Involvement and targeted intervention of dysregulated hedgehog signaling in osteosarcoma

Cancer

Volumn 120, Issue 4, 2014, Pages 537-547

  Lo, Winnie W ^a   Wunder, Jay S ^b,c   Dickson, Brendan C ^a,c   Campbell, Veronica ^d   McGovern, Karen ^d   Alman, Benjamin A ^a   Andrulis, Irene L ^a,e  

^a UNIVERSITY OF TORONTO   (Canada)

^b MOUNT SINAI HOSPITAL   (Canada)

^c MOUNT SINAI HOSPITAL   (Canada)

^d Infinity Pharmaceuticals Inc   (United States)

^e HOSPITAL FOR SICK CHILDREN   (Canada)

Author keywords

hedgehog signaling; IPI 926; ligand dependent; microenvironment; osteosarcoma

Indexed keywords

HEDGEHOG SIGNALING; IPI-926; LIGAND-DEPENDENT; MICROENVIRONMENT; OSTEOSARCOMA;

ADOLESCENT; ADULT; ANTINEOPLASTIC AGENTS; BONE NEOPLASMS; CELL LINE, TUMOR; CELL PROLIFERATION; CHILD; FEMALE; HEDGEHOG PROTEINS; HUMANS; KRUPPEL-LIKE TRANSCRIPTION FACTORS; MALE; MOLECULAR TARGETED THERAPY; NUCLEAR PROTEINS; OSTEOSARCOMA; RECEPTORS, G-PROTEIN-COUPLED; SIGNAL TRANSDUCTION; TRANSCRIPTION FACTORS; VERATRUM ALKALOIDS; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 84893747723     PISSN: 0008543X     EISSN: 10970142     Source Type: Journal    
DOI: 10.1002/cncr.28439     Document Type: Article

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