Walnut-enriched diet reduces fasting non-hdl-cholesterol and apolipoprotein b in healthy caucasian subjects: A randomized controlled cross-over clinical trial

Metabolism: Clinical and Experimental

Volumn 63, Issue 3, 2014, Pages 382-391

  Wu, Liya ^a   Piotrowski, Katja ^a   Rau, Tiina ^a   Waldmann, Elisa ^a   Broedl, Uli C ^a   Demmelmair, Hans ^a   Koletzko, Berthold ^a   Stark, Renee G ^b   Nagel, Jutta M ^a   Mantzoros, Christos S ^c   Parhofer, Klaus G ^a  

^a LUDWIG MAXIMILIANS UNIVERSITY   (Germany)

^b INSTITUTE OF EPIDEMIOLOGY   (Germany)

^c BETH ISRAEL DEACONESS MEDICAL CENTER   (United States)

Author keywords

Endothelial function; Glucose; Lipids; Nuts; Peripheral artery tonometry

Indexed keywords

ENDOTHELIAL FUNCTION; GLUCOSE; LIPIDS; NUTS; PERIPHERAL ARTERY TONOMETRY;

ADIPOKINES; APOLIPOPROTEINS B; C-REACTIVE PROTEIN; CHOLESTEROL, HDL; CHOLESTEROL, LDL; CHOLESTEROL, VLDL; CHYLOMICRONS; CROSS-OVER STUDIES; DIET; ENDOTHELIUM; EUROPEAN CONTINENTAL ANCESTRY GROUP; FASTING; FEMALE; GLUCOSE; HEMOGLOBIN A, GLYCOSYLATED; HUMANS; INFLAMMATION; INSULIN; JUGLANS; LIPID METABOLISM; LIPOPROTEINS, VLDL; MALE; MIDDLE AGED; POSTPRANDIAL PERIOD; PROSPECTIVE STUDIES; TRIGLYCERIDES;

EID: 84894030288     PISSN: 00260495     EISSN: 15328600     Source Type: Journal    
DOI: 10.1016/j.metabol.2013.11.005     Document Type: Article

References (55)

1. J.H. Kelly Jr., and J. Sabate Nuts and coronary heart disease: an epidemiological perspective Br J Nutr 96 Suppl. 2 2006 S61 S67
2. L. Tarantino Qualified health claims: letter of enforcement discretion - walnuts and coronary heart disease (docket no. 02P-0292) Mar. 9 2004 [Assessed at http://www.fda.gov/Food/IngredientsPackagingLabeling/LabelingNutrition/ ucm072910.htm on 30 September 2013]
3. US Department of Agriculture, and Agricultural Research Service USDA national nutrient database for standard reference Release 24 2011 [assessed at http://www.ars.usda.gov/ba/bhnrc/ndl on 15 May 2013]
4. K.S. Robbins, E.C. Shin, and R.L. Shewfelt et al. Update on the healthful lipid constituents of commercially important tree nuts J Agric Food Chem 59 22 2011 12083 12092
5. G. Zhao, T.D. Etherton, and K.R. Martin et al. Dietary alpha-linolenic acid reduces inflammatory and lipid cardiovascular risk factors in hypercholesterolemic men and women J Nutr 134 11 2004 2991 2997
6. A. Sala-Vila, M. Cofan, and I. Nunez et al. Carotid and femoral plaque burden is inversely associated with the alpha-linolenic acid proportion of serum phospholipids in Spanish subjects with primary dyslipidemia Atherosclerosis 214 1 2011 209 214
7. A. Pan, M. Chen, and R. Chowdhury et al. alpha-Linolenic acid and risk of cardiovascular disease: a systematic review and meta-analysis Am J Clin Nutr 96 6 2012 1262 1273
8. W.S. Harris n-3 fatty acids and serum lipoproteins: human studies Am J Clin Nutr 65 5 Suppl 1997 645S 654S
9. E. Ros Health benefits of nut consumption Nutrients 2 7 2010 652 682
10. D.K. Banel, and F.B. Hu Effects of walnut consumption on blood lipids and other cardiovascular risk factors: a meta-analysis and systematic review Am J Clin Nutr 90 1 2009 56 63
11. E. Ros, I. Nunez, and A. Perez-Heras et al. A walnut diet improves endothelial function in hypercholesterolemic subjects: a randomized crossover trial Circulation 109 13 2004 1609 1614
12. B. Cortes, I. Nunez, and M. Cofan et al. Acute effects of high-fat meals enriched with walnuts or olive oil on postprandial endothelial function J Am Coll Cardiol 48 8 2006 1666 1671
13. Y. Ma, V.Y. Njike, and J. Millet et al. Effects of walnut consumption on endothelial function in type 2 diabetic subjects: a randomized controlled crossover trial Diabetes Care 33 2 2010 227 232
14. A. Pan, Q. Sun, and J.E. Manson et al. Walnut consumption is associated with lower risk of type 2 diabetes in women J Nutr 143 4 2013 512 518
15. L.C. Tapsell, L.J. Gillen, and C.S. Patch et al. Including walnuts in a low-fat/modified-fat diet improves HDL cholesterol-to-total cholesterol ratios in patients with type 2 diabetes Diabetes Care 27 12 2004 2777 2783
16. J. Mukuddem-Petersen, W. Stonehouse Oosthuizen, and J.C. Jerling et al. Effects of a high walnut and high cashew nut diet on selected markers of the metabolic syndrome: a controlled feeding trial Br J Nutr 97 6 2007 1144 1153
17. A.M. Brennan, L.L. Sweeney, and X. Liu et al. Walnut consumption increases satiation but has no effect on insulin resistance or the metabolic profile over a 4-day period Obesity (Silver Spring) 18 6 2010 1176 1182
18. P. Casas-Agustench, P. Lopez-Uriarte, and M. Bullo et al. Effects of one serving of mixed nuts on serum lipids, insulin resistance and inflammatory markers in patients with the metabolic syndrome Nutr Metab Cardiovasc Dis 21 2 2011 126 135
19. S. Kalgaonkar, R.U. Almario, and D. Gurusinghe et al. Differential effects of walnuts vs almonds on improving metabolic and endocrine parameters in PCOS Eur J Clin Nutr 65 3 2011 386 393
20. J. Sabate, G.E. Fraser, and K. Burke et al. Effects of walnuts on serum lipid levels and blood pressure in normal men N Engl J Med 328 9 1993 603 607
21. M. Iwamoto, K. Imaizumi, and M. Sato et al. Serum lipid profiles in Japanese women and men during consumption of walnuts Eur J Clin Nutr 56 7 2002 629 637
22. S. Torabian, E. Haddad, and Z. Cordero-MacIntyre et al. Long-term walnut supplementation without dietary advice induces favorable serum lipid changes in free-living individuals Eur J Clin Nutr 64 3 2010 274 279
23. J.N. Din, S.M. Aftab, and A.W. Jubb et al. Effect of moderate walnut consumption on lipid profile, arterial stiffness and platelet activation in humans Eur J Clin Nutr 65 2 2011 234 239
24. B.G. Nordestgaard, M. Benn, and P. Schnohr et al. Nonfasting triglycerides and risk of myocardial infarction, ischemic heart disease, and death in men and women JAMA 298 3 2007 299 308
25. T.S. Temelkova-Kurktschiev, C. Koehler, and E. Henkel et al. Postchallenge plasma glucose and glycemic spikes are more strongly associated with atherosclerosis than fasting glucose or HbA1c level Diabetes Care 23 12 2000 1830 1834
26. M.E. Otto, A. Svatikova, and R.B. Barretto et al. Early morning attenuation of endothelial function in healthy humans Circulation 109 21 2004 2507 2510
27. A.C. Skulas-Ray, P.M. Kris-Etherton, and W.S. Harris et al. Dose-response effects of omega-3 fatty acids on triglycerides, inflammation, and endothelial function in healthy persons with moderate hypertriglyceridemia Am J Clin Nutr 93 2 2011 243 252
28. C. Glaser, H. Demmelmair, and B. Koletzko High-throughput analysis of fatty acid composition of plasma glycerophospholipids J Lipid Res 51 1 2010 216 221
29. K.G. Parhofer, P.H. Barrett, and P. Schwandt Atorvastatin improves postprandial lipoprotein metabolism in normolipidemlic subjects J Clin Endocrinol Metab 85 11 2000 4224 4230
30. D.R. Matthews, J.P. Hosker, and A.S. Rudenski et al. Homeostasis model assessment: insulin resistance and beta-cell function from fasting plasma glucose and insulin concentrations in man Diabetologia 28 7 1985 412 419
31. A. Katz, S.S. Nambi, and K. Mather et al. Quantitative insulin sensitivity check index: a simple, accurate method for assessing insulin sensitivity in humans J Clin Endocrinol Metab 85 7 2000 2402 2410
32. E. Ingelsson, E.J. Schaefer, and J.H. Contois et al. Clinical utility of different lipid measures for prediction of coronary heart disease in men and women JAMA 298 7 2007 776 785
33. J. Liu, C. Sempos, and R.P. Donahue et al. Joint distribution of non-HDL and LDL cholesterol and coronary heart disease risk prediction among individuals with and without diabetes Diabetes Care 28 8 2005 1916 1921
34. J. Liu, C.T. Sempos, and R.P. Donahue et al. Non-high-density lipoprotein and very-low-density lipoprotein cholesterol and their risk predictive values in coronary heart disease Am J Cardiol 98 10 2006 1363 1368
35. A. Varbo, M. Benn, and A. Tybjaerg-Hansen et al. Remnant cholesterol as a causal risk factor for ischemic heart disease J Am Coll Cardiol 61 4 2013 427 436
36. J.G. Robinson, S. Wang, and B.J. Smith et al. Meta-analysis of the relationship between non-high-density lipoprotein cholesterol reduction and coronary heart disease risk J Am Coll Cardiol 53 4 2009 316 322
37. R. Estruch, E. Ros, and J. Salas-Salvado et al. Primary prevention of cardiovascular disease with a Mediterranean diet N Engl J Med 368 14 2013 1279 1290
38. R. Clarke, C. Frost, and R. Collins et al. Dietary lipids and blood cholesterol: quantitative meta-analysis of metabolic ward studies BMJ 314 7074 1997 112 117
39. N.R. Damasceno, A. Perez-Heras, and M. Serra et al. Crossover study of diets enriched with virgin olive oil, walnuts or almonds. Effects on lipids and other cardiovascular risk markers Nutr Metab Cardiovasc Dis 21 Suppl. 1 2011 S14 S20
40. J. Sabate, K. Oda, and E. Ros Nut consumption and blood lipid levels: a pooled analysis of 25 intervention trials Arch Intern Med 170 9 2010 821 827
41. R.U. Almario, V. Vonghavaravat, and R. Wong et al. Effects of walnut consumption on plasma fatty acids and lipoproteins in combined hyperlipidemia Am J Clin Nutr 74 1 2001 72 79
42. D. Zambon, J. Sabate, and S. Munoz et al. Substituting walnuts for monounsaturated fat improves the serum lipid profile of hypercholesterolemic men and women. A randomized crossover trial Ann Intern Med 132 7 2000 538 546
43. M. Abbey, M. Noakes, and G.B. Belling et al. Partial replacement of saturated fatty acids with almonds or walnuts lowers total plasma cholesterol and low-density-lipoprotein cholesterol Am J Clin Nutr 59 5 1994 995 999
44. S. Munoz, M. Merlos, and D. Zambon et al. Walnut-enriched diet increases the association of LDL from hypercholesterolemic men with human HepG2 cells J Lipid Res 42 12 2001 2069 2076
45. S.C. Li, Y.H. Liu, and J.F. Liu et al. Almond consumption improved glycemic control and lipid profiles in patients with type 2 diabetes mellitus Metabolism 60 4 2011 474 479
46. K.N. Aronis, M.T. Vamvini, and J.P. Chamberland et al. Short-term walnut consumption increases circulating total adiponectin and apolipoprotein A concentrations, but does not affect markers of inflammation or vascular injury in obese humans with the metabolic syndrome: data from a double-blinded, randomized, placebo-controlled study Metabolism 61 4 2012 577 582
47. K. Okada, H. Yagyu, and K. Kotani et al. Effects of miglitol versus sitagliptin on postprandial glucose and lipoprotein metabolism in patients with type 2 diabetes mellitus Endocr J 60 7 2013 913 922
48. E. Waldmann, T.P. Huttl, and B. Goke et al. Effect of sleeve gastrectomy on postprandial lipoprotein metabolism in morbidly obese patients Lipids Health Dis 12 2013 82
49. P. Lopez-Uriarte, R. Nogues, and G. Saez et al. Effect of nut consumption on oxidative stress and the endothelial function in metabolic syndrome Clin Nutr 29 3 2010 373 380
50. S.E. Berry, E.A. Tydeman, and H.B. Lewis et al. Manipulation of lipid bioaccessibility of almond seeds influences postprandial lipemia in healthy human subjects Am J Clin Nutr 88 4 2008 922 929
51. C.E. Berryman, J.A. Grieger, and S.G. West et al. Acute consumption of walnuts and walnut components differentially affect postprandial lipemia, endothelial function, oxidative stress, and cholesterol efflux in humans with mild hypercholesterolemia J Nutr 143 6 2013 788 794
52. P. Poredos, and M.K. Jezovnik Testing endothelial function and its clinical relevance J Atheroscler Thromb 20 1 2013 1 8
53. A. Nohria, M. Gerhard-Herman, and M.A. Creager et al. Role of nitric oxide in the regulation of digital pulse volume amplitude in humans J Appl Physiol (1985) 101 2 2006 545 548
54. D.H. Thijssen, M.A. Black, and K.E. Pyke et al. Assessment of flow-mediated dilation in humans: a methodological and physiological guideline Am J Physiol Heart Circ Physiol 300 1 2011 H2 H12
55. M. Dhindsa, S.M. Sommerlad, and A.E. DeVan et al. Interrelationships among noninvasive measures of postischemic macro- and microvascular reactivity J Appl Physiol (1985) 105 2 2008 427 432