-
1
-
-
35548974423
-
Identification of stem cells in small intestine and colon by marker gene Lgr5
-
N. Barker, J.H. van Es, J. Kuipers, P. Kujala, M. van den Born, M. Cozijnsen, A. Haegebarth, J. Korving, H. Begthel, P.J. Peters, and H. Clevers Identification of stem cells in small intestine and colon by marker gene Lgr5 Nature 449 2007 1003 1007
-
(2007)
Nature
, vol.449
, pp. 1003-1007
-
-
Barker, N.1
Van Es, J.H.2
Kuipers, J.3
Kujala, P.4
Van Den Born, M.5
Cozijnsen, M.6
Haegebarth, A.7
Korving, J.8
Begthel, H.9
Peters, P.J.10
Clevers, H.11
-
2
-
-
59049106578
-
Crypt stem cells as the cells-of-origin of intestinal cancer
-
N. Barker, R.A. Ridgway, J.H. van Es, M. van de Wetering, H. Begthel, M. van den Born, E. Danenberg, A.R. Clarke, O.J. Sansom, and H. Clevers Crypt stem cells as the cells-of-origin of intestinal cancer Nature 457 2009 608 611
-
(2009)
Nature
, vol.457
, pp. 608-611
-
-
Barker, N.1
Ridgway, R.A.2
Van Es, J.H.3
Van De Wetering, M.4
Begthel, H.5
Van Den Born, M.6
Danenberg, E.7
Clarke, A.R.8
Sansom, O.J.9
Clevers, H.10
-
3
-
-
79961237652
-
Deletion of mouse Porcn blocks Wnt ligand secretion and reveals an ectodermal etiology of human focal dermal hypoplasia/Goltz syndrome
-
J.J. Barrott, G.M. Cash, A.P. Smith, J.R. Barrow, and L.C. Murtaugh Deletion of mouse Porcn blocks Wnt ligand secretion and reveals an ectodermal etiology of human focal dermal hypoplasia/Goltz syndrome Proc. Natl. Acad. Sci. USA 108 2011 12752 12757
-
(2011)
Proc. Natl. Acad. Sci. USA
, vol.108
, pp. 12752-12757
-
-
Barrott, J.J.1
Cash, G.M.2
Smith, A.P.3
Barrow, J.R.4
Murtaugh, L.C.5
-
4
-
-
34547956892
-
Sox9 regulates cell proliferation and is required for Paneth cell differentiation in the intestinal epithelium
-
P. Bastide, C. Darido, J. Pannequin, R. Kist, S. Robine, C. Marty-Double, F. Bibeau, G. Scherer, D. Joubert, and F. Hollande et al. Sox9 regulates cell proliferation and is required for Paneth cell differentiation in the intestinal epithelium J. Cell Biol. 178 2007 635 648
-
(2007)
J. Cell Biol.
, vol.178
, pp. 635-648
-
-
Bastide, P.1
Darido, C.2
Pannequin, J.3
Kist, R.4
Robine, S.5
Marty-Double, C.6
Bibeau, F.7
Scherer, G.8
Joubert, D.9
Hollande, F.10
-
5
-
-
79959281790
-
Porcupine homolog is required for canonical Wnt signaling and gastrulation in mouse embryos
-
S. Biechele, B.J. Cox, and J. Rossant Porcupine homolog is required for canonical Wnt signaling and gastrulation in mouse embryos Dev. Biol. 355 2011 275 285
-
(2011)
Dev. Biol.
, vol.355
, pp. 275-285
-
-
Biechele, S.1
Cox, B.J.2
Rossant, J.3
-
6
-
-
84879676304
-
Porcn-dependent Wnt signaling is not required prior to mouse gastrulation
-
S. Biechele, K. Cockburn, F. Lanner, B.J. Cox, and J. Rossant Porcn-dependent Wnt signaling is not required prior to mouse gastrulation Development 140 2013 2961 2971
-
(2013)
Development
, vol.140
, pp. 2961-2971
-
-
Biechele, S.1
Cockburn, K.2
Lanner, F.3
Cox, B.J.4
Rossant, J.5
-
7
-
-
79960990066
-
R-spondins function as ligands of the orphan receptors LGR4 and LGR5 to regulate Wnt/beta-catenin signaling
-
K.S. Carmon, X. Gong, Q. Lin, A. Thomas, and Q. Liu R-spondins function as ligands of the orphan receptors LGR4 and LGR5 to regulate Wnt/beta-catenin signaling Proc. Natl. Acad. Sci. USA 108 2011 11452 11457
-
(2011)
Proc. Natl. Acad. Sci. USA
, vol.108
, pp. 11452-11457
-
-
Carmon, K.S.1
Gong, X.2
Lin, Q.3
Thomas, A.4
Liu, Q.5
-
8
-
-
58249122326
-
Small molecule-mediated disruption of Wnt-dependent signaling in tissue regeneration and cancer
-
B. Chen, M.E. Dodge, W. Tang, J. Lu, Z. Ma, C.-W. Fan, S. Wei, W. Hao, J. Kilgore, and N.S. Williams et al. Small molecule-mediated disruption of Wnt-dependent signaling in tissue regeneration and cancer Nat. Chem. Biol. 5 2009 100 107
-
(2009)
Nat. Chem. Biol.
, vol.5
, pp. 100-107
-
-
Chen, B.1
Dodge, M.E.2
Tang, W.3
Lu, J.4
Ma, Z.5
Fan, C.-W.6
Wei, S.7
Hao, W.8
Kilgore, J.9
Williams, N.S.10
-
9
-
-
0016325705
-
Origin, differentiation and renewal of the four main epithelial cell types in the mouse small intestine. V. Unitarian Theory of the origin of the four epithelial cell types
-
H. Cheng, and C.P. Leblond Origin, differentiation and renewal of the four main epithelial cell types in the mouse small intestine. V. Unitarian Theory of the origin of the four epithelial cell types Am. J. Anat. 141 1974 537 561
-
(1974)
Am. J. Anat.
, vol.141
, pp. 537-561
-
-
Cheng, H.1
Leblond, C.P.2
-
10
-
-
84880548336
-
The intestinal crypt, a prototype stem cell compartment
-
H. Clevers The intestinal crypt, a prototype stem cell compartment Cell 154 2013 274 284
-
(2013)
Cell
, vol.154
, pp. 274-284
-
-
Clevers, H.1
-
11
-
-
77956942286
-
WLS-dependent secretion of WNT3A requires Ser209 acylation and vacuolar acidification
-
G.S. Coombs, J. Yu, C.A. Canning, C.A. Veltri, T.M. Covey, J.K. Cheong, V. Utomo, N. Banerjee, Z.H. Zhang, and R.C. Jadulco et al. WLS-dependent secretion of WNT3A requires Ser209 acylation and vacuolar acidification J. Cell Sci. 123 2010 3357 3367
-
(2010)
J. Cell Sci.
, vol.123
, pp. 3357-3367
-
-
Coombs, G.S.1
Yu, J.2
Canning, C.A.3
Veltri, C.A.4
Covey, T.M.5
Cheong, J.K.6
Utomo, V.7
Banerjee, N.8
Zhang, Z.H.9
Jadulco, R.C.10
-
12
-
-
80051926611
-
Lgr5 homologues associate with Wnt receptors and mediate R-spondin signalling
-
W. de Lau, N. Barker, T.Y. Low, B.-K. Koo, V.S.W. Li, H. Teunissen, P. Kujala, A. Haegebarth, P.J. Peters, and M. van de Wetering et al. Lgr5 homologues associate with Wnt receptors and mediate R-spondin signalling Nature 476 2011 293 297
-
(2011)
Nature
, vol.476
, pp. 293-297
-
-
De Lau, W.1
Barker, N.2
Low, T.Y.3
Koo, B.-K.4
Li, V.S.W.5
Teunissen, H.6
Kujala, P.7
Haegebarth, A.8
Peters, P.J.9
Van De Wetering, M.10
-
13
-
-
0028122465
-
Dominant-negative and targeted null mutations in the endothelial receptor tyrosine kinase, tek, reveal a critical role in vasculogenesis of the embryo
-
D.J. Dumont, G. Gradwohl, G.H. Fong, M.C. Puri, M. Gertsenstein, A. Auerbach, and M.L. Breitman Dominant-negative and targeted null mutations in the endothelial receptor tyrosine kinase, tek, reveal a critical role in vasculogenesis of the embryo Genes Dev. 8 1994 1897 1909
-
(1994)
Genes Dev.
, vol.8
, pp. 1897-1909
-
-
Dumont, D.J.1
Gradwohl, G.2
Fong, G.H.3
Puri, M.C.4
Gertsenstein, M.5
Auerbach, A.6
Breitman, M.L.7
-
14
-
-
84861871905
-
Functional intestinal stem cells after Paneth cell ablation induced by the loss of transcription factor Math1 (Atoh1)
-
A. Durand, B. Donahue, G. Peignon, F. Letourneur, N. Cagnard, C. Slomianny, C. Perret, N.F. Shroyer, and B. Romagnolo Functional intestinal stem cells after Paneth cell ablation induced by the loss of transcription factor Math1 (Atoh1) Proc. Natl. Acad. Sci. USA 109 2012 8965 8970
-
(2012)
Proc. Natl. Acad. Sci. USA
, vol.109
, pp. 8965-8970
-
-
Durand, A.1
Donahue, B.2
Peignon, G.3
Letourneur, F.4
Cagnard, N.5
Slomianny, C.6
Perret, C.7
Shroyer, N.F.8
Romagnolo, B.9
-
15
-
-
4043059169
-
Tissue-specific and inducible Cre-mediated recombination in the gut epithelium
-
F. el Marjou, K.-P. Janssen, B.H.-J. Chang, M. Li, V. Hindie, L. Chan, D. Louvard, P. Chambon, D. Metzger, and S. Robine Tissue-specific and inducible Cre-mediated recombination in the gut epithelium Genesis 39 2004 186 193
-
(2004)
Genesis
, vol.39
, pp. 186-193
-
-
El Marjou, F.1
Janssen, K.-P.2
Chang, B.H.-J.3
Li, M.4
Hindie, V.5
Chan, L.6
Louvard, D.7
Chambon, P.8
Metzger, D.9
Robine, S.10
-
16
-
-
0032129239
-
GFR alpha1-deficient mice have deficits in the enteric nervous system and kidneys
-
H. Enomoto, T. Araki, A. Jackman, R.O. Heuckeroth, W.D. Snider, E.M. Johnson Jr., and J. Milbrandt GFR alpha1-deficient mice have deficits in the enteric nervous system and kidneys Neuron 21 1998 317 324
-
(1998)
Neuron
, vol.21
, pp. 317-324
-
-
Enomoto, H.1
Araki, T.2
Jackman, A.3
Heuckeroth, R.O.4
Snider, W.D.5
Johnson, Jr.E.M.6
Milbrandt, J.7
-
17
-
-
84869864069
-
Redundant sources of Wnt regulate intestinal stem cells and promote formation of Paneth cells
-
H.F. Farin, J.H. Van Es, and H. Clevers Redundant sources of Wnt regulate intestinal stem cells and promote formation of Paneth cells Gastroenterology 143 2012 1518 1529.e7
-
(2012)
Gastroenterology
, vol.143
-
-
Farin, H.F.1
Van Es, J.H.2
Clevers, H.3
-
18
-
-
0030863618
-
Examining the role of Paneth cells in the small intestine by lineage ablation in transgenic mice
-
E.M. Garabedian, L.J. Roberts, M.S. McNevin, and J.I. Gordon Examining the role of Paneth cells in the small intestine by lineage ablation in transgenic mice J. Biol. Chem. 272 1997 23729 23740
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 23729-23740
-
-
Garabedian, E.M.1
Roberts, L.J.2
McNevin, M.S.3
Gordon, J.I.4
-
19
-
-
80053560465
-
LGR4 and LGR5 are R-spondin receptors mediating Wnt/β-catenin and Wnt/PCP signalling
-
A. Glinka, C. Dolde, N. Kirsch, Y.L. Huang, O. Kazanskaya, D. Ingelfinger, M. Boutros, C.M. Cruciat, and C. Niehrs LGR4 and LGR5 are R-spondin receptors mediating Wnt/β-catenin and Wnt/PCP signalling EMBO Rep. 12 2011 1055 1061
-
(2011)
EMBO Rep.
, vol.12
, pp. 1055-1061
-
-
Glinka, A.1
Dolde, C.2
Kirsch, N.3
Huang, Y.L.4
Kazanskaya, O.5
Ingelfinger, D.6
Boutros, M.7
Cruciat, C.M.8
Niehrs, C.9
-
20
-
-
23244448347
-
Expression pattern of Wnt signaling components in the adult intestine
-
A. Gregorieff, D. Pinto, H. Begthel, O. Destrée, M. Kielman, and H. Clevers Expression pattern of Wnt signaling components in the adult intestine Gastroenterology 129 2005 626 638
-
(2005)
Gastroenterology
, vol.129
, pp. 626-638
-
-
Gregorieff, A.1
Pinto, D.2
Begthel, H.3
Destrée, O.4
Kielman, M.5
Clevers, H.6
-
21
-
-
34347326153
-
Deficiency of PORCN, a regulator of Wnt signaling, is associated with focal dermal hypoplasia
-
K.-H. Grzeschik, D. Bornholdt, F. Oeffner, A. König, M. del Carmen Boente, H. Enders, B. Fritz, M. Hertl, U. Grasshoff, and K. Höfling et al. Deficiency of PORCN, a regulator of Wnt signaling, is associated with focal dermal hypoplasia Nat. Genet. 39 2007 833 835
-
(2007)
Nat. Genet.
, vol.39
, pp. 833-835
-
-
Grzeschik, K.-H.1
Bornholdt, D.2
Oeffner, F.3
König, A.4
Del Carmen Boente, M.5
Enders, H.6
Fritz, B.7
Hertl, M.8
Grasshoff, U.9
Höfling, K.10
-
22
-
-
84863543371
-
Structural basis of Wnt recognition by Frizzled
-
C.Y. Janda, D. Waghray, A.M. Levin, C. Thomas, and K.C. Garcia Structural basis of Wnt recognition by Frizzled Science 337 2012 59 64
-
(2012)
Science
, vol.337
, pp. 59-64
-
-
Janda, C.Y.1
Waghray, D.2
Levin, A.M.3
Thomas, C.4
Garcia, K.C.5
-
23
-
-
34547525409
-
Phases of canonical Wnt signaling during the development of mouse intestinal epithelium
-
B.M. Kim, J. Mao, M.M. Taketo, and R.A. Shivdasani Phases of canonical Wnt signaling during the development of mouse intestinal epithelium Gastroenterology 133 2007 529 538
-
(2007)
Gastroenterology
, vol.133
, pp. 529-538
-
-
Kim, B.M.1
Mao, J.2
Taketo, M.M.3
Shivdasani, R.A.4
-
24
-
-
84863230213
-
Intact function of Lgr5 receptor-expressing intestinal stem cells in the absence of Paneth cells
-
T.-H. Kim, S. Escudero, and R.A. Shivdasani Intact function of Lgr5 receptor-expressing intestinal stem cells in the absence of Paneth cells Proc. Natl. Acad. Sci. USA 109 2012 3932 3937
-
(2012)
Proc. Natl. Acad. Sci. USA
, vol.109
, pp. 3932-3937
-
-
Kim, T.-H.1
Escudero, S.2
Shivdasani, R.A.3
-
25
-
-
0031766557
-
Wnt-4 is a mesenchymal signal for epithelial transformation of metanephric mesenchyme in the developing kidney
-
A. Kispert, S. Vainio, and A.P. McMahon Wnt-4 is a mesenchymal signal for epithelial transformation of metanephric mesenchyme in the developing kidney Development 125 1998 4225 4234
-
(1998)
Development
, vol.125
, pp. 4225-4234
-
-
Kispert, A.1
Vainio, S.2
McMahon, A.P.3
-
26
-
-
0030975671
-
Constitutive transcriptional activation by a beta-catenin-Tcf complex in APC-/- colon carcinoma
-
V. Korinek, N. Barker, P.J. Morin, D. van Wichen, R. de Weger, K.W. Kinzler, B. Vogelstein, and H. Clevers Constitutive transcriptional activation by a beta-catenin-Tcf complex in APC-/- colon carcinoma Science 275 1997 1784 1787
-
(1997)
Science
, vol.275
, pp. 1784-1787
-
-
Korinek, V.1
Barker, N.2
Morin, P.J.3
Van Wichen, D.4
De Weger, R.5
Kinzler, K.W.6
Vogelstein, B.7
Clevers, H.8
-
27
-
-
0031848068
-
Depletion of epithelial stem-cell compartments in the small intestine of mice lacking Tcf-4
-
V. Korinek, N. Barker, P. Moerer, E. van Donselaar, G. Huls, P.J. Peters, and H. Clevers Depletion of epithelial stem-cell compartments in the small intestine of mice lacking Tcf-4 Nat. Genet. 19 1998 379 383
-
(1998)
Nat. Genet.
, vol.19
, pp. 379-383
-
-
Korinek, V.1
Barker, N.2
Moerer, P.3
Van Donselaar, E.4
Huls, G.5
Peters, P.J.6
Clevers, H.7
-
28
-
-
0346458662
-
Essential requirement for Wnt signaling in proliferation of adult small intestine and colon revealed by adenoviral expression of Dickkopf-1
-
F. Kuhnert, C.R. Davis, H.-T. Wang, P. Chu, M. Lee, J. Yuan, R. Nusse, and C.J. Kuo Essential requirement for Wnt signaling in proliferation of adult small intestine and colon revealed by adenoviral expression of Dickkopf-1 Proc. Natl. Acad. Sci. USA 101 2004 266 271
-
(2004)
Proc. Natl. Acad. Sci. USA
, vol.101
, pp. 266-271
-
-
Kuhnert, F.1
Davis, C.R.2
Wang, H.-T.3
Chu, P.4
Lee, M.5
Yuan, J.6
Nusse, R.7
Kuo, C.J.8
-
29
-
-
81255143242
-
Intestinal subepithelial myofibroblasts support in vitro and in vivo growth of human small intestinal epithelium
-
N. Lahar, N.Y. Lei, J. Wang, Z. Jabaji, S.C. Tung, V. Joshi, M. Lewis, M. Stelzner, M.G. Martín, and J.C.Y. Dunn Intestinal subepithelial myofibroblasts support in vitro and in vivo growth of human small intestinal epithelium PLoS ONE 6 2011 e26898
-
(2011)
PLoS ONE
, vol.6
, pp. 26898
-
-
Lahar, N.1
Lei, N.Y.2
Wang, J.3
Jabaji, Z.4
Tung, S.C.5
Joshi, V.6
Lewis, M.7
Stelzner, M.8
Martín, M.G.9
Dunn, J.C.Y.10
-
30
-
-
84863290593
-
Deletion of Porcn in mice leads to multiple developmental defects and models human focal dermal hypoplasia (Goltz syndrome)
-
W. Liu, T.M. Shaver, A. Balasa, M.C. Ljungberg, X. Wang, S. Wen, H. Nguyen, and I.B. Van den Veyver Deletion of Porcn in mice leads to multiple developmental defects and models human focal dermal hypoplasia (Goltz syndrome) PLoS ONE 7 2012 e32331
-
(2012)
PLoS ONE
, vol.7
, pp. 32331
-
-
Liu, W.1
Shaver, T.M.2
Balasa, A.3
Ljungberg, M.C.4
Wang, X.5
Wen, S.6
Nguyen, H.7
Van Den Veyver, I.B.8
-
31
-
-
84890281677
-
Targeting Wnt-driven cancer through the inhibition of Porcupine by LGK974
-
J. Liu, S. Pan, M.H. Hsieh, N. Ng, F. Sun, T. Wang, S. Kasibhatla, A.G. Schuller, A.G. Li, and D. Cheng et al. Targeting Wnt-driven cancer through the inhibition of Porcupine by LGK974 Proc. Natl. Acad. Sci. USA 110 2013 20224 20229
-
(2013)
Proc. Natl. Acad. Sci. USA
, vol.110
, pp. 20224-20229
-
-
Liu, J.1
Pan, S.2
Hsieh, M.H.3
Ng, N.4
Sun, F.5
Wang, T.6
Kasibhatla, S.7
Schuller, A.G.8
Li, A.G.9
Cheng, D.10
-
32
-
-
33845352082
-
Wnts as ligands: Processing, secretion and reception
-
A.J. Mikels, and R. Nusse Wnts as ligands: processing, secretion and reception Oncogene 25 2006 7461 7468
-
(2006)
Oncogene
, vol.25
, pp. 7461-7468
-
-
Mikels, A.J.1
Nusse, R.2
-
33
-
-
34547549553
-
SOX9 is required for the differentiation of paneth cells in the intestinal epithelium
-
Y. Mori-Akiyama, M. van den Born, J.H. van Es, S.R. Hamilton, H.P. Adams, J. Zhang, H. Clevers, and B. de Crombrugghe SOX9 is required for the differentiation of paneth cells in the intestinal epithelium Gastroenterology 133 2007 539 546
-
(2007)
Gastroenterology
, vol.133
, pp. 539-546
-
-
Mori-Akiyama, Y.1
Van Den Born, M.2
Van Es, J.H.3
Hamilton, S.R.4
Adams, H.P.5
Zhang, J.6
Clevers, H.7
De Crombrugghe, B.8
-
34
-
-
0030949463
-
Activation of beta-catenin-Tcf signaling in colon cancer by mutations in beta-catenin or APC
-
P.J. Morin, A.B. Sparks, V. Korinek, N. Barker, H. Clevers, B. Vogelstein, and K.W. Kinzler Activation of beta-catenin-Tcf signaling in colon cancer by mutations in beta-catenin or APC Science 275 1997 1787 1790
-
(1997)
Science
, vol.275
, pp. 1787-1790
-
-
Morin, P.J.1
Sparks, A.B.2
Korinek, V.3
Barker, N.4
Clevers, H.5
Vogelstein, B.6
Kinzler, K.W.7
-
35
-
-
84864313614
-
A uniform human Wnt expression library reveals a shared secretory pathway and unique signaling activities
-
R. Najdi, K. Proffitt, S. Sprowl, S. Kaur, J. Yu, T.M. Covey, D.M. Virshup, and M.L. Waterman A uniform human Wnt expression library reveals a shared secretory pathway and unique signaling activities Differentiation 84 2012 203 213
-
(2012)
Differentiation
, vol.84
, pp. 203-213
-
-
Najdi, R.1
Proffitt, K.2
Sprowl, S.3
Kaur, S.4
Yu, J.5
Covey, T.M.6
Virshup, D.M.7
Waterman, M.L.8
-
36
-
-
84870252814
-
The complex world of WNT receptor signalling
-
C. Niehrs The complex world of WNT receptor signalling Nat. Rev. Mol. Cell Biol. 13 2012 767 779
-
(2012)
Nat. Rev. Mol. Cell Biol.
, vol.13
, pp. 767-779
-
-
Niehrs, C.1
-
37
-
-
34447527647
-
Wnt/beta-catenin signaling regulates nephron induction during mouse kidney development
-
J.S. Park, M.T. Valerius, and A.P. McMahon Wnt/beta-catenin signaling regulates nephron induction during mouse kidney development Development 134 2007 2533 2539
-
(2007)
Development
, vol.134
, pp. 2533-2539
-
-
Park, J.S.1
Valerius, M.T.2
McMahon, A.P.3
-
38
-
-
0037829660
-
Canonical Wnt signals are essential for homeostasis of the intestinal epithelium
-
D. Pinto, A. Gregorieff, H. Begthel, and H. Clevers Canonical Wnt signals are essential for homeostasis of the intestinal epithelium Genes Dev. 17 2003 1709 1713
-
(2003)
Genes Dev.
, vol.17
, pp. 1709-1713
-
-
Pinto, D.1
Gregorieff, A.2
Begthel, H.3
Clevers, H.4
-
39
-
-
77958188278
-
Mesenchymal cells of the intestinal lamina propria
-
D.W. Powell, I.V. Pinchuk, J.I. Saada, X. Chen, and R.C. Mifflin Mesenchymal cells of the intestinal lamina propria Annu. Rev. Physiol. 73 2011 213 237
-
(2011)
Annu. Rev. Physiol.
, vol.73
, pp. 213-237
-
-
Powell, D.W.1
Pinchuk, I.V.2
Saada, J.I.3
Chen, X.4
Mifflin, R.C.5
-
40
-
-
84867280731
-
Precise regulation of porcupine activity is required for physiological Wnt signaling
-
K.D. Proffitt, and D.M. Virshup Precise regulation of porcupine activity is required for physiological Wnt signaling J. Biol. Chem. 287 2012 34167 34178
-
(2012)
J. Biol. Chem.
, vol.287
, pp. 34167-34178
-
-
Proffitt, K.D.1
Virshup, D.M.2
-
41
-
-
78751644734
-
Paneth cells constitute the niche for Lgr5 stem cells in intestinal crypts
-
T. Sato, J.H. van Es, H.J. Snippert, D.E. Stange, R.G. Vries, M. van den Born, N. Barker, N.F. Shroyer, M. van de Wetering, and H. Clevers Paneth cells constitute the niche for Lgr5 stem cells in intestinal crypts Nature 469 2011 415 418
-
(2011)
Nature
, vol.469
, pp. 415-418
-
-
Sato, T.1
Van Es, J.H.2
Snippert, H.J.3
Stange, D.E.4
Vries, R.G.5
Van Den Born, M.6
Barker, N.7
Shroyer, N.F.8
Van De Wetering, M.9
Clevers, H.10
-
42
-
-
0026581936
-
RAG-2-deficient mice lack mature lymphocytes owing to inability to initiate V(D)J rearrangement
-
Y. Shinkai, G. Rathbun, K.P. Lam, E.M. Oltz, V. Stewart, M. Mendelsohn, J. Charron, M. Datta, F. Young, and A.M. Stall et al. RAG-2-deficient mice lack mature lymphocytes owing to inability to initiate V(D)J rearrangement Cell 68 1992 855 867
-
(1992)
Cell
, vol.68
, pp. 855-867
-
-
Shinkai, Y.1
Rathbun, G.2
Lam, K.P.3
Oltz, E.M.4
Stewart, V.5
Mendelsohn, M.6
Charron, J.7
Datta, M.8
Young, F.9
Stall, A.M.10
-
43
-
-
26944474424
-
Gfi1 functions downstream of Math1 to control intestinal secretory cell subtype allocation and differentiation
-
N.F. Shroyer, D. Wallis, K.J.T. Venken, H.J. Bellen, and H.Y. Zoghbi Gfi1 functions downstream of Math1 to control intestinal secretory cell subtype allocation and differentiation Genes Dev. 19 2005 2412 2417
-
(2005)
Genes Dev.
, vol.19
, pp. 2412-2417
-
-
Shroyer, N.F.1
Wallis, D.2
Venken, K.J.T.3
Bellen, H.J.4
Zoghbi, H.Y.5
-
44
-
-
3042856262
-
Cre reporter strains produced by targeted insertion of EYFP and ECFP into the ROSA26 locus
-
S. Srinivas, T. Watanabe, C.S. Lin, C.M. William, Y. Tanabe, T.M. Jessell, and F. Costantini Cre reporter strains produced by targeted insertion of EYFP and ECFP into the ROSA26 locus BMC Dev. Biol. 1 2001 4
-
(2001)
BMC Dev. Biol.
, vol.1
, pp. 4
-
-
Srinivas, S.1
Watanabe, T.2
Lin, C.S.3
William, C.M.4
Tanabe, Y.5
Jessell, T.M.6
Costantini, F.7
-
45
-
-
20244364236
-
Wnt signalling induces maturation of Paneth cells in intestinal crypts
-
J.H. van Es, P. Jay, A. Gregorieff, M.E. van Gijn, S. Jonkheer, P. Hatzis, A. Thiele, M. van den Born, H. Begthel, and T. Brabletz et al. Wnt signalling induces maturation of Paneth cells in intestinal crypts Nat. Cell Biol. 7 2005 381 386
-
(2005)
Nat. Cell Biol.
, vol.7
, pp. 381-386
-
-
Van Es, J.H.1
Jay, P.2
Gregorieff, A.3
Van Gijn, M.E.4
Jonkheer, S.5
Hatzis, P.6
Thiele, A.7
Van Den Born, M.8
Begthel, H.9
Brabletz, T.10
-
46
-
-
84861372662
-
A critical role for the Wnt effector Tcf4 in adult intestinal homeostatic self-renewal
-
J.H. van Es, A. Haegebarth, P. Kujala, S. Itzkovitz, B.K. Koo, S.F. Boj, J. Korving, M. van den Born, A. van Oudenaarden, S. Robine, and H. Clevers A critical role for the Wnt effector Tcf4 in adult intestinal homeostatic self-renewal Mol. Cell. Biol. 32 2012 1918 1927
-
(2012)
Mol. Cell. Biol.
, vol.32
, pp. 1918-1927
-
-
Van Es, J.H.1
Haegebarth, A.2
Kujala, P.3
Itzkovitz, S.4
Koo, B.K.5
Boj, S.F.6
Korving, J.7
Van Den Born, M.8
Van Oudenaarden, A.9
Robine, S.10
Clevers, H.11
-
47
-
-
34347341670
-
Mutations in X-linked PORCN, a putative regulator of Wnt signaling, cause focal dermal hypoplasia
-
X. Wang, V. Reid Sutton, J. Omar Peraza-Llanes, Z. Yu, R. Rosetta, Y.-C. Kou, T.N. Eble, A. Patel, C. Thaller, P. Fang, and I.B. Van den Veyver Mutations in X-linked PORCN, a putative regulator of Wnt signaling, cause focal dermal hypoplasia Nat. Genet. 39 2007 836 838
-
(2007)
Nat. Genet.
, vol.39
, pp. 836-838
-
-
Wang, X.1
Reid Sutton, V.2
Omar Peraza-Llanes, J.3
Yu, Z.4
Rosetta, R.5
Kou, Y.-C.6
Eble, T.N.7
Patel, A.8
Thaller, C.9
Fang, P.10
Van Den Veyver, I.B.11
-
48
-
-
38049017120
-
G12-G13-LARG-mediated signaling in vascular smooth muscle is required for salt-induced hypertension
-
A. Wirth, Z. Benyó, M. Lukasova, B. Leutgeb, N. Wettschureck, S. Gorbey, P. Örsy, B. Horváth, C. Maser-Gluth, and E. Greiner et al. G12-G13-LARG-mediated signaling in vascular smooth muscle is required for salt-induced hypertension Nat. Med. 14 2008 64 68
-
(2008)
Nat. Med.
, vol.14
, pp. 64-68
-
-
Wirth, A.1
Benyó, Z.2
Lukasova, M.3
Leutgeb, B.4
Wettschureck, N.5
Gorbey, S.6
Örsy, P.7
Horváth, B.8
Maser-Gluth, C.9
Greiner, E.10
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