메뉴 건너뛰기




Volumn 42, Issue 1, 2014, Pages 25-34

Discontinuous leading-strand synthesis: A stop-start story

Author keywords

Discontinuous replication; DNA damage; DNA replication; Leading strand priming; Replisome

Indexed keywords

BACTERIAL DNA; DNA FRAGMENT; FUNGAL DNA;

EID: 84893251073     PISSN: 03005127     EISSN: 14708752     Source Type: Journal    
DOI: 10.1042/BST20130262     Document Type: Article
Times cited : (4)

References (68)
  • 1
    • 0038497542 scopus 로고
    • Molecular structure of nucleic acids; A structure for deoxyribose nucleic acid
    • Watson, J.D. and Crick, F.H. (1953) Molecular structure of nucleic acids; a structure for deoxyribose nucleic acid. Nature 171, 737-738
    • (1953) Nature , vol.171 , pp. 737-738
    • Watson, J.D.1    Crick, F.H.2
  • 2
    • 33749048664 scopus 로고
    • Genetical implications of the structure of deoxyribonucleic acid
    • Watson, J.D. and Crick, F.H. (1953) Genetical implications of the structure of deoxyribonucleic acid. Nature 171, 964-967
    • (1953) Nature , vol.171 , pp. 964-967
    • Watson, J.D.1    Crick, F.H.2
  • 4
    • 79959431646 scopus 로고    scopus 로고
    • DNA replicases from a bacterial perspective
    • McHenry, C.S. (2011) DNA replicases from a bacterial perspective. Annu. Rev. Biochem. 80, 403-436
    • (2011) Annu. Rev. Biochem. , vol.80 , pp. 403-436
    • McHenry, C.S.1
  • 5
    • 0019223518 scopus 로고
    • Efficient in vitro replication of double-stranded DNA templates by a purified T4 bacteriophage replication system
    • Sinha, N.K., Morris, C.F. and Alberts, B.M. (1980) Efficient in vitro replication of double-stranded DNA templates by a purified T4 bacteriophage replication system. J. Biol. Chem. 255, 4290-4293
    • (1980) J. Biol. Chem. , vol.255 , pp. 4290-4293
    • Sinha, N.K.1    Morris, C.F.2    Alberts, B.M.3
  • 6
    • 0026706674 scopus 로고
    • Coordinated leading- and lagging-strand synthesis at the Escherichia coli DNA replication fork. I. Multiple effectors act to modulate Okazaki fragment size
    • Wu, C.A., Zechner, E.L. and Marians, K.J. (1992) Coordinated leading- and lagging-strand synthesis at the Escherichia coli DNA replication fork. I. Multiple effectors act to modulate Okazaki fragment size. J. Biol. Chem. 267, 4030-4044
    • (1992) J. Biol. Chem. , vol.267 , pp. 4030-4044
    • Wu, C.A.1    Zechner, E.L.2    Marians, K.J.3
  • 7
    • 0023014127 scopus 로고
    • Complete enzymatic replication of plasmids containing the origin of the Escherichia coli chromosome
    • Funnell, B.E., Baker, T.A. and Kornberg, A. (1986) Complete enzymatic replication of plasmids containing the origin of the Escherichia coli chromosome. J. Biol. Chem. 261, 5616-5624
    • (1986) J. Biol. Chem. , vol.261 , pp. 5616-5624
    • Funnell, B.E.1    Baker, T.A.2    Kornberg, A.3
  • 8
    • 0028100686 scopus 로고
    • Primase couples leading- and lagging-strand DNA synthesis from oriC
    • Hiasa, H. and Marians, K.J. (1994) Primase couples leading- and lagging-strand DNA synthesis from oriC. J. Biol. Chem. 269, 6058-6063
    • (1994) J. Biol. Chem. , vol.269 , pp. 6058-6063
    • Hiasa, H.1    Marians, K.J.2
  • 9
    • 57649129186 scopus 로고    scopus 로고
    • The replisome uses mRNA as a primer after colliding with RNA polymerase
    • Pomerantz, R.T. and O'Donnell, M. (2008) The replisome uses mRNA as a primer after colliding with RNA polymerase. Nature 456, 762-766
    • (2008) Nature , vol.456 , pp. 762-766
    • Pomerantz, R.T.1    O'Donnell, M.2
  • 10
    • 80054091679 scopus 로고    scopus 로고
    • The Escherichia coli replisome is inherently DNA damage tolerant
    • Yeeles, J.T. and Marians, K.J. (2011) The Escherichia coli replisome is inherently DNA damage tolerant. Science 334, 235-238
    • (2011) Science , vol.334 , pp. 235-238
    • Yeeles, J.T.1    Marians, K.J.2
  • 11
    • 33845330910 scopus 로고    scopus 로고
    • Replisome assembly and the direct restart of stalled replication forks
    • Heller, R.C. and Marians, K.J. (2006) Replisome assembly and the direct restart of stalled replication forks. Nat. Rev. Mol. Cell Biol. 7, 932-943
    • (2006) Nat. Rev. Mol. Cell Biol. , vol.7 , pp. 932-943
    • Heller, R.C.1    Marians, K.J.2
  • 12
    • 0022977660 scopus 로고
    • The Escherichia coli dnaB replication protein is a DNA helicase
    • LeBowitz, J.H. and McMacken, R. (1986) The Escherichia coli dnaB replication protein is a DNA helicase. J. Biol. Chem. 261, 4738-4748
    • (1986) J. Biol. Chem. , vol.261 , pp. 4738-4748
    • Lebowitz, J.H.1    McMacken, R.2
  • 13
    • 84878939444 scopus 로고    scopus 로고
    • Mechanisms for initiating cellular DNA replication
    • Costa, A., Hood, I.V. and Berger, J.M. (2013) Mechanisms for initiating cellular DNA replication. Annu. Rev. Biochem. 82, 25-54
    • (2013) Annu. Rev. Biochem. , vol.82 , pp. 25-54
    • Costa, A.1    Hood, I.V.2    Berger, J.M.3
  • 14
    • 0035830834 scopus 로고    scopus 로고
    • τ binds and organizes Escherichia coli replication proteins through distinct domains: Domain IV, located within the unique C terminus of τ, binds the replication fork, helicase, DnaB
    • Gao, D. and McHenry, C.S. (2001) τ binds and organizes Escherichia coli replication proteins through distinct domains: domain IV, located within the unique C terminus of τ, binds the replication fork, helicase, DnaB. J. Biol. Chem. 276, 4441-4446
    • (2001) J. Biol. Chem. , vol.276 , pp. 4441-4446
    • Gao, D.1    McHenry, C.S.2
  • 15
    • 0030070356 scopus 로고    scopus 로고
    • Coupling of a replicative polymerase and helicase: A τ-DnaB interaction mediates rapid replication fork movement
    • Kim, S., Dallmann, H.G., McHenry, C.S. and Marians, K.J. (1996) Coupling of a replicative polymerase and helicase: a τ-DnaB interaction mediates rapid replication fork movement. Cell 84, 643-650
    • (1996) Cell , vol.84 , pp. 643-650
    • Kim, S.1    Dallmann, H.G.2    McHenry, C.S.3    Marians, K.J.4
  • 16
    • 0029839057 scopus 로고    scopus 로고
    • τ couples the leading- and lagging-strand polymerases at the Escherichia coli DNA replication fork
    • Kim, S., Dallmann, H.G., McHenry, C.S. and Marians, K.J. (1996) τ couples the leading- and lagging-strand polymerases at the Escherichia coli DNA replication fork. J. Biol. Chem. 271, 21406-21412
    • (1996) J. Biol. Chem. , vol.271 , pp. 21406-21412
    • Kim, S.1    Dallmann, H.G.2    McHenry, C.S.3    Marians, K.J.4
  • 17
    • 77951537332 scopus 로고    scopus 로고
    • Stoichiometry and architecture of active DNA replication machinery in Escherichia coli
    • Reyes-Lamothe, R., Sherratt, D.J. and Leake, M.C. (2010) Stoichiometry and architecture of active DNA replication machinery in Escherichia coli. Science 328, 498-501
    • (2010) Science , vol.328 , pp. 498-501
    • Reyes-Lamothe, R.1    Sherratt, D.J.2    Leake, M.C.3
  • 18
    • 84856072129 scopus 로고    scopus 로고
    • Polymerase exchange during Okazaki fragment synthesis observed in living cells
    • Lia, G., Michel, B. and Allemand, J.F. (2012) Polymerase exchange during Okazaki fragment synthesis observed in living cells. Science 335, 328-331
    • (2012) Science , vol.335 , pp. 328-331
    • Lia, G.1    Michel, B.2    Allemand, J.F.3
  • 19
    • 34547730912 scopus 로고    scopus 로고
    • Characterization of a triple DNA polymerase replisome
    • McInerney, P., Johnson, A., Katz, F. and O'Donnell, M. (2007) Characterization of a triple DNA polymerase replisome. Mol. Cell 27, 527-538
    • (2007) Mol. Cell , vol.27 , pp. 527-538
    • McInerney, P.1    Johnson, A.2    Katz, F.3    O'Donnell, M.4
  • 20
    • 0029832926 scopus 로고    scopus 로고
    • The extreme C terminus of primase is required for interaction with DnaB at the replication fork
    • Tougu, K. and Marians, K.J. (1996) The extreme C terminus of primase is required for interaction with DnaB at the replication fork. J. Biol. Chem. 271, 21391-21397
    • (1996) J. Biol. Chem. , vol.271 , pp. 21391-21397
    • Tougu, K.1    Marians, K.J.2
  • 21
    • 0023646050 scopus 로고
    • The Escherichia coli preprimosome and DNA B helicase can form replication forks that move at the same rate
    • Mok, M. and Marians, K.J. (1987) The Escherichia coli preprimosome and DNA B helicase can form replication forks that move at the same rate. J. Biol. Chem. 262, 16644-16654
    • (1987) J. Biol. Chem. , vol.262 , pp. 16644-16654
    • Mok, M.1    Marians, K.J.2
  • 22
    • 0018895114 scopus 로고
    • Discontinuous DNA replication
    • Ogawa, T. and Okazaki, T. (1980) Discontinuous DNA replication. Annu. Rev. Biochem. 49, 421-457
    • (1980) Annu. Rev. Biochem. , vol.49 , pp. 421-457
    • Ogawa, T.1    Okazaki, T.2
  • 23
    • 0024849301 scopus 로고
    • Discontinuous DNA replication in a lig-7 strain of Escherichia coli is not the result of mismatch repair, nucleotide-excision repair, or the base-excision repair of DNA uracil
    • Wang, T.C. and Smith, K.C. (1989) Discontinuous DNA replication in a lig-7 strain of Escherichia coli is not the result of mismatch repair, nucleotide-excision repair, or the base-excision repair of DNA uracil. Biochem. Biophys. Res. Commun. 165, 685-688
    • (1989) Biochem. Biophys. Res. Commun. , vol.165 , pp. 685-688
    • Wang, T.C.1    Smith, K.C.2
  • 24
    • 0028240631 scopus 로고
    • Okazaki DNA fragments contain equal amounts of lagging-strand and leading-strand sequences
    • Wang, T.C. and Chen, S.H. (1994) Okazaki DNA fragments contain equal amounts of lagging-strand and leading-strand sequences. Biochem. Biophys. Res. Commun. 198, 844-849
    • (1994) Biochem. Biophys. Res. Commun. , vol.198 , pp. 844-849
    • Wang, T.C.1    Chen, S.H.2
  • 25
    • 21244442328 scopus 로고    scopus 로고
    • Discontinuous or semi-discontinuous DNA replication in Escherichia coli?
    • Wang, T.C. (2005) Discontinuous or semi-discontinuous DNA replication in Escherichia coli? BioEssays 27, 633-636
    • (2005) BioEssays , vol.27 , pp. 633-636
    • Wang, T.C.1
  • 26
    • 0017078340 scopus 로고
    • Evidence that both growing DNA chains at a replication fork are synthesized discontinuously
    • Sternglanz, R., Wang, H.F. and Donegan, J.J. (1976) Evidence that both growing DNA chains at a replication fork are synthesized discontinuously. Biochemistry 15, 1838-1843
    • (1976) Biochemistry , vol.15 , pp. 1838-1843
    • Sternglanz, R.1    Wang, H.F.2    Donegan, J.J.3
  • 27
    • 0014251791 scopus 로고
    • Mechanism of DNA chain growth. I. Possible discontinuity and unusual secondary structure of newly synthesized chains
    • Okazaki, R., Okazaki, T., Sakabe, K., Sugimoto, K. and Sugino, A. (1968) Mechanism of DNA chain growth. I. Possible discontinuity and unusual secondary structure of newly synthesized chains. Proc. Natl. Acad. Sci. U.S.A. 59, 598-605
    • (1968) Proc. Natl. Acad. Sci. U.S.A. , vol.59 , pp. 598-605
    • Okazaki, R.1    Okazaki, T.2    Sakabe, K.3    Sugimoto, K.4    Sugino, A.5
  • 28
    • 0015184718 scopus 로고
    • Slow joining of newly replicated DNA chains in DNA polymerase I-deficient Escherichia coli mutants
    • Okazaki, R., Arisawa, M. and Sugino, A. (1971) Slow joining of newly replicated DNA chains in DNA polymerase I-deficient Escherichia coli mutants. Proc. Natl. Acad. Sci. U.S.A. 68, 2954-2957
    • (1971) Proc. Natl. Acad. Sci. U.S.A. , vol.68 , pp. 2954-2957
    • Okazaki, R.1    Arisawa, M.2    Sugino, A.3
  • 29
    • 0014321811 scopus 로고
    • Mechanism of DNA chain growth, II. Accumulation of newly synthesized short chains in E coli infected with ligase-defective T4 phages
    • Sugimoto, K., Okazaki, T. and Okazaki, R. (1968) Mechanism of DNA chain growth, II. Accumulation of newly synthesized short chains in E. coli infected with ligase-defective T4 phages. Proc. Natl. Acad. Sci. U.S.A. 60, 1356-1362
    • (1968) Proc. Natl. Acad. Sci. U.S.A. , vol.60 , pp. 1356-1362
    • Sugimoto, K.1    Okazaki, T.2    Okazaki, R.3
  • 30
    • 0012670425 scopus 로고
    • Uracil incorporation: A source of pulse-labeled DNA fragments in the replication of the Escherichia coli chromosome
    • Tye, B.K., Chien, J., Lehman, I.R., Duncan, B.K. and Warner, H.R. (1978) Uracil incorporation: a source of pulse-labeled DNA fragments in the replication of the Escherichia coli chromosome. Proc. Natl. Acad. Sci. U.S.A. 75, 233-237
    • (1978) Proc. Natl. Acad. Sci. U.S.A. , vol.75 , pp. 233-237
    • Tye, B.K.1    Chien, J.2    Lehman, I.R.3    Duncan, B.K.4    Warner, H.R.5
  • 31
    • 33747332833 scopus 로고    scopus 로고
    • The replication intermediates in Escherichia coli are not the product of DNA processing or uracil excision
    • Amado, L. and Kuzminov, A. (2006) The replication intermediates in Escherichia coli are not the product of DNA processing or uracil excision. J. Biol. Chem. 281, 22635-22646
    • (2006) J. Biol. Chem. , vol.281 , pp. 22635-22646
    • Amado, L.1    Kuzminov, A.2
  • 32
    • 0014855924 scopus 로고
    • DNA replication in Escherichia coli: Location of recently incorporated thymidine within molecules of high molecular weight DNA
    • Iyer, V.N. and Lark, K.G. (1970) DNA replication in Escherichia coli: location of recently incorporated thymidine within molecules of high molecular weight DNA. Proc. Natl. Acad. Sci. U.S.A. 67, 629-636
    • (1970) Proc. Natl. Acad. Sci. U.S.A. , vol.67 , pp. 629-636
    • Iyer, V.N.1    Lark, K.G.2
  • 33
    • 0015976648 scopus 로고
    • Size distribution and molecular polarity of newly replicated DNA in Escherichia coli
    • Louarn, J.M. and Bird, R.E. (1974) Size distribution and molecular polarity of newly replicated DNA in Escherichia coli. Proc. Natl. Acad. Sci. U.S.A. 71, 329-333
    • (1974) Proc. Natl. Acad. Sci. U.S.A. , vol.71 , pp. 329-333
    • Louarn, J.M.1    Bird, R.E.2
  • 34
    • 0015517938 scopus 로고
    • Discontinuous DNA replication in vitro. I. Two distinct size classes of intermediates
    • Olivera, B.M. and Bonhoeffer, F. (1972) Discontinuous DNA replication in vitro. I. Two distinct size classes of intermediates. Nat. New Biol. 240, 233-235
    • (1972) Nat. New Biol. , vol.240 , pp. 233-235
    • Olivera, B.M.1    Bonhoeffer, F.2
  • 35
    • 0015517890 scopus 로고
    • Cross hybridization and rate of chain elongation of the two classes of DNA intermediates
    • Herrmann, R., Huf, J. and Bonhoeffer, F. (1972) Cross hybridization and rate of chain elongation of the two classes of DNA intermediates. Nat. New Biol. 240, 235-237
    • (1972) Nat. New Biol. , vol.240 , pp. 235-237
    • Herrmann, R.1    Huf, J.2    Bonhoeffer, F.3
  • 36
    • 0015517954 scopus 로고
    • Genetic control over the initiation of the synthesis of the short deoxynucleotide chains in e
    • Lark, K.G. (1972) Genetic control over the initiation of the synthesis of the short deoxynucleotide chains in E. coli. Nat. New Biol. 240, 237-240
    • (1972) Coli. Nat. New Biol. , vol.240 , pp. 237-240
    • Lark, K.G.1
  • 37
    • 0038365180 scopus 로고    scopus 로고
    • Fate of DNA replication fork encountering a single DNA lesion during oriC plasmid DNA replication in vitro
    • Higuchi, K., Katayama, T., Iwai, S., Hidaka, M., Horiuchi, T. and Maki, H. (2003) Fate of DNA replication fork encountering a single DNA lesion during oriC plasmid DNA replication in vitro. Genes Cells 8, 437-449
    • (2003) Genes Cells , vol.8 , pp. 437-449
    • Higuchi, K.1    Katayama, T.2    Iwai, S.3    Hidaka, M.4    Horiuchi, T.5    Maki, H.6
  • 38
    • 2442686846 scopus 로고    scopus 로고
    • Functional uncoupling of twin polymerases: Mechanism of polymerase dissociation from a lagging-strand block
    • McInerney, P. and O'Donnell, M. (2004) Functional uncoupling of twin polymerases: mechanism of polymerase dissociation from a lagging-strand block. J. Biol. Chem. 279, 21543-21551
    • (2004) J. Biol. Chem. , vol.279 , pp. 21543-21551
    • McInerney, P.1    O'Donnell, M.2
  • 40
    • 0014432520 scopus 로고
    • Discontinuities in the DNA synthesized in an excision-defective strain of Escherichia coli following ultraviolet irradiation
    • Rupp, W.D. and Howard-Flanders, P. (1968) Discontinuities in the DNA synthesized in an excision-defective strain of Escherichia coli following ultraviolet irradiation. J. Mol. Biol. 31, 291-304
    • (1968) J. Mol. Biol. , vol.31 , pp. 291-304
    • Rupp, W.D.1    Howard-Flanders, P.2
  • 41
    • 0000772677 scopus 로고    scopus 로고
    • DNA repair mechanisms
    • (Neidhart, F.C., ed.), American Society for Microbiology, Washington, DC
    • Rupp, W.D. (1996) DNA repair mechanisms. In Escherichia coli and Salmonella: Cellular and Molecular Biology (Neidhart, F.C., ed.), pp. 2277-2294, American Society for Microbiology, Washington, DC
    • (1996) Escherichia Coli and Salmonella: Cellular and Molecular Biology , pp. 2277-2294
    • Rupp, W.D.1
  • 42
    • 0014982055 scopus 로고
    • Usefulness of benzoylated naphthoylated DEAE-cellulose to distinguish and fractionate double-stranded DNA bearing different extents of single-stranded regions
    • Iyer, V.N. and Rupp, W.D. (1971) Usefulness of benzoylated naphthoylated DEAE-cellulose to distinguish and fractionate double-stranded DNA bearing different extents of single-stranded regions. Biochim. Biophys. Acta 228, 117-126
    • (1971) Biochim. Biophys. Acta , vol.228 , pp. 117-126
    • Iyer, V.N.1    Rupp, W.D.2
  • 43
    • 0026664596 scopus 로고
    • Similar-sized daughter-strand gaps are produced in the leading and lagging strands of DNA in UV-irradiated E coli uvrA cells
    • Wang, T.C. and Chen, S.H. (1992) Similar-sized daughter-strand gaps are produced in the leading and lagging strands of DNA in UV-irradiated E. coli uvrA cells. Biochem. Biophys. Res. Commun. 184, 1496-1503
    • (1992) Biochem. Biophys. Res. Commun. , vol.184 , pp. 1496-1503
    • Wang, T.C.1    Chen, S.H.2
  • 44
    • 0023428773 scopus 로고
    • Recovery from ultraviolet light-induced inhibition of DNA synthesis requires umuDC gene products in recA718 mutant strains but not in recA+ strains of Escherichia coli
    • Witkin, E.M., Roegner-Maniscalco, V., Sweasy, J.B. and McCall, J.O. (1987) Recovery from ultraviolet light-induced inhibition of DNA synthesis requires umuDC gene products in recA718 mutant strains but not in recA+ strains of Escherichia coli. Proc. Natl. Acad. Sci. U.S.A. 84, 6805-6809
    • (1987) Proc. Natl. Acad. Sci. U.S.A. , vol.84 , pp. 6805-6809
    • Witkin, E.M.1    Roegner-Maniscalco, V.2    Sweasy, J.B.3    McCall, J.O.4
  • 45
    • 33947327048 scopus 로고    scopus 로고
    • Replication fork stalling and cell cycle arrest in UV-irradiated Escherichia coli
    • Rudolph, C.J., Upton, A.L. and Lloyd, R.G. (2007) Replication fork stalling and cell cycle arrest in UV-irradiated Escherichia coli. Genes Dev. 21, 668-681
    • (2007) Genes Dev. , vol.21 , pp. 668-681
    • Rudolph, C.J.1    Upton, A.L.2    Lloyd, R.G.3
  • 46
    • 0036844340 scopus 로고    scopus 로고
    • Recombinational repair and restart of damaged replication forks
    • McGlynn, P. and Lloyd, R.G. (2002) Recombinational repair and restart of damaged replication forks. Nat. Rev. Mol. Cell Biol. 3, 859-870
    • (2002) Nat. Rev. Mol. Cell Biol. , vol.3 , pp. 859-870
    • McGlynn, P.1    Lloyd, R.G.2
  • 47
    • 0034737294 scopus 로고    scopus 로고
    • Modulation of RNA polymerase by (p)ppGpp reveals a RecG-dependent mechanism for replication fork progression
    • McGlynn, P. and Lloyd, R.G. (2000) Modulation of RNA polymerase by (p)ppGpp reveals a RecG-dependent mechanism for replication fork progression. Cell 101, 35-45
    • (2000) Cell , vol.101 , pp. 35-45
    • McGlynn, P.1    Lloyd, R.G.2
  • 48
    • 0348047324 scopus 로고    scopus 로고
    • RecA-dependent recovery of arrested DNA replication forks
    • Courcelle, J. and Hanawalt, P.C. (2003) RecA-dependent recovery of arrested DNA replication forks. Annu. Rev. Genet. 37, 611-646
    • (2003) Annu. Rev. Genet. , vol.37 , pp. 611-646
    • Courcelle, J.1    Hanawalt, P.C.2
  • 49
    • 34249938016 scopus 로고    scopus 로고
    • Recombination proteins and rescue of arrested replication forks
    • Michel, B., Boubakri, H., Baharoglu, Z., LeMasson, M. and Lestini, R. (2007) Recombination proteins and rescue of arrested replication forks. DNA Repair 6, 967-980
    • (2007) DNA Repair , vol.6 , pp. 967-980
    • Michel, B.1    Boubakri, H.2    Baharoglu, Z.3    Lemasson, M.4    Lestini, R.5
  • 50
    • 84862763199 scopus 로고    scopus 로고
    • The conflict between DNA replication and transcription
    • McGlynn, P., Savery, N.J. and Dillingham, M.S. (2012) The conflict between DNA replication and transcription. Mol. Microbiol. 85, 12-20
    • (2012) Mol. Microbiol. , vol.85 , pp. 12-20
    • McGlynn, P.1    Savery, N.J.2    Dillingham, M.S.3
  • 52
    • 34249941504 scopus 로고    scopus 로고
    • Avoiding and resolving conflicts between DNA replication and transcription
    • Rudolph, C.J., Dhillon, P., Moore, T. and Lloyd, R.G. (2007) Avoiding and resolving conflicts between DNA replication and transcription. DNA Repair 6, 981-993
    • (2007) DNA Repair , vol.6 , pp. 981-993
    • Rudolph, C.J.1    Dhillon, P.2    Moore, T.3    Lloyd, R.G.4
  • 54
    • 0035089132 scopus 로고    scopus 로고
    • Cytoplasmic RNA polymerase in Escherichia coli
    • Shepherd, N., Dennis, P. and Bremer, H. (2001) Cytoplasmic RNA polymerase in Escherichia coli. J. Bacteriol. 183, 2527-2534
    • (2001) J. Bacteriol. , vol.183 , pp. 2527-2534
    • Shepherd, N.1    Dennis, P.2    Bremer, H.3
  • 55
    • 0018888093 scopus 로고
    • Synthesis and activity of ribonucleic acid polymerase in Escherichia coli
    • Shepherd, N.S., Churchward, G. and Bremer, H. (1980) Synthesis and activity of ribonucleic acid polymerase in Escherichia coli. J. Bacteriol. 141, 1098-1108
    • (1980) J. Bacteriol. , vol.141 , pp. 1098-1108
    • Shepherd, N.S.1    Churchward, G.2    Bremer, H.3
  • 56
    • 22544464455 scopus 로고    scopus 로고
    • RNA polymerase modulators and DNA repair activities resolve conflicts between DNA replication and transcription
    • Trautinger, B.W., Jaktaji, R.P., Rusakova, E. and Lloyd, R.G. (2005) RNA polymerase modulators and DNA repair activities resolve conflicts between DNA replication and transcription. Mol. Cell 19, 247-258
    • (2005) Mol. Cell , vol.19 , pp. 247-258
    • Trautinger, B.W.1    Jaktaji, R.P.2    Rusakova, E.3    Lloyd, R.G.4
  • 57
    • 31844456472 scopus 로고    scopus 로고
    • Replication fork reactivation downstream of a blocked nascent leading strand
    • Heller, R.C. and Marians, K.J. (2006) Replication fork reactivation downstream of a blocked nascent leading strand. Nature 439, 557-562
    • (2006) Nature , vol.439 , pp. 557-562
    • Heller, R.C.1    Marians, K.J.2
  • 58
    • 84891075042 scopus 로고    scopus 로고
    • Dynamics of leading-strand lesion skipping by the replisome
    • Yeeles, J.T. and Marians, K.J. (2013) Dynamics of leading-strand lesion skipping by the replisome. Mol. Cell 52, 855-865
    • (2013) Mol. Cell , vol.52 , pp. 855-865
    • Yeeles, J.T.1    Marians, K.J.2
  • 59
    • 0037799191 scopus 로고    scopus 로고
    • Uncoupling of leading- and lagging-strand DNA replication during lesion bypass in vivo
    • Pages, V. and Fuchs, R.P. (2003) Uncoupling of leading- and lagging-strand DNA replication during lesion bypass in vivo. Science 300, 1300-1303
    • (2003) Science , vol.300 , pp. 1300-1303
    • Pages, V.1    Fuchs, R.P.2
  • 60
    • 14644415982 scopus 로고    scopus 로고
    • The disposition of nascent strands at stalled replication forks dictates the pathway of replisome loading during restart
    • Heller, R.C. and Marians, K.J. (2005) The disposition of nascent strands at stalled replication forks dictates the pathway of replisome loading during restart. Mol. Cell 17, 733-743
    • (2005) Mol. Cell , vol.17 , pp. 733-743
    • Heller, R.C.1    Marians, K.J.2
  • 61
    • 26644472197 scopus 로고    scopus 로고
    • Unwinding of the nascent lagging strand by Rep and PriA enables the direct restart of stalled replication forks
    • Heller, R.C. and Marians, K.J. (2005) Unwinding of the nascent lagging strand by Rep and PriA enables the direct restart of stalled replication forks. J. Biol. Chem. 280, 34143-34151
    • (2005) J. Biol. Chem. , vol.280 , pp. 34143-34151
    • Heller, R.C.1    Marians, K.J.2
  • 62
    • 0034176335 scopus 로고    scopus 로고
    • Initiation of genetic recombination and recombination-dependent replication
    • Kowalczykowski, S.C. (2000) Initiation of genetic recombination and recombination-dependent replication. Trends Biochem. Sci. 25, 156-165
    • (2000) Trends Biochem. Sci. , vol.25 , pp. 156-165
    • Kowalczykowski, S.C.1
  • 64
    • 76749090482 scopus 로고    scopus 로고
    • The processing of double-stranded DNA breaks for recombinational repair by helicase-nuclease complexes
    • Yeeles, J.T. and Dillingham, M.S. (2010) The processing of double-stranded DNA breaks for recombinational repair by helicase-nuclease complexes. DNA Repair 9, 276-285
    • (2010) DNA Repair , vol.9 , pp. 276-285
    • Yeeles, J.T.1    Dillingham, M.S.2
  • 65
  • 66
    • 76749101865 scopus 로고    scopus 로고
    • Recruitment to stalled replication forks of the PriA DNA helicase and replisome-loading activities is essential for survival
    • Gabbai, C.B. and Marians, K.J. (2010) Recruitment to stalled replication forks of the PriA DNA helicase and replisome-loading activities is essential for survival. DNA Repair 9, 202-209
    • (2010) DNA Repair , vol.9 , pp. 202-209
    • Gabbai, C.B.1    Marians, K.J.2
  • 67
    • 0037352498 scopus 로고    scopus 로고
    • PriA mediates DNA replication pathway choice at recombination intermediates
    • Xu, L. and Marians, K.J. (2003) PriA mediates DNA replication pathway choice at recombination intermediates. Mol. Cell 11, 817-826
    • (2003) Mol. Cell , vol.11 , pp. 817-826
    • Xu, L.1    Marians, K.J.2
  • 68
    • 75749150810 scopus 로고    scopus 로고
    • Direct restart of a replication fork stalled by a head-on RNA polymerase
    • Pomerantz, R.T. and O'Donnell, M. (2010) Direct restart of a replication fork stalled by a head-on RNA polymerase. Science 327, 590-592
    • (2010) Science , vol.327 , pp. 590-592
    • Pomerantz, R.T.1    O'Donnell, M.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.