Comparative analysis of RNAi screening technologies at genome-scale reveals an inherent processing inefficiency of the plasmid-based shrna hairpin

Combinatorial Chemistry and High Throughput Screening

Volumn 17, Issue 2, 2014, Pages 98-113

  Bhinder, Bhavneet ^a   Shum, David ^a   Djaballah, Hakim ^a  

^a MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

Author keywords

BDA method; Biogenesis; Comparative analysis; DROSHA; H score; HCS; Inefficient hairpin processing; MiRNA; OTE; Overlap; RNAi; Sequence walk through; ShRNA; SiRNA

Indexed keywords

MICRORNA; SHORT HAIRPIN RNA; SMALL INTERFERING RNA;

ARTICLE; BIOGENESIS; COMPARATIVE STUDY; GENE TECHNOLOGY; GENETIC TRANSFECTION; GENOME; HIGH THROUGHPUT SEQUENCING; NUCLEOTIDE SEQUENCE; OVERLAPPING GENE; PLASMID; PRIORITY JOURNAL; RNA INTERFERENCE;

BASE SEQUENCE; GENE LIBRARY; GENE REGULATORY NETWORKS; GENOMICS; HUMANS; MOLECULAR SEQUENCE DATA; PLASMIDS; RNA INTERFERENCE; RNA, SMALL INTERFERING;

EID: 84893328337     PISSN: 13862073     EISSN: 18755402     Source Type: Journal    
DOI: 10.2174/1386207317666140117101852     Document Type: Article

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