-
1
-
-
0034700141
-
The design, synthesis, and evaluation of molecules that enable or enhance cellular uptake: Peptoid molecular transporters
-
Wender, P. A.; Mitchell, D. J.; Pattabiraman, K.; Pelkey, E. T.; Steinman, L.; Rothbard, J. B. The design, synthesis, and evaluation of molecules that enable or enhance cellular uptake: Peptoid molecular transporters Proc. Natl. Acad. Sci. U.S.A. 2000, 97, 13003-13008
-
(2000)
Proc. Natl. Acad. Sci. U.S.A.
, vol.97
, pp. 13003-13008
-
-
Wender, P.A.1
Mitchell, D.J.2
Pattabiraman, K.3
Pelkey, E.T.4
Steinman, L.5
Rothbard, J.B.6
-
2
-
-
39149103400
-
The design of guanidinium-rich transporters and their internalization mechanisms
-
Wender, P. A.; Galliher, W. C.; Goun, E. A.; Jones, L. R.; Pillow, T. H. The design of guanidinium-rich transporters and their internalization mechanisms Adv. Drug Delivery Rev. 2008, 60, 452-472
-
(2008)
Adv. Drug Delivery Rev.
, vol.60
, pp. 452-472
-
-
Wender, P.A.1
Galliher, W.C.2
Goun, E.A.3
Jones, L.R.4
Pillow, T.H.5
-
4
-
-
84871725121
-
Vault nanoparticles engineered with the protein transduction domain, TAT48, enhances cellular uptake
-
Yang, J.; Srinivasan, A.; Sun, Y.; Mrazek, J.; Shu, Z.; Kickhoefer, V. A.; Rome, L. H. Vault nanoparticles engineered with the protein transduction domain, TAT48, enhances cellular uptake Integr. Biol. 2013, 5, 151-158
-
(2013)
Integr. Biol.
, vol.5
, pp. 151-158
-
-
Yang, J.1
Srinivasan, A.2
Sun, Y.3
Mrazek, J.4
Shu, Z.5
Kickhoefer, V.A.6
Rome, L.H.7
-
5
-
-
84865179842
-
A molecular method for the delivery of small molecules and proteins across the cell wall of algae using molecular transporters
-
Hyman, J. M.; Geihe, E. I.; Trantow, B. M.; Parvin, B.; Wender, P. A. A molecular method for the delivery of small molecules and proteins across the cell wall of algae using molecular transporters Proc. Natl. Acad. Sci. U.S.A. 2012, 109, 13225-13230
-
(2012)
Proc. Natl. Acad. Sci. U.S.A.
, vol.109
, pp. 13225-13230
-
-
Hyman, J.M.1
Geihe, E.I.2
Trantow, B.M.3
Parvin, B.4
Wender, P.A.5
-
6
-
-
56749179070
-
Peptide-mediated cellular uptake of cryptophane
-
Seward, G. K.; Wei, Q.; Dmochowski, I. J. Peptide-mediated cellular uptake of cryptophane Bioconjugate Chem. 2008, 19, 2129-2135
-
(2008)
Bioconjugate Chem.
, vol.19
, pp. 2129-2135
-
-
Seward, G.K.1
Wei, Q.2
Dmochowski, I.J.3
-
7
-
-
0035937124
-
Arginine-rich peptides: An abundant source membrane-permeable peptides having potential as carriers for intracellular protein delivery
-
Futaki, S.; Suzuki, T.; Ohashi, W.; Yagami, T.; Tanaka, S.; Ueda, K.; Sugiura, Y. Arginine-rich peptides: An abundant source membrane-permeable peptides having potential as carriers for intracellular protein delivery J. Biol. Chem. 2001, 276, 5836-5840
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 5836-5840
-
-
Futaki, S.1
Suzuki, T.2
Ohashi, W.3
Yagami, T.4
Tanaka, S.5
Ueda, K.6
Sugiura, Y.7
-
8
-
-
84862865685
-
Drug delivery trends in clinical trials and translational medicine: Growth in biologic molecule development and impact on rheumatoid arthritis, Crohn's disease, and colitis
-
Ho, R. J. Y.; Chien, J. Y. Drug delivery trends in clinical trials and translational medicine: Growth in biologic molecule development and impact on rheumatoid arthritis, Crohn's disease, and colitis J. Pharm. Sci. 2012, 101, 2668-2674
-
(2012)
J. Pharm. Sci.
, vol.101
, pp. 2668-2674
-
-
Ho, R.J.Y.1
Chien, J.Y.2
-
9
-
-
38949192863
-
Tat peptide-mediated intracellular delivery of pharmaceutical nanocarriers
-
DOI 10.1016/j.addr.2007.10.008, PII S0169409X0700289X
-
Torchilin, V. P. Tat peptide-mediated intracellular delivery of pharmaceutical nanocarriers Adv. Drug Delivery Rev. 2008, 60, 548-558 (Pubitemid 351215572)
-
(2008)
Advanced Drug Delivery Reviews
, vol.60
, Issue.4-5
, pp. 548-558
-
-
Torchilin, V.P.1
-
10
-
-
84859495444
-
-
Ed. Methods in Molecular Biology Series 683; Humana Press Inc. Totowa, NJ.
-
Cell-Penetrating Peptides: Methods and Protocols; Langel, U., Ed.; Methods in Molecular Biology Series 683; Humana Press Inc.: Totowa, NJ, 2011.
-
(2011)
Cell-Penetrating Peptides: Methods and Protocols
-
-
Langel, U.1
-
11
-
-
0024209811
-
Autonomous functional domains of chemically synthesized human immunodeficiency virus Tat trans-activator protein
-
Green, M. M.; Loewenstein, P. M. P. Autonomous functional domains of chemically synthesized human immunodeficiency virus Tat trans-activator protein Cell 1988, 55, 1179-1188
-
(1988)
Cell
, vol.55
, pp. 1179-1188
-
-
Green, M.M.1
Loewenstein, P.M.P.2
-
12
-
-
0024262589
-
Cellular uptake of the tat protein from human immunodeficiency virus
-
DOI 10.1016/0092-8674(88)90263-2
-
Frankel, A. D.; Pabo, C. O. Cellular uptake of the tat protein from human immunodeficiency virus Cell 1988, 55, 1189-1193 (Pubitemid 19020071)
-
(1988)
Cell
, vol.55
, Issue.6
, pp. 1189-1193
-
-
Frankel, A.D.1
Pabo, C.O.2
-
13
-
-
0030904245
-
A truncated HIV-1 Tat protein basic domain rapidly translocates through the plasma membrane and accumulates in the cell nucleus
-
DOI 10.1074/jbc.272.25.16010
-
Vivés, L.; Brodin, P.; Lebleu, B. A truncated HIV-1 Tat protein basic domain rapidly translocates through the plasma membrane and accumulates in the cell nucleus J. Biol. Chem. 1997, 272, 16010-16017 (Pubitemid 27265584)
-
(1997)
Journal of Biological Chemistry
, vol.272
, Issue.25
, pp. 16010-16017
-
-
Vives, E.1
Brodin, P.2
Lebleu, B.3
-
14
-
-
0033794501
-
Polyarginine enters cells more efficiently than other polycationic homopolymers
-
Mitchell, D. J.; Kim, D. T.; Steinman, L.; Fathman, C. G.; Rothbard, J. B. Polyarginine enters cells more efficiently than other polycationic homopolymers J. Peptide Res. 2000, 56, 318-325
-
(2000)
J. Peptide Res.
, vol.56
, pp. 318-325
-
-
Mitchell, D.J.1
Kim, D.T.2
Steinman, L.3
Fathman, C.G.4
Rothbard, J.B.5
-
15
-
-
3543051871
-
Role of membrane potential and hydrogen bonding in the mechanism of translocation of guanidinium-rich peptides into cells
-
DOI 10.1021/ja0482536
-
Rothbard, J. B.; Jessop, T. C.; Lewis, R. S.; Murray, B. A.; Wender, P. A. Role of membrane potential and hydrogen bonding in the mechanism of translocation of guanidinium-rich peptides into cells J. Am. Chem. Soc. 2004, 126, 9506-9507 (Pubitemid 39031015)
-
(2004)
Journal of the American Chemical Society
, vol.126
, Issue.31
, pp. 9506-9507
-
-
Rothbard, J.B.1
Jessop, T.C.2
Lewis, R.S.3
Murray, B.A.4
Wender, P.A.5
-
16
-
-
38949138457
-
Function-oriented synthesis, step economy, and drug design
-
Wender, P. A.; Verma, V. A.; Paxton, T. J.; Pillow, T. H. Function-oriented synthesis, step economy, and drug design Acc. Chem. Res. 2008, 41, 40-49
-
(2008)
Acc. Chem. Res.
, vol.41
, pp. 40-49
-
-
Wender, P.A.1
Verma, V.A.2
Paxton, T.J.3
Pillow, T.H.4
-
17
-
-
0033678653
-
Conjugation of arginine oligomers to cyclosporin A facilitates topical delivery and inhibition of inflammation
-
Rothbard, J. B.; Garlington, S.; Lin, Q.; Kirschberg, T.; Kreider, E.; McGrane, P. L.; Wender, P. A.; Khavari, P. A. Conjugation of arginine oligomers to cyclosporin A facilitates topical delivery and inhibition of inflammation Nat. Med. 2000, 6, 1253-1257
-
(2000)
Nat. Med.
, vol.6
, pp. 1253-1257
-
-
Rothbard, J.B.1
Garlington, S.2
Lin, Q.3
Kirschberg, T.4
Kreider, E.5
McGrane, P.L.6
Wender, P.A.7
Khavari, P.A.8
-
18
-
-
0033520487
-
In vivo protein transduction: Delivery of a biologically active protein into the mouse
-
DOI 10.1126/science.285.5433.1569
-
Schwarze, S. R.; Ho, A.; Vocero-Akbani, A.; Dowdy, S. F. In vivo protein transduction: Delivery of a biologically active protein into the mouse Science 1999, 285, 1569-1572 (Pubitemid 29420581)
-
(1999)
Science
, vol.285
, Issue.5433
, pp. 1569-1572
-
-
Schwarze, S.R.1
Ho, A.2
Vocero-Akbani, A.3
Dowdy, S.F.4
-
19
-
-
33646716870
-
Releasable luciferin-transporter conjugates: Tools for the real-time analysis of cellular uptake and release
-
Jones, L. R.; Goun, E. A.; Shinde, R.; Rothbard, J. B.; Contag, C. H.; Wender, P. A. Releasable luciferin-transporter conjugates: Tools for the real-time analysis of cellular uptake and release J. Am. Chem. Soc. 2006, 128, 6526-6527
-
(2006)
J. Am. Chem. Soc.
, vol.128
, pp. 6526-6527
-
-
Jones, L.R.1
Goun, E.A.2
Shinde, R.3
Rothbard, J.B.4
Contag, C.H.5
Wender, P.A.6
-
20
-
-
0035542854
-
7
-
DOI 10.1016/S1074-5521(01)00076-X, PII S107455210100076X
-
Chen, L.; Wright, L. R.; Chen, C. H.; Oliver, S. F.; Wender, P. A.; Mochly-Rosen, D. Molecular transporters for peptides: delivery of a cardioprotective εPKC agonist peptide into cells and intact ischemic heart using a transport system, R7 Chem. Biol. 2001, 8, 1123-1129 (Pubitemid 34029881)
-
(2001)
Chemistry and Biology
, vol.8
, Issue.12
, pp. 1123-1129
-
-
Chen, L.1
Wright, L.R.2
Chen, C.-H.3
Oliver, S.F.4
Wender, P.A.5
Mochly-Rosen, D.6
-
21
-
-
0037103242
-
Arginine-rich molecular transporters for drug delivery: Role of backbone spacing in cellular uptake
-
DOI 10.1021/jm0105676
-
Rothbard, J. B.; Kreider, E.; VanDeusen, C. L.; Wright, L.; Wylie, B. L.; Wender, P. A. Arginine-rich Molecular transporters for drug delivery: Role of backbone spacing in cellular uptake J. Med. Chem. 2002, 45, 3612-3618 (Pubitemid 34856101)
-
(2002)
Journal of Medicinal Chemistry
, vol.45
, Issue.17
, pp. 3612-3618
-
-
Rothbard, J.B.1
Kreider, E.2
VanDeusen, C.L.3
Wright, L.4
Wylie, B.L.5
Wender, P.A.6
-
22
-
-
0036523467
-
Cellular uptake studies with Beta-peptides
-
Rueping, M.; Mahajan, Y.; Sauer, M.; Seebach, D. Cellular uptake studies with Beta-peptides ChemBioChem 2002, 3, 257-259
-
(2002)
ChemBioChem
, vol.3
, pp. 257-259
-
-
Rueping, M.1
Mahajan, Y.2
Sauer, M.3
Seebach, D.4
-
23
-
-
0037160363
-
Translocation of a β-peptide across cell membranes
-
DOI 10.1021/ja017283v
-
Umezawa, N.; Gelman, M. A.; Haigis, M. C.; Raines, R. T.; Gellman, S. H. Translocation of a β-peptide across cell membranes J. Am. Chem. Soc. 2002, 124, 368-369 (Pubitemid 34084120)
-
(2002)
Journal of the American Chemical Society
, vol.124
, Issue.3
, pp. 368-369
-
-
Umezawa, N.1
Gelman, M.A.2
Haigis, M.C.3
Raines, R.T.4
Gellman, S.H.5
-
24
-
-
23944492106
-
Cell penetrating agents based on a polyproline helix scaffold
-
DOI 10.1021/ja052377g
-
Fillon, Y.A.; Anderson, J. P.; Chmielewski, J. Cell-penetrating agents based on a polyproline helix scaffold J. Am. Chem. Soc. 2005, 127, 11798-11803 (Pubitemid 41208765)
-
(2005)
Journal of the American Chemical Society
, vol.127
, Issue.33
, pp. 11798-11803
-
-
Fillon, Y.A.1
Anderson, J.P.2
Chmielewski, J.3
-
25
-
-
0037073171
-
Oligocarbamate molecular transporters: Design, synthesis, and biological evaluation of a new class of transporters for drug delivery
-
DOI 10.1021/ja0275109
-
Wender, P. A.; Rothbard, J. B.; Jessop, T. C.; Kreider, E. L.; Wylie, B. L. Oligocarbamate molecular transporters: Design, synthesis, and biological evaluation of a new class of transporters for drug delivery J. Am. Chem. Soc. 2002, 124, 13382-13383 (Pubitemid 35285905)
-
(2002)
Journal of the American Chemical Society
, vol.124
, Issue.45
, pp. 13382-13383
-
-
Wender, P.A.1
Rothbard, J.B.2
Jessop, T.C.3
Kreider, E.L.4
Wylie, B.L.5
-
26
-
-
33746191891
-
Design, synthesis, and membrane-translocation studies of inositol-based transporters
-
DOI 10.1002/anie.200600312
-
Maiti, K. K.; Jeon, O. Y.; Lee, W. S.; Kim, D. C.; Kim, K. T.; Takeuchi, T.; Futaki, S.; Chung, S. K. Design, synthesis, and membrane-translocation studies of inositol-based transporters Angew. Chem., Int. Ed. 2006, 45, 2907-2912 (Pubitemid 44099062)
-
(2006)
Angewandte Chemie - International Edition
, vol.45
, Issue.18
, pp. 2907-2912
-
-
Maiti, K.K.1
Jeon, O.-Y.2
Lee, W.S.3
Kim, D.-C.4
Kim, K.-T.5
Takeuchi, T.6
Futaki, S.7
Chung, S.-K.8
-
27
-
-
34547728730
-
Guanidine-containing molecular transporters: Sorbitol-based transporters show high intracellular selectivity toward mitochondria
-
DOI 10.1002/anie.200701346
-
Maiti, K. K.; Lee, W. S.; Takeuchi, T.; Watkins, C.; Fretz, M.; Kim, D. C.; Futaki, S.; Jones, A.; Kim, K. T.; Chung, S. K. Guanidine-containing molecular transporters: Sorbitol-based transporters show high intracellular selectivity toward mitochondria Angew. Chem., Int. Ed. 2007, 46, 5880-5884 (Pubitemid 47236461)
-
(2007)
Angewandte Chemie - International Edition
, vol.46
, Issue.31
, pp. 5880-5884
-
-
Maiti, K.K.1
Lee, W.S.2
Takeuchi, T.3
Watkins, C.4
Fretz, M.5
Kim, D.-C.6
Futaki, S.7
Jones, A.8
Kim, K.-T.9
Chung, S.-K.10
-
28
-
-
0037172801
-
Translocation of branched-chain arginine peptides through cell membranes: Flexibility in the spatial disposition of positive charges in membrane-permeable peptides
-
DOI 10.1021/bi0256173
-
Futaki, S.; Nakase, I.; Suzuki, T.; Zhang; Sugiura, Y. Translocation of branched-chain arginine peptides through cell membranes: Flexibility in the spatial disposition of positive charges in membrane-permeable peptides Biochemistry 2002, 41, 7925-7930 (Pubitemid 34655157)
-
(2002)
Biochemistry
, vol.41
, Issue.25
, pp. 7925-7930
-
-
Futaki, S.1
Nakase, I.2
Suzuki, T.3
Youjun, Z.4
Sugiura, Y.5
-
29
-
-
1542406433
-
Dendritic Oligoguanidines as Intracellular Translocators
-
DOI 10.1002/bip.10597
-
Chung, H. H.; Harms, G.; Min Seong, C.; Choi, B. H.; Min, C.; Taulane, J. P.; Goodman, M. Dendritic oligoguanidines as intracellular translocators Biopolym. Pept. Sci. 2004, 76, 83-96 (Pubitemid 38339099)
-
(2004)
Biopolymers - Peptide Science Section
, vol.76
, Issue.1
, pp. 83-96
-
-
Chung, H.-H.1
Harms, G.2
Seong, C.M.3
Choi, B.H.4
Min, C.5
Taulane, J.P.6
Goodman, M.7
-
30
-
-
27644470173
-
Dendrimeric molecular transporters: Synthesis and evaluation of tunable polyguanidino dendrimers that facilitate cellular uptake
-
DOI 10.1021/ol051496y
-
Wender, P. A.; Kreider, E.; Pelkey, E. T.; Rothbard, J.; VanDeusen, C. L. Dendritic molecular transporters: Synthesis and evaluation of tunable polyguanidino dendrimers that facilitate cellular uptake Org. Lett. 2005, 7, 4815-4818 (Pubitemid 41579870)
-
(2005)
Organic Letters
, vol.7
, Issue.22
, pp. 4815-4818
-
-
Wender, P.A.1
Kreider, E.2
Pelkey, E.T.3
Rothbard, J.4
VanDeusen, C.L.5
-
31
-
-
33947661931
-
Dendritic molecular transporters provide control of delivery to intracellular compartments
-
DOI 10.1021/bc060287a
-
Huang, K.; Voss, B.; Kumar, D.; Hamm, H. E.; Harth, E. Dendritic molecular transporters provide control of delivery to intracellular compartments Bioconjugate Chem. 2007, 18, 403-409 (Pubitemid 46493511)
-
(2007)
Bioconjugate Chemistry
, vol.18
, Issue.2
, pp. 403-409
-
-
Huang, K.1
Voss, B.2
Kumar, D.3
Hamm, H.E.4
Harth, E.5
-
32
-
-
0141954275
-
Cellular uptake of aminoglycosides, guanidinoglycosides, and poly-arginine
-
DOI 10.1021/ja0360135
-
Luedtke, N. W.; Carmichael, P.; Tor, Y. Cellular uptake of aminoglycosides, guanidinoglycosides, and poly-arginine J. Am. Chem. Soc. 2003, 125, 12374-12375 (Pubitemid 37254733)
-
(2003)
Journal of the American Chemical Society
, vol.125
, Issue.41
, pp. 12374-12375
-
-
Luedtke, N.W.1
Carmichael, P.2
Tor, Y.3
-
33
-
-
78049249549
-
Cooperative, heparin sulfate-dependent cellular uptake of dimeric guanidinoglycosides
-
Dix, A. V.; Fischer, L.; Sarrazin, S.; Redgate, C. P.; Esko, J. D.; Tor, Y. Cooperative, heparin sulfate-dependent cellular uptake of dimeric guanidinoglycosides ChemBioChem 2010, 11, 2302-2310
-
(2010)
ChemBioChem
, vol.11
, pp. 2302-2310
-
-
Dix, A.V.1
Fischer, L.2
Sarrazin, S.3
Redgate, C.P.4
Esko, J.D.5
Tor, Y.6
-
34
-
-
0038615916
-
Novel binding and efficient cellular uptake of guanidine-based peptide nucleic acids (GPNA)
-
DOI 10.1021/ja029665m
-
Zhou, P.; Wang, M.; Du, L.; Fisher, G. W.; Waggoner, A.; Ly, D. H. Novel binding and efficient cellular uptake of guanidine-based peptide nucleic acids (GPNA) J. Am. Chem. Soc. 2003, 125, 6878-6879 (Pubitemid 36682781)
-
(2003)
Journal of the American Chemical Society
, vol.125
, Issue.23
, pp. 6878-6879
-
-
Zhou, P.1
Wang, M.2
Du, L.3
Fisher, G.W.4
Waggoner, A.5
Ly, D.H.6
-
35
-
-
27444444758
-
Nucleic acid with guanidinium modification exhibits efficient cellular uptake
-
DOI 10.1002/anie.200500904
-
Ohmichi, T.; Kuwahara, M.; Sasaki, N.; Hasegawa, M.; Nishikata, T.; Sawai, H.; Sugimoto, N. Nucleic acid with guanidinium modification exhibits efficient cellular uptake Angew. Chem., Int. Ed. 2005, 44, 6682-6685 (Pubitemid 41532210)
-
(2005)
Angewandte Chemie - International Edition
, vol.44
, Issue.41
, pp. 6682-6685
-
-
Ohmichi, T.1
Kuwahara, M.2
Sasaki, N.3
Hasegawa, M.4
Nishikata, T.5
Sawai, H.6
Sugimoto, N.7
-
36
-
-
33645775235
-
Impact of the guanidinium group on hybridization and cellular uptake of cationic oligonucleotides
-
Deglane, G.; Abes, S.; Michel, T.; Prevot, P.; Vives, E.; Debart, F.; Barvik, I.; Lebleu, B.; Vasseur, J. J. Impact of the guanidinium group on hybridization and cellular uptake of cationic oligonucleotides ChemBioChem 2006, 7, 684-692
-
(2006)
ChemBioChem
, vol.7
, pp. 684-692
-
-
Deglane, G.1
Abes, S.2
Michel, T.3
Prevot, P.4
Vives, E.5
Debart, F.6
Barvik, I.7
Lebleu, B.8
Vasseur, J.J.9
-
37
-
-
0028059256
-
Design and synthesis of deoxynucleic guanidine: A polycation analogue of DNA
-
DOI 10.1073/pnas.91.17.7864
-
Dempcy, O. R.; Almarsson, O.; Bruice, T. C. Design and synthesis of deoxynucleic guanidine: a polycation analogue of DNA Proc. Natl. Acad. Sci. U.S.A. 1994, 91, 7864-7868 (Pubitemid 24253845)
-
(1994)
Proceedings of the National Academy of Sciences of the United States of America
, vol.91
, Issue.17
, pp. 7864-7868
-
-
Dempcy, R.O.1
Almarsson, O.2
Bruice, T.C.3
-
38
-
-
0042383244
-
Gene transfer via reversible plasmid condensation with cysteine-flanked, internally spaced arginine-rich peptides
-
DOI 10.1089/104303403767740768
-
Siprashvili, Z.; Scholl, F. A.; Oliver, S. F.; Adams, A.; Contag, C. H.; Wender, P. A.; Khavari, P. A. Gene transfer via reversible plasmid condensation with cysteine-flanked, internally spaced, arginine-rich peptides Hum. Gene Ther. 2003, 14, 1225-1233 (Pubitemid 37034572)
-
(2003)
Human Gene Therapy
, vol.14
, Issue.13
, pp. 1225-1233
-
-
Siprashvili, Z.1
Scholl, F.A.2
Oliver, S.F.3
Adams, A.4
Contag, C.H.5
Wender, P.A.6
Khavari, P.A.7
-
39
-
-
33746863376
-
Cholesteryl Oligoarginine Delivering Vascular Endothelial Growth Factor siRNA Effectively Inhibits Tumor Growth in Colon Adenocarcinoma
-
DOI 10.1016/j.ymthe.2006.03.022, PII S1525001606001420
-
Kim, W. J.; Christensen, L. V.; Jo, S.; Yockman, J. W.; Jeong, J. H.; Kim, Y.-H.; Kim, S. W. Cholesteryl oligoarginine delivering vascular endothelial growth factor siRNA effectively inhibits tumor growth in colon adenocarcinoma Mol. Ther. 2006, 14, 343-350 (Pubitemid 44184964)
-
(2006)
Molecular Therapy
, vol.14
, Issue.3
, pp. 343-350
-
-
Kim, W.J.1
Christensen, L.V.2
Jo, S.3
Yockman, J.W.4
Jeong, J.H.5
Kim, Y.-H.6
Kim, S.W.7
-
40
-
-
34447114618
-
Transvascular delivery of small interfering RNA to the central nervous system
-
DOI 10.1038/nature05901, PII NATURE05901
-
Kumar, P.; Wu, H.; McBride, J. L.; Jung, K.-E.; Kim, M. H.; Davidson, B. L.; Lee, S. K.; Shankar, P.; Manjunath, N. Transvascular delivery of small interfering RNA to the central nervous system Nature 2007, 448, 39-43 (Pubitemid 47037001)
-
(2007)
Nature
, vol.448
, Issue.7149
, pp. 39-43
-
-
Kumar, P.1
Wu, H.2
McBride, J.L.3
Jung, K.-E.4
Hee Kim, M.5
Davidson, B.L.6
Kyung Lee, S.7
Shankar, P.8
Manjunath, N.9
-
41
-
-
84865173768
-
Designed guanidinium-rich amphipathic oligocarbonate molecular transporters complex, deliver and release siRNA in cells
-
Geihe, E. I.; Cooley, C. B.; Simon, J. R.; Kiesewetter, M. K.; Edward, J. A.; Hickerson, R. P.; Kaspar, R. L.; Hedrick, J. L.; Waymouth, R. M.; Wender, P. A. Designed guanidinium-rich amphipathic oligocarbonate molecular transporters complex, deliver and release siRNA in cells Proc. Natl. Acad. Sci. U.S.A. 2012, 109, 13171-13176
-
(2012)
Proc. Natl. Acad. Sci. U.S.A.
, vol.109
, pp. 13171-13176
-
-
Geihe, E.I.1
Cooley, C.B.2
Simon, J.R.3
Kiesewetter, M.K.4
Edward, J.A.5
Hickerson, R.P.6
Kaspar, R.L.7
Hedrick, J.L.8
Waymouth, R.M.9
Wender, P.A.10
-
42
-
-
47749133787
-
Design and synthesis of dendritic molecular transporter that achieves efficient in vivo delivery of morpholino antisense oligo
-
DOI 10.1021/bc8001437
-
Li, Y.-F.; Morcos, P. A. Design and synthesis of dendritic molecular transporter that achieves efficient in vivo delivery of morpholino antisense oligo Bioconjugate Chem. 2008, 19, 1464-1470 (Pubitemid 352032347)
-
(2008)
Bioconjugate Chemistry
, vol.19
, Issue.7
, pp. 1464-1470
-
-
Li, Y.-F.1
Morcos, P.A.2
-
43
-
-
33646261626
-
Permeation peptide conjugates for in vivo molecular imaging applications
-
Bullok, K. E.; Gammon, S. T.; Violini, S.; Prantner, A. M.; Villalobos, V. M.; Sharma, V.; Piwnica-Worms, D. Permeation peptide conjugates for in vivo molecular imaging applications Mol. Imaging 2006, 5, 1-15
-
(2006)
Mol. Imaging
, vol.5
, pp. 1-15
-
-
Bullok, K.E.1
Gammon, S.T.2
Violini, S.3
Prantner, A.M.4
Villalobos, V.M.5
Sharma, V.6
Piwnica-Worms, D.7
-
44
-
-
47749083959
-
Single-molecule motions of oligoarginine transporter conjugates on the plasma membrane of Chinese Hamster ovary cells
-
DOI 10.1021/ja710798b
-
Lee, H.-L.; Dubikovskaya, E. A.; Hwang, H.; Semyonov, A. N.; Wang, H.; Jones, L. R.; Twieg, R. J.; Moerner, W. E.; Wender, P.A. Single-molecule motions of oligoarginine transporter conjugates on the plasma membrane of Chinese hamster ovary cells J. Am. Chem. Soc. 2008, 130, 9364-9370 (Pubitemid 352031145)
-
(2008)
Journal of the American Chemical Society
, vol.130
, Issue.29
, pp. 9364-9370
-
-
Lee, H.-L.1
Dubikovskaya, E.A.2
Hwang, H.3
Semyonov, A.N.4
Wang, H.5
Jones, L.R.6
Twieg, R.J.7
Moerner, W.E.8
Wender, P.A.9
-
45
-
-
34547514819
-
Real-time analysis of uptake and bioactivatable cleavage of luciferin-transporter conjugates in transgenic reporter mice
-
DOI 10.1073/pnas.0703919104
-
Wender, P. A.; Goun, E. A.; Jones, L. R.; Pillow, T. H.; Rothbard, J. B.; Shinde, R.; Contag, C. H. Real-time analysis of uptake and bioactivatable cleavage of luciferin-transporter conjugates in transgenic reporter mice Proc. Natl. Acad. Sci. U.S.A. 2007, 104, 10340-10345 (Pubitemid 47185667)
-
(2007)
Proceedings of the National Academy of Sciences of the United States of America
, vol.104
, Issue.25
, pp. 10340-10345
-
-
Wender, P.A.1
Goun, E.A.2
Jones, L.R.3
Pillow, T.H.4
Rothbard, J.B.5
Shinde, R.6
Contag, C.H.7
-
46
-
-
50449092432
-
Overcoming multidrug resistance of small-molecule therapeutics through conjugation with releasable octaarginine transporters
-
Dubikovskaya, E. A.; Thorne, S. H.; Pillow, T. H.; Contag, C. H.; Wender, P. A. Overcoming multidrug resistance of small-molecule therapeutics through conjugation with releasable octaarginine transporters Proc. Natl. Acad. Sci. U.S.A. 2008, 105, 12128-12133
-
(2008)
Proc. Natl. Acad. Sci. U.S.A.
, vol.105
, pp. 12128-12133
-
-
Dubikovskaya, E.A.1
Thorne, S.H.2
Pillow, T.H.3
Contag, C.H.4
Wender, P.A.5
-
47
-
-
11144229887
-
Tumor imaging by means of proteolytic activation of cell-penetrating peptides
-
DOI 10.1073/pnas.0408191101
-
Jiang, T.; Olson, E. S.; Nguyen, Q. T.; Roy, M.; Jennings, P. A.; Tsien, R. Y. Tumor imaging by means of proteolytic activation of cell-penetrating peptides Proc. Natl. Acad. Sci. U.S.A. 2004, 101, 17867-17872 (Pubitemid 40051978)
-
(2004)
Proceedings of the National Academy of Sciences of the United States of America
, vol.101
, Issue.51
, pp. 17867-17872
-
-
Jiang, T.1
Olson, E.S.2
Nguyen, Q.T.3
Roy, M.4
Jennings, P.A.5
Tsien, R.Y.6
-
48
-
-
33646948225
-
Intracellular cargo delivery by an octaarginine transporter adapted to target prostate cancer cells through cell surface protease activation
-
DOI 10.1021/bc0503216
-
Goun, E. A.; Shinde, R.; Dehnert, K. W.; Adams-Bond, A.; Wender, P. A.; Contag, C. H.; Franc, B. A. Intracellular cargo delivery by an octaarginine transporter adapted to target prostate cancer cells through cell surface protease activation Bioconjugate Chem. 2006, 17, 787-796 (Pubitemid 43794390)
-
(2006)
Bioconjugate Chemistry
, vol.17
, Issue.3
, pp. 787-796
-
-
Goun, E.A.1
Shinde, R.2
Dehnert, K.W.3
Adams-Bond, A.4
Wender, P.A.5
Contag, C.H.6
Franc, B.L.7
-
49
-
-
77749254873
-
Surgery with molecular fluorescence imaging using activatable cell-penetrating peptides decreases residual cancer and improves survival
-
Nguyen, Q. T.; Olson, E. S.; Aguilera, T. A.; Jiang, T.; Scadeng, M.; Ellies, L. G.; Tsien, R. Y. Surgery with molecular fluorescence imaging using activatable cell-penetrating peptides decreases residual cancer and improves survival Proc. Natl. Acad. Sci. U.S.A. 2010, 107, 4317-4322
-
(2010)
Proc. Natl. Acad. Sci. U.S.A.
, vol.107
, pp. 4317-4322
-
-
Nguyen, Q.T.1
Olson, E.S.2
Aguilera, T.A.3
Jiang, T.4
Scadeng, M.5
Ellies, L.G.6
Tsien, R.Y.7
-
50
-
-
0032927941
-
Cancer multidrug resistance
-
DOI 10.1038/5289
-
Persidis, A. Cancer multidrug resistance Nat. Biotechnol. 1999, 17, 94-95 (Pubitemid 29037219)
-
(1999)
Nature Biotechnology
, vol.17
, Issue.1
, pp. 94-95
-
-
Persidis, A.1
-
51
-
-
84862768802
-
Taxol-oligoarginine conjugates overcome drug resistance in-vitro in human ovarian carcinoma
-
Wender, P. A.; Galliher, W. C.; Bhat, N. M.; Pillow, T. H.; Bieber, M. M.; Teng, N. H. Taxol-oligoarginine conjugates overcome drug resistance in-vitro in human ovarian carcinoma Gynecol. Oncol. 2012, 126, 118-123
-
(2012)
Gynecol. Oncol.
, vol.126
, pp. 118-123
-
-
Wender, P.A.1
Galliher, W.C.2
Bhat, N.M.3
Pillow, T.H.4
Bieber, M.M.5
Teng, N.H.6
-
52
-
-
0035909603
-
An efficient, scalable synthesis of the molecular transporter octaarginine via a segment doubling strategy
-
DOI 10.1021/ol0161108
-
Wender, P. A.; Jessop, T. C.; Pattabiraman, K.; Pelkey, E. T.; VanDeusen, C. L. An efficient, scalable synthesis of the molecular transporter octaarginine via a segment doubling strategy Org. Lett. 2001, 3, 3229-3232 (Pubitemid 33625328)
-
(2001)
Organic Letters
, vol.3
, Issue.21
, pp. 3229-3232
-
-
Wender, P.A.1
Jessop, T.C.2
Pattabiraman, K.3
Pelkey, E.T.4
VanDeusen, C.L.5
-
53
-
-
42649099978
-
A polymeric domain that promotes cellular internalization
-
DOI 10.1021/ja8001716
-
Kolonko, E. M.; Kiessling, L. L. A polymeric domain that promotes cellular internalization J. Am. Chem. Soc. 2008, 130, 5626-5627 (Pubitemid 351600476)
-
(2008)
Journal of the American Chemical Society
, vol.130
, Issue.17
, pp. 5626-5627
-
-
Kolonko, E.M.1
Kiessling, L.L.2
-
54
-
-
57049118019
-
Synthetic mimic of antimicrobial peptide with nonmembrane-disrupting antibacterial properties
-
Gabriel, G. J.; Madkour, A. E.; Dabkowski, J. M.; Nelson, C. F.; Nüsslein, K.; Tew, G. N. Synthetic mimic of antimicrobial peptide with nonmembrane-disrupting antibacterial properties Biomacromolecules 2008, 9, 2980-2983
-
(2008)
Biomacromolecules
, vol.9
, pp. 2980-2983
-
-
Gabriel, G.J.1
Madkour, A.E.2
Dabkowski, J.M.3
Nelson, C.F.4
Nüsslein, K.5
Tew, G.N.6
-
55
-
-
67650292734
-
General synthetic route to cell-permeable block copolymers via ROMP
-
Kolonko, E. M.; Pontrello, J. K.; Mangold, S. L.; Kiessling, L. L. General synthetic route to cell-permeable block copolymers via ROMP J. Am. Chem. Soc. 2009, 131, 7327-7333
-
(2009)
J. Am. Chem. Soc.
, vol.131
, pp. 7327-7333
-
-
Kolonko, E.M.1
Pontrello, J.K.2
Mangold, S.L.3
Kiessling, L.L.4
-
56
-
-
84855990645
-
Protein transduction domain mimics: The role of aromatic functionality
-
Som, A.; Reuter, A.; Tew, G. N. Protein transduction domain mimics: The role of aromatic functionality Angew. Chem., Int. Ed. 2012, 51, 980-983
-
(2012)
Angew. Chem., Int. Ed.
, vol.51
, pp. 980-983
-
-
Som, A.1
Reuter, A.2
Tew, G.N.3
-
57
-
-
84873650354
-
Substrate-initated synthesis of cell-penetrating poly(disulfide)s
-
Bang, E.-K.; Gasparini, G.; Molinard, G.; Roux, A.; Sakai, N.; Matile, S. Substrate-initated synthesis of cell-penetrating poly(disulfide)s J. Am. Chem. Soc. 2013, 135, 2088-2091
-
(2013)
J. Am. Chem. Soc.
, vol.135
, pp. 2088-2091
-
-
Bang, E.-K.1
Gasparini, G.2
Molinard, G.3
Roux, A.4
Sakai, N.5
Matile, S.6
-
58
-
-
70450169425
-
Oligocarbonate molecular transporters: Oligomerization-based syntheses and cell-penetrating studies
-
Cooley, C. B.; Trantow, B. M.; Nederberg, F.; Kiesewetter, M. K.; Hedrick, J. L.; Waymouth, R. M.; Wender, P. A. Oligocarbonate molecular transporters: oligomerization-based syntheses and cell-penetrating studies J. Am. Chem. Soc. 2009, 131, 16401-16403
-
(2009)
J. Am. Chem. Soc.
, vol.131
, pp. 16401-16403
-
-
Cooley, C.B.1
Trantow, B.M.2
Nederberg, F.3
Kiesewetter, M.K.4
Hedrick, J.L.5
Waymouth, R.M.6
Wender, P.A.7
-
59
-
-
84871920964
-
Novel protein transduction domain mimics as nonviral delivery vectors for siRNA targeting NOTCH1 in primary human T cells
-
Tezgel, A.Ö.; Gonzalez-Perez, G.; Telfer, J. C.; Osborne, B. A.; Minter, L. M.; Tew, G. N. Novel protein transduction domain mimics as nonviral delivery vectors for siRNA targeting NOTCH1 in primary human T cells Mol. Ther. 2013, 21, 201-209
-
(2013)
Mol. Ther.
, vol.21
, pp. 201-209
-
-
Tezgel, A.Ö.1
Gonzalez-Perez, G.2
Telfer, J.C.3
Osborne, B.A.4
Minter, L.M.5
Tew, G.N.6
-
60
-
-
41949083981
-
Mitochondria-Penetrating Peptides
-
DOI 10.1016/j.chembiol.2008.03.015, PII S1074552108001269
-
Horton, K. L.; Stewart, K. M.; Fonseca, S. B.; Guo, Q.; Kelley, S. O. Mitochondria-penetrating peptides Chem. Biol. 2008, 15, 375-382 (Pubitemid 351508434)
-
(2008)
Chemistry and Biology
, vol.15
, Issue.4
, pp. 375-382
-
-
Horton, K.L.1
Stewart, K.M.2
Fonseca, S.B.3
Guo, Q.4
Kelley, S.O.5
-
61
-
-
84864402585
-
Arginine topology controls escape of minimally cationic proteins from early endosomes to the cytoplasm
-
Appelbaum, J. S.; LaRochelle, J. R.; Smith, B. A.; Balkin, D. M.; Holub, J. M.; Schepartz, A. Arginine topology controls escape of minimally cationic proteins from early endosomes to the cytoplasm Chem. Biol. 2012, 19, 819-830
-
(2012)
Chem. Biol.
, vol.19
, pp. 819-830
-
-
Appelbaum, J.S.1
Larochelle, J.R.2
Smith, B.A.3
Balkin, D.M.4
Holub, J.M.5
Schepartz, A.6
-
62
-
-
67649607267
-
Fluorescein Redirects a Ruthenium-Octaarginine Conjugate to the Nucleus
-
Puckett, C. A.; Barton, J. K. Fluorescein Redirects a Ruthenium-Octaarginine Conjugate to the Nucleus J. Am. Chem. Soc. 2009, 131, 8738-8739
-
(2009)
J. Am. Chem. Soc.
, vol.131
, pp. 8738-8739
-
-
Puckett, C.A.1
Barton, J.K.2
-
63
-
-
66049135249
-
Generation of Induced Pluripotent Stem Cells Using Recombinant Proteins
-
Zhou, H.; Wu, S.; Joo, J. Y.; Zhu, S.; Han, D. W.; Lin, T.; Trauger, S.; Bien, G.; Yao, S.; Zhu, Y.; Siuzdak, G.; Schöler, H. R.; Duan, L.; Ding, S. Generation of Induced Pluripotent Stem Cells Using Recombinant Proteins Cell Stem Cell 2009, 4, 381-384
-
(2009)
Cell Stem Cell
, vol.4
, pp. 381-384
-
-
Zhou, H.1
Wu, S.2
Joo, J.Y.3
Zhu, S.4
Han, D.W.5
Lin, T.6
Trauger, S.7
Bien, G.8
Yao, S.9
Zhu, Y.10
Siuzdak, G.11
Schöler, H.R.12
Duan, L.13
Ding, S.14
-
64
-
-
66049143859
-
Generation of Human Induced Pluripotent Stem Cells by Direct Delivery of Reprogramming Proteins
-
Kim, D.; Kim, C.-H.; Moon, J.-I.; Chung, Y.-G.; Chang, M.-Y.; Han, B.-S.; Ko, S.; Yang, E.; Cha, K. Y.; Lanza, R.; Kim, K.-S. Generation of Human Induced Pluripotent Stem Cells by Direct Delivery of Reprogramming Proteins Cell Stem Cell 2009, 4, 472-476
-
(2009)
Cell Stem Cell
, vol.4
, pp. 472-476
-
-
Kim, D.1
Kim, C.-H.2
Moon, J.-I.3
Chung, Y.-G.4
Chang, M.-Y.5
Han, B.-S.6
Ko, S.7
Yang, E.8
Cha, K.Y.9
Lanza, R.10
Kim, K.-S.11
-
65
-
-
77956747852
-
Micro-algae come of age as a platform for recombinant protein production
-
Specht, E.; Miyake-Stoner, S.; Mayfield, S. Micro-algae come of age as a platform for recombinant protein production Biotechnol. Lett. 2010, 32, 1373-1383
-
(2010)
Biotechnol. Lett.
, vol.32
, pp. 1373-1383
-
-
Specht, E.1
Miyake-Stoner, S.2
Mayfield, S.3
-
66
-
-
77950534012
-
Genetic Engineering of Algae for Enhanced Biofuel Production
-
Radakovits, R.; Jinkerson, R. E.; Darzins, A.; Posewitz, M. C. Genetic Engineering of Algae for Enhanced Biofuel Production Eukaryotic Cell 2010, 9, 486-501
-
(2010)
Eukaryotic Cell
, vol.9
, pp. 486-501
-
-
Radakovits, R.1
Jinkerson, R.E.2
Darzins, A.3
Posewitz, M.C.4
|