol 1991;87:1105-1115.
53. NATHAN CF, KLEBANOFF SJ. Augmentation of spontaneous macrophage-mediated cytolysis by eosinophil peroxidase. J Exp Med 1982;155:1291-1308.
54. VAN DER VLIET A, EISTRICH JP, HALIWELL B, CROSS CE. Formation of reactive nitrogen species during peroxidase-catalyzed oxidation of nitrite a potential additional mechanism of nitric oxide-dependent toxicity. J Biol Chem 1997;272:7617-7625.
55. + T cells in the antitumor immune response. J Exp Med 1998;188:2357-2368.
56. MATTES J, HULETT M, XIE W, HOGAN S, ROTHENBERG ME, FOSTER P et al. Immunotherapy of cytotoxic T cell-resistant tumors by T helper 2 cells: an eotaxin and STAT 6-dependent process. J Exp Med 2003;197:387-393.
57. RAVETCH JV, LANIER LL. Immune inhibitory receptors. Science 2000;290:84-89.
58. COLONNA M, NAKAJIMA H, NAVARRO F, LOPEZ-BOTET M. A novel family of Ig-like receptors for HLA class I molecules that modulate function of lymphoid and myeloid cells. J Leukoc Biol 1999;66:375-381.
59. COLONNA M. TREMs in the immune system and beyond. Nat Rev Immunol 2003;6:445-453.
60. TEDLA N, BANDERIA-MELO C, TASSINARI P, SLOANE DE, SAMPLASKI M, COSMAN D et al. Activation of human peripheral blood eosinophils through leukocyte immunoglobulin-like receptor 7. Proc Natl Acad Sci USA 2003;100:1174-1179.
61. MUNDAY J, KERR S, NI J, CORNISH AL, ZHANG JQ, NICOLL G et al. Identification characterization and leucocyte expression of siglec-10 a novel human sialic acid-binding receptor. Biochem J 2001;355:489-497.
62. PAUL SP, TAYLOR LS, STANSBURY EK, MCVICAR DW. Myeloid specific human CD33 is an inhibitory receptor with differential ITIM function in recruiting the phosphatases SHP-1 and SHP-2. Blood 96:483-490.
63. NUTKU E, AIZAWA H, HUDSON SH, BOCHNER BS. Ligation of siglec-8: a selective mechanism for induction of human eosinophil apoptosis. Blood 2003;101:5014-5020.
64. MUNITZ A, COLONNA M, LEVI-SCHAFFER F. 2B4 (CD244) is expressed and functional on human peripheral blood eosinophils. J Allergy Clin Immunol 2003;111:S259.
65. PAROLINI S, BOTTINO C, FALCO M, AUGUGLIARO R, GILIANI S, FRANCESCHINI R et al. X-linked lymphoproliferative disease. 2B4 molecules displaying inhibitory rather than activating function are responsible for the inability of natural killer cells to kill Epstein-Barr virus-infected cells. J Exp Med 2000;192:337-346.
66. NAKAJIMA H, COLONNA M. 2B4: an NK cell activating receptor with unique specificity and signal transduction mechanism. Hum Immunol 2000;61:39-43.
67. TANGYE SG, LAZETIC S, WOOLATT E, SUTHERLAND GR, LANIER LL, PHILLIPS JH. Cutting edge: human 2B4, an activating NK cell receptor, recruits the protein tyrosine phosphatase SHP-2 and the adaptor signaling protein SAP. J Immunol 1999;162:6981-6985.
68. KAMATA T, YAMASHITA M, KIMURA M, MURATA K, INAMI M, SHIMIZU C et al. src homology 2 domain-containing tyrosine phosphatase SHP-1 controls the development of allergic airway inflammation. J Clin Invest 2003;111:109-119.