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Volumn 232, Issue 4, 2014, Pages 415-427

MicroRNA-30b functions as a tumour suppressor in human colorectal cancer by targeting KRAS, PIK3CD and BCL2

Author keywords

apoptosis; BCL2; colorectal cancer; KRAS; miR 30b; PIK3CD; proliferation

Indexed keywords

MICRORNA; MICRORNA 30B; UNCLASSIFIED DRUG;

EID: 84893839105     PISSN: 00223417     EISSN: 10969896     Source Type: Journal    
DOI: 10.1002/path.4309     Document Type: Article
Times cited : (140)

References (58)
  • 2
    • 79953272159 scopus 로고    scopus 로고
    • Genetics, cytogenetics, and epigenetics of colorectal cancer
    • 2011: 792362
    • Migliore L, Migheli F, Spisni R, et al., Genetics, cytogenetics, and epigenetics of colorectal cancer. J Biomed Biotechnol 2011; 2011: 792362.
    • (2011) J Biomed Biotechnol
    • Migliore, L.1    Migheli, F.2    Spisni, R.3
  • 3
    • 0025312728 scopus 로고
    • A genetic model for colorectal tumorigenesis
    • Fearon ER, Vogelstein B,. A genetic model for colorectal tumorigenesis. Cell 1990; 61: 759-767.
    • (1990) Cell , vol.61 , pp. 759-767
    • Fearon, E.R.1    Vogelstein, B.2
  • 6
    • 38849147752 scopus 로고    scopus 로고
    • Ral GTPases and cancer: Linchpin support of the tumorigenic platform
    • DOI 10.1038/nrc2296, PII NRC2296
    • Bodemann BO, White MA,. Ral GTPases and cancer: linchpin support of the tumorigenic platform. Nat Rev Cancer 2008; 8: 133-140. (Pubitemid 351187648)
    • (2008) Nature Reviews Cancer , vol.8 , Issue.2 , pp. 133-140
    • Bodemann, B.O.1    White, M.A.2
  • 7
    • 33947594129 scopus 로고    scopus 로고
    • Hyperactive Ras in developmental disorders and cancer
    • DOI 10.1038/nrc2109, PII NRC2109
    • Schubbert S, Shannon K, Bollag G,. Hyperactive Ras in developmental disorders and cancer. Nat Rev Cancer 2007; 7: 295-308. (Pubitemid 46480970)
    • (2007) Nature Reviews Cancer , vol.7 , Issue.4 , pp. 295-308
    • Schubbert, S.1    Shannon, K.2    Bollag, G.3
  • 8
    • 84884656400 scopus 로고    scopus 로고
    • MicroRNA in colorectal cancer: New perspectives for diagnosis, prognosis and treatment
    • Bonfrate L, Altomare DF, Di Lena M, et al., MicroRNA in colorectal cancer: new perspectives for diagnosis, prognosis and treatment. J Gastrointest Liver Dis 2013; 22: 311-320.
    • (2013) J Gastrointest Liver Dis , vol.22 , pp. 311-320
    • Bonfrate, L.1    Altomare, D.F.2    Di Lena, M.3
  • 9
    • 84874216566 scopus 로고    scopus 로고
    • MicroRNAs as novel biomarkers in colorectal cancer
    • 2012
    • Hrasovec S, Glavac D,. MicroRNAs as novel biomarkers in colorectal cancer. Front Genet 2012; 3: 180.
    • Front Genet , vol.3 , pp. 180
    • Hrasovec, S.1    Glavac, D.2
  • 10
    • 58249088751 scopus 로고    scopus 로고
    • MicroRNAs: Target recognition and regulatory functions
    • Bartel DP,. MicroRNAs: target recognition and regulatory functions. Cell 2009; 136: 215-233.
    • (2009) Cell , vol.136 , pp. 215-233
    • Bartel, D.P.1
  • 11
    • 71049136170 scopus 로고    scopus 로고
    • MicroRNAs in colorectal cancer: Translation of molecular biology into clinical application
    • Slaby O, Svoboda M, Michalek J, et al., MicroRNAs in colorectal cancer: translation of molecular biology into clinical application. Mol Cancer 2009; 8: 102.
    • (2009) Mol Cancer , vol.8 , pp. 102
    • Slaby, O.1    Svoboda, M.2    Michalek, J.3
  • 12
    • 84873621958 scopus 로고    scopus 로고
    • MiR-21 regulates biological behavior through the PTEN/PI-3 K/Akt signaling pathway in human colorectal cancer cells
    • Xiong B, Cheng Y, Ma L, et al., MiR-21 regulates biological behavior through the PTEN/PI-3 K/Akt signaling pathway in human colorectal cancer cells. Int J Oncol 2013; 42: 219-228.
    • (2013) Int J Oncol , vol.42 , pp. 219-228
    • Xiong, B.1    Cheng, Y.2    Ma, L.3
  • 13
    • 41749113108 scopus 로고    scopus 로고
    • MicroRNA-21 (miR-21) post-transcriptionally downregulates tumor suppressor Pdcd4 and stimulates invasion, intravasation and metastasis in colorectal cancer
    • DOI 10.1038/sj.onc.1210856, PII 1210856
    • Asangani IA, Rasheed SA, Nikolova DA, et al., MicroRNA-21 (miR-21) post-transcriptionally downregulates tumor suppressor Pdcd4 and stimulates invasion, intravasation and metastasis in colorectal cancer. Oncogene 2008; 27: 2128-2136. (Pubitemid 351485639)
    • (2008) Oncogene , vol.27 , Issue.15 , pp. 2128-2136
    • Asangani, I.A.1    Rasheed, S.A.K.2    Nikolova, D.A.3    Leupold, J.H.4    Colburn, N.H.5    Post, S.6    Allgayer, H.7
  • 14
    • 84863891322 scopus 로고    scopus 로고
    • MiR-103/107 promote metastasis of colorectal cancer by targeting the metastasis suppressors DAPK and KLF4
    • Chen HY, Lin YM, Chung HC, et al., miR-103/107 promote metastasis of colorectal cancer by targeting the metastasis suppressors DAPK and KLF4. Cancer Res 2012; 72: 3631-3641.
    • (2012) Cancer Res , vol.72 , pp. 3631-3641
    • Chen, H.Y.1    Lin, Y.M.2    Chung, H.C.3
  • 15
    • 84874812950 scopus 로고    scopus 로고
    • MiR-30a suppresses cell migration and invasion through downregulation of PIK3CD in colorectal carcinoma
    • Zhong M, Bian Z, Wu Z,. miR-30a suppresses cell migration and invasion through downregulation of PIK3CD in colorectal carcinoma. Cell Physiol Biochem 2013; 31: 209-218.
    • (2013) Cell Physiol Biochem , vol.31 , pp. 209-218
    • Zhong, M.1    Bian, Z.2    Wu, Z.3
  • 16
    • 84859560897 scopus 로고    scopus 로고
    • MiR-30a-5p suppresses tumor growth in colon carcinoma by targeting DTL
    • Baraniskin A, Birkenkamp-Demtroder K, Maghnouj A, et al., MiR-30a-5p suppresses tumor growth in colon carcinoma by targeting DTL. Carcinogenesis 2012; 33: 732-739.
    • (2012) Carcinogenesis , vol.33 , pp. 732-739
    • Baraniskin, A.1    Birkenkamp-Demtroder, K.2    Maghnouj, A.3
  • 17
    • 84862219230 scopus 로고    scopus 로고
    • Deregulated miRNAs in hereditary breast cancer revealed a role for miR-30c in regulating KRAS oncogene
    • Tanic M, Yanowsky K, Rodriguez-Antona C, et al., Deregulated miRNAs in hereditary breast cancer revealed a role for miR-30c in regulating KRAS oncogene. PLoS One 2012; 7: e38847.
    • (2012) PLoS One , vol.7
    • Tanic, M.1    Yanowsky, K.2    Rodriguez-Antona, C.3
  • 18
    • 84877138291 scopus 로고    scopus 로고
    • MicroRNA-384-5p regulates ischemia-induced cardioprotection by targeting phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit-δ (PI3K p110δ)
    • Bao Y, Lin C, Ren J, et al., MicroRNA-384-5p regulates ischemia-induced cardioprotection by targeting phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit-δ (PI3K p110δ). Apoptosis 2013; 18: 260-270.
    • (2013) Apoptosis , vol.18 , pp. 260-270
    • Bao, Y.1    Lin, C.2    Ren, J.3
  • 19
    • 84872774489 scopus 로고    scopus 로고
    • Identification of miR-30d as a novel prognostic maker of prostate cancer
    • Kobayashi N, Uemura H, Nagahama K, et al., Identification of miR-30d as a novel prognostic maker of prostate cancer. Oncotarget 2012; 3: 1455-1471.
    • (2012) Oncotarget , vol.3 , pp. 1455-1471
    • Kobayashi, N.1    Uemura, H.2    Nagahama, K.3
  • 20
    • 84855461449 scopus 로고    scopus 로고
    • MicroRNA-30e* promotes human glioma cell invasiveness in an orthotopic xenotransplantation model by disrupting the NF-κB/ IκBα negative feedback loop
    • Jiang L, Lin C, Song L, et al., MicroRNA-30e* promotes human glioma cell invasiveness in an orthotopic xenotransplantation model by disrupting the NF-κB/IκBα negative feedback loop. J Clin Invest 2012; 122: 33-47.
    • (2012) J Clin Invest , vol.122 , pp. 33-47
    • Jiang, L.1    Lin, C.2    Song, L.3
  • 22
    • 78650934318 scopus 로고    scopus 로고
    • MicroRNAs and colon and rectal cancer: Differential expression by tumor location and subtype
    • Slattery ML, Wolff E, Hoffman MD, et al., MicroRNAs and colon and rectal cancer: differential expression by tumor location and subtype. Genes Chromosomes Cancer 2011; 50: 196-206.
    • (2011) Genes Chromosomes Cancer , vol.50 , pp. 196-206
    • Slattery, M.L.1    Wolff, E.2    Hoffman, M.D.3
  • 23
    • 80455160222 scopus 로고    scopus 로고
    • MicroRNA profiling differentiates colorectal cancer according to KRAS status
    • Mosakhani N, Sarhadi VK, Borze I, et al., MicroRNA profiling differentiates colorectal cancer according to KRAS status. Genes Chromosomes Cancer 2012; 51: 1-9.
    • (2012) Genes Chromosomes Cancer , vol.51 , pp. 1-9
    • Mosakhani, N.1    Sarhadi, V.K.2    Borze, I.3
  • 24
    • 84868144684 scopus 로고    scopus 로고
    • Identification and functional screening of microRNAs highly deregulated in colorectal cancer
    • Faltejskova P, Svoboda M, Srutova K, et al., Identification and functional screening of microRNAs highly deregulated in colorectal cancer. J Cell Mol Med 2012; 16: 2655-2666.
    • (2012) J Cell Mol Med , vol.16 , pp. 2655-2666
    • Faltejskova, P.1    Svoboda, M.2    Srutova, K.3
  • 25
    • 51049119231 scopus 로고    scopus 로고
    • Diagnostic and prognostic microRNAs in stage II colon cancer
    • Schepeler T, Reinert JT, Ostenfeld MS, et al., Diagnostic and prognostic microRNAs in stage II colon cancer. Cancer Res 2008; 68: 6416-6424.
    • (2008) Cancer Res , vol.68 , pp. 6416-6424
    • Schepeler, T.1    Reinert, J.T.2    Ostenfeld, M.S.3
  • 26
    • 63449085861 scopus 로고    scopus 로고
    • Centromere protein H is a novel prognostic marker for human non-small cell lung cancer progression and overall patient survival
    • Liao WT, Wang X, Xu LH, et al., Centromere protein H is a novel prognostic marker for human non-small cell lung cancer progression and overall patient survival. Cancer 2009; 115: 1507-1517.
    • (2009) Cancer , vol.115 , pp. 1507-1517
    • Liao, W.T.1    Wang, X.2    Xu, L.H.3
  • 27
    • 79957901659 scopus 로고    scopus 로고
    • HOXB7 as a prognostic factor and mediator of colorectal cancer progression
    • Liao WT, Jiang D, Yuan J, et al., HOXB7 as a prognostic factor and mediator of colorectal cancer progression. Clin Cancer Res 2011; 17: 3569-3578.
    • (2011) Clin Cancer Res , vol.17 , pp. 3569-3578
    • Liao, W.T.1    Jiang, D.2    Yuan, J.3
  • 28
    • 4644309196 scopus 로고    scopus 로고
    • The functions of animal microRNAs
    • DOI 10.1038/nature02871
    • Ambros V., The functions of animal microRNAs. Nature 2004; 431: 350-355. (Pubitemid 39265675)
    • (2004) Nature , vol.431 , Issue.7006 , pp. 350-355
    • Ambros, V.1
  • 29
    • 33750370444 scopus 로고    scopus 로고
    • MicroRNA signatures in human cancers
    • DOI 10.1038/nrc1997, PII NRC1997
    • Calin GA, Croce CM,. MicroRNA signatures in human cancers. Nat Rev Cancer 2006; 6: 857-866. (Pubitemid 44629897)
    • (2006) Nature Reviews Cancer , vol.6 , Issue.11 , pp. 857-866
    • Calin, G.A.1    Croce, C.M.2
  • 30
    • 33645294070 scopus 로고    scopus 로고
    • Oncomirs - MicroRNAs with a role in cancer
    • Esquela-Kerscher A, Slack FJ,. Oncomirs-microRNAs with a role in cancer. Nat Rev Cancer 2006; 6: 259-269.
    • (2006) Nat Rev Cancer , vol.6 , pp. 259-269
    • Esquela-Kerscher, A.1    Slack, F.J.2
  • 31
    • 84869443764 scopus 로고    scopus 로고
    • Implications of microRNAs in colorectal cancer development, diagnosis, prognosis, and therapeutics
    • Zhai H, Ju J,. Implications of microRNAs in colorectal cancer development, diagnosis, prognosis, and therapeutics. Front Genet 2011; 2: ii, 00078.
    • (2011) Front Genet , vol.2 , Issue.2 , pp. 00078
    • Zhai, H.1    Ju, J.2
  • 32
    • 65249180150 scopus 로고    scopus 로고
    • SnapShot: MicroRNAs in cancer
    • e581
    • Spizzo R, Nicoloso MS, Croce CM, et al., SnapShot: microRNAs in cancer. Cell 2009; 137: 586-586, e581.
    • (2009) Cell , vol.137 , pp. 586-586
    • Spizzo, R.1    Nicoloso, M.S.2    Croce, C.M.3
  • 33
    • 73049110243 scopus 로고    scopus 로고
    • The EMT-activator ZEB1 promotes tumorigenicity by repressing stemness-inhibiting microRNAs
    • Wellner U, Schubert J, Burk UC, et al., The EMT-activator ZEB1 promotes tumorigenicity by repressing stemness-inhibiting microRNAs. Nat Cell Biol 2009; 11: 1487-1495.
    • (2009) Nat Cell Biol , vol.11 , pp. 1487-1495
    • Wellner, U.1    Schubert, J.2    Burk, U.C.3
  • 34
    • 84864462131 scopus 로고    scopus 로고
    • Amplification and up-regulation of microRNA-30b in oral squamous cell cancers
    • Shao C, Yu Y, Yu L, et al., Amplification and up-regulation of microRNA-30b in oral squamous cell cancers. Arch Oral Biol 2012; 57: 1012-1017.
    • (2012) Arch Oral Biol , vol.57 , pp. 1012-1017
    • Shao, C.1    Yu, Y.2    Yu, L.3
  • 35
    • 67650243241 scopus 로고    scopus 로고
    • Amplification and overexpression of Hsa-miR-30b, Hsa-miR-30d and KHDRBS3 at 8q24.22-q24.23 in medulloblastoma
    • Lu Y, Ryan SL, Elliott DJ, et al., Amplification and overexpression of Hsa-miR-30b, Hsa-miR-30d and KHDRBS3 at 8q24.22-q24.23 in medulloblastoma. PloS One 2009; 4: e6159.
    • (2009) PloS One , vol.4
    • Lu, Y.1    Ryan, S.L.2    Elliott, D.J.3
  • 36
    • 79960064599 scopus 로고    scopus 로고
    • MiR-30b/30d regulation of GalNAc transferases enhances invasion and immunosuppression during metastasis
    • Gaziel-Sovran A, Segura MF, Di Micco R, et al., miR-30b/30d regulation of GalNAc transferases enhances invasion and immunosuppression during metastasis. Cancer Cell 2011; 20: 104-118.
    • (2011) Cancer Cell , vol.20 , pp. 104-118
    • Gaziel-Sovran, A.1    Segura, M.F.2    Di Micco, R.3
  • 37
    • 84857582036 scopus 로고    scopus 로고
    • Trastuzumab produces therapeutic actions by upregulating miR-26a and miR-30b in breast cancer cells
    • Ichikawa T, Sato F, Terasawa K, et al., Trastuzumab produces therapeutic actions by upregulating miR-26a and miR-30b in breast cancer cells. PLoS One 2012; 7: e31422.
    • (2012) PLoS One , vol.7
    • Ichikawa, T.1    Sato, F.2    Terasawa, K.3
  • 38
    • 81055133663 scopus 로고    scopus 로고
    • A MicroRNA expression profile defining the invasive bladder tumor phenotype
    • e791
    • Wszolek MF, Rieger-Christ KM, Kenney PA, et al., A MicroRNA expression profile defining the invasive bladder tumor phenotype. Urol Oncol 2011; 29: 794-801, e791.
    • (2011) Urol Oncol , vol.29 , pp. 794-801
    • Wszolek, M.F.1    Rieger-Christ, K.M.2    Kenney, P.A.3
  • 39
    • 52049121293 scopus 로고    scopus 로고
    • Mature miR-184 as potential oncogenic microRNA of squamous cell carcinoma of tongue
    • Wong TS, Liu XB, Wong BY, et al., Mature miR-184 as potential oncogenic microRNA of squamous cell carcinoma of tongue. Clin Cancer Res 2008; 14: 2588-2592.
    • (2008) Clin Cancer Res , vol.14 , pp. 2588-2592
    • Wong, T.S.1    Liu, X.B.2    Wong, B.Y.3
  • 40
    • 84883157594 scopus 로고    scopus 로고
    • Effect of miR-21 and miR-30b/c on TRAIL-induced apoptosis in glioma cells
    • Quintavalle C, Donnarumma E, Iaboni M, et al., Effect of miR-21 and miR-30b/c on TRAIL-induced apoptosis in glioma cells. Oncogene 2013; 32: 4001-4008.
    • (2013) Oncogene , vol.32 , pp. 4001-4008
    • Quintavalle, C.1    Donnarumma, E.2    Iaboni, M.3
  • 41
    • 0035855623 scopus 로고    scopus 로고
    • Analysis of FasL and trail induced apoptosis pathways in glioma cells
    • DOI 10.1038/sj.onc.1204810
    • Knight MJ, Riffkin CD, Muscat AM, et al., Analysis of FasL and TRAIL induced apoptosis pathways in glioma cells. Oncogene 2001; 20: 5789-5798. (Pubitemid 32937948)
    • (2001) Oncogene , vol.20 , Issue.41 , pp. 5789-5798
    • Knight, M.J.1    Riffkin, C.D.2    Muscat, A.M.3    Ashley, D.M.4    Hawkins, C.J.5
  • 42
    • 34548669610 scopus 로고    scopus 로고
    • Bcl-2 overexpression in PhIP-induced colon tumors: Cloning of the rat Bcl-2 promoter and characterization of a pathway involving β-catenin, c-Myc and E2F1
    • DOI 10.1038/sj.onc.1210438, PII 1210438
    • Li Q, Dashwood WM, Zhong X, et al., Bcl-2 overexpression in PhIP-induced colon tumors: cloning of the rat Bcl-2 promoter and characterization of a pathway involving β-catenin, c-Myc and E2F1. Oncogene 2007; 26: 6194-6202. (Pubitemid 47414373)
    • (2007) Oncogene , vol.26 , Issue.42 , pp. 6194-6202
    • Li, Q.1    Dashwood, W.M.2    Zhong, X.3    Nakagama, H.4    Dashwood, R.H.5
  • 43
    • 77956190153 scopus 로고    scopus 로고
    • Expressions of the anti-apoptotic genes Bag-1 and Bcl-2 in colon cancer and their relationship
    • Sun N, Meng Q, Tian A,. Expressions of the anti-apoptotic genes Bag-1 and Bcl-2 in colon cancer and their relationship. Am J Surg 2010; 200: 341-345.
    • (2010) Am J Surg , vol.200 , pp. 341-345
    • Sun, N.1    Meng, Q.2    Tian, A.3
  • 44
    • 0024376173 scopus 로고
    • Ras Oncogenes in human cancer: A review
    • Bos JL,. Ras oncogenes in human cancer: a review. Cancer Res 1989; 49: 4682-4689. (Pubitemid 19213607)
    • (1989) Cancer Research , vol.49 , Issue.17 , pp. 4682-4689
    • Bos, J.L.1
  • 49
    • 84880324422 scopus 로고    scopus 로고
    • 8q24 amplification is associated with Myc expression and prostate cancer progression and is an independent predictor of recurrence after radical prostatectomy
    • Fromont G, Godet J, Peyret A, et al., 8q24 amplification is associated with Myc expression and prostate cancer progression and is an independent predictor of recurrence after radical prostatectomy. Hum Pathol 2013; 44: 1617-1623.
    • (2013) Hum Pathol , vol.44 , pp. 1617-1623
    • Fromont, G.1    Godet, J.2    Peyret, A.3
  • 50
    • 55549113578 scopus 로고    scopus 로고
    • Defensins and the dynamic genome: What we can learn from structural variation at human chromosome band 8p23.1
    • Hollox EJ, Barber JC, Brookes AJ, et al., Defensins and the dynamic genome: what we can learn from structural variation at human chromosome band 8p23.1. Genome Res 2008; 18: 1686-1697.
    • (2008) Genome Res , vol.18 , pp. 1686-1697
    • Hollox, E.J.1    Barber, J.C.2    Brookes, A.J.3
  • 51
    • 26444577882 scopus 로고    scopus 로고
    • Copy number polymorphism and expression level variation of the human α-defensin genes DEFA1 and DEFA3
    • DOI 10.1093/hmg/ddi209
    • Aldred PM, Hollox EJ, Armour JA,. Copy number polymorphism and expression level variation of the human α-defensin genes DEFA1 and DEFA3. Hum Mol Genet 2005; 14: 2045-2052. (Pubitemid 41418040)
    • (2005) Human Molecular Genetics , vol.14 , Issue.14 , pp. 2045-2052
    • Aldred, P.M.R.1    Hollox, E.J.2    Armour, J.A.L.3
  • 52
    • 33745623128 scopus 로고    scopus 로고
    • Post-transcriptional regulation of microRNA expression
    • DOI 10.1261/rna.2322506
    • Obernosterer G, Leuschner PJ, Alenius M, et al., Post-transcriptional regulation of microRNA expression. RNA 2006; 12: 1161-1167. (Pubitemid 43990541)
    • (2006) RNA , vol.12 , Issue.7 , pp. 1161-1167
    • Obernosterer, G.1    Leuschner, P.J.F.2    Alenius, M.3    Martinez, J.4
  • 53
    • 0023256456 scopus 로고
    • Prevalence of ras gene mutations in human colorectal cancers
    • DOI 10.1038/327293a0
    • Bos JL, Fearon ER, Hamilton SR, et al., Prevalence of ras gene mutations in human colorectal cancers. Nature 1987; 327: 293-297. (Pubitemid 17075079)
    • (1987) Nature , vol.327 , Issue.6120 , pp. 293-297
    • Bos, J.L.1    Fearon, E.R.2    Hamilton, S.R.3
  • 55
    • 79961173138 scopus 로고    scopus 로고
    • Roles of the Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR pathways in controlling growth and sensitivity to therapy-implications for cancer and aging
    • Steelman LS, Chappell WH, Abrams SL, et al., Roles of the Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR pathways in controlling growth and sensitivity to therapy-implications for cancer and aging. Aging (Albany, NY) 2011; 3: 192-222.
    • (2011) Aging (Albany, NY) , vol.3 , pp. 192-222
    • Steelman, L.S.1    Chappell, W.H.2    Abrams, S.L.3
  • 56
    • 77954903710 scopus 로고    scopus 로고
    • Activity of any class IA PI3K isoform can sustain cell proliferation and survival
    • Foukas LC, Berenjeno IM, Gray A, et al., Activity of any class IA PI3K isoform can sustain cell proliferation and survival. Proc Natl Acad Sci USA 2010; 107: 11381-11386.
    • (2010) Proc Natl Acad Sci USA , vol.107 , pp. 11381-11386
    • Foukas, L.C.1    Berenjeno, I.M.2    Gray, A.3
  • 57
    • 0037380598 scopus 로고    scopus 로고
    • Bcl-2 constitutively suppresses p53-dependent apoptosis in colorectal cancer cells
    • DOI 10.1101/gad.252603
    • Jiang M, Milner J,. Bcl-2 constitutively suppresses p53-dependent apoptosis in colorectal cancer cells. Genes Dev 2003; 17: 832-837. (Pubitemid 36397371)
    • (2003) Genes and Development , vol.17 , Issue.7 , pp. 832-837
    • Jiang, M.1    Milner, J.2


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