Small molecule functional analogs of peptides that inhibit λ site-specific recombination and bind Holliday junctions

Bioorganic and Medicinal Chemistry Letters

Volumn 20, Issue 15, 2010, Pages 4531-4534

  Ranjit, Dev K ^a,c   Rideout, Marc C ^a   Nefzi, Adel ^b   Ostresh, John M ^b   Pinilla, Clemencia ^b   Segall, Anca M ^a  

^a SAN DIEGO STATE UNIVERSITY   (United States)

^b TORREY PINES INSTITUTE FOR MOLECULAR STUDIES   (United States)

^c UNIVERSITY OF NEBRASKA MEDICAL CENTER   (United States)

Author keywords

Integrase; Combinatorial libraries; Holliday junction; RecG helicase; Site specific recombination

Indexed keywords

2 (4 NITRO PHENYL) ETHYL; ANTIBIOTIC AGENT; N METHYL AMINOCYCLIC THIOUREA; N' N DIMETHYL S PROPYLAMINE; PEPTIDE DERIVATIVE; R HYDROXY METHYL; RECG HELICASE; S 3 METHYL 1 METHYL INDOLE; THIOUREA DERIVATIVE; TRYPTOPHYLARGINYLTRYPTOPHYLTYROSYLCYSTEINYLARGININE; UNCLASSIFIED DRUG;

ANTIBACTERIAL ACTIVITY; ARTICLE; BACTERIAL CELL; BACTERIAL OUTER MEMBRANE; BINDING COMPETITION; COMPETITIVE INHIBITION; CONTROLLED STUDY; DNA RECOMBINATION; DRUG DETERMINATION; DRUG PROTEIN BINDING; ENZYME ACTIVE SITE; ESCHERICHIA COLI; HOLLIDAY JUNCTION; IN VITRO STUDY; MEMBRANE PERMEABILITY; MOLECULAR LIBRARY; NONHUMAN; SALMONELLA ENTERICA;

AMINO ACID SEQUENCE; ANTI-BACTERIAL AGENTS; BACTERIAL PROTEINS; BACTERIOPHAGE LAMBDA; COMBINATORIAL CHEMISTRY TECHNIQUES; DNA REPAIR; DNA, CRUCIFORM; INTEGRASES; NITRO COMPOUNDS; PEPTIDES; PROPYLAMINES; RECOMBINATION, GENETIC; SMALL MOLECULE LIBRARIES;

BACTERIA (MICROORGANISMS);

EID: 77955415860     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2010.06.029     Document Type: Article

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