Rho-kinase regulates energy balance by targeting hypothalamic leptin receptor signaling

Nature Neuroscience

Volumn 15, Issue 10, 2012, Pages 1391-1398

  Huang, Hu ^a   Kong, Dong ^a   Byun, Kyung Hee ^b   Ye, Chianping ^a   Koda, Shuichi ^a   Lee, Dae Ho ^a   Oh, Byung Chul ^b   Lee, Sam W ^c   Lee, Bonghee ^b   Zabolotny, Janice M ^a   Kim, Min Seon ^d   Bjørbæk, Christian ^a   Lowell, Bradford B ^a   Kim, Young Bum ^a,b  

^a HARVARD MEDICAL SCHOOL   (United States)

^b Gachon University   (South Korea)

^c MASSACHUSETTS GENERAL HOSPITAL   (United States)

^d University of Ulsan College of Medicine   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

4 (1 AMINOETHYL) N (4 PYRIDYL)CYCLOHEXANECARBOXAMIDE; JANUS KINASE 2; LEPTIN; LEPTIN RECEPTOR; MESSENGER RNA; N BENZYL 2 CYANO 3 (3,4 DIHYDROXYPHENYL)ACRYLAMIDE; RHO KINASE; SMALL INTERFERING RNA; STAT3 PROTEIN; TRANSCRIPTION FACTOR FKHR;

ANIMAL EXPERIMENT; ARCUATE NUCLEUS; ARTICLE; BODY WEIGHT; BRAIN; CONTROLLED STUDY; ENERGY BALANCE; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; ENZYME REGULATION; FOOD INTAKE; HORMONAL REGULATION; HORMONE SENSITIVITY; HYPOTHALAMUS; MOUSE; NONHUMAN; OBESITY; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; SIGNAL TRANSDUCTION;

ACTION POTENTIALS; AGOUTI-RELATED PROTEIN; ANIMALS; APPETITE REGULATION; ARCUATE NUCLEUS; CELLS, CULTURED; EATING; ENERGY METABOLISM; HYPOTHALAMUS; JANUS KINASE 2; LEPTIN; MICE; MICE, INBRED C57BL; MICE, MUTANT STRAINS; MICE, TRANSGENIC; NEURONS; OBESITY; PHOSPHORYLATION; PRO-OPIOMELANOCORTIN; RECEPTORS, LEPTIN; RHO-ASSOCIATED KINASES; STAT3 TRANSCRIPTION FACTOR;

EID: 84866735424     PISSN: 10976256     EISSN: 15461726     Source Type: Journal    
DOI: 10.1038/nn.3207     Document Type: Article

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