Role of hypoxia inducible factor-1 α for interferon synthesis in mouse dendritic cells

Biological Chemistry

Volumn 394, Issue 4, 2013, Pages 495-505

  Wobben, Regina ^a   Hüsecken, Yvonne ^a   Lodewick, Claudia ^a   Gibbert, Kathrin ^a   Fandrey, Joachim ^a   Winning, Sandra ^a  

^a UNIVERSITY OF DUISBURG ESSEN   (Germany)

Author keywords

Dendritic cells; Hypoxia; Inflammation; Type I interferons

Indexed keywords

ALPHA INTERFERON; BETA INTERFERON; GRANZYME B; HYPOXIA INDUCIBLE FACTOR 1ALPHA; POLYINOSINIC POLYCYTIDYLIC ACID;

ADAPTIVE IMMUNITY; ANIMAL CELL; ARTICLE; CONTROLLED STUDY; CYTOTOXIC T LYMPHOCYTE; DENDRITIC CELL; INTERFERON PRODUCTION; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; T LYMPHOCYTE ACTIVATION;

ANIMALS; ANOXIA; BLOTTING, WESTERN; CELLS, CULTURED; DENDRITIC CELLS; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; INTERFERON TYPE I; INTERFERONS; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; REAL-TIME POLYMERASE CHAIN REACTION;

EID: 84882269271     PISSN: 14316730     EISSN: 14374315     Source Type: Journal    
DOI: 10.1515/hsz-2012-0320     Document Type: Article

References (45)

1. Baig, E. and Fish, E.N. (2008). Distinct signature type I interferon responses are determined by the infecting virus and the target cell. Antivir. Ther. 13, 409-422.
2. Banchereau, J. and Steinman, R.M. (1998). Dendritic cells and the control of immunity. Nature 392, 245-252.
3. Beutler, B. (2004). Toll-like receptors and their place in immunology. Where does the immune response to infection begin? Nat. Rev. Immunol. 4, 498.
4. Bosco, M.C., Puppo, M., Blengio, F., Fraone, T., Cappello, P., Giovarelli, M., and Varesio, L. (2008). Monocytes and dendritic cells in a hypoxic environment: spotlights on chemotaxis and migration. Immunobiology. 213, 733-749.
5. Chomczynski, P. and Sacchi, N. (1987). Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal. Biochem. 162, 156-159.
6. Cramer, T. and Johnson, R.S. (2003). A novel role for the hypoxia inducible transcription factor HIF-1α: critical regulation of inflammatory cell function. Cell Cycle 2, 192-193.
7. Cramer, T., Yamanishi, Y., Clausen, B.E., Förster, I., Pawlinski, R., Mackman, N., Haase, V.H., Jaenisch, R., Corr, M., Nizet, V., et al. (2003). HIF-1α is essential for myeloid cell-mediated inflammation. Cell 112, 645-657.
8. Erratum in: Cell. 113, 419.
9. Fandrey, J., Gorr, T.A., and Gassmann, M. (2006). Regulating cellular oxygen sensing by hydroxylation. Cardiovasc. Res. 71, 642-651.
10. Frede, S., Stockmann, C., Freitag, P., and Fandrey, J. (2006). Bacterial lipopolysaccharide induces HIF-1 activation in human monocytes via p44/42 MAPK and NF-κB. Biochem. J. 396, 517-527.
11. Frede, S., Stockmann, C., Winning, S., Freitag, P., and Fandrey, J. (2009). Hypoxia-inducible factor (HIF) 1α accumulation and HIF target gene expression are impaired after induction of endotoxin tolerance. J. Immunol. 182, 6470-6476.
12. Gerlach, N., Gibbert, K., Alter, C., Nair, S., Zelinskyy, G., James, C.M., and Dittmer, U. (2009). Anti-retroviral effects of type I IFN subtypes in vivo. Eur. J. Immunol. 39, 136-146.
13. Gibbert, K. and Dittmer, U. (2011). Distinct antiviral activities of IFN-α subtypes. Immunotherapy 3, 813-816.
14. Gibbert, K., Joedicke, J.J., Meryk, A., Trilling, M., Francois, S., Duppach, J., Kraft, A., Lang, K.S., and Dittmer, U. (2012). Interferon-α subtype 11 activates NK cells and enables control of retroviral infection. PLoS Pathog. 8, e1002868.
15. Granucci, F., Zanoni, I., and Ricciardi-Castagnoli, P. (2008). Central role of dendritic cells in the regulation and deregulation of immune responses. Cell. Mol. Life Sci. 65, 1683-1697.
16. Hellwig-Bürgel, T., Rutkowski, K., Metzen, E., Fandrey, F., and Jelkmann, W. (1999). Interleukin-1β and tumor necrosis factor-α stimulate DNA binding of hypoxia-inducible factor-1. Blood 94, 1561-1567.
17. Jantsch, J., Chakravortty, D., Turza, N., Prechtel, A.T., Buchholz, B., Gerlach, R.G., Volke, M., Gläsner, J., Warnecke, C., Wiesener, M.S., et al. (2008). Hypoxia and hypoxia-inducible factor-1α modulate lipopolysaccharide-induced dendritic cell activation and function. J. Immunol. 180, 4697-4705.
18. Jantsch, J., Wiese, M., Schödel, J., Castiglione, K., Gläsner, J., Kolbe, S., Mole, D., Schleicher, U., Eckardt, K.U., Hensel, M., et al. (2011). Toll-like receptor activation and hypoxia use distinct signaling pathways to stabilize hypoxia-inducible factor 1α (HIF1A) and result in differential HIF1A-dependent gene expression. J. Leukoc. Biol. 90, 551-562.
19. Karhausen, J., Haase, V.H., and Colgan, S.P. (2005). Inflammatory hypoxia: role of hypoxia-inducible factor. Cell Cycle 4, 256-258.
20. Kawai, T. and Akira, S. (2006). Innate immune recognition of viral infection. Nat. Immunol. 7, 131-137.
21. Kelly, J.M., Sterry, S.J., Cose, S., Turner, S.J., Fecondo, J., Rodda, S., Fink, P.J., and Carbone, F.R. (1993). Identification of conserved T cell receptor CDR3 residues contacting known exposed peptide side chains from a major histocompatibility complex class I-bound determinant. Eur. J. Immunol. 23, 3318-3326.
22. Köhler, T., Reizis, B., Johnson, R.S., Weighardt, H., and Förster, I. (2012). Influence of hypoxia-inducible factor 1α on dendritic cell differentiation and migration. Eur. J. Immunol. 42, 1226-1236.
23. Kong, T., Eltzschig, H.K., Karhausen, J., Colgan, S.P., and Shelley, C.S. (2004). Leukocyte adhesion during hypoxia is mediated by HIF-1-dependent induction of β2 integrin gene expression. Proc. Natl. Acad. Sci. USA 101, 10440-10445.
24. Mancino, A., Schioppa, T., Larghi, P., Pasqualini, F., Nebuloni, M., Chen, I.H., Sozzani, S., Austyn, J.M., Mantovani, A., and Sica, A. (2008). Divergent effects of hypoxia on dendritic cell functions. Blood 112, 3723-3734.
25. Martinez, J., Huang, X., and Yang, Y. (2008). Direct action of type I IFN on NK cells is required for their activation in response to vaccinia viral infection in vivo. J. Immunol. 180, 1592-1597.
26. Moll, H.P., Maier, T., Zommer, A., Lavoie, T., and Brostjan, C. (2010) The differential activity of interferon-α subtypes is consistent among distinct target genes and cell types. Cytokine 53, 52-59.
27. Muthana, M., Murdoch, C., and Lewis, C.E. (2005). Hypoxia regulates macrophage functions in inflammation. J. Immunol. 175, 6257-6263.
28. Naldini, A., Morena, E., Pucci, A., Miglietta, D., Riboldi, E., Sozzani, S., and Carraro, F. (2012). Hypoxia affects dendritic cell survival: role of the hypoxia-inducible factor-1α and lipopolysaccharide. J. Cell. Physiol. 227, 587-595.
29. Paone, A., Galli, R., Gabellini, C., Lukashev, D., Starace, D., Gorlach, A., De Cesaris, P., Ziparo, E., Del Bufalo, D., Sitkovsky, M.V., et al. (2010). Toll-like receptor 3 regulates angiogenesis and apoptosis in prostate cancer cell lines through hypoxiainducible factor 1α . Neoplasia 12, 539-549.
30. van Pesch, V., Lanaya, H., Renauld, J.C., and Michiels, T. (2004). Characterization of the murine α interferon gene family. J. Virol. 78, 8219-8228.
31. Randolph, G.J., Ochando, J., and Partida-Sánchez, S. (2008). Migration of dendritic cell subsets and their precursors. Annu. Rev. Immunol. 26, 293-316.
32. Semenza, G.L., Agani, F., Booth, G., Forsythe, J., Iyer, N., Jiang, B.H., Leung, S., Roe, R., Wiener, C., and Yu, A. (1997). Structural and functional analysis of hypoxia-inducible factor 1. Kidney Int. 51, 553-555.
33. Steinman, R.M. (1973). Identification of a novel cell type in peripheral lymphoid organs of mice I. Morphology, quantitation, tissue redistribution. J. Exp. Med. 137, 1142-1162.
34. Tafuri, A., Shahinian, A., Bladt, F., Yoshinaga, S.K., Jordana, M., Wakeham, A., Boucher, L.M., Bouchard, D., Chan, V.S., Duncan, G., et al. (2001). ICOS is essential for effective T-helper-cell responses. Nature 409, 105-109.
35. Takeshita, F., Gursel, I., Ishii, K.J., Suzuki, K., Gursel, M., and Klinman, D.M. (2004). Signal transduction pathways mediated by the interaction of CpG DNA with Toll-like receptor 9. Semin Immunol. 16, 17-22.
36. Trinchieri, G., Santoli, D., Dee, R.R., and Knowles, B.B. (1978). Anti-viral activity induced by culturing lymphocytes with tumor-derived or virus-transformed cells. Identification of the anti-viral activity as interferon and characterization of the human effector lymphocyte subpopulation. J. Exp. Med. 147, 1299-1313.
37. Walseng, E., Kazuyuki, F., Goldszmid, R., Weih, K., Sher, A., and Roche, P. (2010). Dendritic cell activation prevents MHC Class II ubiquitination and promotes MHC Class II survival regardless of the activation stimulus. J. Biol. Chem. 285, 41749-41754.
38. Weigert, A., Weichand, B., Sekar, D., Sha, W., Hahn, C., Mora, J., Ley, S., Essler, S., Dehne, N., Brüne, B. (2012). HIF-1? is a negative regulator of plasmacytoid DC development in vitro and in vivo. Blood, 120, 3001-3006.
39. Weis, S.M. and Cheresh, D.A. (2005). Pathophysiological consequences of VEGF-induced vascular permeability. Nature 437, 497-504.
40. Westra, J., Brouwer, E., Bos, R., Posthumus, M.D., Doornbos-van der Meer, B., Kallenberg, C.G., and Limburg, P.C. (2007). Regulation of cytokine-induced HIF-1α expression in rheumatoid synovial fibroblasts. Ann. N. Y. Acad. Sci. 1108, 340-348.
41. Winer, J., Jung, C.K., Shackel, I., and Williams, P.M. (1999). Development and validation of real-time quantitative reverse transcriptase-polymerase chain reaction for monitoring gene expression in cardiac myocytes in vitro. Anal. Biochem. 270, 41-49.
42. Winning, S. and Fandrey, J. (2012). HIF and inflammation. In: Tumour hypoxia: molecular mechanisms and clinical implications. (Bratislava, Slovakia: VEDA, SAS Publishing House), pp. 339-372.
43. Yang, D., Zhang, Y., Nguyen, H.G., Koupenova, M., Chauhan, A.K., Makitalo, M., Jones, M.R., St. Hilaire, C., Seldin, D.C., Toselli, P., et al. (2006). The A2B adenosine receptor protects against inflammation and excessive vascular adhesion. J. Clin. Invest. 116, 1913-1923.
44. Zhang, B., Zhang, J., and Tian, Z. (2008). Comparison in the effects of IL-2, IL-12, IL-15 and IFNα on gene regulation of granzymes of human NK cell line NK-92. Int. Immunopharmacol. 8, 989-996.
45. Zittermann, S.I. and Issekutz, A.C. (2006). Endothelial growth factors VEGF and bFGF differentially enhance monocyte and neutrophil recruitment to inflammation. J. Leukoc. Biol. 80, 247-257.