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Volumn 116, Issue 2, 2014, Pages 349-356

Incidence and prognostic value of multiple gene promoter methylations in gliomas

Author keywords

Biomarker; Glioma; Promoter methylation; Serum

Indexed keywords

DEATH ASSOCIATED PROTEIN KINASE; ISOCITRATE DEHYDROGENASE 1; METHYLATED DNA PROTEIN CYSTEINE METHYLTRANSFERASE; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE 1; PROTEIN TYROSINE PHOSPHATASE SHP 1; TISSUE INHIBITOR OF METALLOPROTEINASE 3;

EID: 84893674946     PISSN: 0167594X     EISSN: 15737373     Source Type: Journal    
DOI: 10.1007/s11060-013-1301-5     Document Type: Article
Times cited : (16)

References (50)
  • 1
    • 0037068329 scopus 로고    scopus 로고
    • DNA methylation analysis: A powerful new tool for lung cancer diagnosis
    • 1:CAS:528:DC%2BD38XlslSqt7g%3D 12154407 10.1038/sj.onc.1205605
    • Tsou JA, Hagen JA, Carpenter CL et al (2002) DNA methylation analysis: a powerful new tool for lung cancer diagnosis. Oncogene 21:5450-5461
    • (2002) Oncogene , vol.21 , pp. 5450-5461
    • Tsou, J.A.1    Hagen, J.A.2    Carpenter, C.L.3
  • 2
    • 33847065486 scopus 로고    scopus 로고
    • The epigenomics of cancer
    • 1:CAS:528:DC%2BD2sXis12ju7k%3D 17320506 10.1016/j.cell.2007.01.029
    • Jones PA, Baylin SB (2007) The epigenomics of cancer. Cell 128(4):683-692
    • (2007) Cell , vol.128 , Issue.4 , pp. 683-692
    • Jones, P.A.1    Baylin, S.B.2
  • 3
    • 0034176798 scopus 로고    scopus 로고
    • DNA hypermethylation in tumorigenesis: Epigenetics joins genetics
    • 1:CAS:528:DC%2BD3cXit1Sqsbg%3D 10729832 10.1016/S0168-9525(99)01971-X
    • Baylin SB, Herman JG (2000) DNA hypermethylation in tumorigenesis: epigenetics joins genetics. Trends Genet 16(4):168-174
    • (2000) Trends Genet , vol.16 , Issue.4 , pp. 168-174
    • Baylin, S.B.1    Herman, J.G.2
  • 4
    • 0036274359 scopus 로고    scopus 로고
    • The fundamental role of epigenetic events in cancer
    • 1:CAS:528:DC%2BD38XksFOmsrw%3D 12042769 10.1038/nrg962
    • Jones PA, Baylin SB (2002) The fundamental role of epigenetic events in cancer. Nat Rev Genet 3:415-428
    • (2002) Nat Rev Genet , vol.3 , pp. 415-428
    • Jones, P.A.1    Baylin, S.B.2
  • 5
    • 16544395591 scopus 로고    scopus 로고
    • DNA methylation and cancer
    • 1:CAS:528:DC%2BD2cXhtFWqt7%2FE 15542813 10.1200/JCO.2004.07.151
    • Das PM, Singal R (2004) DNA methylation and cancer. J Clin Oncol 22:4632-4642
    • (2004) J Clin Oncol , vol.22 , pp. 4632-4642
    • Das, P.M.1    Singal, R.2
  • 6
    • 4544250024 scopus 로고    scopus 로고
    • Gene-promoter hypermethylation as a biomarker in lung cancer
    • 1:CAS:528:DC%2BD2cXntFCmsbY%3D 15343277 10.1038/nrc1432
    • Belinsky SA (2004) Gene-promoter hypermethylation as a biomarker in lung cancer. Nat Rev Cancer 4:707-717
    • (2004) Nat Rev Cancer , vol.4 , pp. 707-717
    • Belinsky, S.A.1
  • 7
    • 0035872408 scopus 로고    scopus 로고
    • High frequency of promoter hypermethylation of RASSF1A in nasopharyngeal carcinoma
    • 1:CAS:528:DC%2BD3MXktVWqs7s%3D 11358799
    • Lo KW, Kwong J, Hui AB et al (2001) High frequency of promoter hypermethylation of RASSF1A in nasopharyngeal carcinoma. Cancer Res 61:3877-3881
    • (2001) Cancer Res , vol.61 , pp. 3877-3881
    • Lo, K.W.1    Kwong, J.2    Hui, A.B.3
  • 8
    • 31544444483 scopus 로고    scopus 로고
    • CpG island hypermethylation in progression of esophageal and gastric cancer
    • 1:CAS:528:DC%2BD28XhsFGiurg%3D 16362978 10.1002/cncr.21657
    • Sato F, Meltzer SJ (2006) CpG island hypermethylation in progression of esophageal and gastric cancer. Cancer 106:483-493
    • (2006) Cancer , vol.106 , pp. 483-493
    • Sato, F.1    Meltzer, S.J.2
  • 9
    • 0032587192 scopus 로고    scopus 로고
    • Aberrant methylation of p16INK4a and deletion of p15INK4b are frequent events in human esophageal cancer in Linxian, China
    • 1:CAS:528:DyaK1MXmslClug%3D%3D 9934853 10.1093/carcin/20.1.77
    • Xing EP, Nie Y, Wang LD et al (1999) Aberrant methylation of p16INK4a and deletion of p15INK4b are frequent events in human esophageal cancer in Linxian, China. Carcinogenesis 20:77-84
    • (1999) Carcinogenesis , vol.20 , pp. 77-84
    • Xing, E.P.1    Nie, Y.2    Wang, L.D.3
  • 10
    • 0036799084 scopus 로고    scopus 로고
    • Detection of multiple gene hypermethylation in the development of esophageal squamous cell carcinoma
    • 1:CAS:528:DC%2BD38XnvF2qtr4%3D 12376481 10.1093/carcin/23.10.1713
    • Nie Y, Liao J, Zhao X et al (2002) Detection of multiple gene hypermethylation in the development of esophageal squamous cell carcinoma. Carcinogenesis 23:1713-1720
    • (2002) Carcinogenesis , vol.23 , pp. 1713-1720
    • Nie, Y.1    Liao, J.2    Zhao, X.3
  • 11
    • 1642413542 scopus 로고    scopus 로고
    • Serum DNA as a tool for cancer patient management
    • 1:CAS:528:DC%2BD2cXitFCgsA%3D%3D 14737938
    • Ramirez JL, Taron M, Balana C et al (2003) Serum DNA as a tool for cancer patient management. Rocz Akad Med Bialymst 48:34-41
    • (2003) Rocz Akad Med Bialymst , vol.48 , pp. 34-41
    • Ramirez, J.L.1    Taron, M.2    Balana, C.3
  • 12
    • 33847743057 scopus 로고    scopus 로고
    • Circulating tumour-derived nucleic acids in cancer patients: Potential applications as tumour markers
    • 1:CAS:528:DC%2BD2sXisVGis7w%3D 2360081 17311021 10.1038/sj.bjc.6603625
    • Chan KC, Lo YM (2007) Circulating tumour-derived nucleic acids in cancer patients: potential applications as tumour markers. Br J Cancer 96(5):681-685
    • (2007) Br J Cancer , vol.96 , Issue.5 , pp. 681-685
    • Chan, K.C.1    Lo, Y.M.2
  • 13
    • 0035870248 scopus 로고    scopus 로고
    • A gene hypermethylation profile of human cancer
    • 1:CAS:528:DC%2BD3MXjtFSjt7g%3D 11309270
    • Esteller M, Corn PG, Baylin SB, Herman JG (2001) A gene hypermethylation profile of human cancer. Cancer Res 61:3225-3229
    • (2001) Cancer Res , vol.61 , pp. 3225-3229
    • Esteller, M.1    Corn, P.G.2    Baylin, S.B.3    Herman, J.G.4
  • 14
    • 45449105220 scopus 로고    scopus 로고
    • Microsatellite analysis of allelic imbalance in tumour and blood from patients with prostate cancer
    • 18336598 10.1111/j.1464-410X.2008.07600.x
    • Schwarzenbach H, Chun FK, Muller I et al (2008) Microsatellite analysis of allelic imbalance in tumour and blood from patients with prostate cancer. BJU Int 102(2):253-258
    • (2008) BJU Int , vol.102 , Issue.2 , pp. 253-258
    • Schwarzenbach, H.1    Chun, F.K.2    Muller, I.3
  • 15
    • 28044468634 scopus 로고    scopus 로고
    • Detection and quantification of mutations in the plasma of patients with colorectal tumors
    • 1:CAS:528:DC%2BD2MXht1CgurvI 16258065 10.1073/pnas.0507904102
    • Diehl F, Li M, Dressman D et al (2005) Detection and quantification of mutations in the plasma of patients with colorectal tumors. Proc Natl Acad Sci USA 102(45):16368-16373
    • (2005) Proc Natl Acad Sci USA , vol.102 , Issue.45 , pp. 16368-16373
    • Diehl, F.1    Li, M.2    Dressman, D.3
  • 16
    • 19944433956 scopus 로고    scopus 로고
    • Identification of epigenetic aberrant promoter methylation in serum DNA is useful for early detection of lung cancer
    • 1:CAS:528:DC%2BD2MXht1yntLg%3D 15709192
    • Fujiwara K, Fujimoto N, Tabata M et al (2005) Identification of epigenetic aberrant promoter methylation in serum DNA is useful for early detection of lung cancer. Clin Cancer Res 11(3):1219-1225
    • (2005) Clin Cancer Res , vol.11 , Issue.3 , pp. 1219-1225
    • Fujiwara, K.1    Fujimoto, N.2    Tabata, M.3
  • 17
    • 0028179558 scopus 로고
    • Dangers of using 'Optimal' cutpoints in the valuation of prognostic factors
    • 1:STN:280:DyaK2c3jvVOjtQ%3D%3D 8182763 10.1093/jnci/86.11.829
    • Altman DG, Lausen B, Sauerbrei B et al (1994) Dangers of using 'Optimal' cutpoints in the valuation of prognostic factors. J Natl Cancer Inst 86:829-835
    • (1994) J Natl Cancer Inst , vol.86 , pp. 829-835
    • Altman, D.G.1    Lausen, B.2    Sauerbrei, B.3
  • 18
    • 0020343311 scopus 로고
    • Maximally selected Chi square statistics
    • 10.2307/2529881
    • Miller R, Siegmund D (1982) Maximally selected Chi square statistics. Biometrics 38(4):1011-1016
    • (1982) Biometrics , vol.38 , Issue.4 , pp. 1011-1016
    • Miller, R.1    Siegmund, D.2
  • 19
    • 33847743057 scopus 로고    scopus 로고
    • Circulating tumor-derived nucleic acids in cancer patients: Potential applications as tumour makers
    • 1:CAS:528:DC%2BD2sXisVGis7w%3D 2360081 17311021 10.1038/sj.bjc.6603625
    • Chan KC, Lo YM (2007) Circulating tumor-derived nucleic acids in cancer patients: potential applications as tumour makers. Br J Cancer 96:681-685
    • (2007) Br J Cancer , vol.96 , pp. 681-685
    • Chan, K.C.1    Lo, Y.M.2
  • 20
    • 33646847495 scopus 로고    scopus 로고
    • Cell-free and cell-bound circulating DNA in breast tumours: DNA quantification and analysis of tumor-related gene methylation
    • 1:CAS:528:DC%2BD28XksFKnur8%3D 2361269 16641902 10.1038/sj.bjc.6603117
    • Skvortsova TE, Rykova EY, Tamkovich SN et al (2006) Cell-free and cell-bound circulating DNA in breast tumours: DNA quantification and analysis of tumor-related gene methylation. Br J Cancer 94:1492-1495
    • (2006) Br J Cancer , vol.94 , pp. 1492-1495
    • Skvortsova, T.E.1    Rykova, E.Y.2    Tamkovich, S.N.3
  • 21
    • 75849139815 scopus 로고    scopus 로고
    • Serum DNA can define tumor-specific genetic and epigenetic markers in gliomas of various grades
    • 1:CAS:528:DC%2BC3cXotFKitbs%3D 2940579 20150384 10.1093/neuonc/nop041
    • Lavon I, Refael M, Zelikovitch B et al (2010) Serum DNA can define tumor-specific genetic and epigenetic markers in gliomas of various grades. Neuro-oncology 12:173-180
    • (2010) Neuro-oncology , vol.12 , pp. 173-180
    • Lavon, I.1    Refael, M.2    Zelikovitch, B.3
  • 22
    • 61449150588 scopus 로고    scopus 로고
    • Circulating plasma DNA as diagnostic biomarker in non-cell lung cancer
    • 18804892 10.1016/j.lungcan.2008.07.012
    • Paci M, Bellesia E, Maramotti S et al (2009) Circulating plasma DNA as diagnostic biomarker in non-cell lung cancer. Lung Cancer 64:92-97
    • (2009) Lung Cancer , vol.64 , pp. 92-97
    • Paci, M.1    Bellesia, E.2    Maramotti, S.3
  • 23
    • 77954711621 scopus 로고    scopus 로고
    • Genetic variants in inflammation pathway genes and asthma in glioma susceptibility
    • 1:CAS:528:DC%2BC3cXotVWmsb0%3D 2940617 20406895
    • Amirian E, Liu Y, Michael E (2010) Genetic variants in inflammation pathway genes and asthma in glioma susceptibility. Neuro Oncol 12:444-452
    • (2010) Neuro Oncol , vol.12 , pp. 444-452
    • Amirian, E.1    Liu, Y.2    Michael, E.3
  • 24
    • 65649121938 scopus 로고    scopus 로고
    • Glioblastoma multiforme oncogenomics and signaling pathways
    • Okezie O, Kanu BH (2009) Glioblastoma multiforme oncogenomics and signaling pathways. Clin Med Oncol 3:39-52
    • (2009) Clin Med Oncol , vol.3 , pp. 39-52
    • Okezie, O.1    Kanu, B.H.2
  • 25
    • 33847784252 scopus 로고    scopus 로고
    • Loss of PARP-1 affects gene expression profile in a genome-wide manner in ES cells and liver cells
    • 1810537 17286852 10.1186/1471-2164-8-41
    • Ogino H, Nozaki T, Gunji A et al (2007) Loss of PARP-1 affects gene expression profile in a genome-wide manner in ES cells and liver cells. BMC Genomics 8:41
    • (2007) BMC Genomics , vol.8 , pp. 41
    • Ogino, H.1    Nozaki, T.2    Gunji, A.3
  • 26
    • 70350340573 scopus 로고    scopus 로고
    • Cells deficient in PARP-1 shows an accelerated accumulation of DNA single strand breaks, but not AP sites, over the PARP-1 proficient cells exposed to MMS
    • 10.1016/j.mrfmmm.2009.09.006 1:CAS:528:DC%2BD1MXhtlCmsLvJ 2784157 19778542 10.1016/j.mrfmmm.2009.09.006
    • Pachkowski BF, Tano K, Afonin V et al (2009) Cells deficient in PARP-1 shows an accelerated accumulation of DNA single strand breaks, but not AP sites, over the PARP-1 proficient cells exposed to MMS. Mutat Res 671:93-99. doi: 10.1016/j.mrfmmm.2009.09.006
    • (2009) Mutat Res , vol.671 , pp. 93-99
    • Pachkowski, B.F.1    Tano, K.2    Afonin, V.3
  • 27
    • 33749316516 scopus 로고    scopus 로고
    • PARP-1 inhibitors: Are they the long sought genetically specific drugs for BRCA1/2 associated breast cancers?
    • Joseph A, Soto D, Deng C (2006) PARP-1 inhibitors: are they the long sought genetically specific drugs for BRCA1/2 associated breast cancers? Int J Med Sci 3:117-123
    • (2006) Int J Med Sci , vol.3 , pp. 117-123
    • Joseph, A.1    Soto, D.2    Deng, C.3
  • 28
    • 84863987469 scopus 로고    scopus 로고
    • DNA damage and breast cancer
    • 10.5306/wjco.v2.i9.329
    • Davis JD, Lin SY (2011) DNA damage and breast cancer. World J Clin Oncol 10:329-338
    • (2011) World J Clin Oncol , vol.10 , pp. 329-338
    • Davis, J.D.1    Lin, S.Y.2
  • 29
    • 0037434930 scopus 로고    scopus 로고
    • The function of the protein tyrosine phosphatase SHP-1 in cancer
    • 1:CAS:528:DC%2BD3sXit1Ggtr8%3D 12657462 10.1016/S0378-1119(03)00400-1
    • Wu C, Sun M, Liu L (2003) The function of the protein tyrosine phosphatase SHP-1 in cancer. Gene 306:1-12
    • (2003) Gene , vol.306 , pp. 1-12
    • Wu, C.1    Sun, M.2    Liu, L.3
  • 30
    • 0034790737 scopus 로고    scopus 로고
    • Reduction of hematopoietic cell-specific tyrosine phosphatase SHP-1 gene expression in natural killer cell lymphoma and various types of lymphomas/leukemias: Combination analysis with cDNA expression array and tissue microarray
    • 1:CAS:528:DC%2BD3MXnvVCms7c%3D 11583976 10.1016/S0002-9440(10)62535-7
    • Oka T, Yoshino T, Hayashi K et al (2001) Reduction of hematopoietic cell-specific tyrosine phosphatase SHP-1 gene expression in natural killer cell lymphoma and various types of lymphomas/leukemias: combination analysis with cDNA expression array and tissue microarray. Am J Pathol 159:1495-1505
    • (2001) Am J Pathol , vol.159 , pp. 1495-1505
    • Oka, T.1    Yoshino, T.2    Hayashi, K.3
  • 31
    • 70749090028 scopus 로고    scopus 로고
    • Assessment of DNA methylation for the detection of cervical neoplasia in liquid-based cytology specimens
    • 1:CAS:528:DC%2BD1MXhsFahtr%2FN 19836067 10.1016/j.ygyno.2009.09.032
    • Kim JH, Choi YD, Lee JS et al (2010) Assessment of DNA methylation for the detection of cervical neoplasia in liquid-based cytology specimens. Gynecol Oncol 116:99-104
    • (2010) Gynecol Oncol , vol.116 , pp. 99-104
    • Kim, J.H.1    Choi, Y.D.2    Lee, J.S.3
  • 32
    • 32144453842 scopus 로고    scopus 로고
    • JAK/STAT signal transduction: Regulators and implication in hematological malignancies
    • 1:CAS:528:DC%2BD28XhtlKmt70%3D 16426581 10.1016/j.bcp.2005.12.017
    • Valentino L, Pierre J (2006) JAK/STAT signal transduction: regulators and implication in hematological malignancies. Biochem Pharmacol 71:713-721
    • (2006) Biochem Pharmacol , vol.71 , pp. 713-721
    • Valentino, L.1    Pierre, J.2
  • 33
    • 68649085640 scopus 로고    scopus 로고
    • Methylated DAPK and APC promoter DNA detection in peripheral blood is significantly associated with apparent residual tumor and outcome
    • 1:CAS:528:DC%2BD1MXptFCntL0%3D 19259700 10.1007/s00432-009-0564-x
    • Hoffmann AC, Vallbohmer D, Prenzel K et al (2009) Methylated DAPK and APC promoter DNA detection in peripheral blood is significantly associated with apparent residual tumor and outcome. J Cancer Res Clin Oncol 135:1231-1237
    • (2009) J Cancer Res Clin Oncol , vol.135 , pp. 1231-1237
    • Hoffmann, A.C.1    Vallbohmer, D.2    Prenzel, K.3
  • 34
    • 78650504704 scopus 로고    scopus 로고
    • Promoter methylation of p16, Runx3, DAPK and CHFR genes is frequent in gastric carcinoma
    • 1:CAS:528:DC%2BC3MXntlyhsLk%3D 21302620
    • Hu SL, Kong XY, Cheng ZD et al (2010) Promoter methylation of p16, Runx3, DAPK and CHFR genes is frequent in gastric carcinoma. Tumori 96:726-733
    • (2010) Tumori , vol.96 , pp. 726-733
    • Hu, S.L.1    Kong, X.Y.2    Cheng, Z.D.3
  • 35
    • 41149143617 scopus 로고    scopus 로고
    • Multiple gene methylation of nonsmall cell lung cancers evaluated with 3-dimensional microarray
    • 1:CAS:528:DC%2BD1cXksFKisr8%3D 18286531 10.1002/cncr.23312
    • Wang Y, Zhang D, Zheng W et al (2008) Multiple gene methylation of nonsmall cell lung cancers evaluated with 3-dimensional microarray. Cancer 112:1325-1336
    • (2008) Cancer , vol.112 , pp. 1325-1336
    • Wang, Y.1    Zhang, D.2    Zheng, W.3
  • 36
    • 33644686386 scopus 로고    scopus 로고
    • Hypermethylation of the TPEF/HPP1 gene in primary and metastatic colorectal cancers
    • 1:CAS:528:DC%2BD2MXht1Sitr7M 1501884 16207479 10.1593/neo.05235
    • Ebert MP, Mooney SH, Tonnes-Priddy L et al (2005) Hypermethylation of the TPEF/HPP1 gene in primary and metastatic colorectal cancers. Neoplasia 7:771-778
    • (2005) Neoplasia , vol.7 , pp. 771-778
    • Ebert, M.P.1    Mooney, S.H.2    Tonnes-Priddy, L.3
  • 37
    • 0034626988 scopus 로고    scopus 로고
    • Inactivation of the DNA-repair gene MGMT and the clinical response of gliomas to alkylating agents
    • 1:CAS:528:DC%2BD3cXosFOltLg%3D 11070098 10.1056/NEJM200011093431901
    • Esteller M, Garcia-Foncillas J, Andion E et al (2000) Inactivation of the DNA-repair gene MGMT and the clinical response of gliomas to alkylating agents. N Engl J Med 343:1350-1354
    • (2000) N Engl J Med , vol.343 , pp. 1350-1354
    • Esteller, M.1    Garcia-Foncillas, J.2    Andion, E.3
  • 38
    • 59349101857 scopus 로고    scopus 로고
    • Evaluation of MGMT Promoter methylation status and correlation with temozolomide response in orthotopic glioblastoma xenograft model
    • 1:CAS:528:DC%2BD1MXhtVGjtb0%3D 2790867 19011762 10.1007/s11060-008-9737-8
    • Kitange GJ, Carlson BL, Mladek AC et al (2009) Evaluation of MGMT Promoter methylation status and correlation with temozolomide response in orthotopic glioblastoma xenograft model. J Neurooncol 92:23-31
    • (2009) J Neurooncol , vol.92 , pp. 23-31
    • Kitange, G.J.1    Carlson, B.L.2    Mladek, A.C.3
  • 39
    • 0029829167 scopus 로고    scopus 로고
    • 6-methylguanine-DNA methytranseferase mRNA and its significance as indicator of selective chloroethylnitrosourea chemotherapy
    • 1:CAS:528:DyaK28Xnt1KgtLk%3D 8900378 10.1002/(SICI)1097-0215(19961021)69: 5<420: AID-IJC12>3.0.CO;2-6
    • 6-methylguanine-DNA methytranseferase mRNA and its significance as indicator of selective chloroethylnitrosourea chemotherapy. Int J Cancer 69:420-425
    • (1996) Int J Cancer , vol.69 , pp. 420-425
    • Mineura, K.1    Yanagisawa, T.2    Wantanabe, K.3
  • 40
    • 78650226575 scopus 로고    scopus 로고
    • Molecular classification of low-grade diffuse gliomas
    • 21075857 10.2353/ajpath.2010.100680
    • Kim YH, Nobusawa S, Mittelbronn M et al (2010) Molecular classification of low-grade diffuse gliomas. Am J Pathol 177:2708-2714
    • (2010) Am J Pathol , vol.177 , pp. 2708-2714
    • Kim, Y.H.1    Nobusawa, S.2    Mittelbronn, M.3
  • 41
    • 70249097408 scopus 로고    scopus 로고
    • Isocitrate dehydrogenase 1 codon 132 mutation is an important prognostic biomarker in gliomas
    • 10.1200/JCO.2009.21.9832
    • Sanoson M, Marie Y, Paris S et al (2009) Isocitrate dehydrogenase 1 codon 132 mutation is an important prognostic biomarker in gliomas. J Clin Oncol 27:4150-4154
    • (2009) J Clin Oncol , vol.27 , pp. 4150-4154
    • Sanoson, M.1    Marie, Y.2    Paris, S.3
  • 42
    • 70349653793 scopus 로고    scopus 로고
    • IDH1 mutations as molecular signature and predictive factor of secondary glioblastomas
    • 1:CAS:528:DC%2BD1MXhtF2ltbbL 19755387 10.1158/1078-0432.CCR-09-0715
    • Nobusawa S, Watanabe T, Kleihues P et al (2009) IDH1 mutations as molecular signature and predictive factor of secondary glioblastomas. Clin Cancer Res 15:6002-6007
    • (2009) Clin Cancer Res , vol.15 , pp. 6002-6007
    • Nobusawa, S.1    Watanabe, T.2    Kleihues, P.3
  • 43
    • 84864050066 scopus 로고    scopus 로고
    • IDH1 mutations as an early and consistent marker in low-grade astrocytomas WHO grade and their consecutive secondary high-grade gliomas
    • 10.1007/s11060-012-0844-1 1:CAS:528:DC%2BC38Xot1Oksbg%3D 22410704 10.1007/s11060-012-0844-1
    • Juratli TA, Kirsch M, Roble K et al (2012) IDH1 mutations as an early and consistent marker in low-grade astrocytomas WHO grade and their consecutive secondary high-grade gliomas. J Neurooncol 108:403-410. doi: 10.1007/s11060-012-0844-1
    • (2012) J Neurooncol , vol.108 , pp. 403-410
    • Juratli, T.A.1    Kirsch, M.2    Roble, K.3
  • 44
    • 60849115270 scopus 로고    scopus 로고
    • IDH1 and IDH2 mutations in gliomas
    • 1:CAS:528:DC%2BD1MXitFWru7o%3D 2820383 19228619 10.1056/NEJMoa0808710
    • Yan H, Parsons DW, Jin G et al (2009) IDH1 and IDH2 mutations in gliomas. N Engl J Med 360:765-773
    • (2009) N Engl J Med , vol.360 , pp. 765-773
    • Yan, H.1    Parsons, D.W.2    Jin, G.3
  • 45
    • 34247849498 scopus 로고    scopus 로고
    • Dobrovic A (2007) Methylation sensitive high resolution melting (MS-HRM): A new approach for sensitive and high-throughput assessment of methylation
    • 1874596 17289753 10.1093/nar/gkm013
    • Wojdacz TK (2007) Dobrovic A (2007) Methylation sensitive high resolution melting (MS-HRM): a new approach for sensitive and high-throughput assessment of methylation. Nucleic Acids Res 35:e41
    • (2007) Nucleic Acids Res , vol.35 , pp. 41
    • Wojdacz, T.K.1
  • 46
    • 77952550882 scopus 로고    scopus 로고
    • Rapid determination of AKAP12 promoter methylationn levels in peripheral blood using methylation-sensitive high resolution melting (MS-HRM) analysis: Application in colorectal cancer
    • 1:CAS:528:DC%2BC3cXlsFOjurY%3D 20227403 10.1016/j.cca.2010.03.003
    • Liu W, Guan M, Bing S et al (2010) Rapid determination of AKAP12 promoter methylationn levels in peripheral blood using methylation-sensitive high resolution melting (MS-HRM) analysis: application in colorectal cancer. Clin Chim Acta 411:940-946
    • (2010) Clin Chim Acta , vol.411 , pp. 940-946
    • Liu, W.1    Guan, M.2    Bing, S.3
  • 47
    • 33748485597 scopus 로고    scopus 로고
    • The promise of pharmacogenetics: Assessing the prospects for disease and patient stratification
    • 10.1016/j.shpsc.2006.06.002
    • Smart A, Martin P (2006) The promise of pharmacogenetics: assessing the prospects for disease and patient stratification. Stud Hist Philos Biol Biomed Sci 37:589-601
    • (2006) Stud Hist Philos Biol Biomed Sci , vol.37 , pp. 589-601
    • Smart, A.1    Martin, P.2
  • 48
    • 20444374483 scopus 로고    scopus 로고
    • Circulating tumour-derived DNA and RNA markers in blood: A tool for early detection, diagnostics, and follow-up?
    • 15949585 10.1016/j.lungcan.2004.12.008
    • Bremnes RM, Sirera R, Camps C (2005) Circulating tumour-derived DNA and RNA markers in blood: a tool for early detection, diagnostics, and follow-up? Lung Cancer 49(1):1-12
    • (2005) Lung Cancer , vol.49 , Issue.1 , pp. 1-12
    • Bremnes, R.M.1    Sirera, R.2    Camps, C.3
  • 49
    • 62149107439 scopus 로고    scopus 로고
    • Multimarker circulating DNA assay for assessing blood of prostate cancer patients
    • 1:CAS:528:DC%2BD1MXivFaqt70%3D 19131636 10.1373/clinchem.2008.108498
    • Sunami E, Shinozaki M, Higano CS et al (2009) Multimarker circulating DNA assay for assessing blood of prostate cancer patients. Clin Chem 55(3):559-567
    • (2009) Clin Chem , vol.55 , Issue.3 , pp. 559-567
    • Sunami, E.1    Shinozaki, M.2    Higano, C.S.3
  • 50
    • 84868271361 scopus 로고    scopus 로고
    • Circulating DNA and NSCLC: Old findings with new perspectives
    • Catarino R, Coelho A, Medeiros R (2012) Circulating DNA and NSCLC: old findings with new perspectives. J Thorac Dis 4(5): 442-443
    • (2012) J Thorac Dis , vol.4 , Issue.5 , pp. 442-443
    • Catarino, R.1    Coelho, A.2    Medeiros, R.3


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