메뉴 건너뛰기




Volumn 8, Issue 11, 2013, Pages

Tumor cell death mediated by peptides that recognize branched intermediates of DNA replication and repair

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENTS; CELL CYCLE; CELL DEATH; DNA DAMAGE; DNA REPAIR; DNA REPLICATION; DNA, CRUCIFORM; DNA, NEOPLASM; DOXORUBICIN; ETOPOSIDE; HELA CELLS; HUMANS; PEPTIDES;

EID: 84893685116     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0078751     Document Type: Article
Times cited : (11)

References (66)
  • 2
    • 70049100788 scopus 로고    scopus 로고
    • International guidelines for management of metastatic breast cancer: Combination vs sequential single-agent chemotherapy
    • Cardoso F, Bedard PL, Winer EP, Pagani O, Senkus-Konefka E, et al. (2009) International guidelines for management of metastatic breast cancer: combination vs sequential single-agent chemotherapy. J Natl Cancer Inst 101: 1174-1181.
    • (2009) J Natl Cancer Inst , vol.101 , pp. 1174-1181
    • Cardoso, F.1    Bedard, P.L.2    Winer, E.P.3    Pagani, O.4    Senkus-Konefka, E.5
  • 3
    • 59749091477 scopus 로고    scopus 로고
    • Chemotherapy, bevacizumab, and cetuximab in metastatic colorectal cancer
    • Tol J, Koopman M, Cats A, Rodenburg CJ, Creemers GJ, et al. (2009) Chemotherapy, bevacizumab, and cetuximab in metastatic colorectal cancer. N Engl J Med 360: 563-572.
    • (2009) N Engl J Med , vol.360 , pp. 563-572
    • Tol, J.1    Koopman, M.2    Cats, A.3    Rodenburg, C.J.4    Creemers, G.J.5
  • 4
    • 77953645531 scopus 로고    scopus 로고
    • Optimal delivery of cytotoxic chemotherapy for colon cancer
    • Raftery L, Goldberg RM (2010) Optimal delivery of cytotoxic chemotherapy for colon cancer. Cancer J 16: 214-219.
    • (2010) Cancer J , vol.16 , pp. 214-219
    • Raftery, L.1    Goldberg, R.M.2
  • 7
    • 77955278619 scopus 로고    scopus 로고
    • Targeting homologous recombination repair defects in cancer
    • Evers B, Helleday T, Jonkers J (2010) Targeting homologous recombination repair defects in cancer. Trends Pharmacol Sci 31: 372-380.
    • (2010) Trends Pharmacol Sci , vol.31 , pp. 372-380
    • Evers, B.1    Helleday, T.2    Jonkers, J.3
  • 8
    • 84870218588 scopus 로고    scopus 로고
    • DNA repair dysregulation from cancer driver to therapeutic target
    • Curtin NJ (2012) DNA repair dysregulation from cancer driver to therapeutic target. Nat Rev Cancer 12: 801-817.
    • (2012) Nat Rev Cancer , vol.12 , pp. 801-817
    • Curtin, N.J.1
  • 9
    • 0034951142 scopus 로고    scopus 로고
    • Double-strand-break-induced homologous recombination in mammalian cells
    • DOI 10.1042/0300-5127:0290196
    • Johnson RD, Jasin M (2001) Double-strand-break-induced homologous recombination in mammalian cells. Biochem Soc Trans 29: 196-201. (Pubitemid 32587504)
    • (2001) Biochemical Society Transactions , vol.29 , Issue.2 , pp. 196-201
    • Johnson, R.D.1    Jasin, M.2
  • 10
    • 33749037701 scopus 로고    scopus 로고
    • Mechanism of homologous recombination: Mediators and helicases take on regulatory functions
    • DOI 10.1038/nrm2008, PII NRM2008
    • Sung P, Klein H (2006) Mechanism of homologous recombination: mediators and helicases take on regulatory functions. Nat Rev Mol Cell Biol 7: 739-750. (Pubitemid 44450458)
    • (2006) Nature Reviews Molecular Cell Biology , vol.7 , Issue.10 , pp. 739-750
    • Sung, P.1    Klein, H.2
  • 11
    • 33747889722 scopus 로고    scopus 로고
    • Role of non-homologous end joining (NHEJ) in maintaining genomic integrity
    • DOI 10.1016/j.dnarep.2006.05.026, PII S1568786406001650, Mechanisms of Chromosomal Translocations
    • Burma S, Chen BP, Chen DJ (2006) Role of non-homologous end joining (NHEJ) in maintaining genomic integrity. DNA Repair (Amst) 5: 1042-1048. (Pubitemid 44291616)
    • (2006) DNA Repair , vol.5 , Issue.9-10 , pp. 1042-1048
    • Burma, S.1    Chen, B.P.C.2    Chen, D.J.3
  • 12
    • 38049115657 scopus 로고    scopus 로고
    • The mechanism of human nonhomologous DNA end joining
    • Lieber MR (2008) The mechanism of human nonhomologous DNA end joining. J Biol Chem 283: 1-5.
    • (2008) J Biol Chem , vol.283 , pp. 1-5
    • Lieber, M.R.1
  • 13
    • 46249131123 scopus 로고    scopus 로고
    • Alternative-NHEJ is a mechanistically distinct pathway of mammalian chromosome break repair
    • Bennardo N, Cheng A, Huang N, Stark JM (2008) Alternative-NHEJ is a mechanistically distinct pathway of mammalian chromosome break repair. PLoS Genet 4: e1000110.
    • (2008) PLoS Genet , vol.4
    • Bennardo, N.1    Cheng, A.2    Huang, N.3    Stark, J.M.4
  • 14
    • 11244269445 scopus 로고    scopus 로고
    • The CDK regulates repair of double-strand breaks by homologous recombination during the cell cycle
    • DOI 10.1038/sj.emboj.7600469
    • Aylon Y, Liefshitz B, Kupiec M (2004) The CDK regulates repair of double-strand breaks by homologous recombination during the cell cycle. EMBO J 23: 4868-4875. (Pubitemid 40069716)
    • (2004) EMBO Journal , vol.23 , Issue.24 , pp. 4868-4875
    • Aylon, Y.1    Liefshitz, B.2    Kupiec, M.3
  • 15
    • 39549114009 scopus 로고    scopus 로고
    • Differential Regulation of the Cellular Response to DNA Double-Strand Breaks in G1
    • DOI 10.1016/j.molcel.2008.01.016, PII S1097276508001548
    • Barlow JH, Lisby M, Rothstein R (2008) Differential regulation of the cellular response to DNA double-strand breaks in G1. Mol Cell 30: 73-85. (Pubitemid 351470149)
    • (2008) Molecular Cell , vol.30 , Issue.1 , pp. 73-85
    • Barlow, J.H.1    Lisby, M.2    Rothstein, R.3
  • 17
  • 18
    • 0034705344 scopus 로고    scopus 로고
    • Dissection of bacteriophage lambda site-specific recombination using synthetic peptide combinatorial libraries
    • Cassell G, Klemm M, Pinilla C, Segall A (2000) Dissection of bacteriophage lambda site-specific recombination using synthetic peptide combinatorial libraries. J Mol Biol 299: 1193-1202.
    • (2000) J Mol Biol , vol.299 , pp. 1193-1202
    • Cassell, G.1    Klemm, M.2    Pinilla, C.3    Segall, A.4
  • 19
    • 0942276382 scopus 로고    scopus 로고
    • Reversible Inhibitors of lambda Integrase-mediated Recombination Efficiently Trap Holliday Junction Intermediates and Form the Basis of a Novel Assay for Junction Resolution
    • DOI 10.1074/jbc.M309361200
    • Boldt JL, Pinilla C, Segall AM (2004) Reversible inhibitors of lambda integrase-mediated recombination efficiently trap Holliday junction intermediates and form the basis of a novel assay for junction resolution. J Biol Chem 279: 3472-3483. (Pubitemid 38140586)
    • (2004) Journal of Biological Chemistry , vol.279 , Issue.5 , pp. 3472-3483
    • Boldt, J.L.1    Pinilla, C.2    Segall, A.M.3
  • 21
    • 77955415860 scopus 로고    scopus 로고
    • Small molecule functional analogs of peptides that inhibit lambda site-specific recombination and bind Holliday junctions
    • Ranjit DK, Rideout MC, Nefzi A, Ostresh JM, Pinilla C, et al. (2010) Small molecule functional analogs of peptides that inhibit lambda site-specific recombination and bind Holliday junctions. Bioorg Med Chem Lett 20: 4531-4534.
    • (2010) Bioorg Med Chem Lett , vol.20 , pp. 4531-4534
    • Ranjit, D.K.1    Rideout, M.C.2    Nefzi, A.3    Ostresh, J.M.4    Pinilla, C.5
  • 22
    • 52649093934 scopus 로고    scopus 로고
    • Interactions between branched DNAs and peptide inhibitors of DNA repair
    • Kepple KV, Patel N, Salamon P, Segall AM (2008) Interactions between branched DNAs and peptide inhibitors of DNA repair. Nucleic Acids Res 36: 5319-5334.
    • (2008) Nucleic Acids Res , vol.36 , pp. 5319-5334
    • Kepple, K.V.1    Patel, N.2    Salamon, P.3    Segall, A.M.4
  • 23
    • 84855223328 scopus 로고    scopus 로고
    • Potent antimicrobial small molecules screened as inhibitors of tyrosine recombinases and Holliday junction-resolving enzymes
    • Rideout MC, Boldt JL, Vahi-Ferguson G, Salamon P, Nefzi A, et al. (2011) Potent antimicrobial small molecules screened as inhibitors of tyrosine recombinases and Holliday junction-resolving enzymes. Mol Divers 15: 989-1005.
    • (2011) Mol Divers , vol.15 , pp. 989-1005
    • Rideout, M.C.1    Boldt, J.L.2    Vahi-Ferguson, G.3    Salamon, P.4    Nefzi, A.5
  • 24
    • 64049098351 scopus 로고    scopus 로고
    • Peptide wrwycr inhibits the excision of several prophages and traps holliday junctions inside bacteria
    • Gunderson CW, Boldt JL, Authement RN, Segall AM (2009) Peptide wrwycr inhibits the excision of several prophages and traps holliday junctions inside bacteria. J Bacteriol 191: 2169-2176.
    • (2009) J Bacteriol , vol.191 , pp. 2169-2176
    • Gunderson, C.W.1    Boldt, J.L.2    Authement, R.N.3    Segall, A.M.4
  • 25
    • 33645051465 scopus 로고    scopus 로고
    • DNA repair, a novel antibacterial target: Holliday junction-trapping peptides induce DNA damage and chromosome segregation defects
    • Gunderson CW, Segall AM (2006) DNA repair, a novel antibacterial target: Holliday junction-trapping peptides induce DNA damage and chromosome segregation defects. Mol Microbiol 59: 1129-1148.
    • (2006) Mol Microbiol , vol.59 , pp. 1129-1148
    • Gunderson, C.W.1    Segall, A.M.2
  • 26
    • 35748962638 scopus 로고    scopus 로고
    • The Bacteroides NBU1 integrase performs a homology-independent strand exchange to form a holliday junction intermediate
    • DOI 10.1074/jbc.M705370200
    • Rajeev L, Segall A, Gardner J (2007) The bacteroides NBU1 integrase performs a homology-independent strand exchange to form a holliday junction intermediate. J Biol Chem 282: 31228-31237. (Pubitemid 350044837)
    • (2007) Journal of Biological Chemistry , vol.282 , Issue.43 , pp. 31228-31237
    • Rajeev, L.1    Segall, A.2    Gardner, J.3
  • 27
    • 84873744498 scopus 로고    scopus 로고
    • wrwyrggrywrw is a single-chain functional analog of the Holliday junction-binding homodimer, (wrwycr)2
    • Rideout MC, Naili I, Boldt JL, Flores-Fujimoto A, Patra S, et al. (2013) wrwyrggrywrw is a single-chain functional analog of the Holliday junction-binding homodimer, (wrwycr)2. Peptides 40: 112-122.
    • (2013) Peptides , vol.40 , pp. 112-122
    • Rideout, M.C.1    Naili, I.2    Boldt, J.L.3    Flores-Fujimoto, A.4    Patra, S.5
  • 28
    • 0026076091 scopus 로고
    • Establishment and characterization of a new human prostatic carcinoma cell line (DuPro-1)
    • Gingrich JR, Tucker JA, Walther PJ, Day JW, Poulton SH, et al. (1991) Establishment and characterization of a new human prostatic carcinoma cell line (DuPro-1). J Urol 146: 915-919.
    • (1991) J Urol , vol.146 , pp. 915-919
    • Gingrich, J.R.1    Tucker, J.A.2    Walther, P.J.3    Day, J.W.4    Poulton, S.H.5
  • 30
    • 77951224521 scopus 로고    scopus 로고
    • An antimicrobial peptide that targets DNA repair intermediates in vitro inhibits Salmonella growth within murine macrophages
    • Su LY, Willner DL, Segall AM (2010) An antimicrobial peptide that targets DNA repair intermediates in vitro inhibits Salmonella growth within murine macrophages. Antimicrob Agents Chemother 54: 1888-1899.
    • (2010) Antimicrob Agents Chemother , vol.54 , pp. 1888-1899
    • Su, L.Y.1    Willner, D.L.2    Segall, A.M.3
  • 31
    • 0030960014 scopus 로고    scopus 로고
    • Intracellular volume and apparent diffusion constants of perfused cancer cell cultures, as measured by NMR
    • DOI 10.1002/mrm.1910370605
    • Pilatus U, Shim H, Artemov D, Davis D, van Zijl PC, et al. (1997) Intracellular volume and apparent diffusion constants of perfused cancer cell cultures, as measured by NMR. Magn Reson Med 37: 825-832. (Pubitemid 27270758)
    • (1997) Magnetic Resonance in Medicine , vol.37 , Issue.6 , pp. 825-832
    • Pilatus, U.1    Shim, H.2    Artemov, D.3    Davis, D.4    Van Zijl, P.C.M.5    Glickson, J.D.6
  • 32
    • 0018123331 scopus 로고
    • Induction of alkaline phosphatase activity in HeLa cells by choline chloride
    • Wharton W, Goz B (1978) Induction of alkaline phosphatase activity in HeLa cells by choline chloride. Cancer Res 38: 3764-3768. (Pubitemid 9045203)
    • (1978) Cancer Research , vol.38 , Issue.11 I , pp. 3764-3768
    • Wharton, W.1    Goz, B.2
  • 33
    • 0035449355 scopus 로고    scopus 로고
    • Cell cycle checkpoint signaling through the ATM and ATR kinases
    • Abraham RT (2001) Cell cycle checkpoint signaling through the ATM and ATR kinases. Genes Dev 15: 2177-2196.
    • (2001) Genes Dev , vol.15 , pp. 2177-2196
    • Abraham, R.T.1
  • 34
    • 84872871569 scopus 로고    scopus 로고
    • Tanshinone IIA improves endoplasmic reticulum stress-induced insulin resistance through AMP-activated protein kinase
    • Hwang SL, Yang JH, Jeong YT, Kim YD, Li X, et al. (2013) Tanshinone IIA improves endoplasmic reticulum stress-induced insulin resistance through AMP-activated protein kinase. Biochem Biophys Res Commun 430: 1246-1252.
    • (2013) Biochem Biophys Res Commun , vol.430 , pp. 1246-1252
    • Hwang, S.L.1    Yang, J.H.2    Jeong, Y.T.3    Kim, Y.D.4    Li, X.5
  • 35
    • 0037459219 scopus 로고    scopus 로고
    • Mechanism of inhibition of site-specific recombination by the Holliday junction-trapping peptide WKHYNY: Insights into phage lambda integrase-mediated strand exchange
    • DOI 10.1016/S0022-2836(03)00058-5
    • Cassell GD, Segall AM (2003) Mechanism of inhibition of site-specific recombination by the Holliday junction-trapping peptide WKHYNY: insights into phage lambda integrase-mediated strand exchange. J Mol Biol 327: 413-429. (Pubitemid 36298711)
    • (2003) Journal of Molecular Biology , vol.327 , Issue.2 , pp. 413-429
    • Cassell, G.D.1    Segall, A.M.2
  • 36
    • 0034705325 scopus 로고    scopus 로고
    • Peptide inhibitors of DNA cleavage by tyrosine recombinases and topoisomerases
    • Klemm M, Cheng C, Cassell G, Shuman S, Segall AM (2000) Peptide inhibitors of DNA cleavage by tyrosine recombinases and topoisomerases. J Mol Biol 299: 1203-1216.
    • (2000) J Mol Biol , vol.299 , pp. 1203-1216
    • Klemm, M.1    Cheng, C.2    Cassell, G.3    Shuman, S.4    Segall, A.M.5
  • 37
    • 84873744498 scopus 로고    scopus 로고
    • wrwyrggrywrw is a single-chain functional analog of the Holliday junction-binding homodimer, (wrwycr)(2)
    • Rideout MC, Naili I, Boldt JL, Flores-Fujimoto A, Patra S, et al. (2013) wrwyrggrywrw is a single-chain functional analog of the Holliday junction-binding homodimer, (wrwycr)(2). Peptides.
    • (2013) Peptides
    • Rideout, M.C.1    Naili, I.2    Boldt, J.L.3    Flores-Fujimoto, A.4    Patra, S.5
  • 39
    • 0030879848 scopus 로고    scopus 로고
    • Caspase inhibition selectively reduces the apoptotic component of oxygen-glucose deprivation-induced cortical neuronal cell death
    • DOI 10.1006/mcne.1997.0618
    • Gottron FJ, Ying HS, Choi DW (1997) Caspase inhibition selectively reduces the apoptotic component of oxygen-glucose deprivation-induced cortical neuronal cell death. Mol Cell Neurosci 9: 159-169. (Pubitemid 27323429)
    • (1997) Molecular and Cellular Neurosciences , vol.9 , Issue.3 , pp. 159-169
    • Gottron, F.J.1    Ying, H.S.2    Choi, D.W.3
  • 40
    • 0033781027 scopus 로고    scopus 로고
    • The coordinate release of cytochrome c during apoptosis is rapid, complete and kinetically invariant
    • Goldstein JC, Waterhouse NJ, Juin P, Evan GI, Green DR (2000) The coordinate release of cytochrome c during apoptosis is rapid, complete and kinetically invariant. Nat Cell Biol 2: 156-162.
    • (2000) Nat Cell Biol , vol.2 , pp. 156-162
    • Goldstein, J.C.1    Waterhouse, N.J.2    Juin, P.3    Evan, G.I.4    Green, D.R.5
  • 42
    • 26944433834 scopus 로고    scopus 로고
    • Caspase-independent cytochrome c release is a sensitive measure of low-level apoptosis in cell culture models
    • DOI 10.1111/j.1474-9726.2005.00163.x
    • Goldstein JC, Rodier F, Garbe JC, Stampfer MR, Campisi J (2005) Caspase-independent cytochrome c release is a sensitive measure of low-level apoptosis in cell culture models. Aging Cell 4: 217-222. (Pubitemid 41602743)
    • (2005) Aging Cell , vol.4 , Issue.4 , pp. 217-222
    • Goldstein, J.C.1    Rodier, F.2    Garbe, J.C.3    Stampfer, M.R.4    Campisi, J.5
  • 43
    • 0028670473 scopus 로고
    • Physiological cytosolic Ca2+ transients evoke concurrent mitochondrial depolarizations
    • Loew LM, Carrington W, Tuft RA, Fay FS (1994) Physiological cytosolic Ca2+ transients evoke concurrent mitochondrial depolarizations. Proc Natl Acad Sci U S A 91: 12579-12583.
    • (1994) Proc Natl Acad Sci U S a , vol.91 , pp. 12579-12583
    • Loew, L.M.1    Carrington, W.2    Tuft, R.A.3    Fay, F.S.4
  • 45
    • 77956208698 scopus 로고    scopus 로고
    • In vivo formation of gamma-H2AX and 53BP1 DNA repair foci in blood cells after radioiodine therapy of differentiated thyroid cancer
    • Lassmann M, Hanscheid H, Gassen D, Biko J, Meineke V, et al. (2010) In vivo formation of gamma-H2AX and 53BP1 DNA repair foci in blood cells after radioiodine therapy of differentiated thyroid cancer. J Nucl Med 51: 1318-1325.
    • (2010) J Nucl Med , vol.51 , pp. 1318-1325
    • Lassmann, M.1    Hanscheid, H.2    Gassen, D.3    Biko, J.4    Meineke, V.5
  • 46
    • 50849141104 scopus 로고    scopus 로고
    • Early events in the mammalian response to DNA double-strand breaks
    • Riches LC, Lynch AM, Gooderham NJ (2008) Early events in the mammalian response to DNA double-strand breaks. Mutagenesis 23: 331-339.
    • (2008) Mutagenesis , vol.23 , pp. 331-339
    • Riches, L.C.1    Lynch, A.M.2    Gooderham, N.J.3
  • 47
    • 84860389035 scopus 로고    scopus 로고
    • 53BP1-mediated DNA double strand break repair: Insert bad pun here
    • Noon AT, Goodarzi AA (2011) 53BP1-mediated DNA double strand break repair: insert bad pun here. DNA Repair (Amst) 10: 1071-1076.
    • (2011) DNA Repair (Amst) , vol.10 , pp. 1071-1076
    • Noon, A.T.1    Goodarzi, A.A.2
  • 48
    • 33845666681 scopus 로고    scopus 로고
    • Structural Basis for the Methylation State-Specific Recognition of Histone H4-K20 by 53BP1 and Crb2 in DNA Repair
    • DOI 10.1016/j.cell.2006.10.043, PII S009286740601525X
    • Botuyan MV, Lee J, Ward IM, Kim JE, Thompson JR, et al. (2006) Structural basis for the methylation state-specific recognition of histone H4-K20 by 53BP1 and Crb2 in DNA repair. Cell 127: 1361-1373. (Pubitemid 44960409)
    • (2006) Cell , vol.127 , Issue.7 , pp. 1361-1373
    • Botuyan, M.V.1    Lee, J.2    Ward, I.M.3    Kim, J.-E.4    Thompson, J.R.5    Chen, J.6    Mer, G.7
  • 49
    • 80054051108 scopus 로고    scopus 로고
    • Chk1 is dispensable for G2 arrest in response to sustained DNA damage when the ATM/p53/p21 pathway is functional
    • Lossaint G, Besnard E, Fisher D, Piette J, Dulic V (2011) Chk1 is dispensable for G2 arrest in response to sustained DNA damage when the ATM/p53/p21 pathway is functional. Oncogene 30: 4261-4274.
    • (2011) Oncogene , vol.30 , pp. 4261-4274
    • Lossaint, G.1    Besnard, E.2    Fisher, D.3    Piette, J.4    Dulic, V.5
  • 50
    • 77958498222 scopus 로고    scopus 로고
    • The ATM-Chk2 and ATR-Chk1 pathways in DNA damage signaling and cancer
    • Smith J, Tho LM, Xu N, Gillespie DA (2010) The ATM-Chk2 and ATR-Chk1 pathways in DNA damage signaling and cancer. Adv Cancer Res 108: 73-112.
    • (2010) Adv Cancer Res , vol.108 , pp. 73-112
    • Smith, J.1    Tho, L.M.2    Xu, N.3    Gillespie, D.A.4
  • 51
    • 0034780493 scopus 로고    scopus 로고
    • Periplasmic stress and ECF sigma factors
    • DOI 10.1146/annurev.micro.55.1.591
    • Raivio TL, Silhavy TJ (2001) Periplasmic stress and ECF sigma factors. Annu Rev Microbiol 55: 591-624. (Pubitemid 32978117)
    • (2001) Annual Review of Microbiology , vol.55 , pp. 591-624
    • Raivio, T.L.1    Silhavy, T.J.2
  • 52
    • 19944402536 scopus 로고    scopus 로고
    • Envelope stress responses and Gram-negative bacterial pathogenesis
    • Raivio TL (2005) Envelope stress responses and Gram-negative bacterial pathogenesis. Mol Microbiol 56: 1119-1128.
    • (2005) Mol Microbiol , vol.56 , pp. 1119-1128
    • Raivio, T.L.1
  • 54
    • 84867423414 scopus 로고    scopus 로고
    • Similarities between exogenously- and endogenously-induced envelope stress: The effects of a new antibacterial molecule, TPI1609-10
    • Yitzhaki S, Rostron JE, Xu Y, Rideout MC, Authement RN, et al. (2012) Similarities between exogenously- and endogenously-induced envelope stress: the effects of a new antibacterial molecule, TPI1609-10. PLoS One 7: e44896.
    • (2012) PLoS One , vol.7
    • Yitzhaki, S.1    Rostron, J.E.2    Xu, Y.3    Rideout, M.C.4    Authement, R.N.5
  • 55
    • 84870484663 scopus 로고    scopus 로고
    • Endoplasmic Reticulum Stress in Cardiometabolic Disorders
    • Ozcan L (2012) Endoplasmic Reticulum Stress in Cardiometabolic Disorders. Curr Atheroscler Rep.
    • (2012) Curr Atheroscler Rep.
    • Ozcan, L.1
  • 56
    • 33847349283 scopus 로고    scopus 로고
    • Reactive oxygen species: A breath of life or death?
    • DOI 10.1158/1078-0432.CCR-06-2082
    • Fruehauf JP, Meyskens FL Jr (2007) Reactive oxygen species: a breath of life or death? Clin Cancer Res 13: 789-794. (Pubitemid 46340350)
    • (2007) Clinical Cancer Research , vol.13 , Issue.3 , pp. 789-794
    • Fruehauf, J.P.1    Meyskens Jr., F.L.2
  • 57
    • 9244234509 scopus 로고    scopus 로고
    • Defective DNA strand break repair after DNA damage in prostate cancer cells: Implications for genetic instability and prostate cancer progression
    • DOI 10.1158/0008-5472.CAN-04-1601
    • Fan R, Kumaravel TS, Jalali F, Marrano P, Squire JA, et al. (2004) Defective DNA strand break repair after DNA damage in prostate cancer cells: implications for genetic instability and prostate cancer progression. Cancer Res 64: 8526-8533. (Pubitemid 39552064)
    • (2004) Cancer Research , vol.64 , Issue.23 , pp. 8526-8533
    • Fan, R.1    Kumaravel, T.S.2    Jalali, F.3    Marrano, P.4    Squire, J.A.5    Bristow, R.G.6
  • 58
    • 84875365306 scopus 로고    scopus 로고
    • DNA repair inhibitors: The next major step to improve cancer therapy
    • Barakat K, Gajewski M, Tuszynski JA (2012) DNA repair inhibitors: the next major step to improve cancer therapy. Curr Top Med Chem 12: 1376-1390.
    • (2012) Curr Top Med Chem , vol.12 , pp. 1376-1390
    • Barakat, K.1    Gajewski, M.2    Tuszynski, J.A.3
  • 59
    • 84856288224 scopus 로고    scopus 로고
    • H2AX phosphorylation at the sites of DNA double-strand breaks in cultivated mammalian cells and tissues
    • Firsanov DV, Solovjeva LV, Svetlova MP (2011) H2AX phosphorylation at the sites of DNA double-strand breaks in cultivated mammalian cells and tissues. Clin Epigenetics 2: 283-297.
    • (2011) Clin Epigenetics , vol.2 , pp. 283-297
    • Firsanov, D.V.1    Solovjeva, L.V.2    Svetlova, M.P.3
  • 60
    • 0024209811 scopus 로고
    • Autonomous functional domains of chemically synthesized human immunodeficiency virus tat trans-activator protein
    • DOI 10.1016/0092-8674(88)90262-0
    • Green M, Loewenstein PM (1988) Autonomous functional domains of chemically synthesized human immunodeficiency virus tat trans-activator protein. Cell 55: 1179-1188. (Pubitemid 19020070)
    • (1988) Cell , vol.55 , Issue.6 , pp. 1179-1188
    • Green, M.1    Loewenstein, P.M.2
  • 61
    • 0030904245 scopus 로고    scopus 로고
    • A truncated HIV-1 Tat protein basic domain rapidly translocates through the plasma membrane and accumulates in the cell nucleus
    • DOI 10.1074/jbc.272.25.16010
    • Vives E, Brodin P, Lebleu B (1997) A truncated HIV-1 Tat protein basic domain rapidly translocates through the plasma membrane and accumulates in the cell nucleus. J Biol Chem 272: 16010-16017. (Pubitemid 27265584)
    • (1997) Journal of Biological Chemistry , vol.272 , Issue.25 , pp. 16010-16017
    • Vives, E.1    Brodin, P.2    Lebleu, B.3
  • 62
    • 33747038452 scopus 로고    scopus 로고
    • Cell-penetrating peptides-A brief introduction
    • DOI 10.1016/j.bbamem.2006.02.012, PII S0005273606000642
    • Jarver P, Langel U (2006) Cell-penetrating peptides-a brief introduction. Biochim Biophys Acta 1758: 260-263. (Pubitemid 44262272)
    • (2006) Biochimica et Biophysica Acta - Biomembranes , vol.1758 , Issue.3 , pp. 260-263
    • Jarver, P.1    Langel, U.2
  • 63
    • 0032200757 scopus 로고    scopus 로고
    • Microscopic observations of the different morphological changes caused by anti-bacterial peptides on Klebsiella pneumoniae and HL-60 leukemia cells
    • Chan SC, Yau WL, Wang W, Smith DK, Sheu FS, et al. (1998) Microscopic observations of the different morphological changes caused by anti-bacterial peptides on Klebsiella pneumoniae and HL-60 leukemia cells. J Pept Sci 4: 413-425. (Pubitemid 128548609)
    • (1998) Journal of Peptide Science , vol.4 , Issue.7 , pp. 413-425
    • Chan, S.C.1    Yau, W.L.2    Wang, W.3    Smith, D.K.4    Sheu, F.-S.5    Chen, H.M.6
  • 64
    • 0035811496 scopus 로고    scopus 로고
    • Endonuclease G is an apoptotic DNase when released from mitochondria
    • DOI 10.1038/35083620
    • Li LY, Luo X, Wang X (2001) Endonuclease G is an apoptotic DNase when released from mitochondria. Nature 412: 95-99. (Pubitemid 32851517)
    • (2001) Nature , vol.412 , Issue.6842 , pp. 95-99
    • Li, L.Y.1    Luo, X.2    Wang, X.3
  • 65
    • 78649901091 scopus 로고    scopus 로고
    • Alternative cell death mechanisms in development and beyond
    • Yuan J, Kroemer G (2010) Alternative cell death mechanisms in development and beyond. Genes Dev 24: 2592-2602.
    • (2010) Genes Dev , vol.24 , pp. 2592-2602
    • Yuan, J.1    Kroemer, G.2
  • 66
    • 84864255303 scopus 로고    scopus 로고
    • Docetaxel: A review of its use for the first-line treatment of advanced castration-resistant prostate cancer
    • McKeage K (2012) Docetaxel: a review of its use for the first-line treatment of advanced castration-resistant prostate cancer. Drugs 72: 1559-1577.
    • (2012) Drugs , vol.72 , pp. 1559-1577
    • McKeage, K.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.