메뉴 건너뛰기




Volumn 224, Issue 2, 2011, Pages 169-179

Role of GLI2 in the growth of human osteosarcoma

Author keywords

cell cycle; GLI2; Hedgehog; osteosarcoma

Indexed keywords

CYCLIN D1; CYCLIN DEPENDENT KINASE INHIBITOR 1; RETINOBLASTOMA PROTEIN; S PHASE KINASE ASSOCIATED PROTEIN 2; TRANSCRIPTION FACTOR GLI2;

EID: 79955821961     PISSN: 00223417     EISSN: 10969896     Source Type: Journal    
DOI: 10.1002/path.2880     Document Type: Article
Times cited : (61)

References (53)
  • 1
    • 0020386387 scopus 로고
    • Osteosarcoma
    • Sweetnam R,. Osteosarcoma. Br J Hosp Med 1982; 28: 112,116-121.
    • (1982) Br J Hosp Med , vol.28 , pp. 112
    • Sweetnam, R.1
  • 3
    • 68849120336 scopus 로고    scopus 로고
    • Primary osteogenic sarcoma with pulmonary metastasis: Clinical results and prognostic factors in 91 patients
    • Wu PK, Chen WM, Chen CF, et al., Primary osteogenic sarcoma with pulmonary metastasis: clinical results and prognostic factors in 91 patients. Japan J Clin Oncol 2009; 39: 514-522.
    • (2009) Japan J Clin Oncol , vol.39 , pp. 514-522
    • Wu, P.K.1    Chen, W.M.2    Chen, C.F.3
  • 4
    • 68849109737 scopus 로고    scopus 로고
    • Multi-institutional phase II study of neoadjuvant chemotherapy for osteosarcoma (NECO study) in Japan: NECO-93J and NECO-95J
    • Iwamoto Y, Tanaka K, Isu K, et al., Multi-institutional phase II study of neoadjuvant chemotherapy for osteosarcoma (NECO study) in Japan: NECO-93J and NECO-95J. J Orthop Sci 2009; 14: 397-404.
    • (2009) J Orthop Sci , vol.14 , pp. 397-404
    • Iwamoto, Y.1    Tanaka, K.2    Isu, K.3
  • 7
    • 0025304297 scopus 로고
    • Frequent inactivation of the retinoblastoma anti-oncogene is restricted to a subset of human tumor cells
    • Horowitz JM, Park SH, Bogenmann E, et al., Frequent inactivation of the retinoblastoma anti-oncogene is restricted to a subset of human tumor cells. Proc Natl Acad Sci USA 1990; 87: 2775-2779.
    • (1990) Proc Natl Acad Sci USA , vol.87 , pp. 2775-2779
    • Horowitz, J.M.1    Park, S.H.2    Bogenmann, E.3
  • 8
    • 0035577854 scopus 로고    scopus 로고
    • Hedgehog signaling in animal development: Paradigms and principles
    • DOI 10.1101/gad.938601
    • Ingham PW, McMahon AP,. Hedgehog signaling in animal development: paradigms and principles. Genes Dev 2001; 15: 3059-3087. (Pubitemid 33115673)
    • (2001) Genes and Development , vol.15 , Issue.23 , pp. 3059-3087
    • Ingham, P.W.1    McMahon, A.P.2
  • 9
    • 0036559186 scopus 로고    scopus 로고
    • Gli and hedgehog in cancer: Tumours, embryos and stem cells
    • Ruiz i Altaba A, Sanchez P, Dahmane N,. Gli and hedgehog in cancer: tumours, embryos and stem cells. Nat Rev 2002; 2: 361-372. (Pubitemid 37328949)
    • (2002) Nature Reviews Cancer , vol.2 , Issue.5 , pp. 361-372
    • Ruiz I Altaba, A.1    Sanchez, P.2    Dahmane, N.3
  • 10
    • 2942738996 scopus 로고    scopus 로고
    • The hedgehog response network: Sensors, switches, and routers
    • DOI 10.1126/science.1098020
    • Lum L, Beachy PA,. The Hedgehog response network: sensors, switches, and routers. Science (NY) 2004; 304: 1755-1759. (Pubitemid 38787882)
    • (2004) Science , vol.304 , Issue.5678 , pp. 1755-1759
    • Lum, L.1    Beachy, P.A.2
  • 11
    • 1842664354 scopus 로고    scopus 로고
    • Hedgehog: An unusual signal transducer
    • DOI 10.1002/bies.20007
    • Bijlsma MF, Spek CA, Peppelenbosch MP,. Hedgehog: an unusual signal transducer. Bioessays 2004; 26: 387-394. (Pubitemid 38461619)
    • (2004) BioEssays , vol.26 , Issue.4 , pp. 387-394
    • Bijlsma, M.F.1    Spek, C.A.2    Peppelenbosch, M.P.3
  • 12
    • 0031855859 scopus 로고    scopus 로고
    • Diminished Sonic hedgehog signaling and lack of floor plate differentiation in Gli2 mutant mice
    • Ding Q, Motoyama J, Gasca S, et al., Diminished sonic hedgehog signaling and lack of floor plate differentiation in Gli2 mutant mice. Development (Camb UK) 1998; 125: 2533-2543. (Pubitemid 28396152)
    • (1998) Development , vol.125 , Issue.14 , pp. 2533-2543
    • Ding, Q.1    Motoyama, J.2    Gasca, S.3    Mo, R.4    Sasaki, H.5    Rossant, J.6    Hui, C.-C.7
  • 13
    • 34848901657 scopus 로고    scopus 로고
    • The Gli code: An information nexus regulating cell fate, stemness and cancer
    • DOI 10.1016/j.tcb.2007.06.007, PII S0962892407001717
    • Ruiz i Altaba A, Mas C, Stecca B,. The Gli code: an information nexus regulating cell fate, stemness and cancer. Trends Cell Biol 2007; 17: 438-447. (Pubitemid 47505310)
    • (2007) Trends in Cell Biology , vol.17 , Issue.9 , pp. 438-447
    • Ruiz I Altaba, A.1    Mas, C.2    Stecca, B.3
  • 14
    • 69449095008 scopus 로고    scopus 로고
    • Bone repair by transplantation of hTERT-immortalized human mesenchymal stem cells in mice
    • Nakahara H, Misawa H, Hayashi T, et al., Bone repair by transplantation of hTERT-immortalized human mesenchymal stem cells in mice. Transplantation 2009; 88: 346-353.
    • (2009) Transplantation , vol.88 , pp. 346-353
    • Nakahara, H.1    Misawa, H.2    Hayashi, T.3
  • 15
    • 77749333021 scopus 로고    scopus 로고
    • Up-regulation of Notch pathway molecules in oral squamous cell carcinoma
    • Hijioka H, Setoguchi T, Miyawaki A, et al., Up-regulation of Notch pathway molecules in oral squamous cell carcinoma. Int J Oncol 2010; 36: 817-822.
    • (2010) Int J Oncol , vol.36 , pp. 817-822
    • Hijioka, H.1    Setoguchi, T.2    Miyawaki, A.3
  • 16
    • 71649083910 scopus 로고    scopus 로고
    • Tumour formation by single fibroblast growth factor receptor 3-positive rhabdomyosarcoma-initiating cells
    • Hirotsu M, Setoguchi T, Matsunoshita Y, et al., Tumour formation by single fibroblast growth factor receptor 3-positive rhabdomyosarcoma-initiating cells. Br J Cancer 2009; 101: 2030-2037.
    • (2009) Br J Cancer , vol.101 , pp. 2030-2037
    • Hirotsu, M.1    Setoguchi, T.2    Matsunoshita, Y.3
  • 17
    • 0030891148 scopus 로고    scopus 로고
    • A binding site for Gli proteins is essential for HNF-3β floor plate enhancer activity in transgenics and can respond to Shh in vitro
    • Sasaki H, Hui C, Nakafuku M, et al., A binding site for Gli proteins is essential for HNF-3β floor plate enhancer activity in transgenics and can respond to Shh in vitro. Development (Camb, UK) 1997; 124: 1313-1322. (Pubitemid 27190104)
    • (1997) Development , vol.124 , Issue.7 , pp. 1313-1322
    • Sasaki, H.1    Hui, C.-C.2    Nakafuku, M.3    Kondoh, H.4
  • 18
    • 0032848136 scopus 로고    scopus 로고
    • Regulation of Gli2 and Gli3 activities by an amino-terminal repression domain: Implication of Gli2 and Gli3 as primary mediators of Shh signaling
    • Sasaki H, Nishizaki Y, Hui C, et al., Regulation of Gli2 and Gli3 activities by an amino-terminal repression domain: implication of Gli2 and Gli3 as primary mediators of Shh signaling. Development (Camb, UK) 1999; 126: 3915-3924. (Pubitemid 29440488)
    • (1999) Development , vol.126 , Issue.17 , pp. 3915-3924
    • Sasaki, H.1    Nishizaki, Y.2    Hui, C.-C.3    Nakafuku, M.4    Kondoh, H.5
  • 19
    • 70349303196 scopus 로고    scopus 로고
    • Retinal astrocyte differentiation mediated by leukemia inhibitory factor in cooperation with bone morphogenetic protein 2
    • Fukushima M, Setoguchi T, Komiya S, et al., Retinal astrocyte differentiation mediated by leukemia inhibitory factor in cooperation with bone morphogenetic protein 2. Int J Dev Neurosci 2009; 27: 685-690.
    • (2009) Int J Dev Neurosci , vol.27 , pp. 685-690
    • Fukushima, M.1    Setoguchi, T.2    Komiya, S.3
  • 20
    • 77349122071 scopus 로고    scopus 로고
    • The knock-down of over-expressed EZH2 and BMI-1 does not prevent osteosarcoma growth
    • Sasaki H, Setoguchi T, Matsunoshita Y, et al., The knock-down of over-expressed EZH2 and BMI-1 does not prevent osteosarcoma growth. Oncology Rep 2010; 23: 677-684.
    • (2010) Oncology Rep , vol.23 , pp. 677-684
    • Sasaki, H.1    Setoguchi, T.2    Matsunoshita, Y.3
  • 21
    • 76849102604 scopus 로고    scopus 로고
    • Smoothened as a new therapeutic target for human osteosarcoma
    • Hirotsu M, Setoguchi T, Sasaki H, et al., Smoothened as a new therapeutic target for human osteosarcoma. Mol Cancer 2010; 9: 5.
    • (2010) Mol Cancer , vol.9 , pp. 5
    • Hirotsu, M.1    Setoguchi, T.2    Sasaki, H.3
  • 23
    • 50649112829 scopus 로고    scopus 로고
    • Osteosarcoma development and stem cell differentiation
    • Tang N, Song WX, Luo J, et al., Osteosarcoma development and stem cell differentiation. Clin Orthop Rel Res 2008; 466: 2114-2130.
    • (2008) Clin Orthop Rel Res , vol.466 , pp. 2114-2130
    • Tang, N.1    Song, W.X.2    Luo, J.3
  • 24
    • 26444577884 scopus 로고    scopus 로고
    • A previously unidentified amino-terminal domain regulates transcriptional activity of wild-type and disease-associated human GLI2
    • DOI 10.1093/hmg/ddi222
    • Roessler E, Ermilov AN, Grange DK, et al., A previously unidentified amino-terminal domain regulates transcriptional activity of wild-type and disease-associated human GLI2. Hum Mol Genet 2005; 14: 2181-2188. (Pubitemid 41418017)
    • (2005) Human Molecular Genetics , vol.14 , Issue.15 , pp. 2181-2188
    • Roessler, E.1    Ermilov, A.N.2    Grange, D.K.3    Wang, A.4    Grachtchouk, M.5    Dlugosz, A.A.6    Muenke, M.7
  • 25
    • 0035942736 scopus 로고    scopus 로고
    • Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells
    • DOI 10.1038/35078107
    • Elbashir SM, Harborth J, Lendeckel W, et al., Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells. Nature 2001; 411: 494-498. (Pubitemid 32494397)
    • (2001) Nature , vol.411 , Issue.6836 , pp. 494-498
    • Elbashir, S.M.1    Harborth, J.2    Lendeckel, W.3    Yalcin, A.4    Weber, K.5    Tuschl, T.6
  • 26
    • 77951132901 scopus 로고    scopus 로고
    • Evidence of RNAi in humans from systemically administered siRNA via targeted nanoparticles
    • Davis ME, Zuckerman JE, Choi CH, et al., Evidence of RNAi in humans from systemically administered siRNA via targeted nanoparticles. Nature 2010; 464: 1067-1070.
    • (2010) Nature , vol.464 , pp. 1067-1070
    • Davis, M.E.1    Zuckerman, J.E.2    Choi, C.H.3
  • 27
    • 77956345219 scopus 로고    scopus 로고
    • Inhibition of GLI, but not Smoothened, induces apoptosis in chronic lymphocytic leukemia cells
    • Desch P, Asslaber D, Kern D, et al., Inhibition of GLI, but not Smoothened, induces apoptosis in chronic lymphocytic leukemia cells. Oncogene 2010; 29: 4885-4895.
    • (2010) Oncogene , vol.29 , pp. 4885-4895
    • Desch, P.1    Asslaber, D.2    Kern, D.3
  • 29
    • 15444376392 scopus 로고    scopus 로고
    • Comparing the genetic changes detected in the primary and secondary tumor sites of ovarian cancer using comparative genomic hybridization
    • DOI 10.1111/j.1525-1438.2005.15213.x
    • Fishman A, Shalom-Paz E, Fejgin M, et al., Comparing the genetic changes detected in the primary and secondary tumor sites of ovarian cancer using comparative genomic hybridization. Int J Gynecol Cancer 2005; 15: 261-266. (Pubitemid 40396962)
    • (2005) International Journal of Gynecological Cancer , vol.15 , Issue.2 , pp. 261-266
    • Fishman, A.1    Shalom-Paz, E.2    Fejgin, M.3    Gaber, E.4    Altaras, M.5    Amiel, A.6
  • 30
    • 16644396279 scopus 로고    scopus 로고
    • Two subtypes of mucinous colorectal carcinoma characterized by laser scanning cytometry and comparative genomic hybridization
    • Liu XP, Sato T, Oga A, et al., Two subtypes of mucinous colorectal carcinoma characterized by laser scanning cytometry and comparative genomic hybridization. Int J Oncol 2004; 25: 615-621.
    • (2004) Int J Oncol , vol.25 , pp. 615-621
    • Liu, X.P.1    Sato, T.2    Oga, A.3
  • 32
    • 0033579870 scopus 로고    scopus 로고
    • CDK4 gene amplification in osteosarcoma: reciprocal relationship with INK4A gene alterations and mapping of 12q13 amplicons.
    • Wei G, Lonardo F, Ueda T, et al., CDK4 gene amplification in osteosarcoma: reciprocal relationship with INK4A gene alterations and mapping of 12q13 amplicons. Int J Cancer 1999; 80: 199-204.
    • (1999) Int J Cancer , vol.80 , pp. 199-204
    • Wei, G.1    Lonardo, F.2    Ueda, T.3
  • 35
    • 33751549095 scopus 로고    scopus 로고
    • Targeting the Hedgehog pathway in cancer
    • DOI 10.1038/nrd2086, PII NRD2086
    • Rubin LL, de Sauvage FJ,. Targeting the Hedgehog pathway in cancer. Nat Rev Drug Discov 2006; 5: 1026-1033. (Pubitemid 44835129)
    • (2006) Nature Reviews Drug Discovery , vol.5 , Issue.12 , pp. 1026-1033
    • Rubin, L.L.1    De Sauvage, F.J.2
  • 36
    • 33747875881 scopus 로고    scopus 로고
    • Recent advances in understanding extrinsic control of hematopoietic stem cell fate
    • DOI 10.1097/01.moh.0000231420.92782.8f, PII 0006275220060700000007
    • Ross J, Li L,. Recent advances in understanding extrinsic control of hematopoietic stem cell fate. Curr Opin Hematol 2006; 13: 237-242. (Pubitemid 44288899)
    • (2006) Current Opinion in Hematology , vol.13 , Issue.4 , pp. 237-242
    • Ross, J.1    Li, L.2
  • 37
    • 67349182923 scopus 로고    scopus 로고
    • Inhibition of Notch pathway prevents osteosarcoma growth by cell cycle regulation
    • Tanaka M, Setoguchi T, Hirotsu M, et al., Inhibition of Notch pathway prevents osteosarcoma growth by cell cycle regulation. Br J Cancer 2009; 100: 1957-1965.
    • (2009) Br J Cancer , vol.100 , pp. 1957-1965
    • Tanaka, M.1    Setoguchi, T.2    Hirotsu, M.3
  • 38
    • 63149124772 scopus 로고    scopus 로고
    • Hedgehog signaling is restricted to the stromal compartment during pancreatic carcinogenesis
    • Tian H, Callahan CA, DuPree KJ, et al., Hedgehog signaling is restricted to the stromal compartment during pancreatic carcinogenesis. Proc Natl Acad Sci USA 2009; 106: 4254-4259.
    • (2009) Proc Natl Acad Sci USA , vol.106 , pp. 4254-4259
    • Tian, H.1    Callahan, C.A.2    Dupree, K.J.3
  • 39
    • 52149119128 scopus 로고    scopus 로고
    • A paracrine requirement for hedgehog signalling in cancer
    • Yauch RL, Gould SE, Scales SJ, et al., A paracrine requirement for hedgehog signalling in cancer. Nature 2008; 455: 406-410.
    • (2008) Nature , vol.455 , pp. 406-410
    • Yauch, R.L.1    Gould, S.E.2    Scales, S.J.3
  • 41
    • 65549154968 scopus 로고    scopus 로고
    • Sonic hedgehog signaling pathway is activated in ALK-positive anaplastic large cell lymphoma
    • Singh RR, Cho-Vega JH, Davuluri Y, et al., Sonic hedgehog signaling pathway is activated in ALK-positive anaplastic large cell lymphoma. Cancer Res 2009; 69: 2550-2558.
    • (2009) Cancer Res , vol.69 , pp. 2550-2558
    • Singh, R.R.1    Cho-Vega, J.H.2    Davuluri, Y.3
  • 42
    • 39449090395 scopus 로고    scopus 로고
    • Stroma-initiated Hedgehog signaling takes center stage in B-cell lymphoma
    • DOI 10.1158/0008-5472.CAN-07-5500
    • Lindemann RK,. Stroma-initiated hedgehog signaling takes center stage in B-cell lymphoma. Cancer Res 2008; 68: 961-964. (Pubitemid 351272211)
    • (2008) Cancer Research , vol.68 , Issue.4 , pp. 961-964
    • Lindemann, R.K.1
  • 43
    • 69949136621 scopus 로고    scopus 로고
    • Primary cilia can both mediate and suppress Hedgehog pathway-dependent tumorigenesis
    • Wong SY, Seol AD, So PL, et al., Primary cilia can both mediate and suppress Hedgehog pathway-dependent tumorigenesis. Nat Med 2009; 15: 1055-1061.
    • (2009) Nat Med , vol.15 , pp. 1055-1061
    • Wong, S.Y.1    Seol, A.D.2    So, P.L.3
  • 44
    • 50649118068 scopus 로고    scopus 로고
    • Expansion of Bcr-Abl-positive leukemic stem cells is dependent on Hedgehog pathway activation
    • Dierks C, Beigi R, Guo GR, et al., Expansion of Bcr-Abl-positive leukemic stem cells is dependent on Hedgehog pathway activation. Cancer Cell 2008; 14: 238-249.
    • (2008) Cancer Cell , vol.14 , pp. 238-249
    • Dierks, C.1    Beigi, R.2    Guo, G.R.3
  • 45
    • 33646045010 scopus 로고    scopus 로고
    • Stem cells and cancer: Two faces of Eve
    • Clarke MF, Fuller M,. Stem cells and cancer: two faces of Eve. Cell 2006; 124: 1111-1115.
    • (2006) Cell , vol.124 , pp. 1111-1115
    • Clarke, M.F.1    Fuller, M.2
  • 46
    • 70349941243 scopus 로고    scopus 로고
    • Side population cells have the characteristics of cancer stem-like cells/cancer-initiating cells in bone sarcomas
    • Murase M, Kano M, Tsukahara T, et al., Side population cells have the characteristics of cancer stem-like cells/cancer-initiating cells in bone sarcomas. Br J Cancer 2009; 101: 1425-1432.
    • (2009) Br J Cancer , vol.101 , pp. 1425-1432
    • Murase, M.1    Kano, M.2    Tsukahara, T.3
  • 47
    • 9244221172 scopus 로고    scopus 로고
    • Tissue repair and stem cell renewal in carcinogenesis
    • DOI 10.1038/nature03100
    • Beachy PA, Karhadkar SS, Berman DM,. Tissue repair and stem cell renewal in carcinogenesis. Nature 2004; 432: 324-331. (Pubitemid 39551660)
    • (2004) Nature , vol.432 , Issue.7015 , pp. 324-331
    • Beachy, P.A.1    Karhadkar, S.S.2    Berman, D.M.3
  • 49
    • 64749091867 scopus 로고    scopus 로고
    • Hedgehog signalling is essential for maintenance of cancer stem cells in myeloid leukaemia
    • Zhao C, Chen A, Jamieson CH, et al., Hedgehog signalling is essential for maintenance of cancer stem cells in myeloid leukaemia. Nature 2009; 458: 776-779.
    • (2009) Nature , vol.458 , pp. 776-779
    • Zhao, C.1    Chen, A.2    Jamieson, C.H.3
  • 51
    • 65949112714 scopus 로고    scopus 로고
    • Aldehyde dehydrogenase 1 is a marker for normal and malignant human colonic stem cells (SC) and tracks SC overpopulation during colon tumorigenesis
    • Huang EH, Hynes MJ, Zhang T, et al., Aldehyde dehydrogenase 1 is a marker for normal and malignant human colonic stem cells (SC) and tracks SC overpopulation during colon tumorigenesis. Cancer Res 2009; 69: 3382-3389.
    • (2009) Cancer Res , vol.69 , pp. 3382-3389
    • Huang, E.H.1    Hynes, M.J.2    Zhang, T.3
  • 52
    • 34250732230 scopus 로고    scopus 로고
    • Aldehyde dehydrogenase activity in leukemic blasts defines a subgroup of acute myeloid leukemia with adverse prognosis and superior NOD/SCID engrafting potential
    • DOI 10.1038/sj.leu.2404721, PII 2404721
    • Cheung AM, Wan TS, Leung JC, et al., Aldehyde dehydrogenase activity in leukemic blasts defines a subgroup of acute myeloid leukemia with adverse prognosis and superior NOD/SCID engrafting potential. Leukemia 2007; 21: 1423-1430. (Pubitemid 46965282)
    • (2007) Leukemia , vol.21 , Issue.7 , pp. 1423-1430
    • Cheung, A.M.S.1    Wan, T.S.K.2    Leung, J.C.K.3    Chan, L.Y.Y.4    Huang, H.5    Kwong, Y.L.6    Liang, R.7    Leung, A.Y.H.8
  • 53
    • 78649580167 scopus 로고    scopus 로고
    • Prospective identification of tumorigenic osteosarcoma cancer stem cells in OS99-1 cells based on high aldehyde dehydrogenase activity
    • Wang L, Park P, Zhang H, et al., Prospective identification of tumorigenic osteosarcoma cancer stem cells in OS99-1 cells based on high aldehyde dehydrogenase activity. Int J Cancer 2011; 128: 294-303.
    • (2011) Int J Cancer , vol.128 , pp. 294-303
    • Wang, L.1    Park, P.2    Zhang, H.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.