메뉴 건너뛰기




Volumn 69, Issue , 2014, Pages 513-551

Nicotinic receptor antagonists as treatments for nicotine abuse

Author keywords

Nicotine analogs; Nicotine dependence; Nicotinic receptor antagonists; Relapse; Smoking cessation

Indexed keywords

ALPHA CONOTOXIN MII; AMFEBUTAMONE; AMMONIUM DERIVATIVE; BIS QUATERNARY AMMONIUM DERIVATIVE; CYTISINE; DOPAMINE; MECAMYLAMINE; NICOTINIC RECEPTOR; NICOTINIC RECEPTOR BLOCKING AGENT; QUATERNARY AMMONIUM DERIVATIVE; TETRAKIS QUATERNARY AMMONIUM DERIVATIVE; TRIS QUATERNARY AMMONIUM DERIVATIVE; UNCLASSIFIED DRUG; VARENICLINE;

EID: 84893195331     PISSN: 10543589     EISSN: 15578925     Source Type: Book Series    
DOI: 10.1016/B978-0-12-420118-7.00013-5     Document Type: Chapter
Times cited : (42)

References (127)
  • 1
    • 84893165632 scopus 로고    scopus 로고
    • Pharmacokinetics of the novel nicotinic receptor antagonist N, N'-dodecane-1,12-diyl-bis-3-picolinium dibromide in the rat
    • Albayati Z.A.F., Dwoskin L.P., Crooks P.A. Pharmacokinetics of the novel nicotinic receptor antagonist N, N'-dodecane-1,12-diyl-bis-3-picolinium dibromide in the rat. Drug Metabolism and Disposition 2008, 18:3870-3873.
    • (2008) Drug Metabolism and Disposition , vol.18 , pp. 3870-3873
    • Albayati, Z.A.F.1    Dwoskin, L.P.2    Crooks, P.A.3
  • 2
    • 0025856536 scopus 로고
    • Neuronal nicotinic acetylcholine receptors expressed in Xenopus oocytes have a pentameric quaternary structure
    • Anand R., Conroy W.G., Schoepfer R., Whiting P., Lindstrom J. Neuronal nicotinic acetylcholine receptors expressed in Xenopus oocytes have a pentameric quaternary structure. Journal of Biological Chemistry 1991, 266:11192-11198.
    • (1991) Journal of Biological Chemistry , vol.266 , pp. 11192-11198
    • Anand, R.1    Conroy, W.G.2    Schoepfer, R.3    Whiting, P.4    Lindstrom, J.5
  • 3
    • 0033173332 scopus 로고    scopus 로고
    • Ultrastructural localization of the α4-subunit of the neuronal acetylcholine nicotinic receptor in the rat substantia nigra
    • Arroyo-Jimenez M.M., Bourgeois J.P., Marubio L.M., Le Sourd A.M., Ottersen O.P., Rinvik E., et al. Ultrastructural localization of the α4-subunit of the neuronal acetylcholine nicotinic receptor in the rat substantia nigra. Journal of Neuroscience 1999, 19:6475-6487.
    • (1999) Journal of Neuroscience , vol.19 , pp. 6475-6487
    • Arroyo-Jimenez, M.M.1    Bourgeois, J.P.2    Marubio, L.M.3    Le Sourd, A.M.4    Ottersen, O.P.5    Rinvik, E.6
  • 5
    • 72949084363 scopus 로고    scopus 로고
    • Mecamylamine-A nicotinic acetylcholine receptor antagonist with potential for the treatment of neuropsychiatric disorders
    • Bacher I., Wu B., Shytle D.R., George T.P. Mecamylamine-A nicotinic acetylcholine receptor antagonist with potential for the treatment of neuropsychiatric disorders. Expert Opinion on Pharmacotherapy 2009, 10:2709-2721.
    • (2009) Expert Opinion on Pharmacotherapy , vol.10 , pp. 2709-2721
    • Bacher, I.1    Wu, B.2    Shytle, D.R.3    George, T.P.4
  • 6
    • 65249154248 scopus 로고    scopus 로고
    • Pharmacology of nicotine: Addiction, smoking-induced disease and therapeutics
    • Benowitz N.L. Pharmacology of nicotine: Addiction, smoking-induced disease and therapeutics. Annual Review of Pharmacology and Toxicology 2009, 49:57-71.
    • (2009) Annual Review of Pharmacology and Toxicology , vol.49 , pp. 57-71
    • Benowitz, N.L.1
  • 7
    • 84884579818 scopus 로고    scopus 로고
    • Neural circuitry of impulsivity in a cigarette craving paradigm
    • Article 67
    • Bourque J., Mendrek A., Dinh-Williams S.L., Potvin S. Neural circuitry of impulsivity in a cigarette craving paradigm. Front Psychiatry 2013, 4:1-9. Article 67.
    • (2013) Front Psychiatry , vol.4 , pp. 1-9
    • Bourque, J.1    Mendrek, A.2    Dinh-Williams, S.L.3    Potvin, S.4
  • 8
    • 84868094050 scopus 로고    scopus 로고
    • Preclinical evidence that activation of mesolimbic alpha 6 subunit containing nicotinic acetylcholine receptors supports nicotine addiction phenotype
    • Brunzell D.H. Preclinical evidence that activation of mesolimbic alpha 6 subunit containing nicotinic acetylcholine receptors supports nicotine addiction phenotype. Nicotine & Tobacco Research 2012, 14:1258-1269.
    • (2012) Nicotine & Tobacco Research , vol.14 , pp. 1258-1269
    • Brunzell, D.H.1
  • 9
    • 75749148728 scopus 로고    scopus 로고
    • Alpha-conotoxin MII-sensitive nicotinic acetylcholine receptors in the nucleus accumbens shell regulate progressive ratio responding maintained by nicotine
    • Brunzell D.H., Boschen K.E., Hendrick E.S., Beardsley P.M., McIntosh J.M. Alpha-conotoxin MII-sensitive nicotinic acetylcholine receptors in the nucleus accumbens shell regulate progressive ratio responding maintained by nicotine. Neuropsychopharmacology 2010, 35:665-673.
    • (2010) Neuropsychopharmacology , vol.35 , pp. 665-673
    • Brunzell, D.H.1    Boschen, K.E.2    Hendrick, E.S.3    Beardsley, P.M.4    McIntosh, J.M.5
  • 10
    • 0028983681 scopus 로고
    • β-Subunits co-determine the sensitivity of rat neuronal nicotinic receptors to antagonists
    • Cachelin A.B., Rust G. β-Subunits co-determine the sensitivity of rat neuronal nicotinic receptors to antagonists. Pflugers Archive: European Journal of Physiology 1995, 429:449.
    • (1995) Pflugers Archive: European Journal of Physiology , vol.429 , pp. 449
    • Cachelin, A.B.1    Rust, G.2
  • 14
    • 63849308882 scopus 로고    scopus 로고
    • The road to discovery of neuronal nicotinic cholinergic receptor subtypes
    • Springer, New York, NY, Nicotine psychopharmacology
    • Collins A.C., Salminen O., Marks M.J., Whiteaker P., Grady S.R. The road to discovery of neuronal nicotinic cholinergic receptor subtypes. Handbook of experimental pharmacology 2009, Vol. 192:85-112. Springer, New York, NY.
    • (2009) Handbook of experimental pharmacology , vol.192 , pp. 85-112
    • Collins, A.C.1    Salminen, O.2    Marks, M.J.3    Whiteaker, P.4    Grady, S.R.5
  • 15
    • 0026754804 scopus 로고
    • The α5 gene product assembles with multiple acetylcholine receptor subunits to form distinctive receptor subtypes in brain
    • Conroy W.G., Vernallis A.B., Berg D.K. The α5 gene product assembles with multiple acetylcholine receptor subunits to form distinctive receptor subtypes in brain. Neuron 1992, 9:679-691.
    • (1992) Neuron , vol.9 , pp. 679-691
    • Conroy, W.G.1    Vernallis, A.B.2    Berg, D.K.3
  • 16
    • 0026521447 scopus 로고
    • The mesolimbic dopaminergic system is implicated in the reinforcing properties of nicotine
    • Corrigall W.A., Franklin K.B.J., Coen K.M., Clarke P.B.S. The mesolimbic dopaminergic system is implicated in the reinforcing properties of nicotine. Psychopharmacology 1992, 107:285-289.
    • (1992) Psychopharmacology , vol.107 , pp. 285-289
    • Corrigall, W.A.1    Franklin, K.B.J.2    Coen, K.M.3    Clarke, P.B.S.4
  • 18
    • 0028805307 scopus 로고
    • 3H]dopamine release by pyridine N-substituted nicotine analogues: A new class of nicotinic antagonist
    • 3H]dopamine release by pyridine N-substituted nicotine analogues: A new class of nicotinic antagonist. Drug Development Research 1995, 36:71-82.
    • (1995) Drug Development Research , vol.36 , pp. 71-82
    • Crooks, P.A.1    Ravard, A.2    Teng, L.H.3    Dwoskin, L.P.4
  • 19
    • 0348010302 scopus 로고    scopus 로고
    • The β3 nicotinic receptor subunit: A component of α-conotoxin MII-binding nicotinic acetylcholine receptors that modulate dopamine release and related behaviors
    • Cui C., Booker T.K., Allen R.S., Grady S.R., Whiteaker P., Marks M.J., et al. The β3 nicotinic receptor subunit: A component of α-conotoxin MII-binding nicotinic acetylcholine receptors that modulate dopamine release and related behaviors. Journal of Neuroscience 2003, 23:11045-11053.
    • (2003) Journal of Neuroscience , vol.23 , pp. 11045-11053
    • Cui, C.1    Booker, T.K.2    Allen, R.S.3    Grady, S.R.4    Whiteaker, P.5    Marks, M.J.6
  • 20
    • 33847029091 scopus 로고    scopus 로고
    • Nicotinic acetylcholine receptors and nicotinic cholinergic mechanisms of the central nervous system
    • Dani J.A., Bertrand D. Nicotinic acetylcholine receptors and nicotinic cholinergic mechanisms of the central nervous system. Annual Review of Pharmacology and Toxicology 2007, 47:699-729.
    • (2007) Annual Review of Pharmacology and Toxicology , vol.47 , pp. 699-729
    • Dani, J.A.1    Bertrand, D.2
  • 21
    • 32844455908 scopus 로고    scopus 로고
    • Intravenous nicotine self-administration in rats: Effects of mecamylamine, hexamethonium and naloxone
    • DeNoble V.J., Mele P.C. Intravenous nicotine self-administration in rats: Effects of mecamylamine, hexamethonium and naloxone. Psychopharmacology 2006, 184:266-272.
    • (2006) Psychopharmacology , vol.184 , pp. 266-272
    • DeNoble, V.J.1    Mele, P.C.2
  • 22
    • 77954836905 scopus 로고    scopus 로고
    • Cholinergic modulation of locomotion and striatal dopamine release is mediated by α6α4* nicotinic acetylcholine receptors
    • Drenan R.M., Grady S.R., Steele A.D., McKinney S., Patzlaff N.E., McIntosh J.M., et al. Cholinergic modulation of locomotion and striatal dopamine release is mediated by α6α4* nicotinic acetylcholine receptors. Journal of Neuroscience 2010, 30:9877-9889.
    • (2010) Journal of Neuroscience , vol.30 , pp. 9877-9889
    • Drenan, R.M.1    Grady, S.R.2    Steele, A.D.3    McKinney, S.4    Patzlaff, N.E.5    McIntosh, J.M.6
  • 23
    • 53049110169 scopus 로고    scopus 로고
    • In vivo activation of midbrain dopamine neurons via sensitized high affinity α6* nicotinic acetylcholine receptors
    • Drenan R.M., Grady S.R., Whiteaker P., McClure-Begley T., McKinney S., Miwa J.M., et al. In vivo activation of midbrain dopamine neurons via sensitized high affinity α6* nicotinic acetylcholine receptors. Neuron 2008, 60:123-136.
    • (2008) Neuron , vol.60 , pp. 123-136
    • Drenan, R.M.1    Grady, S.R.2    Whiteaker, P.3    McClure-Begley, T.4    McKinney, S.5    Miwa, J.M.6
  • 24
    • 37349032306 scopus 로고    scopus 로고
    • Subcellular trafficking, pentameric assembly and subunit stoichiometry of neuronal nicotinic acetylcholine receptors containing fluorescently labeled α6 and β3 subunits
    • Drenan R.M., Nashmi R., Imoukhuede P., Just H., McKinney S., Lester H.A. Subcellular trafficking, pentameric assembly and subunit stoichiometry of neuronal nicotinic acetylcholine receptors containing fluorescently labeled α6 and β3 subunits. Molecular Pharmacology 2008, 73:27-41.
    • (2008) Molecular Pharmacology , vol.73 , pp. 27-41
    • Drenan, R.M.1    Nashmi, R.2    Imoukhuede, P.3    Just, H.4    McKinney, S.5    Lester, H.A.6
  • 25
    • 57649136428 scopus 로고    scopus 로고
    • Targeting nicotinic receptor antagonists as novel pharmacotherapies for tobacco dependence and relapse
    • Dwoskin L.P., Bardo M.T. Targeting nicotinic receptor antagonists as novel pharmacotherapies for tobacco dependence and relapse. Neuropsychopharmacology 2009, 34:244-246.
    • (2009) Neuropsychopharmacology , vol.34 , pp. 244-246
    • Dwoskin, L.P.1    Bardo, M.T.2
  • 26
    • 0034924993 scopus 로고    scopus 로고
    • Competitive neuronal nicotinic receptor antagonists: A new direction for drug discovery
    • Dwoskin L.P., Crooks P.A. Competitive neuronal nicotinic receptor antagonists: A new direction for drug discovery. Journal of Pharmacology and Experimental Therapeutics 2001, 298:395-402.
    • (2001) Journal of Pharmacology and Experimental Therapeutics , vol.298 , pp. 395-402
    • Dwoskin, L.P.1    Crooks, P.A.2
  • 31
    • 0032971675 scopus 로고    scopus 로고
    • Development of a novel class of subtype-selective nicotinic receptor antagonist: Pyridine-N-substituted nicotine analogs
    • Wiley Dwoskin, New York, NY, (Special Issue), B. Rudy, P. Seeburg (Eds.) Molecular and functional diversity of ion channels and receptors
    • Dwoskin L.P., Wilkins L.H., Pauly J., Crooks P.A. Development of a novel class of subtype-selective nicotinic receptor antagonist: Pyridine-N-substituted nicotine analogs. Annals of the New York academy of sciences 1999, Vol. 868. Wiley Dwoskin, New York, NY, (Special Issue). B. Rudy, P. Seeburg (Eds.).
    • (1999) Annals of the New York academy of sciences , vol.868
    • Dwoskin, L.P.1    Wilkins, L.H.2    Pauly, J.3    Crooks, P.A.4
  • 33
    • 33747188593 scopus 로고    scopus 로고
    • Cytisine for smoking cessation: A literature review and a meta-analysis
    • Etter J.-F. Cytisine for smoking cessation: A literature review and a meta-analysis. Archives of Internal Medicine 2006, 166:1553-1559.
    • (2006) Archives of Internal Medicine , vol.166 , pp. 1553-1559
    • Etter, J.-F.1
  • 34
    • 47249085129 scopus 로고    scopus 로고
    • α6 Containing nicotinic acetylcholine receptors dominate the nicotine control of dopamine neurotransmission in nucleus accumbens
    • Exley R., Clements M.A., Hartung H., McIntosh M.J., Cragg S.J. α6 Containing nicotinic acetylcholine receptors dominate the nicotine control of dopamine neurotransmission in nucleus accumbens. Neuropsychopharmacology 2008, 3:2158-2166.
    • (2008) Neuropsychopharmacology , vol.3 , pp. 2158-2166
    • Exley, R.1    Clements, M.A.2    Hartung, H.3    McIntosh, M.J.4    Cragg, S.J.5
  • 35
    • 32844465426 scopus 로고    scopus 로고
    • Neuropharmacology and potential efficacy of new treatments for tobacco dependence
    • Fagerstrom K., Balfour D.J. Neuropharmacology and potential efficacy of new treatments for tobacco dependence. Expert Opinion on Investigational Drugs 2006, 15:107-116.
    • (2006) Expert Opinion on Investigational Drugs , vol.15 , pp. 107-116
    • Fagerstrom, K.1    Balfour, D.J.2
  • 37
    • 84893184686 scopus 로고    scopus 로고
    • FDA Public Health Advisory
    • FDA Public Health Advisory Public health advisory on Chantix http://www.fda.gov/CDER/Drug/early_comm/varenicline.htm.
    • Public health advisory on Chantix
  • 38
  • 39
    • 0026593533 scopus 로고
    • A subtype of nicotinic cholinergic receptor in rat brain is composed of alpha4 and beta2 subunits and is up-regulated by chronic nicotine treatment
    • Flores C.M., Rogers S.W., Pabreza L.A., Wolfe B.B., Kellar K.J. A subtype of nicotinic cholinergic receptor in rat brain is composed of alpha4 and beta2 subunits and is up-regulated by chronic nicotine treatment. Molecular Pharmacology 1992, 41:31-37.
    • (1992) Molecular Pharmacology , vol.41 , pp. 31-37
    • Flores, C.M.1    Rogers, S.W.2    Pabreza, L.A.3    Wolfe, B.B.4    Kellar, K.J.5
  • 40
    • 0031039785 scopus 로고    scopus 로고
    • Formation of oligomers containing the β3 and β4 subunits of the rat nicotinic receptor
    • Forsayeth J.R., Kobrin E. Formation of oligomers containing the β3 and β4 subunits of the rat nicotinic receptor. Journal of Neuroscience 1997, 17:1531-1538.
    • (1997) Journal of Neuroscience , vol.17 , pp. 1531-1538
    • Forsayeth, J.R.1    Kobrin, E.2
  • 41
    • 0032934644 scopus 로고    scopus 로고
    • Noncompetitive functional inhibition at diverse, human nicotinic acetylcholine receptor subtypes by bupropion, phencyclidine, and ibogaine
    • Fryer J.D., Lukas R.J. Noncompetitive functional inhibition at diverse, human nicotinic acetylcholine receptor subtypes by bupropion, phencyclidine, and ibogaine. Journal of Pharmacology and Experimental Therapeutics 1999, 288:88-92.
    • (1999) Journal of Pharmacology and Experimental Therapeutics , vol.288 , pp. 88-92
    • Fryer, J.D.1    Lukas, R.J.2
  • 44
    • 0029903363 scopus 로고    scopus 로고
    • An oral self-administration model of nicotine preference in rats: Effects of mecamylamine
    • Glick S.D., Visker K.E., Maisonneuve J.M. An oral self-administration model of nicotine preference in rats: Effects of mecamylamine. Psychopharmacology 1996, 128:426-431.
    • (1996) Psychopharmacology , vol.128 , pp. 426-431
    • Glick, S.D.1    Visker, K.E.2    Maisonneuve, J.M.3
  • 45
    • 0030754814 scopus 로고    scopus 로고
    • Immunohistochemical localization of the nicotinic acetylcholine receptor subunit α6 to dopaminergic neurons in the substantia nigra and ventral tegmental area
    • Goldner F.M., Dineley K.T., Patrick J.W. Immunohistochemical localization of the nicotinic acetylcholine receptor subunit α6 to dopaminergic neurons in the substantia nigra and ventral tegmental area. Neuroreport 1997, 8:2739-2742.
    • (1997) Neuroreport , vol.8 , pp. 2739-2742
    • Goldner, F.M.1    Dineley, K.T.2    Patrick, J.W.3
  • 46
    • 77951006621 scopus 로고    scopus 로고
    • Nicotinic acetylcholine receptors in the mesolimbic pathway: Primary role of ventral tegmental area α6β2* receptors in mediating systemic nicotine effects on dopamine release, locomotion, and reinforcement
    • Gotti C., Guiducci S., Tedesco V., Corbiolo S., Zanetti L., Moretti M., et al. Nicotinic acetylcholine receptors in the mesolimbic pathway: Primary role of ventral tegmental area α6β2* receptors in mediating systemic nicotine effects on dopamine release, locomotion, and reinforcement. Journal of Neuroscience 2010, 30:5311-5325.
    • (2010) Journal of Neuroscience , vol.30 , pp. 5311-5325
    • Gotti, C.1    Guiducci, S.2    Tedesco, V.3    Corbiolo, S.4    Zanetti, L.5    Moretti, M.6
  • 47
    • 21744452511 scopus 로고    scopus 로고
    • Expression of nigrostriatal α6-containing nicotinic acetylcholine receptors is selectively reduced, but not eliminated, by β3 subunit gene deletion
    • Gotti C., Moretti M., Clementi F., Riganti F., McIntosh J.M., Collins A.C., et al. Expression of nigrostriatal α6-containing nicotinic acetylcholine receptors is selectively reduced, but not eliminated, by β3 subunit gene deletion. Molecular Pharmacology 2005, 67:2007-2015.
    • (2005) Molecular Pharmacology , vol.67 , pp. 2007-2015
    • Gotti, C.1    Moretti, M.2    Clementi, F.3    Riganti, F.4    McIntosh, J.M.5    Collins, A.C.6
  • 48
    • 33747422892 scopus 로고    scopus 로고
    • Brain nicotinic acetylcholine receptors: Native subtypes and their relevance
    • Gotti C., Zoli M., Clementi F. Brain nicotinic acetylcholine receptors: Native subtypes and their relevance. Trends in Pharmacological Sciences 2006, 27:482-491.
    • (2006) Trends in Pharmacological Sciences , vol.27 , pp. 482-491
    • Gotti, C.1    Zoli, M.2    Clementi, F.3
  • 49
    • 0035166601 scopus 로고    scopus 로고
    • Nicotinic agonists stimulate acetylcholine release from mouse interpeduncular nucleus: A function mediated by a different nAChR than dopamine release from striatum
    • Grady S.R., Meinerz N.M., Cao J., Reynolds A.M., Picciotto M.R., Changeux J.-P., et al. Nicotinic agonists stimulate acetylcholine release from mouse interpeduncular nucleus: A function mediated by a different nAChR than dopamine release from striatum. Journal of Neurochemistry 2001, 76:258-268.
    • (2001) Journal of Neurochemistry , vol.76 , pp. 258-268
    • Grady, S.R.1    Meinerz, N.M.2    Cao, J.3    Reynolds, A.M.4    Picciotto, M.R.5    Changeux, J.-P.6
  • 51
    • 84891552782 scopus 로고    scopus 로고
    • Efficacy of cytisine in helping smokers quit: Systematic review and meta-analysis
    • Hajek P., McRobbie H., Myers K. Efficacy of cytisine in helping smokers quit: Systematic review and meta-analysis. Thorax. 2013, 10.1136/thoraxjnl-2012-203035.
    • (2013) Thorax.
    • Hajek, P.1    McRobbie, H.2    Myers, K.3
  • 53
    • 84868154649 scopus 로고    scopus 로고
    • Development of novel pharmacotherapeutics for tobacco dependence: Progress and future directions
    • Harmey D., Griffin P.R., Kenny P.J. Development of novel pharmacotherapeutics for tobacco dependence: Progress and future directions. Nicotine & Tobacco Research 2012, 14:1300-1318.
    • (2012) Nicotine & Tobacco Research , vol.14 , pp. 1300-1318
    • Harmey, D.1    Griffin, P.R.2    Kenny, P.J.3
  • 54
    • 0029889642 scopus 로고    scopus 로고
    • Determinants of competitive antagonist sensitivity on neuronal nicotinic receptor beta subunits
    • Harvey S.C., Luetje C.W. Determinants of competitive antagonist sensitivity on neuronal nicotinic receptor beta subunits. Journal of Neuroscience 1996, 16:3798-3806.
    • (1996) Journal of Neuroscience , vol.16 , pp. 3798-3806
    • Harvey, S.C.1    Luetje, C.W.2
  • 55
    • 0029847649 scopus 로고    scopus 로고
    • Multiple determinants of dihydro-beta-erythroidine sensitivity on rat neuronal nicotinic receptor alpha subunits
    • Harvey S.C., Maddox F.N., Luetje C.W. Multiple determinants of dihydro-beta-erythroidine sensitivity on rat neuronal nicotinic receptor alpha subunits. Journal of Neurochemistry 1996, 67:1953-1959.
    • (1996) Journal of Neurochemistry , vol.67 , pp. 1953-1959
    • Harvey, S.C.1    Maddox, F.N.2    Luetje, C.W.3
  • 57
    • 0037292587 scopus 로고    scopus 로고
    • The increasing recalcitrance of smokers in clinical trials II: Pharmacotherapy trials
    • Irvin J.E., Hendricks P.S., Brandon T.H. The increasing recalcitrance of smokers in clinical trials II: Pharmacotherapy trials. Nicotine and Tobacco Research 2003, 5:27-35.
    • (2003) Nicotine and Tobacco Research , vol.5 , pp. 27-35
    • Irvin, J.E.1    Hendricks, P.S.2    Brandon, T.H.3
  • 60
    • 33745611449 scopus 로고    scopus 로고
    • Efficacy of varenicline, an alpha4beta2 nicotinic acetylcholine receptor partial agonist, vs placebo or sustained-release bupropion for smoking cessation: A randomized controlled trial
    • Jorenby D.E., Hays J.T., Rigotti N.A., Azoulay S., Watsky E.J., Williams K.E., et al. Efficacy of varenicline, an alpha4beta2 nicotinic acetylcholine receptor partial agonist, vs placebo or sustained-release bupropion for smoking cessation: A randomized controlled trial. JAMA 2006, 296:56-63.
    • (2006) JAMA , vol.296 , pp. 56-63
    • Jorenby, D.E.1    Hays, J.T.2    Rigotti, N.A.3    Azoulay, S.4    Watsky, E.J.5    Williams, K.E.6
  • 61
    • 0031892777 scopus 로고    scopus 로고
    • Differential inhibition by α-conotoxin-MII of the nicotinic stimulation of [3H]dopamine release from rat striatal synaptosomes and slices
    • Kaiser S.A., Soliakov L., Harvey S.C., Luetje C.W., Wonnacott S. Differential inhibition by α-conotoxin-MII of the nicotinic stimulation of [3H]dopamine release from rat striatal synaptosomes and slices. Journal of Neurochemistry 1998, 70:1069-1076.
    • (1998) Journal of Neurochemistry , vol.70 , pp. 1069-1076
    • Kaiser, S.A.1    Soliakov, L.2    Harvey, S.C.3    Luetje, C.W.4    Wonnacott, S.5
  • 62
    • 0011134102 scopus 로고
    • Neuromuscular blocking agents
    • MacMillan Publishing Co., New York, NY, L.S. Goodman, A. Gilman (Eds.)
    • Koelle G.B. Neuromuscular blocking agents. The pharmacological basis of therapeutic 1975, 575-588. MacMillan Publishing Co., New York, NY. L.S. Goodman, A. Gilman (Eds.).
    • (1975) The pharmacological basis of therapeutic , pp. 575-588
    • Koelle, G.B.1
  • 63
    • 16944362902 scopus 로고    scopus 로고
    • α-Conotoxin MII blocks nicotine-stimulated dopamine release in rat striatal synaptosomes
    • Kulak J.M., Nguyen T.A., Olivera B.M., McIntosh J.M. α-Conotoxin MII blocks nicotine-stimulated dopamine release in rat striatal synaptosomes. Journal of Neuroscience 1997, 17:5263-5270.
    • (1997) Journal of Neuroscience , vol.17 , pp. 5263-5270
    • Kulak, J.M.1    Nguyen, T.A.2    Olivera, B.M.3    McIntosh, J.M.4
  • 64
    • 78651375827 scopus 로고    scopus 로고
    • Expression of functional human α6β2β3* acetylcholine receptors in Xenopus laevis oocytes achieved through subunit chimeras and concatamers
    • Kuryatov A., Lindstrom J. Expression of functional human α6β2β3* acetylcholine receptors in Xenopus laevis oocytes achieved through subunit chimeras and concatamers. Molecular Pharmacology 2011, 79:126-140.
    • (2011) Molecular Pharmacology , vol.79 , pp. 126-140
    • Kuryatov, A.1    Lindstrom, J.2
  • 65
    • 19544370717 scopus 로고    scopus 로고
    • Control of the reinforcing effects of nicotine by associated environmental stimuli in animals and humans
    • Le Foll B., Goldberg S.R. Control of the reinforcing effects of nicotine by associated environmental stimuli in animals and humans. TRENDS in Pharmacological Sciences 2005, 26:287-293.
    • (2005) TRENDS in Pharmacological Sciences , vol.26 , pp. 287-293
    • Le Foll, B.1    Goldberg, S.R.2
  • 66
    • 63849121376 scopus 로고    scopus 로고
    • Effects of nicotine in experimental animals and humans: An update on addictive properties
    • Springer, New York, NY
    • Le Foll B., Goldberg S.R. Effects of nicotine in experimental animals and humans: An update on addictive properties. Handbook of experimental pharmacology 2009, Vol. 192:335-367. Springer, New York, NY.
    • (2009) Handbook of experimental pharmacology , vol.192 , pp. 335-367
    • Le Foll, B.1    Goldberg, S.R.2
  • 67
    • 0029908722 scopus 로고    scopus 로고
    • Neuronal nicotinic receptor alpha6 subunit mRNA is selectively concentrated in catecholaminergic nuclei of the rat brain
    • Le Novère N., Zoli M., Changeux J.P. Neuronal nicotinic receptor alpha6 subunit mRNA is selectively concentrated in catecholaminergic nuclei of the rat brain. European Journal of Neuroscience 1996, 8:2428-2439.
    • (1996) European Journal of Neuroscience , vol.8 , pp. 2428-2439
    • Le Novère, N.1    Zoli, M.2    Changeux, J.P.3
  • 68
    • 37349073219 scopus 로고    scopus 로고
    • Carrier mediated transport at the blood-brain barrier for the quaternary ammonium nicotinic receptor antagonist, N, N-dodecyl-bis-picolinium bromide (bPiDDB)
    • Lockman P.R., Geldenhuys W.J., Manda V., Thomas F., Crooks P.A., Dwoskin L.P., et al. Carrier mediated transport at the blood-brain barrier for the quaternary ammonium nicotinic receptor antagonist, N, N-dodecyl-bis-picolinium bromide (bPiDDB). Journal of Pharmacology and Experimental Therapeutics 2008, 324:244-250.
    • (2008) Journal of Pharmacology and Experimental Therapeutics , vol.324 , pp. 244-250
    • Lockman, P.R.1    Geldenhuys, W.J.2    Manda, V.3    Thomas, F.4    Crooks, P.A.5    Dwoskin, L.P.6
  • 70
    • 0033921876 scopus 로고    scopus 로고
    • Mecamylamine blockade of both positive and negative effects of IV nicotine in human volunteers
    • Lundahl L.H., Henningfield J.E., Lukas S.E. Mecamylamine blockade of both positive and negative effects of IV nicotine in human volunteers. Pharmacology, Biochemistry, and Behavior 2000, 66:637-643.
    • (2000) Pharmacology, Biochemistry, and Behavior , vol.66 , pp. 637-643
    • Lundahl, L.H.1    Henningfield, J.E.2    Lukas, S.E.3
  • 71
    • 32844470559 scopus 로고    scopus 로고
    • Deletion of the beta2 nicotinic acetylcholine receptor subunit alters development of tolerance to nicotine and eliminates receptor upregulation
    • McCallum S.E., Collins A.C., Paylor R., Marks M.J. Deletion of the beta2 nicotinic acetylcholine receptor subunit alters development of tolerance to nicotine and eliminates receptor upregulation. Psychopharmacology 2006, 184:314-327.
    • (2006) Psychopharmacology , vol.184 , pp. 314-327
    • McCallum, S.E.1    Collins, A.C.2    Paylor, R.3    Marks, M.J.4
  • 72
    • 0028965629 scopus 로고
    • Physiological diversity of nicotinic acetylcholine receptors expressed by vertebrate neurons
    • McGehee D.S., Role L.W. Physiological diversity of nicotinic acetylcholine receptors expressed by vertebrate neurons. Annual Review of Physiology 1995, 57:521-546.
    • (1995) Annual Review of Physiology , vol.57 , pp. 521-546
    • McGehee, D.S.1    Role, L.W.2
  • 73
    • 24044496218 scopus 로고    scopus 로고
    • A novel alpha-conotoxin, PeIA, cloned from Conus pergrandis, discriminates between rat alpha9alpha10 and alpha7 nicotinic cholinergic receptors
    • McIntosh J.M., Plazas P.V., Watkins M., Gomez-Casati M.E., Olivera B.M., Elgoyhen A.B. A novel alpha-conotoxin, PeIA, cloned from Conus pergrandis, discriminates between rat alpha9alpha10 and alpha7 nicotinic cholinergic receptors. Journal of Biological Chemistry 2005, 280:30107-30112.
    • (2005) Journal of Biological Chemistry , vol.280 , pp. 30107-30112
    • McIntosh, J.M.1    Plazas, P.V.2    Watkins, M.3    Gomez-Casati, M.E.4    Olivera, B.M.5    Elgoyhen, A.B.6
  • 74
    • 33747598710 scopus 로고    scopus 로고
    • Varenicline is a partial agonist at alpha4beta2 and a full agonist at alpha7 neuronal nicotinic receptors
    • Mihalak K.B., Carroll F.I., Luetje C.W. Varenicline is a partial agonist at alpha4beta2 and a full agonist at alpha7 neuronal nicotinic receptors. Molecular Pharmacology 2006, 70:801-805.
    • (2006) Molecular Pharmacology , vol.70 , pp. 801-805
    • Mihalak, K.B.1    Carroll, F.I.2    Luetje, C.W.3
  • 75
    • 58049091080 scopus 로고    scopus 로고
    • Diversity of vertebrate nicotinic acetylcholine receptors
    • Millar N.S., Gotti C. Diversity of vertebrate nicotinic acetylcholine receptors. Neuropharmacology 2009, 56:237-246.
    • (2009) Neuropharmacology , vol.56 , pp. 237-246
    • Millar, N.S.1    Gotti, C.2
  • 76
    • 70449510539 scopus 로고    scopus 로고
    • Efficacy of pharmacotherapies for short-term smoking abstinence: A systematic review and meta-analysis
    • Mills E.J., Wu P., Spurden D., Ebbert J.O., Wilson K. Efficacy of pharmacotherapies for short-term smoking abstinence: A systematic review and meta-analysis. Harm Reduction Journal 2009, 6:25.
    • (2009) Harm Reduction Journal , vol.6 , pp. 25
    • Mills, E.J.1    Wu, P.2    Spurden, D.3    Ebbert, J.O.4    Wilson, K.5
  • 77
    • 34047183628 scopus 로고    scopus 로고
    • Cytisine, a partial agonist of high-affinity nicotinic acetylcholine receptors, has antidepressant-like properties in male C57BL/6J mice
    • Mineur Y.S., Somenzi O., Picciotto M.R. Cytisine, a partial agonist of high-affinity nicotinic acetylcholine receptors, has antidepressant-like properties in male C57BL/6J mice. Neuropharmacology 2007, 52:1256-1262.
    • (2007) Neuropharmacology , vol.52 , pp. 1256-1262
    • Mineur, Y.S.1    Somenzi, O.2    Picciotto, M.R.3
  • 78
    • 77954941134 scopus 로고    scopus 로고
    • A comparative study of the effects of the intravenous self-administration or subcutaneous minipump infusion of nicotine on the expression of brain neuronal nicotinic receptor subtypes
    • Moretti M., Mugnaini M., Tessari M., Zoli M., Gaimarri A., Manfredi I., et al. A comparative study of the effects of the intravenous self-administration or subcutaneous minipump infusion of nicotine on the expression of brain neuronal nicotinic receptor subtypes. Molecular Pharmacology 2010, 78:287-296.
    • (2010) Molecular Pharmacology , vol.78 , pp. 287-296
    • Moretti, M.1    Mugnaini, M.2    Tessari, M.3    Zoli, M.4    Gaimarri, A.5    Manfredi, I.6
  • 79
    • 32844461047 scopus 로고    scopus 로고
    • Effect of a novel nicotinic receptor antagonist, N, N'-dodecane-1,12-diyl-bis-3-picolinium dibromide (bPiDDB), on nicotine self-administration and hyperactivity in rats
    • Neugebauer N.M., Zhang Z., Crooks P.A., Dwoskin L.P., Bardo M.T. Effect of a novel nicotinic receptor antagonist, N, N'-dodecane-1,12-diyl-bis-3-picolinium dibromide (bPiDDB), on nicotine self-administration and hyperactivity in rats. Psychopharmacology 2006, 184:426-434.
    • (2006) Psychopharmacology , vol.184 , pp. 426-434
    • Neugebauer, N.M.1    Zhang, Z.2    Crooks, P.A.3    Dwoskin, L.P.4    Bardo, M.T.5
  • 80
    • 77951032908 scopus 로고    scopus 로고
    • Activation and inhibition of mouse muscle and neuronal nicotinic acetylcholine receptors expressed in Xenopus oocytes
    • Papke R.L., Wecker L., Stitzel J.A. Activation and inhibition of mouse muscle and neuronal nicotinic acetylcholine receptors expressed in Xenopus oocytes. Journal of Pharmacology and Experimental Therapeutics 2010, 333:501-518.
    • (2010) Journal of Pharmacology and Experimental Therapeutics , vol.333 , pp. 501-518
    • Papke, R.L.1    Wecker, L.2    Stitzel, J.A.3
  • 83
    • 84878982347 scopus 로고    scopus 로고
    • Molecular mechanisms underlying behaviors related to nicotine addiction
    • Picciotto M.R., Kenny P.J. Molecular mechanisms underlying behaviors related to nicotine addiction. Cold Spring Harbor Perspectives in Medicine 2013, 3. 10.1101/cshperspect.a012112.
    • (2013) Cold Spring Harbor Perspectives in Medicine , vol.3
    • Picciotto, M.R.1    Kenny, P.J.2
  • 84
    • 58149385076 scopus 로고    scopus 로고
    • Crucial role of α4 and α6 nicotinic acetylcholine receptor subunits from ventral tegmental area in systemic nicotine self-administration
    • Pons S., Fattore L., Cossu G., Tolu S., Porcu E., McIntosh J.M., et al. Crucial role of α4 and α6 nicotinic acetylcholine receptor subunits from ventral tegmental area in systemic nicotine self-administration. Journal of Neuroscience 2008, 28:12318-12327.
    • (2008) Journal of Neuroscience , vol.28 , pp. 12318-12327
    • Pons, S.1    Fattore, L.2    Cossu, G.3    Tolu, S.4    Porcu, E.5    McIntosh, J.M.6
  • 85
    • 33845690518 scopus 로고    scopus 로고
    • Heteromeric nicotinic acetylcholine-dopamine autoreceptor complexes modulate striatal dopamine release
    • Quarta D., Ciruela F., Patkar K., Borycz J., Solinas M., Lluis C., et al. Heteromeric nicotinic acetylcholine-dopamine autoreceptor complexes modulate striatal dopamine release. Neuropsychopharmacology 2007, 32:35-42.
    • (2007) Neuropsychopharmacology , vol.32 , pp. 35-42
    • Quarta, D.1    Ciruela, F.2    Patkar, K.3    Borycz, J.4    Solinas, M.5    Lluis, C.6
  • 86
    • 39449091429 scopus 로고    scopus 로고
    • Region-specific effects of the novel nicotinic receptor antagonist N, N'-dodecane-1,12-diyl-bis-3-picolinium bromide (bPiDDB) on the nicotine-induced increase in extracellular dopamine: An in vivo reverse microdialysis study
    • Rahman S., Zhang Z., Papke R.L., Crooks P.A., Dwoskin L.P., Bardo M.T. Region-specific effects of the novel nicotinic receptor antagonist N, N'-dodecane-1,12-diyl-bis-3-picolinium bromide (bPiDDB) on the nicotine-induced increase in extracellular dopamine: An in vivo reverse microdialysis study. British Journal of Pharmacology 2008, 153:792-804.
    • (2008) British Journal of Pharmacology , vol.153 , pp. 792-804
    • Rahman, S.1    Zhang, Z.2    Papke, R.L.3    Crooks, P.A.4    Dwoskin, L.P.5    Bardo, M.T.6
  • 88
    • 32844463322 scopus 로고    scopus 로고
    • Nicotine and non-nicotine factors in cigarette addiction
    • Rose J.E. Nicotine and non-nicotine factors in cigarette addiction. Psychopharmacology 2006, 184:274-285.
    • (2006) Psychopharmacology , vol.184 , pp. 274-285
    • Rose, J.E.1
  • 89
    • 54949129115 scopus 로고    scopus 로고
    • Disrupting nicotine reinforcement from cigarette to brain
    • Rose J.E. Disrupting nicotine reinforcement from cigarette to brain. Annals of the New York Academy of Sciences 2008, 1141:233-256.
    • (2008) Annals of the New York Academy of Sciences , vol.1141 , pp. 233-256
    • Rose, J.E.1
  • 92
    • 77950027511 scopus 로고    scopus 로고
    • Reinforcing effects of nicotine and non-nicotine components of cigarette smoke
    • Rose J.E., Salley A., Behm F.M., Bates J.E., Westman E.C. Reinforcing effects of nicotine and non-nicotine components of cigarette smoke. Psychopharmacology 2010, 1:1-12.
    • (2010) Psychopharmacology , vol.1 , pp. 1-12
    • Rose, J.E.1    Salley, A.2    Behm, F.M.3    Bates, J.E.4    Westman, E.C.5
  • 93
    • 34347364721 scopus 로고    scopus 로고
    • Pharmacology of α-conotoxin MII-sensitive subtypes of nicotinic acetylcholine receptors isolated by breeding of null mutant mice
    • Salminen O., Drapeau J.A., McIntosh J.M., Collins A.C., Marks M.J., Grady S.R. Pharmacology of α-conotoxin MII-sensitive subtypes of nicotinic acetylcholine receptors isolated by breeding of null mutant mice. Molecular Pharmacology 2007, 71:1563-1571.
    • (2007) Molecular Pharmacology , vol.71 , pp. 1563-1571
    • Salminen, O.1    Drapeau, J.A.2    McIntosh, J.M.3    Collins, A.C.4    Marks, M.J.5    Grady, S.R.6
  • 94
    • 2442653986 scopus 로고    scopus 로고
    • Subunit composition and pharmacology of two classes of striatal presynaptic nicotinic acetylcholine receptors mediating dopamine release in mice
    • Salminen O., Murphy K.L., McIntosh J.M., Drago J., Marks M.J., Collins A.C., et al. Subunit composition and pharmacology of two classes of striatal presynaptic nicotinic acetylcholine receptors mediating dopamine release in mice. Molecular Pharmacology 2004, 65:1526-1535.
    • (2004) Molecular Pharmacology , vol.65 , pp. 1526-1535
    • Salminen, O.1    Murphy, K.L.2    McIntosh, J.M.3    Drago, J.4    Marks, M.J.5    Collins, A.C.6
  • 95
    • 84893159690 scopus 로고    scopus 로고
    • Sanofi Pipeline.
    • Sanofi Pipeline. (2012). http://en.sanofi-aventis.com/binaries/080212_PDF_Slides_media_tcm28-15767.pdf.
    • (2012)
  • 97
    • 0034001653 scopus 로고    scopus 로고
    • Nicotine gum as a substitute for cigarettes: A behavioral economic analysis
    • Shahan T.A., Odum A.L., Bickel W.K. Nicotine gum as a substitute for cigarettes: A behavioral economic analysis. Behavioral Pharmacology 2000, 11:71-79.
    • (2000) Behavioral Pharmacology , vol.11 , pp. 71-79
    • Shahan, T.A.1    Odum, A.L.2    Bickel, W.K.3
  • 99
    • 68349155682 scopus 로고    scopus 로고
    • The novel nicotinic receptor antagonist, N, N'-dodecane-1,12-diyl-bis-3-picolinium dibromide (bPiDDB), inhibits nicotine-evoked [3H]norepinephrine overflow from rat hippocampal slices
    • Smith A.M., Dhawan G.K., Zhang Z., Siripurapu K.B., Crooks P.A., Dwoskin L.P. The novel nicotinic receptor antagonist, N, N'-dodecane-1,12-diyl-bis-3-picolinium dibromide (bPiDDB), inhibits nicotine-evoked [3H]norepinephrine overflow from rat hippocampal slices. Biochemical Pharmacology 2009, 78:889-897.
    • (2009) Biochemical Pharmacology , vol.78 , pp. 889-897
    • Smith, A.M.1    Dhawan, G.K.2    Zhang, Z.3    Siripurapu, K.B.4    Crooks, P.A.5    Dwoskin, L.P.6
  • 101
    • 84881110933 scopus 로고    scopus 로고
    • Unraveling the neurobiology of nicotine dependence using genetically engineered mice
    • Stoker A.K., Markou A. Unraveling the neurobiology of nicotine dependence using genetically engineered mice. Current Opinion in Neurobiology 2013, 23:493-499.
    • (2013) Current Opinion in Neurobiology , vol.23 , pp. 493-499
    • Stoker, A.K.1    Markou, A.2
  • 102
    • 84886628339 scopus 로고    scopus 로고
    • Smoking cessation treatment and risk of depression, suicide, and self harm in the Clinical Practice Research Datalink prospective cohort study
    • Thomas K.H., Martin R.M., Davies N.M., Metcalfe C., Windmeijer F., Gunnel D. Smoking cessation treatment and risk of depression, suicide, and self harm in the Clinical Practice Research Datalink prospective cohort study. British Journal of Medicine 2013, 347:f5704.
    • (2013) British Journal of Medicine , vol.347
    • Thomas, K.H.1    Martin, R.M.2    Davies, N.M.3    Metcalfe, C.4    Windmeijer, F.5    Gunnel, D.6
  • 103
    • 84859742106 scopus 로고    scopus 로고
    • AT-1001: A high affinity and selective α3β4 nicotinic acetylcholine receptor antagonist blocks nicotine self-administration in rats
    • Toll L., Zaveri N.T., Polgar W.E., Jiang F., Khroyan T.V., Zhou W., et al. AT-1001: A high affinity and selective α3β4 nicotinic acetylcholine receptor antagonist blocks nicotine self-administration in rats. Neuropsychopharmacology 2012, 37:1367-1376.
    • (2012) Neuropsychopharmacology , vol.37 , pp. 1367-1376
    • Toll, L.1    Zaveri, N.T.2    Polgar, W.E.3    Jiang, F.4    Khroyan, T.V.5    Zhou, W.6
  • 104
    • 27144526186 scopus 로고    scopus 로고
    • Nicotinic cholinergic receptors in the rat cerebellum: Multiple heteromeric subtypes
    • Turner J.R., Kellar K.J. Nicotinic cholinergic receptors in the rat cerebellum: Multiple heteromeric subtypes. Journal of Neuroscience 2005, 25:9258-9265.
    • (2005) Journal of Neuroscience , vol.25 , pp. 9258-9265
    • Turner, J.R.1    Kellar, K.J.2
  • 105
    • 84870868751 scopus 로고    scopus 로고
    • Utilizing a multimodal assessment strategy to examine variations of impulsivity among young adults engaged in co-occurring smoking and binge drinking behaviors
    • VanderVeen J.W., Cohen L.M., Watson N.L. Utilizing a multimodal assessment strategy to examine variations of impulsivity among young adults engaged in co-occurring smoking and binge drinking behaviors. Drug and Alcohol Dependence 2012, 127:150-155.
    • (2012) Drug and Alcohol Dependence , vol.127 , pp. 150-155
    • VanderVeen, J.W.1    Cohen, L.M.2    Watson, N.L.3
  • 106
    • 0024474491 scopus 로고
    • Distribution of alpha2, alpha3, alpha4, and beta2 neuronal nicotinic receptor subunit mRNAs in the central nervous system: A hybridization histochemical study in the rat
    • Wada E., Wada K., Boulter J., Deneris E., Heinemann S., Patrick J., et al. Distribution of alpha2, alpha3, alpha4, and beta2 neuronal nicotinic receptor subunit mRNAs in the central nervous system: A hybridization histochemical study in the rat. Journal of Comparative Neurology 1989, 284:314-335.
    • (1989) Journal of Comparative Neurology , vol.284 , pp. 314-335
    • Wada, E.1    Wada, K.2    Boulter, J.3    Deneris, E.4    Heinemann, S.5    Patrick, J.6
  • 111
    • 33846647034 scopus 로고    scopus 로고
    • Effectiveness of smoking cessation therapies: A systematic review and meta-analysis
    • Wu P., Wilson K., Dimoulas P., Mills E.J. Effectiveness of smoking cessation therapies: A systematic review and meta-analysis. BMC Public Health 2006, 6:300.
    • (2006) BMC Public Health , vol.6 , pp. 300
    • Wu, P.1    Wilson, K.2    Dimoulas, P.3    Mills, E.J.4
  • 112
    • 33748927988 scopus 로고    scopus 로고
    • Sazetidine-A, a novel ligand that desensitizes alpha4beta2 nicotinic acetylcholine receptors without activating them
    • Xiao Y., Fan H., Musachio J.L., Wei Z.L., Chellappan S.K., Kozikowski A.P., et al. Sazetidine-A, a novel ligand that desensitizes alpha4beta2 nicotinic acetylcholine receptors without activating them. Molecular Pharmacology 2006, 70:1454-1460.
    • (2006) Molecular Pharmacology , vol.70 , pp. 1454-1460
    • Xiao, Y.1    Fan, H.2    Musachio, J.L.3    Wei, Z.L.4    Chellappan, S.K.5    Kozikowski, A.P.6
  • 115
    • 33845583175 scopus 로고    scopus 로고
    • An uncontrolled trial of cytisine (Tabex) for smoking cessation
    • Zatonski W., Cedzynska M., Tutka P., West R. An uncontrolled trial of cytisine (Tabex) for smoking cessation. Tobacco Control 2006, 15:481-484.
    • (2006) Tobacco Control , vol.15 , pp. 481-484
    • Zatonski, W.1    Cedzynska, M.2    Tutka, P.3    West, R.4
  • 117
    • 75449111472 scopus 로고    scopus 로고
    • Novel bis-2,2,6,6-tetramethylpiperidine (bis-TMP) and bis-mecamylamine antagonists at neuronal nicotinic receptors mediating nicotine-evoked dopamine release
    • Zhang Z., Pivavarchyk M., Subramanian K.L., Deaciuc A.G., Dwoskin L.P., Crooks P.A. Novel bis-2,2,6,6-tetramethylpiperidine (bis-TMP) and bis-mecamylamine antagonists at neuronal nicotinic receptors mediating nicotine-evoked dopamine release. Bioorganic and Medicinal Chemistry Letters 2010, 20:1420-1423.
    • (2010) Bioorganic and Medicinal Chemistry Letters , vol.20 , pp. 1420-1423
    • Zhang, Z.1    Pivavarchyk, M.2    Subramanian, K.L.3    Deaciuc, A.G.4    Dwoskin, L.P.5    Crooks, P.A.6
  • 118
    • 54049099101 scopus 로고    scopus 로고
    • Tetrakis-Azaaromatic quaternary ammonium: Selective neuronal nicotinic receptor antagonists at subtypes that mediate nicotine-evoked dopamine release
    • Zhang Z., Zheng G., Pivavarchyk M., Deaciuc A.G., Dwoskin L.P., Crooks P.A. tetrakis-Azaaromatic quaternary ammonium: Selective neuronal nicotinic receptor antagonists at subtypes that mediate nicotine-evoked dopamine release. Bioorganic and Medicinal Chemistry Letters 2008, 18:5753-5757.
    • (2008) Bioorganic and Medicinal Chemistry Letters , vol.18 , pp. 5753-5757
    • Zhang, Z.1    Zheng, G.2    Pivavarchyk, M.3    Deaciuc, A.G.4    Dwoskin, L.P.5    Crooks, P.A.6
  • 119
    • 78650514641 scopus 로고    scopus 로고
    • Novel bis-, tris-, and tetrakis tertiary amino analogs as antagonists at neuronal nicotinic receptors that mediate nicotine-evoked dopamine release
    • Zhang Z., Zheng G., Pivavarchyk M., Deaciuc A.G., Dwoskin L.P., Crooks P.A. Novel bis-, tris-, and tetrakis tertiary amino analogs as antagonists at neuronal nicotinic receptors that mediate nicotine-evoked dopamine release. Bioorganic and Medicinal Chemistry Letters 2011, 21:88-91.
    • (2011) Bioorganic and Medicinal Chemistry Letters , vol.21 , pp. 88-91
    • Zhang, Z.1    Zheng, G.2    Pivavarchyk, M.3    Deaciuc, A.G.4    Dwoskin, L.P.5    Crooks, P.A.6
  • 120
    • 33644974211 scopus 로고    scopus 로고
    • QSAR modeling of mono- and bis-quaternary ammonium salts that act as antagonists at neuronal nicotinic acetylcholine receptors mediating dopamine release
    • Zheng F., Bayram E., Sumithran S.P., Ayers J.T., Zhan C.G., Schmitt J.D., et al. QSAR modeling of mono- and bis-quaternary ammonium salts that act as antagonists at neuronal nicotinic acetylcholine receptors mediating dopamine release. Bioorganic and Medicinal Chemistry 2006, 14:3017-3037.
    • (2006) Bioorganic and Medicinal Chemistry , vol.14 , pp. 3017-3037
    • Zheng, F.1    Bayram, E.2    Sumithran, S.P.3    Ayers, J.T.4    Zhan, C.G.5    Schmitt, J.D.6
  • 121
    • 66449132134 scopus 로고    scopus 로고
    • max) of quaternary ammonium antagonists for S-(-)-nicotine-evoked dopamine release from dopaminergic nerve terminals in rat striatum
    • max) of quaternary ammonium antagonists for S-(-)-nicotine-evoked dopamine release from dopaminergic nerve terminals in rat striatum. Bioorganic and Medicinal Chemistry 2009, 17:4477-4485.
    • (2009) Bioorganic and Medicinal Chemistry , vol.17 , pp. 4477-4485
    • Zheng, F.1    McConell, M.2    Zhan, C.-G.3    Dwoskin, L.P.4    Crooks, P.A.5
  • 122
    • 35848943867 scopus 로고    scopus 로고
    • Tris-Azaaromatic quaternary ammonium salts: Novel templates as antagonists at nicotinic receptors mediating nicotine-evoked dopamine release
    • Zheng G., Sumithran S.P., Deaciuc A.G., Dwoskin L.P., Crooks P.A. tris-Azaaromatic quaternary ammonium salts: Novel templates as antagonists at nicotinic receptors mediating nicotine-evoked dopamine release. Bioorganic and Medicinal Chemistry Letters 2007, 17:6701-6706.
    • (2007) Bioorganic and Medicinal Chemistry Letters , vol.17 , pp. 6701-6706
    • Zheng, G.1    Sumithran, S.P.2    Deaciuc, A.G.3    Dwoskin, L.P.4    Crooks, P.A.5
  • 124
    • 35848945253 scopus 로고    scopus 로고
    • Bis-Azaaromatic quaternary ammonium salts as antagonists at nicotinic receptors mediating nicotine-evoked dopamine release: An investigation of binding conformation
    • Zheng G., Zhang Z., Pivarvarchyk M., Deaciuc A.G., Dwoskin L.P., Crooks P.A. bis-Azaaromatic quaternary ammonium salts as antagonists at nicotinic receptors mediating nicotine-evoked dopamine release: An investigation of binding conformation. Bioorganic and Medicinal Chemistry Letters 2007, 17:6734-6738.
    • (2007) Bioorganic and Medicinal Chemistry Letters , vol.17 , pp. 6734-6738
    • Zheng, G.1    Zhang, Z.2    Pivarvarchyk, M.3    Deaciuc, A.G.4    Dwoskin, L.P.5    Crooks, P.A.6
  • 126
    • 0345131682 scopus 로고    scopus 로고
    • Identification of four classes of brain nicotinic receptors using beta2 mutant mice
    • Zoli M., Lena C., Picciotto M.R., Changeux J.P. Identification of four classes of brain nicotinic receptors using beta2 mutant mice. Journal of Neuroscience 1998, 18:4461-4472.
    • (1998) Journal of Neuroscience , vol.18 , pp. 4461-4472
    • Zoli, M.1    Lena, C.2    Picciotto, M.R.3    Changeux, J.P.4
  • 127
    • 44249092541 scopus 로고    scopus 로고
    • Sazetidine-A is a potent and selective agonist at native and recombinant alpha 4 beta 2 nicotinic acetylcholine receptors
    • Zwart R., Carbone A.L., Moroni M., Bermudez I., Mogg A.J., Folly E.A., et al. Sazetidine-A is a potent and selective agonist at native and recombinant alpha 4 beta 2 nicotinic acetylcholine receptors. Molecular Pharmacology 2008, 73:1834-1843.
    • (2008) Molecular Pharmacology , vol.73 , pp. 1834-1843
    • Zwart, R.1    Carbone, A.L.2    Moroni, M.3    Bermudez, I.4    Mogg, A.J.5    Folly, E.A.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.