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Volumn 37, Issue 2, 2014, Pages 77-84

Aging in the olfactory system

Author keywords

Adult neurogenesis; Aging; Odorant receptor; Olfactory cortex; Rostral migratory stream; Synaptic organization

Indexed keywords

AGING; CELL POPULATION; INTERNEURON; MORPHOLOGY; NERVOUS SYSTEM DEVELOPMENT; NONHUMAN; OLFACTORY BULB; OLFACTORY CORTEX; OLFACTORY EPITHELIUM; OLFACTORY SYSTEM; PRIORITY JOURNAL; REVIEW; RODENT; SENSORY STIMULATION; SMELLING; SUBVENTRICULAR ZONE;

EID: 84893649721     PISSN: 01662236     EISSN: 1878108X     Source Type: Journal    
DOI: 10.1016/j.tins.2013.11.004     Document Type: Review
Times cited : (109)

References (95)
  • 1
    • 58149458285 scopus 로고    scopus 로고
    • The chemical senses and nutrition in older adults
    • Murphy C. The chemical senses and nutrition in older adults. J. Nutr. Elder. 2008, 27:247-265.
    • (2008) J. Nutr. Elder. , vol.27 , pp. 247-265
    • Murphy, C.1
  • 2
    • 63049132176 scopus 로고    scopus 로고
    • The olfactory system and its disorders
    • Doty R.L. The olfactory system and its disorders. Semin. Neurol. 2009, 29:74-81.
    • (2009) Semin. Neurol. , vol.29 , pp. 74-81
    • Doty, R.L.1
  • 3
    • 4644294031 scopus 로고    scopus 로고
    • Aging results in reduced epidermal growth factor receptor signaling, diminished olfactory neurogenesis, and deficits in fine olfactory discrimination
    • Enwere E., et al. Aging results in reduced epidermal growth factor receptor signaling, diminished olfactory neurogenesis, and deficits in fine olfactory discrimination. J. Neurosci. 2004, 24:8354-8365.
    • (2004) J. Neurosci. , vol.24 , pp. 8354-8365
    • Enwere, E.1
  • 4
    • 84889570830 scopus 로고    scopus 로고
    • Alteration of olfactory perceptual learning and its cellular basis in aged mice
    • Moreno M., et al. Alteration of olfactory perceptual learning and its cellular basis in aged mice. Neurobiol. Aging 2013, 10.1016/j.neurobiolaging.2013.08.034.
    • (2013) Neurobiol. Aging
    • Moreno, M.1
  • 5
    • 62349099299 scopus 로고    scopus 로고
    • Impaired olfactory discrimination learning and decreased olfactory sensitivity in aged C57Bl/6 mice
    • Patel R.C., Larson J. Impaired olfactory discrimination learning and decreased olfactory sensitivity in aged C57Bl/6 mice. Neurobiol. Aging 2009, 30:829-837.
    • (2009) Neurobiol. Aging , vol.30 , pp. 829-837
    • Patel, R.C.1    Larson, J.2
  • 6
    • 84855778548 scopus 로고    scopus 로고
    • Behavioral and cellular markers of olfactory aging and their response to enrichment
    • Rey N.L., et al. Behavioral and cellular markers of olfactory aging and their response to enrichment. Neurobiol. Aging 2012, 33. 10.1016/j.neurobiolaging.2011.03.026.
    • (2012) Neurobiol. Aging , vol.33
    • Rey, N.L.1
  • 7
    • 84863434140 scopus 로고    scopus 로고
    • Age-associated loss of selectivity in human olfactory sensory neurons
    • Rawson N.E., et al. Age-associated loss of selectivity in human olfactory sensory neurons. Neurobiol. Aging 2012, 33:1913-1919.
    • (2012) Neurobiol. Aging , vol.33 , pp. 1913-1919
    • Rawson, N.E.1
  • 8
    • 50249134475 scopus 로고    scopus 로고
    • Principles of glomerular organization in the human olfactory bulb-implications for odor processing
    • Maresh A., et al. Principles of glomerular organization in the human olfactory bulb-implications for odor processing. PLoS ONE 2008, 3:e2640.
    • (2008) PLoS ONE , vol.3
    • Maresh, A.1
  • 9
    • 84884284902 scopus 로고    scopus 로고
    • Dendritic spine changes associated with normal aging
    • Dickstein D.L., et al. Dendritic spine changes associated with normal aging. Neuroscience 2013, 251:21-32.
    • (2013) Neuroscience , vol.251 , pp. 21-32
    • Dickstein, D.L.1
  • 10
    • 84858702953 scopus 로고    scopus 로고
    • The ageing cortical synapse: hallmarks and implications for cognitive decline
    • Morrison J.H., Baxter M.G. The ageing cortical synapse: hallmarks and implications for cognitive decline. Nat. Rev. Neurosci. 2012, 13:240-250.
    • (2012) Nat. Rev. Neurosci. , vol.13 , pp. 240-250
    • Morrison, J.H.1    Baxter, M.G.2
  • 11
    • 20344396658 scopus 로고    scopus 로고
    • Temporal profiling of gene expression during neurogenesis and remodeling in the olfactory epithelium at short intervals after target ablation
    • Getchell T.V., et al. Temporal profiling of gene expression during neurogenesis and remodeling in the olfactory epithelium at short intervals after target ablation. J. Neurosci. Res. 2005, 80:309-329.
    • (2005) J. Neurosci. Res. , vol.80 , pp. 309-329
    • Getchell, T.V.1
  • 12
    • 77955364920 scopus 로고    scopus 로고
    • Chromosomal location-dependent nonstochastic onset of odor receptor expression
    • Rodriguez-Gil D.J., et al. Chromosomal location-dependent nonstochastic onset of odor receptor expression. J. Neurosci. 2010, 30:10067-10075.
    • (2010) J. Neurosci. , vol.30 , pp. 10067-10075
    • Rodriguez-Gil, D.J.1
  • 13
    • 82955190505 scopus 로고    scopus 로고
    • Genetic and environmental influences on odor identification ability in the very old
    • Doty R.L., et al. Genetic and environmental influences on odor identification ability in the very old. Psychol. Aging 2011, 26:864-871.
    • (2011) Psychol. Aging , vol.26 , pp. 864-871
    • Doty, R.L.1
  • 14
    • 68649125846 scopus 로고    scopus 로고
    • Olfaction in aging and Alzheimer's disease: event-related potentials to a cross-modal odor-recognition memory task discriminate ApoE epsilon4+ and ApoE epsilon 4- individuals
    • Murphy C., et al. Olfaction in aging and Alzheimer's disease: event-related potentials to a cross-modal odor-recognition memory task discriminate ApoE epsilon4+ and ApoE epsilon 4- individuals. Ann. N. Y. Acad. Sci. 2009, 1170:647-657.
    • (2009) Ann. N. Y. Acad. Sci. , vol.1170 , pp. 647-657
    • Murphy, C.1
  • 15
    • 80155123438 scopus 로고    scopus 로고
    • Sensory network dysfunction, behavioral impairments, and their reversibility in an Alzheimer's beta-amyloidosis mouse model
    • Wesson D.W., et al. Sensory network dysfunction, behavioral impairments, and their reversibility in an Alzheimer's beta-amyloidosis mouse model. J. Neurosci. 2011, 31:15962-15971.
    • (2011) J. Neurosci. , vol.31 , pp. 15962-15971
    • Wesson, D.W.1
  • 16
    • 79959475090 scopus 로고    scopus 로고
    • Age-related changes of the regeneration mode in the mouse peripheral olfactory system following olfactotoxic drug methimazole-induced damage
    • Suzukawa K., et al. Age-related changes of the regeneration mode in the mouse peripheral olfactory system following olfactotoxic drug methimazole-induced damage. J. Comp. Neurol. 2011, 519:2154-2174.
    • (2011) J. Comp. Neurol. , vol.519 , pp. 2154-2174
    • Suzukawa, K.1
  • 17
    • 0021711343 scopus 로고
    • An autoradiographic study of the mouse olfactory epithelium: evidence for long-lived receptors
    • Hinds J.W., et al. An autoradiographic study of the mouse olfactory epithelium: evidence for long-lived receptors. Anat. Rec. 1984, 210:375-383.
    • (1984) Anat. Rec. , vol.210 , pp. 375-383
    • Hinds, J.W.1
  • 18
    • 0019867362 scopus 로고
    • Aging in the rat olfactory system: correlation of changes in the olfactory epithelium and olfactory bulb
    • Hinds J.W., McNelly N.A. Aging in the rat olfactory system: correlation of changes in the olfactory epithelium and olfactory bulb. J. Comp. Neurol. 1981, 203:441-453.
    • (1981) J. Comp. Neurol. , vol.203 , pp. 441-453
    • Hinds, J.W.1    McNelly, N.A.2
  • 19
    • 0030450939 scopus 로고    scopus 로고
    • The aging olfactory epithelium: neurogenesis, response to damage, and odorant-induced activity
    • Loo A.T., et al. The aging olfactory epithelium: neurogenesis, response to damage, and odorant-induced activity. Int. J. Dev. Neurosci. 1996, 14:881-900.
    • (1996) Int. J. Dev. Neurosci. , vol.14 , pp. 881-900
    • Loo, A.T.1
  • 20
    • 0030919646 scopus 로고    scopus 로고
    • Proliferation in the rat olfactory epithelium: age-dependent changes
    • Weiler E., Farbman A.I. Proliferation in the rat olfactory epithelium: age-dependent changes. J. Neurosci. 1997, 17:3610-3622.
    • (1997) J. Neurosci. , vol.17 , pp. 3610-3622
    • Weiler, E.1    Farbman, A.I.2
  • 21
    • 79961181178 scopus 로고    scopus 로고
    • Regulated reprogramming in the regeneration of sensory receptor cells
    • Bermingham-McDonogh O., Reh T.A. Regulated reprogramming in the regeneration of sensory receptor cells. Neuron 2011, 71:389-405.
    • (2011) Neuron , vol.71 , pp. 389-405
    • Bermingham-McDonogh, O.1    Reh, T.A.2
  • 22
    • 78449260733 scopus 로고    scopus 로고
    • Regeneration of new neurons is preserved in aged vomeronasal epithelia
    • Brann J.H., Firestein S. Regeneration of new neurons is preserved in aged vomeronasal epithelia. J. Neurosci. 2010, 30:15686-15694.
    • (2010) J. Neurosci. , vol.30 , pp. 15686-15694
    • Brann, J.H.1    Firestein, S.2
  • 23
    • 80052462396 scopus 로고    scopus 로고
    • Feedback regulation of neurogenesis in the mammalian olfactory epithelium: new insights from genetics and systems biology
    • CRC Press, A. Menini (Ed.)
    • Gokoffski K.K., et al. Feedback regulation of neurogenesis in the mammalian olfactory epithelium: new insights from genetics and systems biology. The Neurobiology of Olfaction 2010, CRC Press. http://www.ncbi.nlm.nih.gov/books/NBK55982/, A. Menini (Ed.).
    • (2010) The Neurobiology of Olfaction
    • Gokoffski, K.K.1
  • 24
    • 81155128111 scopus 로고    scopus 로고
    • Telomere shortening impairs regeneration of the olfactory epithelium in response to injury but not under homeostatic conditions
    • Watabe-Rudolph M., et al. Telomere shortening impairs regeneration of the olfactory epithelium in response to injury but not under homeostatic conditions. PLoS ONE 2011, 6:e27801.
    • (2011) PLoS ONE , vol.6
    • Watabe-Rudolph, M.1
  • 25
    • 0141834949 scopus 로고    scopus 로고
    • Age-related trends in gene expression in the chemosensory-nasal mucosae of senescence-accelerated mice
    • Getchell T.V., et al. Age-related trends in gene expression in the chemosensory-nasal mucosae of senescence-accelerated mice. Ageing Res. Rev. 2003, 2:211-243.
    • (2003) Ageing Res. Rev. , vol.2 , pp. 211-243
    • Getchell, T.V.1
  • 26
    • 0038454526 scopus 로고    scopus 로고
    • Age-related olfactory dysfunction: cellular and molecular characterization in the rat
    • Conley D.B., et al. Age-related olfactory dysfunction: cellular and molecular characterization in the rat. Am. J. Rhinol. 2003, 17:169-175.
    • (2003) Am. J. Rhinol. , vol.17 , pp. 169-175
    • Conley, D.B.1
  • 27
    • 77952126795 scopus 로고    scopus 로고
    • Age-related changes in cell dynamics of the postnatal mouse olfactory neuroepithelium: cell proliferation, neuronal differentiation, and cell death
    • Kondo K., et al. Age-related changes in cell dynamics of the postnatal mouse olfactory neuroepithelium: cell proliferation, neuronal differentiation, and cell death. J. Comp. Neurol. 2010, 518:1962-1975.
    • (2010) J. Comp. Neurol. , vol.518 , pp. 1962-1975
    • Kondo, K.1
  • 28
    • 77956183290 scopus 로고    scopus 로고
    • State-dependent sculpting of olfactory sensory neurons is attributed to sensory enrichment, odor deprivation, and aging
    • Cavallin M.A., et al. State-dependent sculpting of olfactory sensory neurons is attributed to sensory enrichment, odor deprivation, and aging. Neurosci. Lett. 2010, 483:90-95.
    • (2010) Neurosci. Lett. , vol.483 , pp. 90-95
    • Cavallin, M.A.1
  • 29
    • 4644251468 scopus 로고    scopus 로고
    • High-throughput microarray detection of olfactory receptor gene expression in the mouse
    • Zhang X., et al. High-throughput microarray detection of olfactory receptor gene expression in the mouse. Proc. Natl. Acad. Sci. U.S.A. 2004, 101:14168-14173.
    • (2004) Proc. Natl. Acad. Sci. U.S.A. , vol.101 , pp. 14168-14173
    • Zhang, X.1
  • 30
    • 70349509190 scopus 로고    scopus 로고
    • Expression patterns of odorant receptors and response properties of olfactory sensory neurons in aged mice
    • Lee A.C., et al. Expression patterns of odorant receptors and response properties of olfactory sensory neurons in aged mice. Chem. Senses 2009, 34:695-703.
    • (2009) Chem. Senses , vol.34 , pp. 695-703
    • Lee, A.C.1
  • 31
    • 84888132650 scopus 로고    scopus 로고
    • Temporal patterns of odorant receptor gene expression in adult and aged mice
    • Khan M., et al. Temporal patterns of odorant receptor gene expression in adult and aged mice. Mol. Cell. Neurosci. 2013, 10.1016/j.mcn.2013.08.001.
    • (2013) Mol. Cell. Neurosci.
    • Khan, M.1
  • 32
    • 0017350573 scopus 로고
    • Aging of the rat olfactory bulb: growth and atrophy of constituent layers and changes in size and number of mitral cells
    • Hinds J.W., McNelly N.A. Aging of the rat olfactory bulb: growth and atrophy of constituent layers and changes in size and number of mitral cells. J. Comp. Neurol. 1977, 72:345-367.
    • (1977) J. Comp. Neurol. , vol.72 , pp. 345-367
    • Hinds, J.W.1    McNelly, N.A.2
  • 33
    • 77957289349 scopus 로고    scopus 로고
    • Age-induced disruption of selective olfactory bulb synaptic circuits
    • Richard M.B., et al. Age-induced disruption of selective olfactory bulb synaptic circuits. Proc. Natl. Acad. Sci. U.S.A. 2010, 107:15613-15618.
    • (2010) Proc. Natl. Acad. Sci. U.S.A. , vol.107 , pp. 15613-15618
    • Richard, M.B.1
  • 34
    • 33745002263 scopus 로고    scopus 로고
    • Age-related changes in calretinin-immunoreactive periglomerular cells in the rat main olfactory bulb
    • Hwang I.K., et al. Age-related changes in calretinin-immunoreactive periglomerular cells in the rat main olfactory bulb. J. Vet. Med. Sci. 2006, 68:465-469.
    • (2006) J. Vet. Med. Sci. , vol.68 , pp. 465-469
    • Hwang, I.K.1
  • 35
    • 84875825967 scopus 로고    scopus 로고
    • Age-dependent regional changes in the rostral migratory stream
    • Mobley A.S., et al. Age-dependent regional changes in the rostral migratory stream. Neurobiol. Aging 2013, 34:1873-1881.
    • (2013) Neurobiol. Aging , vol.34 , pp. 1873-1881
    • Mobley, A.S.1
  • 36
    • 0037164605 scopus 로고    scopus 로고
    • Comparative study of aging in the mouse olfactory bulb
    • Mirich J.M., et al. Comparative study of aging in the mouse olfactory bulb. J. Comp. Neurol. 2002, 454:361-372.
    • (2002) J. Comp. Neurol. , vol.454 , pp. 361-372
    • Mirich, J.M.1
  • 37
    • 70349149472 scopus 로고    scopus 로고
    • Caspase-9 activation revealed by semaphorin 7A cleavage is independent of apoptosis in the aged olfactory bulb
    • Ohsawa S., et al. Caspase-9 activation revealed by semaphorin 7A cleavage is independent of apoptosis in the aged olfactory bulb. J. Neurosci. 2009, 29:11385-11392.
    • (2009) J. Neurosci. , vol.29 , pp. 11385-11392
    • Ohsawa, S.1
  • 38
    • 72849149367 scopus 로고    scopus 로고
    • Interneurons produced in adulthood are required for the normal functioning of the olfactory bulb network and for the execution of selected olfactory behaviors
    • Breton-Provencher V., et al. Interneurons produced in adulthood are required for the normal functioning of the olfactory bulb network and for the execution of selected olfactory behaviors. J. Neurosci. 2009, 29:15245-15257.
    • (2009) J. Neurosci. , vol.29 , pp. 15245-15257
    • Breton-Provencher, V.1
  • 39
    • 52949147794 scopus 로고    scopus 로고
    • Roles of continuous neurogenesis in the structural and functional integrity of the adult forebrain
    • Imayoshi I., et al. Roles of continuous neurogenesis in the structural and functional integrity of the adult forebrain. Nat. Neurosci. 2008, 11:1153-1161.
    • (2008) Nat. Neurosci. , vol.11 , pp. 1153-1161
    • Imayoshi, I.1
  • 40
    • 84857406555 scopus 로고    scopus 로고
    • Reduced proliferation in the adult mouse subventricular zone increases survival of olfactory bulb interneurons
    • Sui Y., et al. Reduced proliferation in the adult mouse subventricular zone increases survival of olfactory bulb interneurons. PLoS ONE 2012, 7:e31549.
    • (2012) PLoS ONE , vol.7
    • Sui, Y.1
  • 41
    • 78449252209 scopus 로고    scopus 로고
    • Ablation of mouse adult neurogenesis alters olfactory bulb structure and olfactory fear conditioning
    • Valley M.T., et al. Ablation of mouse adult neurogenesis alters olfactory bulb structure and olfactory fear conditioning. Front. Neurosci. 2009, 3:51.
    • (2009) Front. Neurosci. , vol.3 , pp. 51
    • Valley, M.T.1
  • 42
    • 29244439038 scopus 로고    scopus 로고
    • Neural plasticity in the ageing brain
    • Burke S.N., Barnes C.A. Neural plasticity in the ageing brain. Nat. Rev. Neurosci. 2006, 7:30-40.
    • (2006) Nat. Rev. Neurosci. , vol.7 , pp. 30-40
    • Burke, S.N.1    Barnes, C.A.2
  • 43
    • 79959395036 scopus 로고    scopus 로고
    • Long-term changes in the morphology and synaptic distributions of adult-born neurons
    • Livneh Y., Mizrahi A. Long-term changes in the morphology and synaptic distributions of adult-born neurons. J. Comp. Neurol. 2011, 519:2212-2224.
    • (2011) J. Comp. Neurol. , vol.519 , pp. 2212-2224
    • Livneh, Y.1    Mizrahi, A.2
  • 44
    • 33846108438 scopus 로고    scopus 로고
    • Odorant identification and quality perception following methyl bromide-induced lesions of the olfactory epithelium
    • Youngentob S.L., Schwob J.E. Odorant identification and quality perception following methyl bromide-induced lesions of the olfactory epithelium. Behav. Neurosci. 2006, 120:1346-1355.
    • (2006) Behav. Neurosci. , vol.120 , pp. 1346-1355
    • Youngentob, S.L.1    Schwob, J.E.2
  • 45
    • 47849120056 scopus 로고    scopus 로고
    • Origin and function of olfactory bulb interneuron diversity
    • Lledo P.M., et al. Origin and function of olfactory bulb interneuron diversity. Trends Neurosci. 2008, 31:392-400.
    • (2008) Trends Neurosci. , vol.31 , pp. 392-400
    • Lledo, P.M.1
  • 46
    • 69449091854 scopus 로고    scopus 로고
    • Blood vessels form a migratory scaffold in the rostral migratory stream
    • Whitman M.C., et al. Blood vessels form a migratory scaffold in the rostral migratory stream. J. Comp. Neurol. 2009, 516:94-104.
    • (2009) J. Comp. Neurol. , vol.516 , pp. 94-104
    • Whitman, M.C.1
  • 47
    • 84872185150 scopus 로고    scopus 로고
    • Regulation of endogenous neural stem/progenitor cells for neural repair-factors that promote neurogenesis and gliogenesis in the normal and damaged brain
    • Christie K.J., Turnley A.M. Regulation of endogenous neural stem/progenitor cells for neural repair-factors that promote neurogenesis and gliogenesis in the normal and damaged brain. Front. Cell. Neurosci. 2012, 6:70.
    • (2012) Front. Cell. Neurosci. , vol.6 , pp. 70
    • Christie, K.J.1    Turnley, A.M.2
  • 48
    • 78149470437 scopus 로고    scopus 로고
    • When neurogenesis encounters aging and disease
    • Lazarov O., et al. When neurogenesis encounters aging and disease. Trends Neurosci. 2010, 33:569-579.
    • (2010) Trends Neurosci. , vol.33 , pp. 569-579
    • Lazarov, O.1
  • 49
    • 0141447477 scopus 로고    scopus 로고
    • Neurogenesis and aging: FGF-2 and HB-EGF restore neurogenesis in hippocampus and subventricular zone of aged mice
    • Jin K., et al. Neurogenesis and aging: FGF-2 and HB-EGF restore neurogenesis in hippocampus and subventricular zone of aged mice. Aging Cell 2003, 2:175-183.
    • (2003) Aging Cell , vol.2 , pp. 175-183
    • Jin, K.1
  • 50
    • 65549125564 scopus 로고    scopus 로고
    • Neural stem and progenitor cells retain their potential for proliferation and differentiation into functional neurons despite lower number in aged brain
    • Ahlenius H., et al. Neural stem and progenitor cells retain their potential for proliferation and differentiation into functional neurons despite lower number in aged brain. J. Neurosci. 2009, 29:4408-4419.
    • (2009) J. Neurosci. , vol.29 , pp. 4408-4419
    • Ahlenius, H.1
  • 51
    • 78650679757 scopus 로고    scopus 로고
    • Aging of the subventricular zone neural stem cell niche: evidence for quiescence-associated changes between early and mid-adulthood
    • Bouab M., et al. Aging of the subventricular zone neural stem cell niche: evidence for quiescence-associated changes between early and mid-adulthood. Neuroscience 2011, 173:135-149.
    • (2011) Neuroscience , vol.173 , pp. 135-149
    • Bouab, M.1
  • 52
    • 1242341960 scopus 로고    scopus 로고
    • Neural stem cell detection, characterization, and age-related changes in the subventricular zone of mice
    • Maslov A.Y., et al. Neural stem cell detection, characterization, and age-related changes in the subventricular zone of mice. J. Neurosci. 2004, 24:1726-1733.
    • (2004) J. Neurosci. , vol.24 , pp. 1726-1733
    • Maslov, A.Y.1
  • 53
    • 84917674645 scopus 로고    scopus 로고
    • Aging of the subventricular zone neural stem cell niche
    • Conover J.C., Shook B.A. Aging of the subventricular zone neural stem cell niche. Aging Dis. 2011, 2:49-63.
    • (2011) Aging Dis. , vol.2 , pp. 49-63
    • Conover, J.C.1    Shook, B.A.2
  • 54
    • 33646943830 scopus 로고    scopus 로고
    • The aging neurogenic subventricular zone
    • Luo J., et al. The aging neurogenic subventricular zone. Aging Cell 2006, 5:139-152.
    • (2006) Aging Cell , vol.5 , pp. 139-152
    • Luo, J.1
  • 55
    • 77953081652 scopus 로고    scopus 로고
    • Peripheral growth hormone induces cell proliferation in the intact adult rat brain
    • David Aberg N., et al. Peripheral growth hormone induces cell proliferation in the intact adult rat brain. Growth Horm. IGF Res. 2010, 20:264-269.
    • (2010) Growth Horm. IGF Res. , vol.20 , pp. 264-269
    • David Aberg, N.1
  • 56
    • 0030826603 scopus 로고    scopus 로고
    • Transforming growth factor-alpha null and senescent mice show decreased neural progenitor cell proliferation in the forebrain subependyma
    • Tropepe V., et al. Transforming growth factor-alpha null and senescent mice show decreased neural progenitor cell proliferation in the forebrain subependyma. J. Neurosci. 1997, 17:7850-7859.
    • (1997) J. Neurosci. , vol.17 , pp. 7850-7859
    • Tropepe, V.1
  • 57
    • 47749088572 scopus 로고    scopus 로고
    • A diacylglycerol lipase-CB2 cannabinoid pathway regulates adult subventricular zone neurogenesis in an age-dependent manner
    • Goncalves M.B., et al. A diacylglycerol lipase-CB2 cannabinoid pathway regulates adult subventricular zone neurogenesis in an age-dependent manner. Mol. Cell. Neurosci. 2008, 38:526-536.
    • (2008) Mol. Cell. Neurosci. , vol.38 , pp. 526-536
    • Goncalves, M.B.1
  • 58
    • 83755206865 scopus 로고    scopus 로고
    • Overcoming the aging systemic milieu to restore neural stem cell function
    • Mendelsohn A.R., Larrick J.W. Overcoming the aging systemic milieu to restore neural stem cell function. Rejuvenation Res. 2011, 14:681-684.
    • (2011) Rejuvenation Res. , vol.14 , pp. 681-684
    • Mendelsohn, A.R.1    Larrick, J.W.2
  • 59
    • 84867753129 scopus 로고    scopus 로고
    • Mammalian target of rapamycin signaling is a key regulator of the transit-amplifying progenitor pool in the adult and aging forebrain
    • Paliouras G.N., et al. Mammalian target of rapamycin signaling is a key regulator of the transit-amplifying progenitor pool in the adult and aging forebrain. J. Neurosci. 2012, 32:15012-15026.
    • (2012) J. Neurosci. , vol.32 , pp. 15012-15026
    • Paliouras, G.N.1
  • 60
    • 80052410357 scopus 로고    scopus 로고
    • The ageing systemic milieu negatively regulates neurogenesis and cognitive function
    • Villeda S.A., et al. The ageing systemic milieu negatively regulates neurogenesis and cognitive function. Nature 2011, 477:90-94.
    • (2011) Nature , vol.477 , pp. 90-94
    • Villeda, S.A.1
  • 61
    • 84856650966 scopus 로고    scopus 로고
    • Astrocytes control the development of the migration-promoting vasculature scaffold in the postnatal brain via VEGF signaling
    • Bozoyan L., et al. Astrocytes control the development of the migration-promoting vasculature scaffold in the postnatal brain via VEGF signaling. J. Neurosci. 2012, 32:1687-1704.
    • (2012) J. Neurosci. , vol.32 , pp. 1687-1704
    • Bozoyan, L.1
  • 62
    • 73149120004 scopus 로고    scopus 로고
    • Different astroglia permissivity controls the migration of olfactory bulb interneuron precursors
    • Garcia-Marques J., et al. Different astroglia permissivity controls the migration of olfactory bulb interneuron precursors. Glia 2010, 58:218-230.
    • (2010) Glia , vol.58 , pp. 218-230
    • Garcia-Marques, J.1
  • 63
    • 70249105332 scopus 로고    scopus 로고
    • Adult neurogenesis and the olfactory system
    • Whitman M.C., Greer C.A. Adult neurogenesis and the olfactory system. Prog. Neurobiol. 2009, 89:162-175.
    • (2009) Prog. Neurobiol. , vol.89 , pp. 162-175
    • Whitman, M.C.1    Greer, C.A.2
  • 64
    • 84885025862 scopus 로고    scopus 로고
    • The generation of oligodendroglial cells is preserved in the rostral migratory stream during aging
    • Capilla-Gonzalez V., et al. The generation of oligodendroglial cells is preserved in the rostral migratory stream during aging. Front. Cell. Neurosci. 2013, 7:147.
    • (2013) Front. Cell. Neurosci. , vol.7 , pp. 147
    • Capilla-Gonzalez, V.1
  • 65
    • 80052384006 scopus 로고    scopus 로고
    • Involvement of newborn neurons in olfactory associative learning? The operant or non-operant component of the task makes all the difference
    • Mandairon N., et al. Involvement of newborn neurons in olfactory associative learning? The operant or non-operant component of the task makes all the difference. J. Neurosci. 2011, 31:12455-12460.
    • (2011) J. Neurosci. , vol.31 , pp. 12455-12460
    • Mandairon, N.1
  • 66
    • 84861851480 scopus 로고    scopus 로고
    • Parallel mitral and tufted cell pathways route distinct odor information to different targets in the olfactory cortex
    • Igarashi K.M., et al. Parallel mitral and tufted cell pathways route distinct odor information to different targets in the olfactory cortex. J. Neurosci. 2012, 32:7970-7985.
    • (2012) J. Neurosci. , vol.32 , pp. 7970-7985
    • Igarashi, K.M.1
  • 67
    • 81355161481 scopus 로고    scopus 로고
    • Genetic visualization of the secondary olfactory pathway in Tbx21 transgenic mice
    • Mitsui S., et al. Genetic visualization of the secondary olfactory pathway in Tbx21 transgenic mice. Neural Syst. Circuits 2011, 1:5.
    • (2011) Neural Syst. Circuits , vol.1 , pp. 5
    • Mitsui, S.1
  • 68
    • 0035791553 scopus 로고    scopus 로고
    • Age-related change of neuropeptide Y-immunoreactive neurons in the rat anterior olfactory nucleus
    • Hwang I.K., et al. Age-related change of neuropeptide Y-immunoreactive neurons in the rat anterior olfactory nucleus. J. Neurocytol. 2001, 30:967-972.
    • (2001) J. Neurocytol. , vol.30 , pp. 967-972
    • Hwang, I.K.1
  • 69
    • 84857275902 scopus 로고    scopus 로고
    • Propagation of tau pathology in a model of early Alzheimer's disease
    • de Calignon A., et al. Propagation of tau pathology in a model of early Alzheimer's disease. Neuron 2012, 73:685-697.
    • (2012) Neuron , vol.73 , pp. 685-697
    • de Calignon, A.1
  • 70
    • 62649098662 scopus 로고    scopus 로고
    • Age-related accumulation of Reelin in amyloid-like deposits
    • Knuesel I., et al. Age-related accumulation of Reelin in amyloid-like deposits. Neurobiol. Aging 2009, 30:697-716.
    • (2009) Neurobiol. Aging , vol.30 , pp. 697-716
    • Knuesel, I.1
  • 71
    • 78651480561 scopus 로고    scopus 로고
    • Cognitive decline is associated with reduced reelin expression in the entorhinal cortex of aged rats
    • Stranahan A.M., et al. Cognitive decline is associated with reduced reelin expression in the entorhinal cortex of aged rats. Cereb. Cortex 2011, 21:392-400.
    • (2011) Cereb. Cortex , vol.21 , pp. 392-400
    • Stranahan, A.M.1
  • 72
    • 1842505579 scopus 로고    scopus 로고
    • Olfactory dysfunction occurs in transgenic mice overexpressing human tau protein
    • Macknin J.B., et al. Olfactory dysfunction occurs in transgenic mice overexpressing human tau protein. Brain Res. 2004, 1000:174-178.
    • (2004) Brain Res. , vol.1000 , pp. 174-178
    • Macknin, J.B.1
  • 73
    • 79960863140 scopus 로고    scopus 로고
    • Doublecortin-expressing cells persist in the associative cerebral cortex and amygdala in aged nonhuman primates
    • Zhang X.M., et al. Doublecortin-expressing cells persist in the associative cerebral cortex and amygdala in aged nonhuman primates. Front. Neuroanat. 2009, 3:17.
    • (2009) Front. Neuroanat. , vol.3 , pp. 17
    • Zhang, X.M.1
  • 74
    • 3843073157 scopus 로고    scopus 로고
    • Subventricular zone-derived neuronal progenitors migrate into the subcortical forebrain of postnatal mice
    • De Marchis S., et al. Subventricular zone-derived neuronal progenitors migrate into the subcortical forebrain of postnatal mice. J. Comp. Neurol. 2004, 476:290-300.
    • (2004) J. Comp. Neurol. , vol.476 , pp. 290-300
    • De Marchis, S.1
  • 75
    • 84881546568 scopus 로고    scopus 로고
    • Age-dependent alterations in the number, volume, and localization of islands of Calleja within the olfactory tubercle
    • Adjei S., et al. Age-dependent alterations in the number, volume, and localization of islands of Calleja within the olfactory tubercle. Neurobiol. Aging 2013, 34:2676-2682.
    • (2013) Neurobiol. Aging , vol.34 , pp. 2676-2682
    • Adjei, S.1
  • 76
    • 84857922937 scopus 로고    scopus 로고
    • Increased hippocampal accumulation of autophagosomes predicts short-term recognition memory impairment in aged mice
    • Soontornniyomkij V., et al. Increased hippocampal accumulation of autophagosomes predicts short-term recognition memory impairment in aged mice. Age 2012, 34:305-316.
    • (2012) Age , vol.34 , pp. 305-316
    • Soontornniyomkij, V.1
  • 77
    • 79952968943 scopus 로고    scopus 로고
    • Odor fear conditioning modifies piriform cortex local field potentials both during conditioning and during post-conditioning sleep
    • Barnes D.C., et al. Odor fear conditioning modifies piriform cortex local field potentials both during conditioning and during post-conditioning sleep. PLoS ONE 2011, 6:e18130.
    • (2011) PLoS ONE , vol.6
    • Barnes, D.C.1
  • 78
    • 80053598576 scopus 로고    scopus 로고
    • Recurrent circuitry dynamically shapes the activation of piriform cortex
    • Franks K.M., et al. Recurrent circuitry dynamically shapes the activation of piriform cortex. Neuron 2011, 72:49-56.
    • (2011) Neuron , vol.72 , pp. 49-56
    • Franks, K.M.1
  • 79
    • 80053596608 scopus 로고    scopus 로고
    • A major role for intracortical circuits in the strength and tuning of odor-evoked excitation in olfactory cortex
    • Poo C., Isaacson J.S. A major role for intracortical circuits in the strength and tuning of odor-evoked excitation in olfactory cortex. Neuron 2011, 72:41-48.
    • (2011) Neuron , vol.72 , pp. 41-48
    • Poo, C.1    Isaacson, J.S.2
  • 80
    • 84862703885 scopus 로고    scopus 로고
    • Odor representations in olfactory cortex: distributed rate coding and decorrelated population activity
    • Miura K., et al. Odor representations in olfactory cortex: distributed rate coding and decorrelated population activity. Neuron 2012, 74:1087-1098.
    • (2012) Neuron , vol.74 , pp. 1087-1098
    • Miura, K.1
  • 81
    • 76149100260 scopus 로고    scopus 로고
    • Single-unit activity in piriform cortex during slow-wave state is shaped by recent odor experience
    • Wilson D.A. Single-unit activity in piriform cortex during slow-wave state is shaped by recent odor experience. J. Neurosci. 2010, 30:1760-1765.
    • (2010) J. Neurosci. , vol.30 , pp. 1760-1765
    • Wilson, D.A.1
  • 82
    • 0021874770 scopus 로고
    • Aging in the rat olfactory system: relative stability of piriform cortex contrasts with changes in olfactory bulb and olfactory epithelium
    • Curcio C.A., et al. Aging in the rat olfactory system: relative stability of piriform cortex contrasts with changes in olfactory bulb and olfactory epithelium. J. Comp. Neurol. 1985, 235:519-528.
    • (1985) J. Comp. Neurol. , vol.235 , pp. 519-528
    • Curcio, C.A.1
  • 83
    • 84883526679 scopus 로고    scopus 로고
    • Evidence for loss of synaptic AMPA receptors in anterior piriform cortex of aged mice
    • Gocel J., Larson J. Evidence for loss of synaptic AMPA receptors in anterior piriform cortex of aged mice. Front. Aging Neurosci. 2013, 5:39.
    • (2013) Front. Aging Neurosci. , vol.5 , pp. 39
    • Gocel, J.1    Larson, J.2
  • 84
    • 79959891730 scopus 로고    scopus 로고
    • How is the olfactory map formed and interpreted in the mammalian brain?
    • Mori K., Sakano H. How is the olfactory map formed and interpreted in the mammalian brain?. Annu. Rev. Neurosci. 2011, 34:467-499.
    • (2011) Annu. Rev. Neurosci. , vol.34 , pp. 467-499
    • Mori, K.1    Sakano, H.2
  • 85
    • 0026773289 scopus 로고
    • Human olfactory biopsy. The influence of age and receptor distribution
    • Paik S.I., et al. Human olfactory biopsy. The influence of age and receptor distribution. Arch. Otolaryngol. Head Neck Surg. 1992, 118:731-738.
    • (1992) Arch. Otolaryngol. Head Neck Surg. , vol.118 , pp. 731-738
    • Paik, S.I.1
  • 86
    • 0019160626 scopus 로고
    • An assessment of olfactory deficits in patients with damage to prefrontal cortex
    • Potter H., Butters N. An assessment of olfactory deficits in patients with damage to prefrontal cortex. Neuropsychologia 1980, 18:621-628.
    • (1980) Neuropsychologia , vol.18 , pp. 621-628
    • Potter, H.1    Butters, N.2
  • 87
    • 67651174271 scopus 로고    scopus 로고
    • Age-related differences in the neural substrates of cross-modal olfactory recognition memory: an fMRI investigation
    • Cerf-Ducastel B., Murphy C. Age-related differences in the neural substrates of cross-modal olfactory recognition memory: an fMRI investigation. Brain Res. 2009, 1285:88-98.
    • (2009) Brain Res. , vol.1285 , pp. 88-98
    • Cerf-Ducastel, B.1    Murphy, C.2
  • 88
    • 81355164009 scopus 로고    scopus 로고
    • Cortical processing of odor objects
    • Wilson D.A., Sullivan R.M. Cortical processing of odor objects. Neuron 2011, 72:506-519.
    • (2011) Neuron , vol.72 , pp. 506-519
    • Wilson, D.A.1    Sullivan, R.M.2
  • 89
    • 77957204389 scopus 로고    scopus 로고
    • The behavioral relevance of multisensory neural response interactions
    • Sperdin H.F., et al. The behavioral relevance of multisensory neural response interactions. Front. Neurosci. 2010, 4:9.
    • (2010) Front. Neurosci. , vol.4 , pp. 9
    • Sperdin, H.F.1
  • 90
    • 77649127620 scopus 로고    scopus 로고
    • Smelling sounds: olfactory-auditory sensory convergence in the olfactory tubercle
    • Wesson D.W., Wilson D.A. Smelling sounds: olfactory-auditory sensory convergence in the olfactory tubercle. J. Neurosci. 2010, 30:3013-3021.
    • (2010) J. Neurosci. , vol.30 , pp. 3013-3021
    • Wesson, D.W.1    Wilson, D.A.2
  • 91
    • 84881499965 scopus 로고    scopus 로고
    • Lateral entorhinal modulation of piriform cortical activity and fine odor discrimination
    • Chapuis J., et al. Lateral entorhinal modulation of piriform cortical activity and fine odor discrimination. J. Neurosci. 2013, 33:13449-13459.
    • (2013) J. Neurosci. , vol.33 , pp. 13449-13459
    • Chapuis, J.1
  • 92
    • 70349617701 scopus 로고    scopus 로고
    • Spared and impaired olfactory abilities after thalamic lesions
    • Sela L., et al. Spared and impaired olfactory abilities after thalamic lesions. J. Neurosci. 2009, 29:12059-12069.
    • (2009) J. Neurosci. , vol.29 , pp. 12059-12069
    • Sela, L.1
  • 93
    • 0034192472 scopus 로고    scopus 로고
    • Olfactory event-related potentials and aging: normative data
    • Murphy C., et al. Olfactory event-related potentials and aging: normative data. Int. J. Psychophysiol. 2000, 36:133-145.
    • (2000) Int. J. Psychophysiol. , vol.36 , pp. 133-145
    • Murphy, C.1
  • 94
    • 84875625129 scopus 로고    scopus 로고
    • Mouse models of age-related mitochondrial neurosensory hearing loss
    • Han C., Someya S. Mouse models of age-related mitochondrial neurosensory hearing loss. Mol. Cell. Neurosci. 2013, 55:95-100.
    • (2013) Mol. Cell. Neurosci. , vol.55 , pp. 95-100
    • Han, C.1    Someya, S.2
  • 95
    • 33846822013 scopus 로고    scopus 로고
    • Aging of the somatosensory system: a translational perspective
    • Shaffer S.W., Harrison A.L. Aging of the somatosensory system: a translational perspective. Phys. Ther. 2007, 87:193-207.
    • (2007) Phys. Ther. , vol.87 , pp. 193-207
    • Shaffer, S.W.1    Harrison, A.L.2


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