The effect of side-chain functionality and hydrophobicity on the gene delivery capabilities of cationic helical polypeptides

Biomaterials

Volumn 35, Issue 10, 2014, Pages 3443-3454

  Zhang, Rujing ^a   Zheng, Nan ^a   Song, Ziyuan ^a   Yin, Lichen ^a   Cheng, Jianjun ^a  

^a University of Illinois at Urbana Champaign   (United States)

Author keywords

Helical polypeptide; Guanidine; Hydrophobicity; Non viral gene delivery; Structure function relationship

Indexed keywords

GUANIDINE; HELICAL POLYPEPTIDES; NON-VIRAL GENE DELIVERY; POLYPEPTIDE STRUCTURES; SIDE-CHAIN FUNCTIONALITIES; STRUCTURE PROPERTY RELATIONSHIPS; STRUCTURE-FUNCTION RELATIONSHIP; TRANSFECTION EFFICIENCY;

CHAINS; DESIGN; GENE TRANSFER; HYDROPHOBICITY; LIPOSOMES;

POLYPEPTIDES;

GUANIDINE; LIPOFECTAMINE; POLYPEPTIDE;

ARTICLE; CHANNEL GATING; CONTROLLED STUDY; CYTOTOXICITY; FEMALE; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; HYDROPHOBICITY; MEMBRANE; NONVIRAL GENE DELIVERY SYSTEM; PRIORITY JOURNAL; PROTEIN STRUCTURE; PROTEIN SYNTHESIS;

GUANIDINE; HYDROPHOBICITY; NON-VIRAL GENE DELIVERY; STRUCTURE-FUNCTION RELATIONSHIP; Α-HELICAL POLYPEPTIDE;

CATIONS; GENE TRANSFER TECHNIQUES; HYDROPHOBIC AND HYDROPHILIC INTERACTIONS; KINETICS; MAGNETIC RESONANCE SPECTROSCOPY; PEPTIDES;

EID: 84893706696     PISSN: 01429612     EISSN: 18785905     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2013.12.097     Document Type: Article

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