-
1
-
-
0030099527
-
Transporting therapeutics across the blood-brain barrier
-
doi: 10.1016/1357-4310(96)88720-X
-
Abbott, N. J., and Romero, I. A. (1996). Transporting therapeutics across the blood-brain barrier. Mol. Med. Today 2, 106-113. doi: 10.1016/1357-4310(96)88720-X
-
(1996)
Mol. Med. Today
, vol.2
, pp. 106-113
-
-
Abbott, N.J.1
Romero, I.A.2
-
2
-
-
0023869865
-
Perivascular iron deposition and other vascular damage in multiple sclerosis
-
doi: 10.1136/jnnp.51.2.260
-
Adams, C. W. (1988). Perivascular iron deposition and other vascular damage in multiple sclerosis. J. Neurol. Neurosurg. Psychiatry 51, 260-265. doi: 10.1136/jnnp.51.2.260
-
(1988)
J. Neurol. Neurosurg. Psychiatry
, vol.51
, pp. 260-265
-
-
Adams, C.W.1
-
3
-
-
53049105819
-
ALS drug development: Reflections from the past and a way forward
-
doi: 10.1016/j.nurt.2008.08.002
-
Aggarwal, S., and Cudkowicz, M. (2008). ALS drug development: reflections from the past and a way forward. Neurother. J. Am. Soc. Exp. Neurother. 5, 516-527. doi: 10.1016/j.nurt.2008.08.002
-
(2008)
Neurother. J. Am. Soc. Exp. Neurother.
, vol.5
, pp. 516-527
-
-
Aggarwal, S.1
Cudkowicz, M.2
-
4
-
-
0035833937
-
Immune reactivity in a mouse model of familial ALS correlates with disease progression
-
doi: 10.1212/WNL.57.7.1282
-
Alexianu, M. E., Kozovska, M., and Appel, S. H. (2001). Immune reactivity in a mouse model of familial ALS correlates with disease progression. Neurology 57, 1282-1289. doi: 10.1212/WNL.57.7.1282
-
(2001)
Neurology
, vol.57
, pp. 1282-1289
-
-
Alexianu, M.E.1
Kozovska, M.2
Appel, S.H.3
-
5
-
-
73849083781
-
In vivo morphological changes in animal models of amyotrophic lateral sclerosis and Alzheimer's-like disease: MRI approach
-
doi: 10.1002/ar.20995
-
Andjus, P. R., Bataveljić, D., Vanhoutte, G., Mitrecic, D., Pizzolante, F., Djogo, N., et al. (2009). In vivo morphological changes in animal models of amyotrophic lateral sclerosis and Alzheimer's-like disease: MRI approach. Anat. Rec. (Hoboken.) 292, 1882-1892. doi: 10.1002/ar.20995
-
(2009)
Anat. Rec. (Hoboken.)
, vol.292
, pp. 1882-1892
-
-
Andjus, P.R.1
Bataveljić, D.2
Vanhoutte, G.3
Mitrecic, D.4
Pizzolante, F.5
Djogo, N.6
-
6
-
-
0022271359
-
High levels of C3c in the cerebrospinal fluid from amyotrophic lateral sclerosis patients
-
doi: 10.1111/j.1600-0404.1985.tb01548.x
-
Annunziata, P., and Volpi, N. (1985). High levels of C3c in the cerebrospinal fluid from amyotrophic lateral sclerosis patients. Acta Neurol. Scand. 72, 61-64. doi: 10.1111/j.1600-0404.1985.tb01548.x
-
(1985)
Acta Neurol. Scand.
, vol.72
, pp. 61-64
-
-
Annunziata, P.1
Volpi, N.2
-
7
-
-
79958022133
-
The microglial-motoneuron dialogue in ALS
-
Appel, S. H., Zhao, W., Beers, D. R., and Henkel, J. S. (2011). The microglial-motoneuron dialogue in ALS. Acta Myol. 30, 4-8.
-
(2011)
Acta Myol.
, vol.30
, pp. 4-8
-
-
Appel, S.H.1
Zhao, W.2
Beers, D.R.3
Henkel, J.S.4
-
8
-
-
78649467527
-
Pericytes regulate the blood-brain barrier
-
doi: 10.1038/nature09522
-
Armulik, A., Genové, G., Mäe, M., Nisancioglu, M. H., Wallgard, E., Niaudet, C., et al. (2010). Pericytes regulate the blood-brain barrier. Nature 468, 557-561. doi: 10.1038/nature09522
-
(2010)
Nature
, vol.468
, pp. 557-561
-
-
Armulik, A.1
Genové, G.2
Mäe, M.3
Nisancioglu, M.H.4
Wallgard, E.5
Niaudet, C.6
-
9
-
-
0032530520
-
Role of the CNS microvascular pericyte in the blood-brain barrier
-
doi: 10.1002/(SICI)1097-4547(19980915)53:6<637::AID-JNR1>3.0.CO;2-6
-
Balabanov, R., and Dore-Duffy, P. (1998). Role of the CNS microvascular pericyte in the blood-brain barrier. J. Neurosci. Res. 53, 637-644. doi: 10.1002/(SICI)1097-4547(19980915)53:6<637::AID-JNR1>3.0.CO;2-6
-
(1998)
J. Neurosci. Res.
, vol.53
, pp. 637-644
-
-
Balabanov, R.1
Dore-Duffy, P.2
-
10
-
-
2342471420
-
The blood-brain barrier: An overview: Structure, regulation, and clinical implications
-
doi: 10.1016/j.nbd.2003.12.016
-
Ballabh, P., Braun, A., and Nedergaard, M. (2004). The blood-brain barrier: an overview: structure, regulation, and clinical implications. Neurobiol. Dis. 16, 1-13. doi: 10.1016/j.nbd.2003.12.016
-
(2004)
Neurobiol. Dis.
, vol.16
, pp. 1-13
-
-
Ballabh, P.1
Braun, A.2
Nedergaard, M.3
-
11
-
-
80051551970
-
The blood-spinal cord barrier: Morphology and clinical implications
-
doi: 10.1002/ana.22421
-
Bartanusz, V., Jezova, D., Alajajian, B., and Digicaylioglu, M. (2011). The blood-spinal cord barrier: morphology and clinical implications. Ann. Neurol. 70, 194-206. doi: 10.1002/ana.22421
-
(2011)
Ann. Neurol.
, vol.70
, pp. 194-206
-
-
Bartanusz, V.1
Jezova, D.2
Alajajian, B.3
Digicaylioglu, M.4
-
12
-
-
84867631997
-
Changes in the astrocytic aquaporin-4 and inwardly rectifying potassium channel expression in the brain of the amyotrophic lateral sclerosis SOD1(G93A) rat model
-
doi: 10.1002/glia.22414
-
Bataveljić, D., Nikolić, L., Milosević, M., Todorović, N., and Andjus, P. R. (2012). Changes in the astrocytic aquaporin-4 and inwardly rectifying potassium channel expression in the brain of the amyotrophic lateral sclerosis SOD1(G93A) rat model. Glia 60, 1991-2003. doi: 10.1002/glia.22414
-
(2012)
Glia
, vol.60
, pp. 1991-2003
-
-
Bataveljić, D.1
Nikolić, L.2
Milosević, M.3
Todorović, N.4
Andjus, P.R.5
-
13
-
-
1642454475
-
ABC transporters and the blood-brain barrier
-
doi: 10.2174/1381612043384844
-
Begley, D. J. (2004). ABC transporters and the blood-brain barrier. Curr. Pharm. Des. 10, 1295-1312. doi: 10.2174/1381612043384844
-
(2004)
Curr. Pharm. Des.
, vol.10
, pp. 1295-1312
-
-
Begley, D.J.1
-
14
-
-
0141620181
-
Structural and functional aspects of the blood-brain barrier
-
Begley, D. J., and Brightman, M. W. (2003). Structural and functional aspects of the blood-brain barrier. Prog. Drug Res. 61, 39-78.
-
(2003)
Prog. Drug Res.
, vol.61
, pp. 39-78
-
-
Begley, D.J.1
Brightman, M.W.2
-
15
-
-
80052330506
-
Amyloid triggers extensive cerebral angiogenesis causing blood brain barrier permeability and hypervascularity in Alzheimer's disease
-
doi: 10.1371/journal.pone.0023789
-
Biron, K. E., Dickstein, D. L., Gopaul, R., and Jefferies, W. A. (2011). Amyloid triggers extensive cerebral angiogenesis causing blood brain barrier permeability and hypervascularity in Alzheimer's disease. PLoS ONE 6:e23789. doi: 10.1371/journal.pone.0023789
-
(2011)
PLoS ONE
, vol.6
-
-
Biron, K.E.1
Dickstein, D.L.2
Gopaul, R.3
Jefferies, W.A.4
-
16
-
-
13844255218
-
Circulating endothelial cells. Biomarker of vascular disease
-
doi:10.1267/THRO05020228
-
Blann, A. D., Woywodt, A., Bertolini, F., Bull, T. M., Buyon, J. P., Clancy, R. M., et al. (2005). Circulating endothelial cells. Biomarker of vascular disease. Thromb. Haemost. 93, 228-235. doi:10.1267/THRO05020228
-
(2005)
Thromb. Haemost.
, vol.93
, pp. 228-235
-
-
Blann, A.D.1
Woywodt, A.2
Bertolini, F.3
Bull, T.M.4
Buyon, J.P.5
Clancy, R.M.6
-
17
-
-
33744798774
-
Onset and progression in inherited ALS determined by motor neurons and microglia
-
doi: 10.1126/science.1123511
-
Boillée, S., Yamanaka, K., Lobsiger, C. S., Copeland, N. G., Jenkins, N. A., Kassiotis, G., et al. (2006). Onset and progression in inherited ALS determined by motor neurons and microglia. Science 312, 1389-1392. doi: 10.1126/science.1123511
-
(2006)
Science
, vol.312
, pp. 1389-1392
-
-
Boillée, S.1
Yamanaka, K.2
Lobsiger, C.S.3
Copeland, N.G.4
Jenkins, N.A.5
Kassiotis, G.6
-
18
-
-
77954563517
-
Metalloproteinase alterations in the bone marrow of ALS patients
-
doi: 10.1007/s00109-009-0584-7
-
Bossolasco, P., Cova, L., Calzarossa, C., Servida, F., Mencacci, N. E., Onida, F., et al. (2010). Metalloproteinase alterations in the bone marrow of ALS patients. J. Mol. Med. (Berl.) 88, 553-564. doi: 10.1007/s00109-009-0584-7
-
(2010)
J. Mol. Med. (Berl.)
, vol.88
, pp. 553-564
-
-
Bossolasco, P.1
Cova, L.2
Calzarossa, C.3
Servida, F.4
Mencacci, N.E.5
Onida, F.6
-
19
-
-
0022253324
-
The blood-brain barrier. Transport across the cerebral endothelium
-
doi: 10.1161/01.RES.57.2.213
-
Bradbury, M. W. (1985). The blood-brain barrier. Transport across the cerebral endothelium. Circ. Res. 57, 213-222. doi: 10.1161/01.RES.57.2.213
-
(1985)
Circ. Res.
, vol.57
, pp. 213-222
-
-
Bradbury, M.W.1
-
20
-
-
3943102116
-
Unraveling the mechanisms involved in motor neuron degeneration in ALS
-
doi: 10.1146/annurev.neuro.27.070203.144244
-
Bruijn, L. I., Miller, T. M., and Cleveland, D. W. (2004). Unraveling the mechanisms involved in motor neuron degeneration in ALS. Annu. Rev. Neurosci. 27, 723-749. doi: 10.1146/annurev.neuro.27.070203.144244
-
(2004)
Annu. Rev. Neurosci.
, vol.27
, pp. 723-749
-
-
Bruijn, L.I.1
Miller, T.M.2
Cleveland, D.W.3
-
21
-
-
50849131655
-
Trans-cellular migration: Cell-cell contacts get intimate
-
doi: 10.1016/j.ceb.2008.05.007
-
Carman, C. V., and Springer, T. A. (2008). Trans-cellular migration: cell-cell contacts get intimate. Curr. Opin. Cell Biol. 20, 533-540. doi: 10.1016/j.ceb.2008.05.007
-
(2008)
Curr. Opin. Cell Biol.
, vol.20
, pp. 533-540
-
-
Carman, C.V.1
Springer, T.A.2
-
22
-
-
32644447098
-
Increased circulating endothelial cells in acute heart failure: Comparison with von Willebrand factor and soluble E-selectin
-
doi: 10.1016/j.ejheart.2005.06.010
-
Chong, A. Y., Lip, G. Y. H., Freestone, B., and Blann, A. D. (2006). Increased circulating endothelial cells in acute heart failure: comparison with von Willebrand factor and soluble E-selectin. Eur. J. Heart Fail. 8, 167-172. doi: 10.1016/j.ejheart.2005.06.010
-
(2006)
Eur. J. Heart Fail.
, vol.8
, pp. 167-172
-
-
Chong, A.Y.1
Lip, G.Y.H.2
Freestone, B.3
Blann, A.D.4
-
23
-
-
0029655250
-
Ultrastructural features of the blood-brain barrier in biopsy tissue from Alzheimer's disease patients
-
doi: 10.1007/s004010050386
-
Claudio, L. (1996). Ultrastructural features of the blood-brain barrier in biopsy tissue from Alzheimer's disease patients. Acta Neuropathol. (Berl.) 91, 6-14. doi: 10.1007/s004010050386
-
(1996)
Acta Neuropathol. (Berl.)
, vol.91
, pp. 6-14
-
-
Claudio, L.1
-
24
-
-
0035516124
-
From Charcot to Lou Gehrig: Deciphering selective motor neuron death in ALS
-
doi: 10.1038/35097565
-
Cleveland, D. W., and Rothstein, J. D. (2001). From Charcot to Lou Gehrig: deciphering selective motor neuron death in ALS. Nat. Rev. Neurosci. 2, 806-819. doi: 10.1038/35097565
-
(2001)
Nat. Rev. Neurosci.
, vol.2
, pp. 806-819
-
-
Cleveland, D.W.1
Rothstein, J.D.2
-
25
-
-
1842714301
-
Neuroinflammation, COX-2, and ALS-a dual role?
-
doi: 10.1016/j.expneurol.2003.12.009
-
Consilvio, C., Vincent, A. M., and Feldman, E. L. (2004). Neuroinflammation, COX-2, and ALS-a dual role? Exp. Neurol. 187, 1-10. doi: 10.1016/j.expneurol.2003.12.009
-
(2004)
Exp. Neurol.
, vol.187
, pp. 1-10
-
-
Consilvio, C.1
Vincent, A.M.2
Feldman, E.L.3
-
26
-
-
10744222650
-
A randomized, placebo-controlled trial of topiramate in amyotrophic lateral sclerosis
-
doi: 10.1212/WNL.61.4.456
-
Cudkowicz, M. E., Shefner, J. M., Schoenfeld, D. A., Brown, R. H. Jr., Johnson, H., Qureshi, M., et al. (2003). A randomized, placebo-controlled trial of topiramate in amyotrophic lateral sclerosis. Neurology 61, 456-464. doi: 10.1212/WNL.61.4.456
-
(2003)
Neurology
, vol.61
, pp. 456-464
-
-
Cudkowicz, M.E.1
Shefner, J.M.2
Schoenfeld, D.A.3
Brown Jr., R.H.4
Johnson, H.5
Qureshi, M.6
-
27
-
-
79957934229
-
Brain microvascular pericytes in health and disease
-
doi: 10.1007/s00401-011-0847-6
-
Dalkara, T., Gursoy-Ozdemir, Y., and Yemisci, M. (2011). Brain microvascular pericytes in health and disease. Acta Neuropathol. (Berl.) 122, 1-9. doi: 10.1007/s00401-011-0847-6
-
(2011)
Acta Neuropathol. (Berl.)
, vol.122
, pp. 1-9
-
-
Dalkara, T.1
Gursoy-Ozdemir, Y.2
Yemisci, M.3
-
28
-
-
0026096003
-
Molecular anatomy of the blood-brain barrier as defined by immunocytochemistry
-
Dermietzel, R., and Krause, D. (1991). Molecular anatomy of the blood-brain barrier as defined by immunocytochemistry. Int. Rev. Cytol. 127, 57-109.
-
(1991)
Int. Rev. Cytol.
, vol.127
, pp. 57-109
-
-
Dermietzel, R.1
Krause, D.2
-
29
-
-
84857624257
-
Evidence for angiogenesis in Parkinson's disease, incidental Lewy body disease, and progressive supranuclear palsy
-
doi: 10.1007/s00702-011-0684-8
-
Desai Bradaric, B., Patel, A., Schneider, J. A., Carvey, P. M., and Hendey, B. (2012). Evidence for angiogenesis in Parkinson's disease, incidental Lewy body disease, and progressive supranuclear palsy. J. Neural Transm. 119, 59-71. doi: 10.1007/s00702-011-0684-8
-
(2012)
J. Neural Transm.
, vol.119
, pp. 59-71
-
-
Desai Bradaric, B.1
Patel, A.2
Schneider, J.A.3
Carvey, P.M.4
Hendey, B.5
-
30
-
-
67349132699
-
Evidence of angiogenic vessels in Alzheimer's disease
-
doi: 10.1007/s00702-009-0226-9
-
Desai, B. S., Schneider, J. A., Li, J.-L., Carvey, P. M., and Hendey, B. (2009). Evidence of angiogenic vessels in Alzheimer's disease. J. Neural Transm. 116, 587-597. doi: 10.1007/s00702-009-0226-9
-
(2009)
J. Neural Transm.
, vol.116
, pp. 587-597
-
-
Desai, B.S.1
Schneider, J.A.2
Li, J.-L.3
Carvey, P.M.4
Hendey, B.5
-
31
-
-
0030791228
-
The blood-brain barrier in neuroinflammatory diseases
-
de Vries, H. E., Kuiper, J., de Boer, A. G., Van Berkel, T. J., and Breimer, D. D. (1997). The blood-brain barrier in neuroinflammatory diseases. Pharmacol. Rev. 49, 143-155.
-
(1997)
Pharmacol. Rev.
, vol.49
, pp. 143-155
-
-
de Vries, H.E.1
Kuiper, J.2
de Boer, A.G.3
Van Berkel, T.J.4
Breimer, D.D.5
-
32
-
-
0021287843
-
Deposits of IgG and C3 in the spinal cord and motor cortex of ALS patients
-
doi: 10.1016/0165-5728(84)90042-0
-
Donnenfeld, H., Kascsak, R. J., and Bartfeld, H. (1984). Deposits of IgG and C3 in the spinal cord and motor cortex of ALS patients. J. Neuroimmunol. 6, 51-57. doi: 10.1016/0165-5728(84)90042-0
-
(1984)
J. Neuroimmunol.
, vol.6
, pp. 51-57
-
-
Donnenfeld, H.1
Kascsak, R.J.2
Bartfeld, H.3
-
33
-
-
0035500386
-
Cytokine upregulation in a murine model of familial amyotrophic lateral sclerosis
-
doi: 10.1016/S0169-328X(01)00242-X
-
Elliott, J. L. (2001). Cytokine upregulation in a murine model of familial amyotrophic lateral sclerosis. Brain Res. Mol. Brain Res. 95, 172-178. doi: 10.1016/S0169-328X(01)00242-X
-
(2001)
Brain Res. Mol. Brain Res.
, vol.95
, pp. 172-178
-
-
Elliott, J.L.1
-
34
-
-
48949117580
-
The blood-central nervous system barriers actively control immune cell entry into the central nervous system
-
doi: 10.2174/138161208784705432
-
Engelhardt, B. (2008). The blood-central nervous system barriers actively control immune cell entry into the central nervous system. Curr. Pharm. Des. 14, 1555-1565. doi: 10.2174/138161208784705432
-
(2008)
Curr. Pharm. Des.
, vol.14
, pp. 1555-1565
-
-
Engelhardt, B.1
-
35
-
-
0024994099
-
IgG reactivity in the spinal cord and motor cortex in amyotrophic lateral sclerosis
-
doi: 10.1001/archneur.1990.00530110068019
-
Engelhardt, J. I., and Appel, S. H. (1990). IgG reactivity in the spinal cord and motor cortex in amyotrophic lateral sclerosis. Arch. Neurol. 47, 1210-1216. doi: 10.1001/archneur.1990.00530110068019
-
(1990)
Arch. Neurol.
, vol.47
, pp. 1210-1216
-
-
Engelhardt, J.I.1
Appel, S.H.2
-
36
-
-
0029007095
-
Antibodies to calcium channels from ALS patients passively transferred to mice selectively increase intracellular calcium and induce ultrastructural changes in motoneurons
-
doi: 10.1002/syn.890200302
-
Engelhardt, J. I., Siklós, L., Kömüves, L., Smith, R. G., and Appel, S. H. (1995). Antibodies to calcium channels from ALS patients passively transferred to mice selectively increase intracellular calcium and induce ultrastructural changes in motoneurons. Synapse 20, 185-199. doi: 10.1002/syn.890200302
-
(1995)
Synapse
, vol.20
, pp. 185-199
-
-
Engelhardt, J.I.1
Siklós, L.2
Kömüves, L.3
Smith, R.G.4
Appel, S.H.5
-
37
-
-
0027473452
-
Lymphocytic infiltrates in the spinal cord in amyotrophic lateral sclerosis
-
doi: 10.1001/archneur.1993.00540010026013
-
Engelhardt, J. I., Tajti, J., and Appel, S. H. (1993). Lymphocytic infiltrates in the spinal cord in amyotrophic lateral sclerosis. Arch. Neurol. 50, 30-36. doi: 10.1001/archneur.1993.00540010026013
-
(1993)
Arch. Neurol.
, vol.50
, pp. 30-36
-
-
Engelhardt, J.I.1
Tajti, J.2
Appel, S.H.3
-
38
-
-
84873278957
-
Inflammation and neurovascular changes in amyotrophic lateral sclerosis
-
doi: 10.1016/j.mcn.2012.10.008
-
Evans, M. C., Couch, Y., Sibson, N., and Turner, M. R. (2013). Inflammation and neurovascular changes in amyotrophic lateral sclerosis. Mol. Cell. Neurosci. 53, 34-41. doi: 10.1016/j.mcn.2012.10.008
-
(2013)
Mol. Cell. Neurosci.
, vol.53
, pp. 34-41
-
-
Evans, M.C.1
Couch, Y.2
Sibson, N.3
Turner, M.R.4
-
39
-
-
70449529637
-
Approaches to transport therapeutic drugs across the blood-brain barrier to treat brain diseases
-
doi: 10.1016/j.nbd.2009.07.028
-
Gabathuler, R. (2010). Approaches to transport therapeutic drugs across the blood-brain barrier to treat brain diseases. Neurobiol. Dis. 37, 48-57. doi: 10.1016/j.nbd.2009.07.028
-
(2010)
Neurobiol. Dis.
, vol.37
, pp. 48-57
-
-
Gabathuler, R.1
-
40
-
-
34250658083
-
Ultrastructure of blood-brain barrier and blood-spinal cord barrier in SOD1 mice modeling ALS
-
doi: 10.1016/j.brainres.2007.04.044
-
Garbuzova-Davis, S., Haller, E., Saporta, S., Kolomey, I., Nicosia, S. V., and Sanberg, P. R. (2007a). Ultrastructure of blood-brain barrier and blood-spinal cord barrier in SOD1 mice modeling ALS. Brain Res. 1157, 126-137. doi: 10.1016/j.brainres.2007.04.044
-
(2007)
Brain Res.
, vol.1157
, pp. 126-137
-
-
Garbuzova-Davis, S.1
Haller, E.2
Saporta, S.3
Kolomey, I.4
Nicosia, S.V.5
Sanberg, P.R.6
-
41
-
-
49849094080
-
Evidence of compromised blood-spinal cord barrier in early and late symptomatic SOD1 mice modeling ALS
-
doi: 10.1371/journal.pone.0001205
-
Garbuzova-Davis, S., Saporta, S., Haller, E., Kolomey, I., Bennett, S. P., Potter, H., et al. (2007b). Evidence of compromised blood-spinal cord barrier in early and late symptomatic SOD1 mice modeling ALS. PLoS ONE 2:e1205. doi: 10.1371/journal.pone.0001205
-
(2007)
PLoS ONE
, vol.2
-
-
Garbuzova-Davis, S.1
Saporta, S.2
Haller, E.3
Kolomey, I.4
Bennett, S.P.5
Potter, H.6
-
42
-
-
84864775702
-
Impaired blood-brain/spinal cord barrier in ALS patients
-
doi: 10.1016/j.brainres.2012.05.056
-
Garbuzova-Davis, S., Hernandez-Ontiveros, D. G., Rodrigues, M. C. O., Haller, E., Frisina-Deyo, A., Mirtyl, S., et al. (2012). Impaired blood-brain/spinal cord barrier in ALS patients. Brain Res. 1469, 114-128. doi: 10.1016/j.brainres.2012.05.056
-
(2012)
Brain Res.
, vol.1469
, pp. 114-128
-
-
Garbuzova-Davis, S.1
Hernandez-Ontiveros, D.G.2
Rodrigues, M.C.O.3
Haller, E.4
Frisina-Deyo, A.5
Mirtyl, S.6
-
43
-
-
79958850046
-
Amyotrophic lateral sclerosis: A neurovascular disease
-
doi: 10.1016/j.brainres.2011.04.049
-
Garbuzova-Davis, S., Rodrigues, M. C. O., Hernandez-Ontiveros, D. G., Louis, M. K., Willing, A. E., Borlongan, C. V., et al. (2011). Amyotrophic lateral sclerosis: a neurovascular disease. Brain Res. 1398, 113-125. doi: 10.1016/j.brainres.2011.04.049
-
(2011)
Brain Res.
, vol.1398
, pp. 113-125
-
-
Garbuzova-Davis, S.1
Rodrigues, M.C.O.2
Hernandez-Ontiveros, D.G.3
Louis, M.K.4
Willing, A.E.5
Borlongan, C.V.6
-
44
-
-
54049123282
-
Implications of blood-brain barrier disruption in ALS
-
doi: 10.1080/17482960802160990
-
Garbuzova-Davis, S., Saporta, S., and Sanberg, P. R. (2008). Implications of blood-brain barrier disruption in ALS. Amyotroph. Lateral Scler. 9, 375-376. doi: 10.1080/17482960802160990
-
(2008)
Amyotroph. Lateral Scler.
, vol.9
, pp. 375-376
-
-
Garbuzova-Davis, S.1
Saporta, S.2
Sanberg, P.R.3
-
45
-
-
77956526511
-
Reduction of circulating endothelial cells in peripheral blood of ALS patients
-
doi: 10.1371/journal.pone.0010614
-
Garbuzova-Davis, S., Woods, R. L., Louis, M. K., Zesiewicz, T. A., Kuzmin-Nichols, N., Sullivan, K. L., et al. (2010). Reduction of circulating endothelial cells in peripheral blood of ALS patients. PLoS ONE 5:e10614. doi: 10.1371/journal.pone.0010614
-
(2010)
PLoS ONE
, vol.5
-
-
Garbuzova-Davis, S.1
Woods, R.L.2
Louis, M.K.3
Zesiewicz, T.A.4
Kuzmin-Nichols, N.5
Sullivan, K.L.6
-
46
-
-
36148960127
-
Efficacy of minocycline in patients with amyotrophic lateral sclerosis: A phase III randomised trial
-
doi: 10.1016/S1474-4422(07)70270-3
-
Gordon, P. H., Moore, D. H., Miller, R. G., Florence, J. M., Verheijde, J. L., Doorish, C., et al. (2007). Efficacy of minocycline in patients with amyotrophic lateral sclerosis: a phase III randomised trial. Lancet Neurol. 6, 1045-1053. doi: 10.1016/S1474-4422(07)70270-3
-
(2007)
Lancet Neurol.
, vol.6
, pp. 1045-1053
-
-
Gordon, P.H.1
Moore, D.H.2
Miller, R.G.3
Florence, J.M.4
Verheijde, J.L.5
Doorish, C.6
-
47
-
-
80053458900
-
Cerebral microvascular endothelium and the pathogenesis of neurodegenerative diseases
-
doi: 10.1017/S1462399411001918
-
Grammas, P., Martinez, J., and Miller, B. (2011). Cerebral microvascular endothelium and the pathogenesis of neurodegenerative diseases. Expert Rev. Mol. Med. 13, e19. doi: 10.1017/S1462399411001918
-
(2011)
Expert Rev. Mol. Med.
, vol.13
-
-
Grammas, P.1
Martinez, J.2
Miller, B.3
-
48
-
-
0037379650
-
A randomized sequential trial of creatine in amyotrophic lateral sclerosis
-
doi: 10.1002/ana.10554
-
Groeneveld, G. J., Veldink, J. H., van der Tweel, I., Kalmijn, S., Beijer, C., de Visser, M., et al. (2003). A randomized sequential trial of creatine in amyotrophic lateral sclerosis. Ann. Neurol. 53, 437-445. doi: 10.1002/ana.10554
-
(2003)
Ann. Neurol.
, vol.53
, pp. 437-445
-
-
Groeneveld, G.J.1
Veldink, J.H.2
van der Tweel, I.3
Kalmijn, S.4
Beijer, C.5
de Visser, M.6
-
49
-
-
80052783545
-
Astrocytes from familial and sporadic ALS patients are toxic to motor neurons
-
doi: 10.1038/nbt.1957
-
Haidet-Phillips, A. M., Hester, M. E., Miranda, C. J., Meyer, K., Braun, L., Frakes, A., et al. (2011). Astrocytes from familial and sporadic ALS patients are toxic to motor neurons. Nat. Biotechnol. 29, 824-828. doi: 10.1038/nbt.1957
-
(2011)
Nat. Biotechnol.
, vol.29
, pp. 824-828
-
-
Haidet-Phillips, A.M.1
Hester, M.E.2
Miranda, C.J.3
Meyer, K.4
Braun, L.5
Frakes, A.6
-
50
-
-
0032125587
-
Relationship of microglial and astrocytic activation to disease onset and progression in a transgenic model of familial ALS
-
doi: 10.1002/(SICI)1098-1136(199807)23:3<249::AID-GLIA7>3.0.CO;2-#
-
Hall, E. D., Oostveen, J. A., and Gurney, M. E. (1998). Relationship of microglial and astrocytic activation to disease onset and progression in a transgenic model of familial ALS. Glia 23, 249-256. doi: 10.1002/(SICI)1098-1136(199807)23:3<249::AID-GLIA7>3.0.CO;2-#
-
(1998)
Glia
, vol.23
, pp. 249-256
-
-
Hall, E.D.1
Oostveen, J.A.2
Gurney, M.E.3
-
51
-
-
67649391341
-
Decreased mRNA expression of tight junction proteins in lumbar spinal cords of patients with ALS
-
doi: 10.1212/WNL.0b013e3181a41228
-
Henkel, J. S., Beers, D. R., Wen, S., Bowser, R., and Appel, S. H. (2009). Decreased mRNA expression of tight junction proteins in lumbar spinal cords of patients with ALS. Neurology 72, 1614-1616. doi: 10.1212/WNL.0b013e3181a41228
-
(2009)
Neurology
, vol.72
, pp. 1614-1616
-
-
Henkel, J.S.1
Beers, D.R.2
Wen, S.3
Bowser, R.4
Appel, S.H.5
-
52
-
-
10744229158
-
Presence of dendritic cells, MCP-1, and activated microglia/macrophages in amyotrophic lateral sclerosis spinal cord tissue
-
doi: 10.1002/ana.10805
-
Henkel, J. S., Engelhardt, J. I., Siklós, L., Simpson, E. P., Kim, S. H., Pan, T., et al. (2004). Presence of dendritic cells, MCP-1, and activated microglia/macrophages in amyotrophic lateral sclerosis spinal cord tissue. Ann. Neurol. 55, 221-235. doi: 10.1002/ana.10805
-
(2004)
Ann. Neurol.
, vol.55
, pp. 221-235
-
-
Henkel, J.S.1
Engelhardt, J.I.2
Siklós, L.3
Simpson, E.P.4
Kim, S.H.5
Pan, T.6
-
53
-
-
0030270961
-
Pericytes in the microvasculature
-
Hirschi, K. K., and D'Amore, P. A. (1996). Pericytes in the microvasculature. Cardiovasc. Res. 32, 687-698.
-
(1996)
Cardiovasc. Res.
, vol.32
, pp. 687-698
-
-
Hirschi, K.K.1
D'Amore, P.A.2
-
54
-
-
84885424462
-
Immune system alterations in amyotrophic lateral sclerosis
-
doi: 10.1111/ane.12125 [Epub ahead of print]
-
Hovden, H., Frederiksen, J. L., and Pedersen, S. W. (2013). Immune system alterations in amyotrophic lateral sclerosis. Acta Neurol. Scand. doi: 10.1111/ane.12125 [Epub ahead of print].
-
(2013)
Acta Neurol. Scand.
-
-
Hovden, H.1
Frederiksen, J.L.2
Pedersen, S.W.3
-
55
-
-
13444300993
-
Circulating endothelial (progenitor) cells reflect the state of the endothelium: Vascular injury, repair and neovascularization
-
doi: 10.1111/j.1423-0410.2005.00589.x
-
Hunting, C. B., Noort, W. A., and Zwaginga, J. J. (2005). Circulating endothelial (progenitor) cells reflect the state of the endothelium: vascular injury, repair and neovascularization. Vox Sang. 88, 1-9. doi: 10.1111/j.1423-0410.2005.00589.x
-
(2005)
Vox Sang.
, vol.88
, pp. 1-9
-
-
Hunting, C.B.1
Noort, W.A.2
Zwaginga, J.J.3
-
56
-
-
84861683789
-
Selective increase of two ABC drug efflux transporters at the blood-spinal cord barrier suggests induced pharmacoresistance in ALS
-
doi: 10.1016/j.nbd.2012.03.040
-
Jablonski, M. R., Jacob, D. A., Campos, C., Miller, D. S., Maragakis, N. J., Pasinelli, P., et al. (2012). Selective increase of two ABC drug efflux transporters at the blood-spinal cord barrier suggests induced pharmacoresistance in ALS. Neurobiol. Dis. 47, 194-200. doi: 10.1016/j.nbd.2012.03.040
-
(2012)
Neurobiol. Dis.
, vol.47
, pp. 194-200
-
-
Jablonski, M.R.1
Jacob, D.A.2
Campos, C.3
Miller, D.S.4
Maragakis, N.J.5
Pasinelli, P.6
-
57
-
-
84856214019
-
The functional deficiency of bone marrow mesenchymal stromal cells in ALS patients is proportional to disease progression rate
-
doi: 10.1016/j.expneurol.2011.11.021
-
Koh, S.-H., Baik, W., Noh, M. Y., Cho, G. W., Kim, H. Y., Kim, K. S., et al. (2012). The functional deficiency of bone marrow mesenchymal stromal cells in ALS patients is proportional to disease progression rate. Exp. Neurol. 233, 472-480. doi: 10.1016/j.expneurol.2011.11.021
-
(2012)
Exp. Neurol.
, vol.233
, pp. 472-480
-
-
Koh, S.-H.1
Baik, W.2
Noh, M.Y.3
Cho, G.W.4
Kim, H.Y.5
Kim, K.S.6
-
58
-
-
64049085365
-
The pericyte: Cellular regulator of microvascular blood flow
-
doi: 10.1016/j.mvr.2009.01.007
-
Kutcher, M. E., and Herman, I. M. (2009). The pericyte: cellular regulator of microvascular blood flow. Microvasc. Res. 77, 235-246. doi: 10.1016/j.mvr.2009.01.007
-
(2009)
Microvasc. Res.
, vol.77
, pp. 235-246
-
-
Kutcher, M.E.1
Herman, I.M.2
-
59
-
-
0021247422
-
Cerebrospinal fluid (CSF) findings in amyotrophic lateral sclerosis
-
doi: 10.1007/BF00313720
-
Leonardi, A., Abbruzzese, G., Arata, L., Cocito, L., and Vische, M. (1984). Cerebrospinal fluid (CSF) findings in amyotrophic lateral sclerosis. J. Neurol. 231, 75-78. doi: 10.1007/BF00313720
-
(1984)
J. Neurol.
, vol.231
, pp. 75-78
-
-
Leonardi, A.1
Abbruzzese, G.2
Arata, L.3
Cocito, L.4
Vische, M.5
-
60
-
-
34548230927
-
Getting to the site of inflammation: The leukocyte adhesion cascade updated
-
doi: 10.1038/nri2156
-
Ley, K., Laudanna, C., Cybulsky, M. I., and Nourshargh, S. (2007). Getting to the site of inflammation: the leukocyte adhesion cascade updated. Nat. Rev. Immunol. 7, 678-689. doi: 10.1038/nri2156
-
(2007)
Nat. Rev. Immunol.
, vol.7
, pp. 678-689
-
-
Ley, K.1
Laudanna, C.2
Cybulsky, M.I.3
Nourshargh, S.4
-
61
-
-
0036148894
-
Induction of type IV collagen and other basement-membrane-associated proteins after spinal cord injury of the adult rat may participate in formation of the glial scar
-
doi: 10.1006/exnr.2001.7800
-
Liesi, P., and Kauppila, T. (2002). Induction of type IV collagen and other basement-membrane-associated proteins after spinal cord injury of the adult rat may participate in formation of the glial scar. Exp. Neurol. 173, 31-45. doi: 10.1006/exnr.2001.7800
-
(2002)
Exp. Neurol.
, vol.173
, pp. 31-45
-
-
Liesi, P.1
Kauppila, T.2
-
62
-
-
77950517721
-
Mast cells as early responders in the regulation of acute blood-brain barrier changes after cerebral ischemia and hemorrhage
-
doi: 10.1038/jcbfm.2009.282
-
Lindsberg, P. J., Strbian, D., and Karjalainen-Lindsberg, M.-L. (2010). Mast cells as early responders in the regulation of acute blood-brain barrier changes after cerebral ischemia and hemorrhage. J. Cereb. Blood Flow Metab. 30, 689-702. doi: 10.1038/jcbfm.2009.282
-
(2010)
J. Cereb. Blood Flow Metab.
, vol.30
, pp. 689-702
-
-
Lindsberg, P.J.1
Strbian, D.2
Karjalainen-Lindsberg, M.-L.3
-
63
-
-
0026725537
-
Cytokine regulation of endothelial cell function
-
Mantovani, A., Bussolino, F., and Dejana, E. (1992). Cytokine regulation of endothelial cell function. Faseb J. 6, 2591-2599.
-
(1992)
Faseb J.
, vol.6
, pp. 2591-2599
-
-
Mantovani, A.1
Bussolino, F.2
Dejana, E.3
-
64
-
-
17344363713
-
Cell biology of the neurovascular unit: Implications for drug delivery across the blood-brain barrier
-
doi: 10.1089/adt.2005.3.89
-
McCarty, J. H. (2005). Cell biology of the neurovascular unit: implications for drug delivery across the blood-brain barrier. Assay Drug Dev. Technol. 3, 89-95. doi: 10.1089/adt.2005.3.89
-
(2005)
Assay Drug Dev. Technol.
, vol.3
, pp. 89-95
-
-
McCarty, J.H.1
-
65
-
-
0032450274
-
Glial cell reactions in neurodegenerative diseases: Pathophysiology and therapeutic interventions
-
doi: 10.1097/00002093-199803001-00001
-
McGeer, P. L., and McGeer, E. G. (1998). Glial cell reactions in neurodegenerative diseases: pathophysiology and therapeutic interventions. Alzheimer Dis. Assoc. Disord. 12(Suppl. 2), S1-S6. doi: 10.1097/00002093-199803001-00001
-
(1998)
Alzheimer Dis. Assoc. Disord.
, vol.12
, Issue.SUPPL. 2
-
-
McGeer, P.L.1
McGeer, E.G.2
-
66
-
-
0036787810
-
Inflammatory processes in amyotrophic lateral sclerosis
-
doi: 10.1002/mus.10191
-
McGeer, P. L., and McGeer, E. G. (2002). Inflammatory processes in amyotrophic lateral sclerosis. Muscle Nerve 26, 459-470. doi: 10.1002/mus.10191
-
(2002)
Muscle Nerve
, vol.26
, pp. 459-470
-
-
McGeer, P.L.1
McGeer, E.G.2
-
67
-
-
77949262958
-
P-glycoprotein expression and function are increased in an animal model of amyotrophic lateral sclerosis
-
doi: 10.1016/j.neulet.2010.01.078
-
Milane, A., Fernandez, C., Dupuis, L., Buyse, M., Loeffler, J.-P., Farinotti, R., et al. (2010). P-glycoprotein expression and function are increased in an animal model of amyotrophic lateral sclerosis. Neurosci. Lett. 472, 166-170. doi: 10.1016/j.neulet.2010.01.078
-
(2010)
Neurosci. Lett.
, vol.472
, pp. 166-170
-
-
Milane, A.1
Fernandez, C.2
Dupuis, L.3
Buyse, M.4
Loeffler, J.-P.5
Farinotti, R.6
-
68
-
-
0141764816
-
Drug delivery to the central nervous system: A review
-
Misra, A., Ganesh, S., Shahiwala, A., and Shah, S. P. (2003). Drug delivery to the central nervous system: a review. J. Pharm. Pharm. Sci. 6, 252-273.
-
(2003)
J. Pharm. Pharm. Sci.
, vol.6
, pp. 252-273
-
-
Misra, A.1
Ganesh, S.2
Shahiwala, A.3
Shah, S.P.4
-
69
-
-
34250209501
-
Amyotrophic lateral sclerosis
-
doi: 10.1016/S0140-6736(07)60944-1
-
Mitchell, J. D., and Borasio, G. D. (2007). Amyotrophic lateral sclerosis. Lancet 369, 2031-2041. doi: 10.1016/S0140-6736(07)60944-1
-
(2007)
Lancet
, vol.369
, pp. 2031-2041
-
-
Mitchell, J.D.1
Borasio, G.D.2
-
70
-
-
79952499042
-
Disruption of neurovascular unit prior to motor neuron degeneration in amyotrophic lateral sclerosis
-
doi: 10.1002/jnr.22594
-
Miyazaki, K., Ohta, Y., Nagai, M., Morimoto, N., Kurata, T., Takehisa, Y., et al. (2011). Disruption of neurovascular unit prior to motor neuron degeneration in amyotrophic lateral sclerosis. J. Neurosci. Res. 89, 718-728. doi: 10.1002/jnr.22594
-
(2011)
J. Neurosci. Res.
, vol.89
, pp. 718-728
-
-
Miyazaki, K.1
Ohta, Y.2
Nagai, M.3
Morimoto, N.4
Kurata, T.5
Takehisa, Y.6
-
71
-
-
27144554226
-
Circulating endothelial cells in acute ischaemic stroke
-
Nadar, S. K., Lip, G. Y. H., Lee, K. W., and Blann, A. D. (2005). Circulating endothelial cells in acute ischaemic stroke. Thromb. Haemost. 94, 707-712.
-
(2005)
Thromb. Haemost.
, vol.94
, pp. 707-712
-
-
Nadar, S.K.1
Lip, G.Y.H.2
Lee, K.W.3
Blann, A.D.4
-
72
-
-
0642342131
-
Morphology and molecular properties of cellular components of normal cerebral vessels
-
(ed.)., in, (Totowa, NJ: Humana Press Inc.)
-
Nag, S. (ed.). (2003). "Morphology and molecular properties of cellular components of normal cerebral vessels, " in The Blood-Brain Barrier: Biology and Research Protocols (Totowa, NJ: Humana Press Inc.), 3-36.
-
(2003)
The Blood-Brain Barrier: Biology and Research Protocols
, pp. 3-36
-
-
Nag, S.1
-
73
-
-
71849084133
-
Impaired blood-brain and blood-spinal cord barriers in mutant SOD1-linked ALS rat
-
doi: 10.1016/j.brainres.2009.09.018
-
Nicaise, C., Mitrecic, D., Demetter, P., De Decker, R., Authelet, M., Boom, A., et al. (2009a). Impaired blood-brain and blood-spinal cord barriers in mutant SOD1-linked ALS rat. Brain Res. 1301, 152-162. doi: 10.1016/j.brainres.2009.09.018
-
(2009)
Brain Res.
, vol.1301
, pp. 152-162
-
-
Nicaise, C.1
Mitrecic, D.2
Demetter, P.3
De Decker, R.4
Authelet, M.5
Boom, A.6
-
74
-
-
59949097735
-
Aquaporin-4 overexpression in rat ALS model
-
doi: 10.1002/ar.20838
-
Nicaise, C., Soyfoo, M. S., Authelet, M., De Decker, R., Bataveljic, D., Delporte, C., et al. (2009b). Aquaporin-4 overexpression in rat ALS model. Anat. Rec. (Hoboken.) 292, 207-213. doi: 10.1002/ar.20838
-
(2009)
Anat. Rec. (Hoboken.)
, vol.292
, pp. 207-213
-
-
Nicaise, C.1
Soyfoo, M.S.2
Authelet, M.3
De Decker, R.4
Bataveljic, D.5
Delporte, C.6
-
75
-
-
77649283161
-
Aquaporin-4 as a potential marker of BBB disruption in ALS models
-
doi: 10.3109/17482960902803457
-
Nicaise, C., Soyfoo, M. S., Delporte, C., and Pochet, R. (2010). Aquaporin-4 as a potential marker of BBB disruption in ALS models. Amyotroph. Lateral Scler. 11, 253-254. doi: 10.3109/17482960902803457
-
(2010)
Amyotroph. Lateral Scler.
, vol.11
, pp. 253-254
-
-
Nicaise, C.1
Soyfoo, M.S.2
Delporte, C.3
Pochet, R.4
-
76
-
-
0032497626
-
Collagen abnormalities in the spinal cord from patients with amyotrophic lateral sclerosis
-
doi: 10.1016/S0022-510X(98)00223-8
-
Ono, S., Imai, T., Munakata, S., Takahashi, K., Kanda, F., Hashimoto, K., et al. (1998). Collagen abnormalities in the spinal cord from patients with amyotrophic lateral sclerosis. J. Neurol. Sci. 160, 140-147. doi: 10.1016/S0022-510X(98)00223-8
-
(1998)
J. Neurol. Sci.
, vol.160
, pp. 140-147
-
-
Ono, S.1
Imai, T.2
Munakata, S.3
Takahashi, K.4
Kanda, F.5
Hashimoto, K.6
-
77
-
-
0026284717
-
Advances in cell biology of blood-brain barrier transport
-
Pardridge, W. M. (1991). Advances in cell biology of blood-brain barrier transport. Semin. Cell Biol. 2, 419-426.
-
(1991)
Semin. Cell Biol.
, vol.2
, pp. 419-426
-
-
Pardridge, W.M.1
-
78
-
-
0033391691
-
Blood-brain barrier biology and methodology
-
doi: 10.3109/13550289909021285
-
Pardridge, W. M. (1999). Blood-brain barrier biology and methodology. J. Neurovirol. 5, 556-569. doi: 10.3109/13550289909021285
-
(1999)
J. Neurovirol.
, vol.5
, pp. 556-569
-
-
Pardridge, W.M.1
-
79
-
-
0036463371
-
Drug and gene targeting to the brain with molecular Trojan horses
-
doi: 10.1038/nrd725
-
Pardridge, W. M. (2002). Drug and gene targeting to the brain with molecular Trojan horses. Nat. Rev. Drug Discov. 1, 131-139. doi: 10.1038/nrd725
-
(2002)
Nat. Rev. Drug Discov.
, vol.1
, pp. 131-139
-
-
Pardridge, W.M.1
-
80
-
-
12344273726
-
The blood-brain barrier: Bottleneck in brain drug development
-
Pardridge, W. M. (2005). The blood-brain barrier: bottleneck in brain drug development. Neurorx J. Am. Soc. Exp. Neurother. 2, 3-14.
-
(2005)
Neurorx J. Am. Soc. Exp. Neurother.
, vol.2
, pp. 3-14
-
-
Pardridge, W.M.1
-
81
-
-
33747605320
-
Molecular biology of amyotrophic lateral sclerosis: Insights from genetics
-
doi: 10.1038/nrn1971
-
Pasinelli, P., and Brown, R. H. (2006). Molecular biology of amyotrophic lateral sclerosis: insights from genetics. Nat. Rev. Neurosci. 7, 710-723. doi: 10.1038/nrn1971
-
(2006)
Nat. Rev. Neurosci.
, vol.7
, pp. 710-723
-
-
Pasinelli, P.1
Brown, R.H.2
-
82
-
-
57449121882
-
Getting into the brain: Approaches to enhance brain drug delivery
-
doi: 10.2165/0023210-200923010-00003
-
Patel, M. M., Goyal, B. R., Bhadada, S. V., Bhatt, J. S., and Amin, A. F. (2009). Getting into the brain: approaches to enhance brain drug delivery. CNS Drugs 23, 35-58. doi: 10.2165/0023210-200923010-00003
-
(2009)
CNS Drugs
, vol.23
, pp. 35-58
-
-
Patel, M.M.1
Goyal, B.R.2
Bhadada, S.V.3
Bhatt, J.S.4
Amin, A.F.5
-
83
-
-
60849089627
-
CNS drug delivery systems: Novel approaches
-
doi: 10.2174/187221109787158355
-
Pathan, S. A., Iqbal, Z., Zaidi, S. M. A., Talegaonkar, S., Vohra, D., Jain, G. K., et al. (2009). CNS drug delivery systems: novel approaches. Recent Pat. Drug Deliv. Formul. 3, 71-89. doi: 10.2174/187221109787158355
-
(2009)
Recent Pat. Drug Deliv. Formul.
, vol.3
, pp. 71-89
-
-
Pathan, S.A.1
Iqbal, Z.2
Zaidi, S.M.A.3
Talegaonkar, S.4
Vohra, D.5
Jain, G.K.6
-
84
-
-
84874255781
-
Intricate interplay between astrocytes and motor neurons in ALS
-
doi: 10.1073/pnas.1222361110
-
Phatnani, H. P., Guarnieri, P., Friedman, B. A., Carrasco, M. A., Muratet, M., O'Keeffe, S., et al. (2013). Intricate interplay between astrocytes and motor neurons in ALS. Proc. Natl. Acad. Sci. U.S.A. 110, E756-E765. doi: 10.1073/pnas.1222361110
-
(2013)
Proc. Natl. Acad. Sci. U.S.A.
, vol.110
-
-
Phatnani, H.P.1
Guarnieri, P.2
Friedman, B.A.3
Carrasco, M.A.4
Muratet, M.5
O'Keeffe, S.6
-
85
-
-
84862870954
-
Neurovascular aspects of amyotrophic lateral sclerosis
-
doi: 10.1016/B978-0-12-386986-9.00004-1
-
Rodrigues, M. C. O., Hernandez-Ontiveros, D. G., Louis, M. K., Willing, A. E., Borlongan, C. V., Sanberg, P. R., et al. (2012). Neurovascular aspects of amyotrophic lateral sclerosis. Int. Rev. Neurobiol. 102, 91-106. doi: 10.1016/B978-0-12-386986-9.00004-1
-
(2012)
Int. Rev. Neurobiol.
, vol.102
, pp. 91-106
-
-
Rodrigues, M.C.O.1
Hernandez-Ontiveros, D.G.2
Louis, M.K.3
Willing, A.E.4
Borlongan, C.V.5
Sanberg, P.R.6
-
86
-
-
0027401203
-
Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis
-
doi: 10.1038/362059a0
-
Rosen, D. R., Siddique, T., Patterson, D., Figlewicz, D. A., Sapp, P., Hentati, A., et al. (1993). Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis. Nature 362, 59-62. doi: 10.1038/362059a0
-
(1993)
Nature
, vol.362
, pp. 59-62
-
-
Rosen, D.R.1
Siddique, T.2
Patterson, D.3
Figlewicz, D.A.4
Sapp, P.5
Hentati, A.6
-
87
-
-
60849093466
-
Current hypotheses for the underlying biology of amyotrophic lateral sclerosis
-
doi: 10.1002/ana.21543
-
Rothstein, J. D. (2009). Current hypotheses for the underlying biology of amyotrophic lateral sclerosis. Ann. Neurol. 65(Suppl. 1), S3-S9. doi: 10.1002/ana.21543
-
(2009)
Ann. Neurol.
, vol.65
, Issue.SUPPL. 1
-
-
Rothstein, J.D.1
-
88
-
-
0035978743
-
Amyotrophic lateral sclerosis
-
doi: 10.1056/NEJM200105313442207
-
Rowland, L. P., and Shneider, N. A. (2001). Amyotrophic lateral sclerosis. N. Engl. J. Med. 344, 1688-1700. doi: 10.1056/NEJM200105313442207
-
(2001)
N. Engl. J. Med.
, vol.344
, pp. 1688-1700
-
-
Rowland, L.P.1
Shneider, N.A.2
-
89
-
-
77949415405
-
Gray matter perfusion correlates with disease severity in ALS
-
doi: 10.1212/WNL.0b013e3181d3e2dd
-
Rule, R. R., Schuff, N., Miller, R. G., and Weiner, M. W. (2010). Gray matter perfusion correlates with disease severity in ALS. Neurology 74, 821-827. doi: 10.1212/WNL.0b013e3181d3e2dd
-
(2010)
Neurology
, vol.74
, pp. 821-827
-
-
Rule, R.R.1
Schuff, N.2
Miller, R.G.3
Weiner, M.W.4
-
90
-
-
84860730370
-
Mechanisms of dendritic cell trafficking across the blood-brain barrier
-
doi: 10.1007/s11481-011-9302-7
-
Sagar, D., Foss, C., El Baz, R., Pomper, M. G., Khan, Z. K., and Jain, P. (2012). Mechanisms of dendritic cell trafficking across the blood-brain barrier. J. Neuroimmune Pharmacol. 7, 74-94. doi: 10.1007/s11481-011-9302-7
-
(2012)
J. Neuroimmune Pharmacol.
, vol.7
, pp. 74-94
-
-
Sagar, D.1
Foss, C.2
El Baz, R.3
Pomper, M.G.4
Khan, Z.K.5
Jain, P.6
-
91
-
-
70349858276
-
Evaluation of humoral immune response in adaptive immunity in ALS patients during disease progression
-
doi: 10.1016/j.jneuroim.2009.07.011
-
Saleh, I. A., Zesiewicz, T., Xie, Y., Sullivan, K. L., Miller, A. M., Kuzmin-Nichols, N., et al. (2009). Evaluation of humoral immune response in adaptive immunity in ALS patients during disease progression. J. Neuroimmunol. 215, 96-101. doi: 10.1016/j.jneuroim.2009.07.011
-
(2009)
J. Neuroimmunol.
, vol.215
, pp. 96-101
-
-
Saleh, I.A.1
Zesiewicz, T.2
Xie, Y.3
Sullivan, K.L.4
Miller, A.M.5
Kuzmin-Nichols, N.6
-
92
-
-
84862734721
-
T-cell trafficking in the central nervous system
-
doi: 10.1111/j.1600-065X.2012.01140.x
-
Sallusto, F., Impellizzieri, D., Basso, C., Laroni, A., Uccelli, A., Lanzavecchia, A., et al. (2012). T-cell trafficking in the central nervous system. Immunol. Rev. 248, 216-227. doi: 10.1111/j.1600-065X.2012.01140.x
-
(2012)
Immunol. Rev.
, vol.248
, pp. 216-227
-
-
Sallusto, F.1
Impellizzieri, D.2
Basso, C.3
Laroni, A.4
Uccelli, A.5
Lanzavecchia, A.6
-
93
-
-
84862640700
-
Neurovascular unit: A focus on pericytes
-
doi: 10.1007/s12035-012-8244-2
-
Sá-Pereira, I., Brites, D., and Brito, M. A. (2012). Neurovascular unit: a focus on pericytes. Mol. Neurobiol. 45, 327-347. doi: 10.1007/s12035-012-8244-2
-
(2012)
Mol. Neurobiol.
, vol.45
, pp. 327-347
-
-
Sá-Pereira, I.1
Brites, D.2
Brito, M.A.3
-
94
-
-
0029812020
-
Reactive astrogliosis of the spinal cord in amyotrophic lateral sclerosis
-
doi: 10.1016/0022-510X(96)00073-1
-
Schiffer, D., Cordera, S., Cavalla, P., and Migheli, A. (1996). Reactive astrogliosis of the spinal cord in amyotrophic lateral sclerosis. J. Neurol. Sci. 139, Suppl. 27-33. doi: 10.1016/0022-510X(96)00073-1
-
(1996)
J. Neurol. Sci.
, vol.139
, Issue.SUPPL.
, pp. 27-33
-
-
Schiffer, D.1
Cordera, S.2
Cavalla, P.3
Migheli, A.4
-
95
-
-
84869082837
-
Is amyotrophic lateral sclerosis a primary astrocytic disease?
-
doi: 10.1016/j.mehy.2012.08.036
-
Sica, R. E. (2012). Is amyotrophic lateral sclerosis a primary astrocytic disease? Med. Hypotheses 79, 819-822. doi: 10.1016/j.mehy.2012.08.036
-
(2012)
Med. Hypotheses
, vol.79
, pp. 819-822
-
-
Sica, R.E.1
-
96
-
-
33846882646
-
Brain oedema in focal ischaemia: Molecular pathophysiology and theoretical implications
-
doi: 10.1016/S1474-4422(07)70055-8
-
Simard, J. M., Kent, T. A., Chen, M., Tarasov, K. V., and Gerzanich, V. (2007). Brain oedema in focal ischaemia: molecular pathophysiology and theoretical implications. Lancet Neurol. 6, 258-268. doi: 10.1016/S1474-4422(07)70055-8
-
(2007)
Lancet Neurol.
, vol.6
, pp. 258-268
-
-
Simard, J.M.1
Kent, T.A.2
Chen, M.3
Tarasov, K.V.4
Gerzanich, V.5
-
97
-
-
58149242839
-
Subcutaneous IGF-1 is not beneficial in 2-year ALS trial
-
doi: 10.1212/01.wnl.0000335970.78664.36
-
Sorenson, E. J., Windbank, A. J., Mandrekar, J. N., Bamlet, W. R., Appel, S. H., Armon, C., et al. (2008). Subcutaneous IGF-1 is not beneficial in 2-year ALS trial. Neurology 71, 1770-1775. doi: 10.1212/01.wnl.0000335970.78664.36
-
(2008)
Neurology
, vol.71
, pp. 1770-1775
-
-
Sorenson, E.J.1
Windbank, A.J.2
Mandrekar, J.N.3
Bamlet, W.R.4
Appel, S.H.5
Armon, C.6
-
98
-
-
23844538993
-
The pathobiology of amyotrophic lateral sclerosis: A proteinopathy?
-
doi: 10.1097/01.jnen.0000173889.71434.ea
-
Strong, M. J., Kesavapany, S., and Pant, H. C. (2005). The pathobiology of amyotrophic lateral sclerosis: a proteinopathy? J. Neuropathol. Exp. Neurol. 64, 649-664. doi: 10.1097/01.jnen.0000173889.71434.ea
-
(2005)
J. Neuropathol. Exp. Neurol.
, vol.64
, pp. 649-664
-
-
Strong, M.J.1
Kesavapany, S.2
Pant, H.C.3
-
99
-
-
33751229311
-
The role of excitotoxicity in the pathogenesis of amyotrophic lateral sclerosis
-
doi: 10.1016/j.bbadis.2006.05.002
-
Van Den Bosch, L., Van Damme, P., Bogaert, E., and Robberecht, W. (2006). The role of excitotoxicity in the pathogenesis of amyotrophic lateral sclerosis. Biochim. Biophys. Acta 1762, 1068-1082. doi: 10.1016/j.bbadis.2006.05.002
-
(2006)
Biochim. Biophys. Acta
, vol.1762
, pp. 1068-1082
-
-
Van Den Bosch, L.1
Van Damme, P.2
Bogaert, E.3
Robberecht, W.4
-
100
-
-
77957056987
-
Astrogliosis in amyotrophic lateral sclerosis: Role and therapeutic potential of astrocytes
-
doi: 10.1016/j.nurt.2010.05.012
-
Vargas, M. R., and Johnson, J. A. (2010). Astrogliosis in amyotrophic lateral sclerosis: role and therapeutic potential of astrocytes. Neurother. J. Am. Soc. Exp. Neurother. 7, 471-481. doi: 10.1016/j.nurt.2010.05.012
-
(2010)
Neurother. J. Am. Soc. Exp. Neurother.
, vol.7
, pp. 471-481
-
-
Vargas, M.R.1
Johnson, J.A.2
-
101
-
-
78649366182
-
No evidence of microbleeds in ALS patients at 7 Tesla MRI
-
doi: 10.3109/17482968.2010.513053
-
Verstraete, E., Biessels, G.-J., van Den Heuvel, M. P., Visser, F., Luijten, P. R., and van Den Berg, L. H. (2010). No evidence of microbleeds in ALS patients at 7 Tesla MRI. Amyotroph. Lateral Scler. 11, 555-557. doi: 10.3109/17482968.2010.513053
-
(2010)
Amyotroph. Lateral Scler.
, vol.11
, pp. 555-557
-
-
Verstraete, E.1
Biessels, G.-J.2
van Den Heuvel, M.P.3
Visser, F.4
Luijten, P.R.5
van Den Berg, L.H.6
-
102
-
-
0038730794
-
Molecular anatomy of intercellular junctions in brain endothelial and epithelial barriers: Electron microscopist's view
-
doi: 10.1016/S0165-0173(03)00177-2
-
Vorbrodt, A. W., and Dobrogowska, D. H. (2003). Molecular anatomy of intercellular junctions in brain endothelial and epithelial barriers: electron microscopist's view. Brain Res. Brain Res. Rev. 42, 221-242. doi: 10.1016/S0165-0173(03)00177-2
-
(2003)
Brain Res. Brain Res. Rev.
, vol.42
, pp. 221-242
-
-
Vorbrodt, A.W.1
Dobrogowska, D.H.2
-
103
-
-
0021360308
-
Effect of phenytoin and corticosteroids on seizures and lipid peroxidation in experimental posttraumatic epilepsy
-
doi: 10.3171/jns.1984.60.3.0467
-
Willmore, L. J., and Triggs, W. J. (1984). Effect of phenytoin and corticosteroids on seizures and lipid peroxidation in experimental posttraumatic epilepsy. J. Neurosurg. 60, 467-472. doi: 10.3171/jns.1984.60.3.0467
-
(1984)
J. Neurosurg.
, vol.60
, pp. 467-472
-
-
Willmore, L.J.1
Triggs, W.J.2
-
104
-
-
80055014830
-
Central nervous system pericytes in health and disease
-
doi: 10.1038/nn.2946
-
Winkler, E. A., Bell, R. D., and Zlokovic, B. V. (2011). Central nervous system pericytes in health and disease. Nat. Neurosci. 14, 1398-1405. doi: 10.1038/nn.2946
-
(2011)
Nat. Neurosci.
, vol.14
, pp. 1398-1405
-
-
Winkler, E.A.1
Bell, R.D.2
Zlokovic, B.V.3
-
105
-
-
84867083056
-
Blood-spinal cord barrier pericyte reductions contribute to increased capillary permeability
-
doi: 10.1038/jcbfm.2012.113
-
Winkler, E. A., Sengillo, J. D., Bell, R. D., Wang, J., and Zlokovic, B. V. (2012). Blood-spinal cord barrier pericyte reductions contribute to increased capillary permeability. J. Cereb. Blood Flow Metab. 32, 1841-1852. doi: 10.1038/jcbfm.2012.113
-
(2012)
J. Cereb. Blood Flow Metab.
, vol.32
, pp. 1841-1852
-
-
Winkler, E.A.1
Sengillo, J.D.2
Bell, R.D.3
Wang, J.4
Zlokovic, B.V.5
-
106
-
-
84872363503
-
Blood-spinal cord barrier breakdown and pericyte reductions in amyotrophic lateral sclerosis
-
doi: 10.1007/s00401-012-1039-8
-
Winkler, E. A., Sengillo, J. D., Sullivan, J. S., Henkel, J. S., Appel, S. H., and Zlokovic, B. V. (2013). Blood-spinal cord barrier breakdown and pericyte reductions in amyotrophic lateral sclerosis. Acta Neuropathol. (Berl.) 125, 111-120. doi: 10.1007/s00401-012-1039-8
-
(2013)
Acta Neuropathol. (Berl.)
, vol.125
, pp. 111-120
-
-
Winkler, E.A.1
Sengillo, J.D.2
Sullivan, J.S.3
Henkel, J.S.4
Appel, S.H.5
Zlokovic, B.V.6
-
107
-
-
9644273779
-
Inflammatory mediators and growth factors in the spinal cord of G93A SOD1 rats
-
doi: 10.1097/00001756-200411150-00016
-
Xie, Y., Weydt, P., Howland, D. S., Kliot, M., and Möller, T. (2004). Inflammatory mediators and growth factors in the spinal cord of G93A SOD1 rats. Neuroreport 15, 2513-2516. doi: 10.1097/00001756-200411150-00016
-
(2004)
Neuroreport
, vol.15
, pp. 2513-2516
-
-
Xie, Y.1
Weydt, P.2
Howland, D.S.3
Kliot, M.4
Möller, T.5
-
108
-
-
41149097086
-
ALS-causing SOD1 mutants generate vascular changes prior to motor neuron degeneration
-
doi: 10.1038/nn2073
-
Zhong, Z., Deane, R., Ali, Z., Parisi, M., Shapovalov, Y., O'Banion, M. K., et al. (2008). ALS-causing SOD1 mutants generate vascular changes prior to motor neuron degeneration. Nat. Neurosci. 11, 420-422. doi: 10.1038/nn2073
-
(2008)
Nat. Neurosci.
, vol.11
, pp. 420-422
-
-
Zhong, Z.1
Deane, R.2
Ali, Z.3
Parisi, M.4
Shapovalov, Y.5
O'Banion, M.K.6
|