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Volumn 306, Issue 4, 2014, Pages

Ginsenoside Rb1 ameliorates lipopolysaccharide-induced albumin leakage from rat mesenteric venules by intervening in both trans- and paracellular pathway

Author keywords

Caveolin 1; Hyperpermeability; Nuclear factor B; Panax ginseng; Src

Indexed keywords

CAVEOLIN-1; HYPERPERMEABILITY; NUCLEAR FACTOR-ΚB; PANAX GINSENG; SRC;

EID: 84894055013     PISSN: 01931857     EISSN: 15221547     Source Type: Journal    
DOI: 10.1152/ajpgi.00168.2013     Document Type: Article
Times cited : (43)

References (45)
  • 1
    • 0021953687 scopus 로고
    • Enterotoxigenic Escherichia coli infections in newborn calves: A review
    • Acres SD. Enterotoxigenic Escherichia coli infections in newborn calves: a review. J Dairy Sci 68: 229-256, 1985.
    • (1985) J Dairy Sci , vol.68 , pp. 229-256
    • Acres, S.D.1
  • 5
    • 84885434905 scopus 로고    scopus 로고
    • Ginsenoside Rb1 prevents interleukin-1 beta induced inflammation and apoptosis in human articular chondrocytes
    • Cheng W, Wu D, Zuo Q, Wang Z, Fan W. Ginsenoside Rb1 prevents interleukin-1 beta induced inflammation and apoptosis in human articular chondrocytes. Int Orthop 37: 2065-2070, 2013.
    • (2013) Int Orthop , vol.37 , pp. 2065-2070
    • Cheng, W.1    Wu, D.2    Zuo, Q.3    Wang, Z.4    Fan, W.5
  • 8
    • 0029086362 scopus 로고
    • De novo formation of caveolae in lymphocytes by expression of VIP21-caveolin
    • Fra AM, Williamson E, Simons K, Parton RG. De novo formation of caveolae in lymphocytes by expression of VIP21-caveolin. Proc Natl Acad Sci USA 92: 8655-8659, 1995.
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 8655-8659
    • Fra, A.M.1    Williamson, E.2    Simons, K.3    Parton, R.G.4
  • 10
    • 45149123112 scopus 로고    scopus 로고
    • TLR4 signaling is coupled to SRC family kinase activation, tyrosine phosphorylation of zonula adherens proteins, and opening of the paracellular pathway in human lung microvascular endothelia
    • Gong P, Angelini DJ, Yang S, Cross AS, Mann D, Bannerman DD, Vogel SN, Goldblum SE. TLR4 signaling is coupled to SRC family kinase activation, tyrosine phosphorylation of zonula adherens proteins, and opening of the paracellular pathway in human lung microvascular endothelia. J Biol Chem 283: 13437-13449, 2008.
    • (2008) J Biol Chem , vol.283 , pp. 13437-13449
    • Gong, P.1    Angelini, D.J.2    Yang, S.3    Cross, A.S.4    Mann, D.5    Bannerman, D.D.6    Vogel, S.N.7    Goldblum, S.E.8
  • 11
    • 0031888035 scopus 로고    scopus 로고
    • Regulation of caveolin and caveolae by cholesterol in MDCK cells
    • Hailstones D, Sleer LS, Parton RG, Stanley KK. Regulation of caveolin and caveolae by cholesterol in MDCK cells. J Lipid Res 39: 369-379, 1998.
    • (1998) J Lipid Res , vol.39 , pp. 369-379
    • Hailstones, D.1    Sleer, L.S.2    Parton, R.G.3    Stanley, K.K.4
  • 12
    • 58249117785 scopus 로고    scopus 로고
    • Potential of 3, 4-dihydroxy-phenyl lactic acid for ameliorating ischemia-reperfusioninduced microvascular disturbance in rat mesentery
    • Han JY, Horie Y, Fan JY, Sun K, Guo J, Miura S, Hibi T. Potential of 3, 4-dihydroxy-phenyl lactic acid for ameliorating ischemia-reperfusioninduced microvascular disturbance in rat mesentery. Am J Physiol Gastrointest Liver Physiol 296: G36-G44, 2009.
    • (2009) Am J Physiol Gastrointest Liver Physiol , vol.296
    • Han, J.Y.1    Horie, Y.2    Fan, J.Y.3    Sun, K.4    Guo, J.5    Miura, S.6    Hibi, T.7
  • 14
    • 84867820015 scopus 로고    scopus 로고
    • Ginsenoside Rb1 prevents MPP(+)-induced apoptosis in PC12 cells by stimulating estrogen receptors with consequent activation of ERK1/2, Akt and inhibition of SAPK/JNK, p38 MAPK
    • Hashimoto R, Yu J, Koizumi H, Ouchi Y, Okabe T. Ginsenoside Rb1 prevents MPP(+)-induced apoptosis in PC12 cells by stimulating estrogen receptors with consequent activation of ERK1/2, Akt and inhibition of SAPK/JNK, p38 MAPK. Evid Based Complement Alternat Med 2012: 693-717, 2012.
    • (2012) Evid Based Complement Alternat Med , vol.2012 , pp. 693-717
    • Hashimoto, R.1    Yu, J.2    Koizumi, H.3    Ouchi, Y.4    Okabe, T.5
  • 15
    • 48249117901 scopus 로고    scopus 로고
    • Intercellular adhesion molecule-1-dependent neutrophil adhesion to endothelial cells induces caveolae-mediated pulmonary vascular hyperpermeability
    • Hu G, Vogel SM, Schwartz DE, Malik AB, Minshall RD. Intercellular adhesion molecule-1-dependent neutrophil adhesion to endothelial cells induces caveolae-mediated pulmonary vascular hyperpermeability. Circ Res 102: e120-e131, 2008.
    • (2008) Circ Res , vol.102
    • Hu, G.1    Vogel, S.M.2    Schwartz, D.E.3    Malik, A.B.4    Minshall, R.D.5
  • 17
    • 70449535513 scopus 로고    scopus 로고
    • Ginsenoside Rb1 protects against 6-hydroxydopamine-induced oxidative stress by increasing heme oxygenase-1 expression through an estrogen receptor-related PI3K/Akt/Nrf2-dependent pathway in human dopaminergic cells
    • Hwang YP, Jeong HG. Ginsenoside Rb1 protects against 6-hydroxydopamine-induced oxidative stress by increasing heme oxygenase-1 expression through an estrogen receptor-related PI3K/Akt/Nrf2-dependent pathway in human dopaminergic cells. Toxicol Appl Pharmacol 242: 18-28, 2010.
    • (2010) Toxicol Appl Pharmacol , vol.242 , pp. 18-28
    • Hwang, Y.P.1    Jeong, H.G.2
  • 18
    • 79959563146 scopus 로고    scopus 로고
    • Ginsenoside Rb1 and its metabolite compound K inhibit IRAK-1 activation-the key step of inflammation
    • Joh EH, Lee IA, Jung IH, Kim DH. Ginsenoside Rb1 and its metabolite compound K inhibit IRAK-1 activation-the key step of inflammation. Biochem Pharmacol 82: 278-286, 2011.
    • (2011) Biochem Pharmacol , vol.82 , pp. 278-286
    • Joh, E.H.1    Lee, I.A.2    Jung, I.H.3    Kim, D.H.4
  • 19
    • 0036142331 scopus 로고    scopus 로고
    • Matrix metalloproteinase-9 promotes neutrophil migration and alveolar capillary leakage in pancreatitis-associated lung injury in the rat
    • Keck T, Balcom JHt, Fernandez-del Castillo C, Antoniu BA, Warshaw AL. Matrix metalloproteinase-9 promotes neutrophil migration and alveolar capillary leakage in pancreatitis-associated lung injury in the rat. Gastroenterology 122: 188-201, 2002.
    • (2002) Gastroenterology , vol.122 , pp. 188-201
    • Keck, T.1    Balcom, J.H.2    Fernandez-del Castillo, C.3    Antoniu, B.A.4    Warshaw, A.L.5
  • 20
    • 77951697920 scopus 로고    scopus 로고
    • Regulation of endothelial permeability via paracellular and transcellular transport pathways
    • Komarova Y, Malik AB. Regulation of endothelial permeability via paracellular and transcellular transport pathways. Annu Rev Physiol 72: 463-493, 2010.
    • (2010) Annu Rev Physiol , vol.72 , pp. 463-493
    • Komarova, Y.1    Malik, A.B.2
  • 22
    • 77956635947 scopus 로고    scopus 로고
    • Sepsis and endothelial permeability
    • Lee WL, Slutsky AS. Sepsis and endothelial permeability. N Engl J Med 363: 689-691, 2010.
    • (2010) N Engl J Med , vol.363 , pp. 689-691
    • Lee, W.L.1    Slutsky, A.S.2
  • 23
    • 34948887630 scopus 로고    scopus 로고
    • Ginsenoside Rb1 inhibits tube-like structure formation of endothelial cells by regulating pigment epithelium-derived factor through the oestrogen beta receptor
    • Leung KW, Cheung LWT, Pon YL, Wong RNS, Mak NK, Fan TPD, Au SCL, Tombran-Tink J, Wong AST. Ginsenoside Rb1 inhibits tube-like structure formation of endothelial cells by regulating pigment epithelium-derived factor through the oestrogen beta receptor. Br J Pharmacol 152: 207-215, 2007.
    • (2007) Br J Pharmacol , vol.152 , pp. 207-215
    • Leung, K.W.1    Cheung, L.W.T.2    Pon, Y.L.3    Wong, R.N.S.4    Mak, N.K.5    Fan, T.P.D.6    Au, S.C.L.7    Tombran-Tink, J.8    Wong, A.S.T.9
  • 24
    • 84863230646 scopus 로고    scopus 로고
    • Matrix metalloproteinase-2-mediated occludin degradation and caveolin-1-mediated claudin-5 redistribution contribute to blood-brain barrier damage in early ischemic stroke stage
    • Liu J, Jin X, Liu KJ, Liu W. Matrix metalloproteinase-2-mediated occludin degradation and caveolin-1-mediated claudin-5 redistribution contribute to blood-brain barrier damage in early ischemic stroke stage. J Neurosci 32: 3044-3057, 2012.
    • (2012) J Neurosci , vol.32 , pp. 3044-3057
    • Liu, J.1    Jin, X.2    Liu, K.J.3    Liu, W.4
  • 26
    • 0028860550 scopus 로고
    • Inflammatory cytokines in the BAL of patients with ARDS. Persistent elevation over time predicts poor outcome
    • Meduri GU, Kohler G, Headley S, Tolley E, Stentz F, Postlethwaite A. Inflammatory cytokines in the BAL of patients with ARDS. Persistent elevation over time predicts poor outcome. Chest 108: 1303-1314, 1995.
    • (1995) Chest , vol.108 , pp. 1303-1314
    • Meduri, G.U.1    Kohler, G.2    Headley, S.3    Tolley, E.4    Stentz, F.5    Postlethwaite, A.6
  • 27
    • 33644839612 scopus 로고    scopus 로고
    • Signaling mechanisms regulating endothelial permeability
    • Mehta D, Malik AB. Signaling mechanisms regulating endothelial permeability. Physiol Rev 86: 279-367, 2006.
    • (2006) Physiol Rev , vol.86 , pp. 279-367
    • Mehta, D.1    Malik, A.B.2
  • 28
    • 0034605039 scopus 로고    scopus 로고
    • Endothelial cell-surface gp60 activates vesicle formation and trafficking via G(i)-coupled Src kinase signaling pathway
    • Minshall RD, Tiruppathi C, Vogel SM, Niles WD, Gilchrist A, Hamm HE, Malik AB. Endothelial cell-surface gp60 activates vesicle formation and trafficking via G(i)-coupled Src kinase signaling pathway. J Cell Biol 150: 1057-1070, 2000.
    • (2000) J Cell Biol , vol.150 , pp. 1057-1070
    • Minshall, R.D.1    Tiruppathi, C.2    Vogel, S.M.3    Niles, W.D.4    Gilchrist, A.5    Hamm, H.E.6    Malik, A.B.7
  • 33
    • 33750047495 scopus 로고    scopus 로고
    • Management of sepsis
    • Russell JA. Management of sepsis. N Engl J Med 355: 1699-1713, 2006.
    • (2006) N Engl J Med , vol.355 , pp. 1699-1713
    • Russell, J.A.1
  • 34
    • 0035965995 scopus 로고    scopus 로고
    • Caveolae-deficient Endothelial Cells Show Defects in the Uptake and Transport of Albumin in Vivo
    • Schubert W, Frank PG, Razani B, Park DS, Chow CW, Lisanti MP. Caveolae-deficient Endothelial Cells Show Defects in the Uptake and Transport of Albumin in Vivo. J Biol Chem 276: 48619-48622, 2001.
    • (2001) J Biol Chem , vol.276 , pp. 48619-48622
    • Schubert, W.1    Frank, P.G.2    Razani, B.3    Park, D.S.4    Chow, C.W.5    Lisanti, M.P.6
  • 36
    • 34547096543 scopus 로고    scopus 로고
    • Lipopolysaccharide disrupts tight junctions in cholangiocyte monolayers by a c-Src-, TLR4-, and LBP-dependent mechanism
    • Sheth P, Delos Santos N, Seth A, LaRusso NF, Rao RK. Lipopolysaccharide disrupts tight junctions in cholangiocyte monolayers by a c-Src-, TLR4-, and LBP-dependent mechanism. Am J Physiol Gastrointest Liver Physiol 293: G308-G318, 2007.
    • (2007) Am J Physiol Gastrointest Liver Physiol , vol.293
    • Sheth, P.1    Delos Santos, N.2    Seth, A.3    LaRusso, N.F.4    Rao, R.K.5
  • 38
    • 0036787474 scopus 로고    scopus 로고
    • Chronic stress induces mast cell-dependent bacterial adherence and initiates mucosal inflammation in rat intestine
    • Söderholm JD, Yang PC, Ceponis P, Vohra A, Riddell R, Sherman PM, Perdue MH. Chronic stress induces mast cell-dependent bacterial adherence and initiates mucosal inflammation in rat intestine. Gastroenterology 123: 1099-1108, 2002.
    • (2002) Gastroenterology , vol.123 , pp. 1099-1108
    • Söderholm, J.D.1    Yang, P.C.2    Ceponis, P.3    Vohra, A.4    Riddell, R.5    Sherman, P.M.6    Perdue, M.H.7
  • 39
    • 34547405823 scopus 로고    scopus 로고
    • Protective effects of ginsenoside Rb1, ginsenoside Rg1, and notoginsenoside R1 on lipopolysaccharide-induced microcirculatory disturbance in rat mesentery
    • Sun K, Wang CS, Guo J, Horie Y, Fang SP, Wang F, Liu YY, Liu LY, Yang JY, Fan JY, Han JY. Protective effects of ginsenoside Rb1, ginsenoside Rg1, and notoginsenoside R1 on lipopolysaccharide-induced microcirculatory disturbance in rat mesentery. Life Sci 81: 509-518, 2007.
    • (2007) Life Sci , vol.81 , pp. 509-518
    • Sun, K.1    Wang, C.S.2    Guo, J.3    Horie, Y.4    Fang, S.P.5    Wang, F.6    Liu, Y.Y.7    Liu, L.Y.8    Yang, J.Y.9    Fan, J.Y.10    Han, J.Y.11
  • 40
    • 70349705635 scopus 로고    scopus 로고
    • Phosphorylation of caveolin-1 regulates oxidant-induced pulmonary vascular permeability via paracellular and transcellular pathways
    • Sun Y, Hu G, Zhang X, Minshall RD. Phosphorylation of caveolin-1 regulates oxidant-induced pulmonary vascular permeability via paracellular and transcellular pathways. Circ Res 105: 676-685, 2009.
    • (2009) Circ Res , vol.105 , pp. 676-685
    • Sun, Y.1    Hu, G.2    Zhang, X.3    Minshall, R.D.4
  • 41
    • 42949158943 scopus 로고    scopus 로고
    • Role of NF-kappaB-dependent caveolin-1 expression in the mechanism of increased endothelial permeability induced by lipopolysaccharide
    • Tiruppathi C, Shimizu J, Miyawaki-Shimizu K, Vogel SM, Bair AM, Minshall RD, Predescu D, Malik AB. Role of NF-kappaB-dependent caveolin-1 expression in the mechanism of increased endothelial permeability induced by lipopolysaccharide. J Biol Chem 283: 4210-4218, 2008.
    • (2008) J Biol Chem , vol.283 , pp. 4210-4218
    • Tiruppathi, C.1    Shimizu, J.2    Miyawaki-Shimizu, K.3    Vogel, S.M.4    Bair, A.M.5    Minshall, R.D.6    Predescu, D.7    Malik, A.B.8
  • 42
    • 0035896560 scopus 로고    scopus 로고
    • Cellular stress induces the tyrosine phosphorylation of caveolin-1 (Tyr(14) via activation of p38 mitogen-activated protein kinase and c-Src kinase. Evidence for caveolae, the actin cytoskeleton, and focal adhesions as mechanical sensors of osmotic stress
    • Volonte D, Galbiati F, Pestell RG, Lisanti MP. Cellular stress induces the tyrosine phosphorylation of caveolin-1 (Tyr(14) via activation of p38 mitogen-activated protein kinase and c-Src kinase. Evidence for caveolae, the actin cytoskeleton, and focal adhesions as mechanical sensors of osmotic stress. J Biol Chem 276: 8094-8103, 2001.
    • (2001) J Biol Chem , vol.276 , pp. 8094-8103
    • Volonte, D.1    Galbiati, F.2    Pestell, R.G.3    Lisanti, M.P.4
  • 43
    • 33845982523 scopus 로고    scopus 로고
    • Signaling pathway of nitric oxide production induced by ginsenoside Rb1 in human aortic endothelial cells: A possible involvement of androgen receptor
    • Yu J, Eto M, Akishita M, Kaneko A, Ouchi Y, Okabe T. Signaling pathway of nitric oxide production induced by ginsenoside Rb1 in human aortic endothelial cells: a possible involvement of androgen receptor. Biochem Biophys Res Commun 353: 764-769, 2007.
    • (2007) Biochem Biophys Res Commun , vol.353 , pp. 764-769
    • Yu, J.1    Eto, M.2    Akishita, M.3    Kaneko, A.4    Ouchi, Y.5    Okabe, T.6


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