Role of nitric oxide in the regulation of digital pulse volume amplitude in humans

Journal of Applied Physiology

Volumn 101, Issue 2, 2006, Pages 545-548

  Nohria, Anj ^a   Gerhard Herman, Marie ^a   Creager, Mark A ^a   Hurley, Shauna ^a   Mitra, Debi ^a   Ganz, Peter ^a  

^a BRIGHAM AND WOMEN S HOSPITAL   (United States)

Author keywords

Endothelium; Reactive hyperemia; Vasodilation

Indexed keywords

N(G) NITROARGININE METHYL ESTER; NITRIC OXIDE; PHENYLEPHRINE; SODIUM CHLORIDE;

ADULT; ARTICLE; BIOAVAILABILITY; CONTROLLED STUDY; DRUG EFFECT; FEMALE; HUMAN; HUMAN EXPERIMENT; HYPEREMIA; MALE; NORMAL HUMAN; PRIORITY JOURNAL; PULSE RATE; STATISTICAL ANALYSIS; TONOMETRY; VASCULARIZATION; VASOCONSTRICTION; VASODILATATION;

ADULT; BLOOD VOLUME; ENZYME INHIBITORS; FEMALE; FINGERS; HUMANS; HYPEREMIA; MALE; NG-NITROARGININE METHYL ESTER; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; PHENYLEPHRINE; PULSATILE FLOW; REGIONAL BLOOD FLOW; SODIUM CHLORIDE; VASOCONSTRICTOR AGENTS;

EID: 33746780701     PISSN: 87507587     EISSN: 15221601     Source Type: Journal    
DOI: 10.1152/japplphysiol.01285.2005     Document Type: Article

References (21)

1. Andrawis N, Jones DS, and Abernethy DR. Aging is associated with endothelial dysfunction in the human forearm vasculature. J Am Geriatr Soc 48: 193-198, 2000.
2. Behrendt D and Ganz P. Endothelial function. From vascular biology to clinical applications. Am J Cardiol 90: 40L-48L, 2002.
3. Bonetti PO, Barsness GW, Keelan PC, Schnell TI, Pumper GM, Kuvin JT, Schnall RP, Holmes DR, Higano ST, and Lerman A. Enhanced external counterpulsation improves endothelial function in patients with symptomatic coronary artery disease. J Am Coll Cardiol 41: 1761-1768, 2003.
4. Bonetti PO, Lerman LO, and Lerman A. Endothelial dysfunction: a marker of atherosclerotic risk. Arterioscler Thromb Vasc Biol 23: 168-175, 2003.
5. Bonetti PO, Pumper GM, Higano ST, Holmes DR Jr, Kuvin JT, and Lerman A. Noninvasive identification of patients with early coronary atherosclerosis by assessment of digital reactive hyperemia. J Am Coll Cardiol 44: 2137-2141, 2004.
6. Coffman JD. Effects of endothelium-derived nitric oxide on skin and digital blood flow in humans. Am J Physiol Heart Circ Physiol 267: H2087-H2090, 1994.
7. Cremona G, Higenbottam TW, Bower EA, Wood AM, and Stewart S. Hemodynamic effects of basal and stimulated release of endogenous nitric oxide in isolated human lungs. Circulation 100: 1316-1321, 1999.
8. Furchgott RF and Zawadzki JV. The obligatory role of endothelial cells in the relaxation of arterial smooth muscle by acetylcholine. Nature 288: 373-376, 1980.
9. Ganz P and Vita JA. Testing endothelial vasomotor function: nitric oxide, a multipotent molecule. Circulation 108: 2049-2053, 2003.
10. Hamilton CA, Williams R, Pathi V, Berg G, McArthur K, McPhaden AR, Reid JL, and Dominiczak AF. Pharmacological characterisation of endothelium-dependent relaxation in human radial artery: comparison with internal thoracic artery. Cardiovasc Res 42: 214-223, 1999.
11. Hedblad B, Ogren M, Janzon L, Isacsson SO, and Lindell SE. Low pulse-wave amplitude during reactive leg hyperaemia: an independent, early marker for ischaemic heart disease and death. Results from the 21-year follow-up of the prospective cohort study 'Men born in 1914', Malmo, Sweden. J Intern Med 236: 161-168, 1994.
12. Joannides R, Haefeli WE, Linder L, Richard V, Bakkali EH, Thuillez C, and Luscher TF. Nitric oxide is responsible for flow-dependent dilatation of human peripheral conduit arteries in vivo. Circulation 91: 1314-1319, 1995.
13. Kinlay S, Creager MA, Fukumoto M, Hikita H, Fang JC, Selwyn AP, and Ganz P. Endothelium-derived nitric oxide regulates arterial elasticity in human arteries in vivo. Hypertension 38: 1049-1053, 2001.
14. Kuvin JT, Patel AR, Sliney KA, Pandian NG, Sheffy J, Schnall RP, Karas RH, and Udelson JE. Assessment of peripheral vascular endothelial function with finger arterial pulse wave amplitude. Am Heart J 146: 168-174, 2003.
15. Lavie P, Schnall RP, Sheffy J, and Shlitner A. Peripheral vasoconstriction during REM sleep detected by a new plethysmographic method (Letter). Nat Med 6: 606, 2000.
16. Lieberman EH, Gerhard MD, Uehata A, Selwyn AP, Ganz P, Yeung AC, and Creager MA. Flow-induced vasodilation of the human brachial artery is impaired in patients <40 years of age with coronary artery disease. Am J Cardiol 78: 1210-1214, 1996.
17. Noon JP, Haynes WG, Webb DJ, and Shore AC. Local inhibition of nitric oxide generation in man reduces blood flow in finger pulp but not in hand dorsum skin. J Physiol 490: 501-508, 1996.
18. Rozanski A, Qureshi E, Bauman M, Reed G, Pillar G, and Diamond GA. Peripheral arterial responses to treadmill exercise among healthy subjects and atherosclerotic patients. Circulation 103: 2084-2089, 2001.
19. Tawakol A, Omland T, and Creager MA. Direct effect of ethanol on human vascular function. Am J Physiol Heart Circ Physiol 286: H2468-H2473, 2004.
20. Verma S, Buchanan MR, and Anderson TJ. Endothelial function testing as a biomarker of vascular disease. Circulation 108: 2054-2059, 2003.
21. G-nitro-L-arginine inhibit endothelium-dependent relaxations in human isolated omental arteries. J Pharm Pharmacol 43: 869-870, 1991.