The presynaptic active zone protein RIM1α is critical for normal learning and memory

Neuron

Volumn 42, Issue 1, 2004, Pages 143-153

  Powell, Craig M ^a,b   Schoch, Susanne ^c,d   Monteggia, Lisa ^a   Barrot, Michel ^a   Matos, Maria F ^c   Feldmann, Nicole ^d   Südhof, Thomas C ^b,c   Nestler, Eric J ^a,c  

^a UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^b UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^c UNIVERSITY OF TEXAS AT DALLAS   (United States)

^d UNIVERSITY OF BONN   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

MEMBRANE PROTEIN; PROTEIN RIM1 ALPHA; RAB PROTEIN; SYNAPTOTAGMIN; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ANXIETY; ARTICLE; COORDINATION; FEMALE; GENE DELETION; LEARNING; LONG TERM POTENTIATION; MALE; MEMORY; MOUSE; MUTATION; NONHUMAN; PRIORITY JOURNAL; PROBABILITY;

ANIMALS; BEHAVIOR, ANIMAL; BLOTTING, WESTERN; BRAIN; CALCIUM-BINDING PROTEINS; CONDITIONING, CLASSICAL; FEAR; GTP-BINDING PROTEINS; IN SITU HYBRIDIZATION; LEARNING; MAZE LEARNING; MEMBRANE GLYCOPROTEINS; MEMORY; MICE; MICE, KNOCKOUT; MOTOR ACTIVITY; NERVE TISSUE PROTEINS; PSYCHOMOTOR PERFORMANCE; RAB3A GTP-BINDING PROTEIN; REACTION TIME; SPACE PERCEPTION; SPATIAL BEHAVIOR; SYNAPTOTAGMIN I; SYNAPTOTAGMINS; TIME FACTORS;

EID: 1842505509     PISSN: 08966273     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0896-6273(04)00146-1     Document Type: Article

References (36)

1. Augustin I., Rosenmund C., Sudhof T.C., Brose N. Munc13-1 is essential for fusion competence of glutamatergic synaptic vesicles. Nature. 400:1999;457-461.
2. Brose N., Rosenmund C., Rettig J. Regulation of transmitter release by Unc-13 and its homologues. Curr. Opin. Neurobiol. 10:2000;303-311.
3. Castillo P.E., Janz R., Sudhof T.C., Tzounopoulos T., Malenka R.C., Nicoll R.A. Rab3A is essential for mossy fibre long-term potentiation in the hippocampus. Nature. 388:1997;590-593.
4. Castillo P.E., Schoch S., Schmitz F., Sudhof T.C., Malenka R.C. RIM1alpha is required for presynaptic long-term potentiation. Nature. 415:2002;327-330.
5. Chapouthier G., Venault P. GABA-A receptor complex and memory processes. Curr. Top. Med. Chem. 2:2002;841-851.
6. Chen J., Sochivko D., Beck H., Marechal D., Wiestler O.D., Becker A.J. Activity-induced expression of common reference genes in individual CNS neurons. Lab. Invest. 81:2001;913-916.
7. Coppola T., Magnin-Luthi S., Perret-Menoud V., Gattesco S., Schiavo G., Regazzi R. Direct interaction of the Rab3 effector RIM with Ca2+ channels, SNAP-25, and synaptotagmin. J. Biol. Chem. 276:2001;32756-32762.
8. Dobrunz L.E., Garner C.C. Priming plasticity. Nature. 415:2002;277-278.
9. Fernandez-Chacon R., Sudhof T.C. Genetics of synaptic vesicle function. toward the complete functional anatomy of an organelle Annu. Rev. Physiol. 61:1999;753-776.
10. Fernandez-Chacon R., Konigstorfer A., Gerber S.H., Garcia J., Matos M.F., Stevens C.F., Brose N., Rizo J., Rosenmund C., Sudhof T.C. Synaptotagmin I functions as a calcium regulator of release probability. Nature. 410:2001;41-49.
11. Geppert M., Bolshakov V.Y., Siegelbaum S.A., Takei K., De Camilli P., Hammer R.E., Sudhof T.C. The role of Rab3A in neurotransmitter release. Nature. 369:1994;493-497.
12. Hensbroek R.A., Kamal A., Baars A.M., Verhage M., Spruijt B.M. Spatial, contextual and working memory are not affected by the absence of mossy fiber long-term potentiation and depression. Behav. Brain Res. 138:2003;215-223.
13. Huang Y.Y., Kandel E.R., Varshavsky L., Brandon E.P., Qi M., Idzerda R.L., McKnight G.S., Bourtchouladze R. A genetic test of the effects of mutations in PKA on mossy fiber LTP and its relation to spatial and contextual learning. Cell. 83:1995;1211-1222.
14. Laemmli U.K. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature. 227:1970;680-685.
15. LeDoux J.E. Emotion circuits in the brain. Annu. Rev. Neurosci. 23:2000;155-184.
16. Lipska B.K., Weinberger D.R. To model a psychiatric disorder in animals. schizophrenia as a reality test Neuropsychopharmacology. 23:2000;223-239.
17. Lonart G. RIM1. an edge for presynaptic plasticity Trends Neurosci. 25:2002;329-332.
18. Lonart G., Schoch S., Kaeser P.S., Larkin C.J., Sudhof T.C., Linden D.J. Phosphorylation of RIM1alpha by PKA triggers presynaptic long-term potentiation at cerebellar parallel fiber synapses. Cell. 115:2003;49-60.
19. Maren S. Neurobiology of Pavlovian fear conditioning. Annu. Rev. Neurosci. 24:2001;897-931.
20. Matilla A., Roberson E.D., Banfi S., Morales J., Armstrong D.L., Burright E.N., Orr H.T., Sweatt J.D., Zoghbi H.Y., Matzuk M.M. Mice lacking ataxin-1 display learning deficits and decreased hippocampal paired-pulse facilitation. J. Neurosci. 18:1998;5508-5516.
21. Matynia A., Kushner S.A., Silva A.J. Genetic approaches to molecular and cellular cognition. a focus on LTP and learning and memory Annu. Rev. Genet. 36:2002;687-720.
22. Mayford M., Kandel E.R. Genetic approaches to memory storage. Trends Genet. 15:1999;463-470.
23. Mellor J., Nicoll R.A. Hippocampal mossy fiber LTP is independent of postsynaptic calcium. Nat. Neurosci. 4:2001;125-126.
24. Nicoll R.A., Malenka R.C. Contrasting properties of two forms of long-term potentiation in the hippocampus. Nature. 377:1995;115-118.
25. Otto C., Kovalchuk Y., Wolfer D.P., Gass P., Martin M., Zuschratter W., Grone H.J., Kellendonk C., Tronche F., Maldonado R.et al. Impairment of mossy fiber long-term potentiation and associative learning in pituitary adenylate cyclase activating polypeptide type I receptor-deficient mice. J. Neurosci. 21:2001;5520-5527. a.
26. Otto C., Martin M., Paul Wolfer D., Lipp H., Maldonado R., Schutz G. Altered emotional behavior in PACAP-type-I-receptor-deficient mice. Brain Res. Mol. Brain Res. 92:2001;78-84. b.
27. Schoch S., Castillo P.E., Jo T., Mukherjee K., Geppert M., Wang Y., Schmitz F., Malenka R.C., Sudhof T.C. RIM1alpha forms a protein scaffold for regulating neurotransmitter release at the active zone. Nature. 415:2002;321-326.
28. Silva A.J., Rosahl T.W., Chapman P.F., Marowitz Z., Friedman E., Frankland P.W., Cestari V., Cioffi D., Sudhof T.C., Bourtchuladze R. Impaired learning in mice with abnormal short-lived plasticity. Curr. Biol. 6:1996;1509-1518.
29. Sweatt J.D. Mechanisms of Memory. 2003;Academic Press, San Diego, CA.
30. Tonegawa S., Nakazawa K., Wilson M.A. Genetic neuroscience of mammalian learning and memory. Philos. Trans. R. Soc. Lond. B Biol. Sci. 358:2003;787-795.
31. Towbin H., Staehelin T., Gordon J. Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets. procedure and some applications Proc. Natl. Acad. Sci. USA. 76:1979;4350-4354.
32. Villacres E.C., Wong S.T., Chavkin C., Storm D.R. Type I adenylyl cyclase mutant mice have impaired mossy fiber long-term potentiation. J. Neurosci. 18:1998;3186-3194.
33. Wang Y., Okamoto M., Schmitz F., Hofmann K., Sudhof T.C. Rim is a putative Rab3 effector in regulating synaptic-vesicle fusion. Nature. 388:1997;593-598.
34. Weisskopf M.G., Nicoll R.A. Presynaptic changes during mossy fibre LTP revealed by NMDA receptor-mediated synaptic responses. Nature. 376:1995;256-259.
35. Wu Z.L., Thomas S.A., Villacres E.C., Xia Z., Simmons M.L., Chavkin C., Palmiter R.D., Storm D.R. Altered behavior and long-term potentiation in type I adenylyl cyclase mutant mice. Proc. Natl. Acad. Sci. USA. 92:1995;220-224.
36. Yeckel M.F., Kapur A., Johnston D. Multiple forms of LTP in hippocampal CA3 neurons use a common postsynaptic mechanism. Nat. Neurosci. 2:1999;625-633.