Norcantharidin induces cell cycle arrest and inhibits progression of human leukemic Jurkat T cells through mitogen-activated protein kinase-mediated regulation of interleukin-2 production

Toxicology in Vitro

Volumn 25, Issue 1, 2011, Pages 206-212

  Liao, Hui Fen ^a,b   Chen, Yu Jen ^c   Chou, Chin Hung ^a   Wang, Fang Wei ^a   Kuo, Cheng Deng ^a  

^a TAIPEI VETERANS GENERAL HOSPITAL   (Taiwan)

^b NATIONAL CHIAYI UNIVERSITY   (Taiwan)

^c MACKAY MEMORIAL HOSPITAL   (Taiwan)

Author keywords

Calcineurin; Cytokines; Mitogen activated protein kinases; Norcantharidin

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; ANTHRA[1,9 CD]PYRAZOL 6(2H) ONE; CALCINEURIN; CHEMOKINE; CYCLOSPORIN A; CYTOKINE; INTERLEUKIN 2; INTERLEUKIN 8; IONOMYCIN; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE P38; NORCANTHARIDIN; PHORBOL 13 ACETATE 12 MYRISTATE; PHOSPHATASE; TUMOR NECROSIS FACTOR ALPHA;

ARTICLE; CANCER INHIBITION; CELL ACTIVATION; CELL CYCLE ARREST; CELL CYCLE G2 PHASE; CELL CYCLE M PHASE; CELL VIABILITY; CHEMOPROPHYLAXIS; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RELEASE; DOWN REGULATION; DRUG ACTIVITY; ENZYME ACTIVITY; HUMAN; HUMAN CELL; LEUKEMIA CELL LINE; TUMOR CELL; UPREGULATION;

ANTINEOPLASTIC AGENTS; BICYCLO COMPOUNDS, HETEROCYCLIC; CALCINEURIN; CARCINOGENS; CELL CYCLE; CELL SURVIVAL; DOWN-REGULATION; G2 PHASE; HUMANS; INTERLEUKIN-2; INTERLEUKIN-8; JURKAT CELLS; LEUKEMIA, T-CELL; MAP KINASE SIGNALING SYSTEM; PHOSPHORIC MONOESTER HYDROLASES; TUMOR NECROSIS FACTOR-ALPHA; UP-REGULATION;

EID: 78650522632     PISSN: 08872333     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tiv.2010.11.001     Document Type: Article

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