Norcantharidin induced DU145 cell apoptosis through ROS-mediated mitochondrial dysfunction and energy depletion

PLoS ONE

Volumn 8, Issue 12, 2013, Pages

  Shen, Bo ^a   He, Pei Jie ^a   Shao, Chun Lin ^a  

^a FUDAN UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATE; CYCLINE; CYTOCHROME C; MANGANESE SUPEROXIDE DISMUTASE; NORCANTHARIDIN; REACTIVE OXYGEN METABOLITE;

ANTIGEN EXPRESSION; ANTINEOPLASTIC ACTIVITY; ANTIPROLIFERATIVE ACTIVITY; APOPTOSIS; ARTICLE; CANCER CELL; CELL PROLIFERATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; DNA DAMAGE; DOWN REGULATION; ENZYME RELEASE; HUMAN; HUMAN CELL; MALE; MICRONUCLEUS; MITOCHONDRIAL MEMBRANE POTENTIAL; NUCLEAR SHAPE; PROSTATE CANCER;

ADENOSINE TRIPHOSPHATE; AMP-ACTIVATED PROTEIN KINASES; ANTINEOPLASTIC AGENTS; APOPTOSIS; BICYCLO COMPOUNDS, HETEROCYCLIC; BISBENZIMIDAZOLE; BLOTTING, WESTERN; CELL LINE, TUMOR; CELL PROLIFERATION; CYTOCHROMES C; DOSE-RESPONSE RELATIONSHIP, DRUG; FLOW CYTOMETRY; HUMANS; IN SITU NICK-END LABELING; MALE; MEMBRANE POTENTIAL, MITOCHONDRIAL; MICRONUCLEUS TESTS; MITOCHONDRIA; PROLIFERATING CELL NUCLEAR ANTIGEN; PROSTATIC NEOPLASMS; REACTIVE OXYGEN SPECIES; SUPEROXIDE DISMUTASE;

EID: 84893194103     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0084610     Document Type: Article

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