-
1
-
-
79957899067
-
Digging deeper into obesity
-
Ahima RS. Digging deeper into obesity. J Clin Invest 121: 2076-2079, 2011.
-
(2011)
J Clin Invest
, vol.121
, pp. 2076-2079
-
-
Ahima, R.S.1
-
2
-
-
0037155132
-
Active Rho kinase (ROK-alpha) associates with insulin receptor substrate-1 and inhibits insulin signaling in vascular smooth muscle cells
-
Begum N, Sandu OA, Ito M, Lohmann SM, Smolenski A. Active Rho kinase (ROK-alpha) associates with insulin receptor substrate-1 and inhibits insulin signaling in vascular smooth muscle cells. J Biol Chem 277: 6214-6222, 2002.
-
(2002)
J Biol Chem
, vol.277
, pp. 6214-6222
-
-
Begum, N.1
Sandu, O.A.2
Ito, M.3
Lohmann, S.M.4
Smolenski, A.5
-
3
-
-
0036068133
-
Adipose tissue selective insulin receptor knockout protects against obesity and obesity-related glucose intolerance
-
Bluher M, Michael MD, Peroni OD, Ueki K, Carter N, Kahn BB, Kahn CR. Adipose tissue selective insulin receptor knockout protects against obesity and obesity-related glucose intolerance. Dev Cell 3: 25-38, 2002.
-
(2002)
Dev Cell
, vol.3
, pp. 25-38
-
-
Bluher, M.1
Michael, M.D.2
Peroni, O.D.3
Ueki, K.4
Carter, N.5
Kahn, B.B.6
Kahn, C.R.7
-
4
-
-
0347989317
-
Brown adipose tissue: Function and physiological significance
-
Cannon B, Nedergaard J. Brown adipose tissue: function and physiological significance. Physiol Rev 84: 277-359, 2004.
-
(2004)
Physiol Rev
, vol.84
, pp. 277-359
-
-
Cannon, B.1
Nedergaard, J.2
-
5
-
-
80355133234
-
Macrophage-mediated inflammation in metabolic disease
-
Chawla A, Nguyen KD, Goh YP. Macrophage-mediated inflammation in metabolic disease. Nat Rev Immunol 11: 738-749, 2011.
-
(2011)
Nat Rev Immunol
, vol.11
, pp. 738-749
-
-
Chawla, A.1
Nguyen, K.D.2
Goh, Y.P.3
-
6
-
-
79953304737
-
Novel pathway of adipogenesis through cross-talk between adipose tissue macrophages, adipose stem cells and adipocytes: Evidence of cell plasticity
-
Chazenbalk G, Bertolotto C, Heneidi S, Jumabay M, Trivax B, Aronowitz J, Yoshimura K, Simmons CF, Dumesic DA, Azziz R. Novel pathway of adipogenesis through cross-talk between adipose tissue macrophages, adipose stem cells and adipocytes: evidence of cell plasticity. PLoS One 6: e17834, 2011.
-
(2011)
PLoS One
, vol.6
-
-
Chazenbalk, G.1
Bertolotto, C.2
Heneidi, S.3
Jumabay, M.4
Trivax, B.5
Aronowitz, J.6
Yoshimura, K.7
Simmons, C.F.8
Dumesic, D.A.9
Azziz, R.10
-
7
-
-
84859412056
-
Regulation of glucose transport by ROCK1 differs from that of ROCK2 and is controlled by actin polymerization
-
Chun KH, Araki K, Jee Y, Lee DH, Oh BC, Huang H, Park KS, Lee SW, Zabolotny JM, Kim YB. Regulation of glucose transport by ROCK1 differs from that of ROCK2 and is controlled by actin polymerization. Endocrinology 153: 1649-1662, 2012.
-
(2012)
Endocrinology
, vol.153
, pp. 1649-1662
-
-
Chun, K.H.1
Araki, K.2
Jee, Y.3
Lee, D.H.4
Oh, B.C.5
Huang, H.6
Park, K.S.7
Lee, S.W.8
Zabolotny, J.M.9
Kim, Y.B.10
-
8
-
-
79952129518
-
In vivo activation of ROCK1 by insulin is impaired in skeletal muscle of humans with type 2 diabetes
-
Chun KH, Choi KD, Lee DH, Jung Y, Henry RR, Ciaraldi TP, Kim YB. In vivo activation of ROCK1 by insulin is impaired in skeletal muscle of humans with type 2 diabetes. Am J Physiol Endocrinol Metab 300: E536-E542, 2011.
-
(2011)
Am J Physiol Endocrinol Metab
, vol.300
-
-
Chun, K.H.1
Choi, K.D.2
Lee, D.H.3
Jung, Y.4
Henry, R.R.5
Ciaraldi, T.P.6
Kim, Y.B.7
-
9
-
-
0030724591
-
Pathogenesis of type 2 diabetes: Metabolic and molecular implications for identifying diabetes
-
DeFronzo RA. Pathogenesis of type 2 diabetes: metabolic and molecular implications for identifying diabetes. Diabetes Rev 5: 177-269, 1997.
-
(1997)
Diabetes Rev
, vol.5
, pp. 177-269
-
-
DeFronzo, R.A.1
-
10
-
-
79952155359
-
Transcriptional control of adipose lipid handling by IRF4
-
Eguchi J, Wang X, Yu S, Kershaw EE, Chiu PC, Dushay J, Estall JL, Klein U, Maratos-Flier E, Rosen ED. Transcriptional control of adipose lipid handling by IRF4. Cell Metab 13: 249-259, 2011.
-
(2011)
Cell Metab
, vol.13
, pp. 249-259
-
-
Eguchi, J.1
Wang, X.2
Yu, S.3
Kershaw, E.E.4
Chiu, P.C.5
Dushay, J.6
Estall, J.L.7
Klein, U.8
Maratos-Flier, E.9
Rosen, E.D.10
-
11
-
-
84856487711
-
Prevalence of obesity and trends in the distribution of body mass index among US adults, 1999-2010
-
Flegal KM, Carroll MD, Kit BK, Ogden CL. Prevalence of obesity and trends in the distribution of body mass index among US adults, 1999-2010. JAMA 307: 491-497, 2012.
-
(2012)
JAMA
, vol.307
, pp. 491-497
-
-
Flegal, K.M.1
Carroll, M.D.2
Kit, B.K.3
Ogden, C.L.4
-
12
-
-
25144500035
-
Role of Rho-kinase in regulation of insulin action and glucose homeostasis
-
Furukawa N, Ongusaha P, Jahng WJ, Araki K, Choi CS, Kim HJ, Lee YH, Kaibuchi K, Kahn BB, Masuzaki H, Kim JK, Lee SW, Kim YB. Role of Rho-kinase in regulation of insulin action and glucose homeostasis. Cell Metab 2: 119-129, 2005.
-
(2005)
Cell Metab
, vol.2
, pp. 119-129
-
-
Furukawa, N.1
Ongusaha, P.2
Jahng, W.J.3
Araki, K.4
Choi, C.S.5
Kim, H.J.6
Lee, Y.H.7
Kaibuchi, K.8
Kahn, B.B.9
Masuzaki, H.10
Kim, J.K.11
Lee, S.W.12
Kim, Y.B.13
-
13
-
-
77950361100
-
Protein kinase G controls brown fat cell differentiation and mitochondrial biogenesis
-
Haas B, Mayer P, Jennissen K, Scholz D, Berriel Diaz M, Bloch W, Herzig S, Fassler R, Pfeifer A. Protein kinase G controls brown fat cell differentiation and mitochondrial biogenesis. Sci Signal 2: ra78, 2009.
-
(2009)
Sci Signal
, vol.2
-
-
Haas, B.1
Mayer, P.2
Jennissen, K.3
Scholz, D.4
Berriel Diaz, M.5
Bloch, W.6
Herzig, S.7
Fassler, R.8
Pfeifer, A.9
-
14
-
-
79251468752
-
Rho and Rho-kinase activity in adipocytes contributes to a vicious cycle in obesity that may involve mechanical stretch
-
Hara Y, Wakino S, Tanabe Y, Saito M, Tokuyama H, Washida N, Tatematsu S, Yoshioka K, Homma K, Hasegawa K, Minakuchi H, Fujimura K, Hosoya K, Hayashi K, Nakayama K, Itoh H. Rho and Rho-kinase activity in adipocytes contributes to a vicious cycle in obesity that may involve mechanical stretch. Sci Signal 4: ra3, 2011.
-
(2011)
Sci Signal
, vol.4
-
-
Hara, Y.1
Wakino, S.2
Tanabe, Y.3
Saito, M.4
Tokuyama, H.5
Washida, N.6
Tatematsu, S.7
Yoshioka, K.8
Homma, K.9
Hasegawa, K.10
Minakuchi, H.11
Fujimura, K.12
Hosoya, K.13
Hayashi, K.14
Nakayama, K.15
Itoh, H.16
-
15
-
-
84859921736
-
A novel ChREBP isoform in adipose tissue regulates systemic glucose metabolism
-
Herman MA, Peroni OD, Villoria J, Schon MR, Abumrad NA, Bluher M, Klein S, Kahn BB. A novel ChREBP isoform in adipose tissue regulates systemic glucose metabolism. Nature 484: 333-338, 2012.
-
(2012)
Nature
, vol.484
, pp. 333-338
-
-
Herman, M.A.1
Peroni, O.D.2
Villoria, J.3
Schon, M.R.4
Abumrad, N.A.5
Bluher, M.6
Klein, S.7
Kahn, B.B.8
-
16
-
-
23644453653
-
Rho kinase as potential therapeutic target for cardiovascular diseases: Opportunities and challenges
-
Hu E, Lee D. Rho kinase as potential therapeutic target for cardiovascular diseases: opportunities and challenges. Expert Opin Ther Targets 9: 715-736, 2005.
-
(2005)
Expert Opin Ther Targets
, vol.9
, pp. 715-736
-
-
Hu, E.1
Lee, D.2
-
17
-
-
84866735424
-
Rho-kinase regulates energy balance by targeting hypothalamic leptin receptor signaling
-
Huang H, Kong D, Byun K, Ye C, Koda S, Lee D, Oh B, Lee S, Lee B, Zabolotny J, Kim M, Bjorbaek C, Lowell B, Kim Y. Rho-kinase regulates energy balance by targeting hypothalamic leptin receptor signaling. Nat Neurosci 15: 1391-1398, 2012.
-
(2012)
Nat Neurosci
, vol.15
, pp. 1391-1398
-
-
Huang, H.1
Kong, D.2
Byun, K.3
Ye, C.4
Koda, S.5
Lee, D.6
Oh, B.7
Lee, S.8
Lee, B.9
Zabolotny, J.10
Kim, M.11
Bjorbaek, C.12
Lowell, B.13
Kim, Y.14
-
18
-
-
84884412641
-
Metabolic actions of Rho-kinase in periphery and brain
-
Huang H, Lee DH, Zabolotny JM, Kim YB. Metabolic actions of Rho-kinase in periphery and brain. Trends Endocrinol Metab 24: 506-514, 2013.
-
(2013)
Trends Endocrinol Metab
, vol.24
, pp. 506-514
-
-
Huang, H.1
Lee, D.H.2
Zabolotny, J.M.3
Kim, Y.B.4
-
19
-
-
84884677127
-
ROCK1 in AgRP neurons regulates energy expenditure and locomotor activity in male mice
-
Huang H, Lee SH, Ye C, Lima IS, Oh BC, Lowell BB, Zabolotny JM, Kim YB. ROCK1 in AgRP neurons regulates energy expenditure and locomotor activity in male mice. Endocrinology 154: 3660-3670, 2013.
-
(2013)
Endocrinology
, vol.154
, pp. 3660-3670
-
-
Huang, H.1
Lee, S.H.2
Ye, C.3
Lima, I.S.4
Oh, B.C.5
Lowell, B.B.6
Zabolotny, J.M.7
Kim, Y.B.8
-
20
-
-
0037300437
-
Tissue-specific impairment of insulin signaling in vasculature and skeletal muscle of fructose-fed rats
-
Hyakukoku M, Higashiura K, Ura N, Murakami H, Yamaguchi K, Wang L, Furuhashi M, Togashi N, Shimamoto K. Tissue-specific impairment of insulin signaling in vasculature and skeletal muscle of fructose-fed rats. Hypertens Res 26: 169-176, 2003.
-
(2003)
Hypertens Res
, vol.26
, pp. 169-176
-
-
Hyakukoku, M.1
Higashiura, K.2
Ura, N.3
Murakami, H.4
Yamaguchi, K.5
Wang, L.6
Furuhashi, M.7
Togashi, N.8
Shimamoto, K.9
-
21
-
-
9244220646
-
The small GTP-binding protein Rho binds to and activates a 160 kDa Ser/Thr protein kinase homologous to myotonic dystrophy kinase
-
Ishizaki T, Maekawa M, Fujisawa K, Okawa K, Iwamatsu A, Fujita A, Watanabe N, Saito Y, Kakizuka A, Morii N, Narumiya S. The small GTP-binding protein Rho binds to and activates a 160 kDa Ser/Thr protein kinase homologous to myotonic dystrophy kinase. EMBO J 15: 1885-1893, 1996.
-
(1996)
EMBO J
, vol.15
, pp. 1885-1893
-
-
Ishizaki, T.1
Maekawa, M.2
Fujisawa, K.3
Okawa, K.4
Iwamatsu, A.5
Fujita, A.6
Watanabe, N.7
Saito, Y.8
Kakizuka, A.9
Morii, N.10
Narumiya, S.11
-
22
-
-
33748290317
-
Functional proteomics identifies protein-tyrosine phosphatase 1B as a target of RhoA signaling
-
Kabuyama Y, Langer SJ, Polvinen K, Homma Y, Resing KA, Ahn NG. Functional proteomics identifies protein-tyrosine phosphatase 1B as a target of RhoA signaling. Mol Cell Proteomics 5: 1359-1367, 2006.
-
(2006)
Mol Cell Proteomics
, vol.5
, pp. 1359-1367
-
-
Kabuyama, Y.1
Langer, S.J.2
Polvinen, K.3
Homma, Y.4
Resing, K.A.5
Ahn, N.G.6
-
23
-
-
0032489358
-
Type 2 diabetes: When insulin secretion fails to compensate for insulin resistance
-
Kahn BB. Type 2 diabetes: when insulin secretion fails to compensate for insulin resistance. Cell 92: 593-596, 1998.
-
(1998)
Cell
, vol.92
, pp. 593-596
-
-
Kahn, B.B.1
-
24
-
-
30744440948
-
Rho-kinase as a molecular target for insulin resistance and hypertension
-
Kanda T, Wakino S, Homma K, Yoshioka K, Tatematsu S, Hasegawa K, Takamatsu I, Sugano N, Hayashi K, Saruta T. Rho-kinase as a molecular target for insulin resistance and hypertension. FASEB J 20: 169-171, 2006.
-
(2006)
FASEB J
, vol.20
, pp. 169-171
-
-
Kanda, T.1
Wakino, S.2
Homma, K.3
Yoshioka, K.4
Tatematsu, S.5
Hasegawa, K.6
Takamatsu, I.7
Sugano, N.8
Hayashi, K.9
Saruta, T.10
-
25
-
-
33845764280
-
H-89 potentiates adipogenesis in 3T3-L1 cells by activating insulin signaling independently of protein kinase A
-
Kato Y, Ozaki N, Yamada T, Miura Y, Oiso Y. H-89 potentiates adipogenesis in 3T3-L1 cells by activating insulin signaling independently of protein kinase A. Life Sci 80: 476-483, 2007.
-
(2007)
Life Sci
, vol.80
, pp. 476-483
-
-
Kato, Y.1
Ozaki, N.2
Yamada, T.3
Miura, Y.4
Oiso, Y.5
-
26
-
-
33947364443
-
A Rho-kinase inhibitor, fasudil, prevents development of diabetes and nephropathy in insulinresistant diabetic rats
-
Kikuchi Y, Yamada M, Imakiire T, Kushiyama T, Higashi K, Hyodo N, Yamamoto K, Oda T, Suzuki S, Miura S. A Rho-kinase inhibitor, fasudil, prevents development of diabetes and nephropathy in insulinresistant diabetic rats. J Endocrinol 192: 595-603, 2007.
-
(2007)
J Endocrinol
, vol.192
, pp. 595-603
-
-
Kikuchi, Y.1
Yamada, M.2
Imakiire, T.3
Kushiyama, T.4
Higashi, K.5
Hyodo, N.6
Yamamoto, K.7
Oda, T.8
Suzuki, S.9
Miura, S.10
-
27
-
-
0037031893
-
Fatty acid infusion selectively impairs insulin action on Akt1 and protein kinase C lambda/zeta but not on glycogen synthase kinase-3
-
Kim YB, Shulman GI, Kahn BB. Fatty acid infusion selectively impairs insulin action on Akt1 and protein kinase C lambda/zeta but not on glycogen synthase kinase-3. J Biol Chem 277: 32915-32922, 2002.
-
(2002)
J Biol Chem
, vol.277
, pp. 32915-32922
-
-
Kim, Y.B.1
Shulman, G.I.2
Kahn, B.B.3
-
28
-
-
0033942614
-
Increased energy expenditure, decreased adiposity, and tissue-specific insulin sensitivity in protein-tyrosine phosphatase 1B-deficient mice
-
Klaman LD, Boss O, Peroni OD, Kim JK, Martino JL, Zabolotny JM, Moghal N, Lubkin M, Kim YB, Sharpe AH, Stricker-Krongrad A, Shulman GI, Neel BG, Kahn BB. Increased energy expenditure, decreased adiposity, and tissue-specific insulin sensitivity in protein-tyrosine phosphatase 1B-deficient mice. Mol Cell Biol 20: 5479-5489, 2000.
-
(2000)
Mol Cell Biol
, vol.20
, pp. 5479-5489
-
-
Klaman, L.D.1
Boss, O.2
Peroni, O.D.3
Kim, J.K.4
Martino, J.L.5
Zabolotny, J.M.6
Moghal, N.7
Lubkin, M.8
Kim, Y.B.9
Sharpe, A.H.10
Stricker-Krongrad, A.11
Shulman, G.I.12
Neel, B.G.13
Kahn, B.B.14
-
29
-
-
40949137434
-
Targeting of RhoA/ROCK signaling ameliorates progression of diabetic nephropathy independent of glucose control
-
Kolavennu V, Zeng L, Peng H, Wang Y, Danesh FR. Targeting of RhoA/ROCK signaling ameliorates progression of diabetic nephropathy independent of glucose control. Diabetes 57: 714-723, 2008.
-
(2008)
Diabetes
, vol.57
, pp. 714-723
-
-
Kolavennu, V.1
Zeng, L.2
Peng, H.3
Wang, Y.4
Danesh, F.R.5
-
30
-
-
56249108377
-
Intracellular lipid accumulation in liver and muscle and the insulin resistance syndrome
-
Lara-Castro C, Garvey WT. Intracellular lipid accumulation in liver and muscle and the insulin resistance syndrome. Endocrinol Metab Clin North Am 37: 841-856, 2008.
-
(2008)
Endocrinol Metab Clin North Am
, vol.37
, pp. 841-856
-
-
Lara-Castro, C.1
Garvey, W.T.2
-
31
-
-
66449126949
-
Targeted disruption of ROCK1 causes insulin resistance in vivo
-
Lee DH, Shi J, Jeoung NH, Kim MS, Zabolotny JM, Lee SW, White MF, Wei L, Kim YB. Targeted disruption of ROCK1 causes insulin resistance in vivo. J Biol Chem 284: 11776-11780, 2009.
-
(2009)
J Biol Chem
, vol.284
, pp. 11776-11780
-
-
Lee, D.H.1
Shi, J.2
Jeoung, N.H.3
Kim, M.S.4
Zabolotny, J.M.5
Lee, S.W.6
White, M.F.7
Wei, L.8
Kim, Y.B.9
-
32
-
-
67649336911
-
Extracellular matrix controls insulin signaling in mammary epithelial cells through the RhoA/Rok pathway
-
Lee YJ, Hsu TC, Du JY, Valentijn AJ, Wu TY, Cheng CF, Yang Z, Streuli CH. Extracellular matrix controls insulin signaling in mammary epithelial cells through the RhoA/Rok pathway. J Cell Physiol 220: 476-484, 2009.
-
(2009)
J Cell Physiol
, vol.220
, pp. 476-484
-
-
Lee, Y.J.1
Hsu, T.C.2
Du, J.Y.3
Valentijn, A.J.4
Wu, T.Y.5
Cheng, C.F.6
Yang, Z.7
Streuli, C.H.8
-
33
-
-
0028863142
-
A novel serine/threonine kinase binding the Ras-related RhoA GTPase which translocates the kinase to peripheral membranes
-
Leung T, Manser E, Tan L, Lim L. A novel serine/threonine kinase binding the Ras-related RhoA GTPase which translocates the kinase to peripheral membranes. J Biol Chem 270: 29051-29054, 1995.
-
(1995)
J Biol Chem
, vol.270
, pp. 29051-29054
-
-
Leung, T.1
Manser, E.2
Tan, L.3
Lim, L.4
-
34
-
-
0029062839
-
Transcriptional regulation of gene expression during adipocyte differentiation
-
MacDougald OA, Lane MD. Transcriptional regulation of gene expression during adipocyte differentiation. Annu Rev Biochem 64: 345-373, 1995.
-
(1995)
Annu Rev Biochem
, vol.64
, pp. 345-373
-
-
McDougald, O.A.1
Lane, M.D.2
-
35
-
-
9244257348
-
Rho-associated kinase, a novel serine/threonine kinase, as a putative target for small GTP binding protein Rho
-
Matsui T, Amano M, Yamamoto T, Chihara K, Nakafuku M, Ito M, Nakano T, Okawa K, Iwamatsu A, Kaibuchi K. Rho-associated kinase, a novel serine/threonine kinase, as a putative target for small GTP binding protein Rho. EMBO J 15: 2208-2216, 1996.
-
(1996)
EMBO J
, vol.15
, pp. 2208-2216
-
-
Matsui, T.1
Amano, M.2
Yamamoto, T.3
Chihara, K.4
Nakafuku, M.5
Ito, M.6
Nakano, T.7
Okawa, K.8
Iwamatsu, A.9
Kaibuchi, K.10
-
36
-
-
84893382560
-
Potential role of Rho kinase inhibitors in combating diabetes-related complications including diabetic neuropathy-a review
-
Mishra RK, Alokam R, Sriram D, Yogeeswari P. Potential role of Rho kinase inhibitors in combating diabetes-related complications including diabetic neuropathy-a review. Curr Diabetes Rev 29: 601-608, 2013.
-
(2013)
Curr Diabetes Rev
, vol.29
, pp. 601-608
-
-
Mishra, R.K.1
Alokam, R.2
Sriram, D.3
Yogeeswari, P.4
-
37
-
-
0030603119
-
ROCK-I and ROCK-II, two isoforms of Rho-associated coiled-coil forming protein serine/threonine kinase in mice
-
Nakagawa O, Fujisawa K, Ishizaki T, Saito Y, Nakao K, Narumiya S. ROCK-I and ROCK-II, two isoforms of Rho-associated coiled-coil forming protein serine/threonine kinase in mice. FEBS Lett 392: 189-193, 1996.
-
(1996)
FEBS Lett
, vol.392
, pp. 189-193
-
-
Nakagawa, O.1
Fujisawa, K.2
Ishizaki, T.3
Saito, Y.4
Nakao, K.5
Narumiya, S.6
-
38
-
-
34249719581
-
Adipogenesis in obesity requires close interplay between differentiating adipocytes, stromal cells, and blood vessels
-
Nishimura S, Manabe I, Nagasaki M, Hosoya Y, Yamashita H, Fujita H, Ohsugi M, Tobe K, Kadowaki T, Nagai R, Sugiura S. Adipogenesis in obesity requires close interplay between differentiating adipocytes, stromal cells, and blood vessels. Diabetes 56: 1517-1526, 2007.
-
(2007)
Diabetes
, vol.56
, pp. 1517-1526
-
-
Nishimura, S.1
Manabe, I.2
Nagasaki, M.3
Hosoya, Y.4
Yamashita, H.5
Fujita, H.6
Ohsugi, M.7
Tobe, K.8
Kadowaki, T.9
Nagai, R.10
Sugiura, S.11
-
39
-
-
35748976234
-
Genetic and pharmacological inhibition of Rhoassociated kinase II enhances adipogenesis
-
Noguchi M, Hosoda K, Fujikura J, Fujimoto M, Iwakura H, Tomita T, Ishii T, Arai N, Hirata M, Ebihara K, Masuzaki H, Itoh H, Narumiya S, Nakao K. Genetic and pharmacological inhibition of Rhoassociated kinase II enhances adipogenesis. J Biol Chem 282: 29574-29583, 2007.
-
(2007)
J Biol Chem
, vol.282
, pp. 29574-29583
-
-
Noguchi, M.1
Hosoda, K.2
Fujikura, J.3
Fujimoto, M.4
Iwakura, H.5
Tomita, T.6
Ishii, T.7
Arai, N.8
Hirata, M.9
Ebihara, K.10
Masuzaki, H.11
Itoh, H.12
Narumiya, S.13
Nakao, K.14
-
40
-
-
79151484704
-
Adipokines in inflammation and metabolic disease
-
Ouchi N, Parker JL, Lugus JJ, Walsh K. Adipokines in inflammation and metabolic disease. Nat Rev Immunol 11: 85-97, 2011.
-
(2011)
Nat Rev Immunol
, vol.11
, pp. 85-97
-
-
Ouchi, N.1
Parker, J.L.2
Lugus, J.J.3
Walsh, K.4
-
41
-
-
21244503503
-
Low salt intake modulates insulin signaling, JNK activity and IRS-1ser307 phosphorylation in rat tissues
-
Prada PO, Coelho MS, Zecchin HG, Dolnikoff MS, Gasparetti AL, Furukawa LN, Saad MJ, Heimann JC. Low salt intake modulates insulin signaling, JNK activity and IRS-1ser307 phosphorylation in rat tissues. J Endocrinol 185: 429-437, 2005.
-
(2005)
J Endocrinol
, vol.185
, pp. 429-437
-
-
Prada, P.O.1
Coelho, M.S.2
Zecchin, H.G.3
Dolnikoff, M.S.4
Gasparetti, A.L.5
Furukawa, L.N.6
Saad, M.J.7
Heimann, J.C.8
-
42
-
-
0038655599
-
RhoE binds to ROCK I and inhibits downstream signaling
-
Riento K, Guasch RM, Garg R, Jin B, Ridley AJ. RhoE binds to ROCK I and inhibits downstream signaling. Mol Cell Biol 23: 4219-4229, 2003.
-
(2003)
Mol Cell Biol
, vol.23
, pp. 4219-4229
-
-
Riento, K.1
Guasch, R.M.2
Garg, R.3
Jin, B.4
Ridley, A.J.5
-
43
-
-
84875994759
-
Distinct roles for ROCK1 and ROCK2 in the regulation of cell detachment
-
Shi J, Wu X, Surma M, Vemula S, Zhang L, Yang Y, Kapur R, Wei L. Distinct roles for ROCK1 and ROCK2 in the regulation of cell detachment. Cell Death Dis 4: e483, 2013.
-
(2013)
Cell Death Dis
, vol.4
-
-
Shi, J.1
Wu, X.2
Surma, M.3
Vemula, S.4
Zhang, L.5
Yang, Y.6
Kapur, R.7
Wei, L.8
-
44
-
-
67650539078
-
Thromboxane A2 receptor activates a Rho-associated kinase/LKB1/PTEN pathway to attenuate endothelium insulin signaling
-
Song P, Zhang M, Wang S, Xu J, Choi HC, Zou MH. Thromboxane A2 receptor activates a Rho-associated kinase/LKB1/PTEN pathway to attenuate endothelium insulin signaling. J Biol Chem 284: 17120-17128, 2009.
-
(2009)
J Biol Chem
, vol.284
, pp. 17120-17128
-
-
Song, P.1
Zhang, M.2
Wang, S.3
Xu, J.4
Choi, H.C.5
Zou, M.H.6
-
45
-
-
18444411005
-
Modulation of CREB activity by the Rho GTPase regulates cell and organism size during mouse embryonic development
-
Sordella R, Classon M, Hu KQ, Matheson SF, Brouns MR, Fine B, Zhang L, Takami H, Yamada Y, Settleman J. Modulation of CREB activity by the Rho GTPase regulates cell and organism size during mouse embryonic development. Dev Cell 2: 553-565, 2002.
-
(2002)
Dev Cell
, vol.2
, pp. 553-565
-
-
Sordella, R.1
Classon, M.2
Hu, K.Q.3
Matheson, S.F.4
Brouns, M.R.5
Fine, B.6
Zhang, L.7
Takami, H.8
Yamada, Y.9
Settleman, J.10
-
46
-
-
0346458780
-
Regulation of Cbl-associated protein/Cbl pathway in muscle and adipose tissues of two animal models of insulin resistance
-
Thirone AC, Carvalheira JB, Hirata AE, Velloso LA, Saad MJ. Regulation of Cbl-associated protein/Cbl pathway in muscle and adipose tissues of two animal models of insulin resistance. Endocrinology 145: 281-293, 2004.
-
(2004)
Endocrinology
, vol.145
, pp. 281-293
-
-
Thirone, A.C.1
Carvalheira, J.B.2
Hirata, A.E.3
Velloso, L.A.4
Saad, M.J.5
-
47
-
-
6344231714
-
Why three Rho proteins? RhoA, RhoB, RhoC, and cell motility
-
Wheeler AP, Ridley AJ. Why three Rho proteins? RhoA, RhoB, RhoC, and cell motility. Exp Cell Res 301: 43-49, 2004.
-
(2004)
Exp Cell Res
, vol.301
, pp. 43-49
-
-
Wheeler, A.P.1
Ridley, A.J.2
-
48
-
-
33947129737
-
Altered penile vascular reactivity and erection in the Zucker obese-diabetic rat
-
discussion 362-373
-
Wingard C, Fulton D, Husain S. Altered penile vascular reactivity and erection in the Zucker obese-diabetic rat. J Sex Med 4: 348-362; discussion 362-373, 2007.
-
(2007)
J Sex Med
, vol.4
, pp. 348-362
-
-
Wingard, C.1
Fulton, D.2
Husain, S.3
-
49
-
-
84874806070
-
Mechanisms of insulin resistance in obesity
-
Ye J. Mechanisms of insulin resistance in obesity. Front Med 7: 14-24, 2013.
-
(2013)
Front Med
, vol.7
, pp. 14-24
-
-
Ye, J.1
-
50
-
-
2642541849
-
Transgenic overexpression of protein-tyrosine phosphatase 1B in muscle causes insulin resistance, but overexpression with leukocyte antigen-related phosphatase does not additively impair insulin action
-
Zabolotny JM, Haj FG, Kim YB, Kim HJ, Shulman GI, Kim JK, Neel BG, Kahn BB. Transgenic overexpression of protein-tyrosine phosphatase 1B in muscle causes insulin resistance, but overexpression with leukocyte antigen-related phosphatase does not additively impair insulin action. J Biol Chem 279: 24844-24851, 2004.
-
(2004)
J Biol Chem
, vol.279
, pp. 24844-24851
-
-
Zabolotny, J.M.1
Haj, F.G.2
Kim, Y.B.3
Kim, H.J.4
Shulman, G.I.5
Kim, J.K.6
Neel, B.G.7
Kahn, B.B.8
-
51
-
-
33744473805
-
Targeted deletion of ROCK1 protects the heart against pressure overload by inhibiting reactive fibrosis
-
Zhang YM, Bo J, Taffet GE, Chang J, Shi J, Reddy AK, Michael LH, Schneider MD, Entman ML, Schwartz RJ, Wei L. Targeted deletion of ROCK1 protects the heart against pressure overload by inhibiting reactive fibrosis. FASEB J 20: 916-925, 2006.
-
(2006)
FASEB J
, vol.20
, pp. 916-925
-
-
Zhang, Y.M.1
Bo, J.2
Taffet, G.E.3
Chang, J.4
Shi, J.5
Reddy, A.K.6
Michael, L.H.7
Schneider, M.D.8
Entman, M.L.9
Schwartz, R.J.10
Wei, L.11
|