Targeting endothelial junctional adhesion molecule-A/ EPAC/ Rap-1 axis as a novel strategy to increase stem cell engraftment in dystrophic muscles

EMBO Molecular Medicine

Volumn 6, Issue 2, 2014, Pages 239-258

  Giannotta, Monica ^a   Benedetti, Sara ^b,c   Tedesco, Francesco Saverio ^b,c   Corada, Monica ^a   Trani, Marianna ^a   D'Antuono, Rocco ^a   Millet, Queensta ^b   Orsenigo, Fabrizio ^a   Gálvez, Beatriz G ^d   Cossu, Giulio ^b,c,e   Dejana, Elisabetta ^a,f  

^a FIRC INSTITUTE OF MOLECULAR ONCOLOGY   (Italy)

^b UNIVERSITY COLLEGE LONDON   (United Kingdom)

^c SAN RAFFAELE HOSPITAL   (Italy)

^d CENTRO NACIONAL DE INVESTIGACIONES CARDIOVASCULARES CNIC   (Spain)

^e UNIVERSITY OF MANCHESTER   (United Kingdom)

^f UNIVERSITY OF MILAN   (Italy)

Author keywords

Endothelial cells; Junctional adhesion molecule A; Muscular dystrophy; Stem cell therapies

Indexed keywords

ALPHA SARCOGLYCAN; ANTIPORTER; CD31 ANTIGEN; CD38 ANTIGEN; EPAC 1 PROTEIN; EPAC 2 PROTEIN; GGTI 298; JUNCTIONAL ADHESION MOLECULE A; RAP1 PROTEIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL ADHESION; CELL DIFFERENTIATION; CELL MIGRATION; CONTROLLED STUDY; DOWN REGULATION; ENDOTHELIUM; ENDOTHELIUM CELL; ENGRAFTMENT; GASTROCNEMIUS MUSCLE; GENE INACTIVATION; HISTOPATHOLOGY; HUMAN; HUMAN CELL; IMMUNOBLOTTING; IMMUNOFLUORESCENCE; IMMUNOPRECIPITATION; IN VITRO STUDY; INFLAMMATORY INFILTRATE; MACROPHAGE; MONOCYTE; MOUSE; MUSCLE INJURY; MUSCULAR DYSTROPHY; NONHUMAN; PRIORITY JOURNAL; SKELETAL MUSCLE; STEM CELL; STEM CELL TRANSPLANTATION;

ANIMALS; CARDIOTOXINS; CELL ADHESION MOLECULES; CELL MOVEMENT; ENDOTHELIAL CELLS; ENDOTHELIUM, VASCULAR; GUANINE NUCLEOTIDE EXCHANGE FACTORS; HUMANS; MICE; MUSCLE, SKELETAL; MUSCULAR DYSTROPHIES; RAP1 GTP-BINDING PROTEINS; RECEPTORS, CELL SURFACE; SARCOGLYCANS; SIGNAL TRANSDUCTION; STEM CELL TRANSPLANTATION; STEM CELLS;

EID: 84893734415     PISSN: 17574676     EISSN: 17574684     Source Type: Journal    
DOI: 10.1002/emmm.201302520     Document Type: Article

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