Akt2/LDLr double knockout mice display impaired glucose tolerance and develop more complex atherosclerotic plaques than LDLr knockout mice

Cardiovascular Research

Volumn 101, Issue 2, 2014, Pages 277-287

  Rensing, Katrijn L ^a   De Jager, Saskia C A ^b   Stroes, Erik S ^a   Vos, Mariska ^c   Twickler, Marcel Th B ^d   Dallinga Thie, Geesje M ^a,c   De Vries, Carlie J M ^c   Kuiper, Johan ^b   Bot, Ilze ^b   Von Der Thüsen, Jan H ^e  

^a ACADEMIC MEDICAL CENTER   (Netherlands)

^b LEIDEN UNIVERSITY   (Netherlands)

^c UNIVERSITY OF AMSTERDAM   (Netherlands)

^d ANTWERP UNIVERSITY HOSPITAL   (Belgium)

^e MEDICAL CENTER HAAGLANDEN   (Netherlands)

Author keywords

Akt2 LDLr dKO; Atherosclerosis; Diabetes; Mouse model

Indexed keywords

CHOLESTEROL; COLLAGEN; GLUCOSE; INSULIN; LOW DENSITY LIPOPROTEIN RECEPTOR; MESSENGER RNA; METALLOPROTEINASE; PROTEIN KINASE B BETA; TISSUE INHIBITOR OF METALLOPROTEINASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; AORTA ATHEROSCLEROSIS; AORTA ROOT; ARTICLE; ATHEROSCLEROTIC PLAQUE; CAROTID ATHEROSCLEROSIS; CELL MIGRATION; CELL PROLIFERATION; CHOLESTEROL BLOOD LEVEL; CONTROLLED STUDY; DISEASE COURSE; GLUCOSE BLOOD LEVEL; IMPAIRED GLUCOSE TOLERANCE; IN VITRO STUDY; INSULIN BLOOD LEVEL; INSULIN RESISTANCE; KNOCKOUT MOUSE; MACROPHAGE; MALE; MOUSE; NICK END LABELING; NONHUMAN; ORAL GLUCOSE TOLERANCE TEST; PHENOTYPE; PRIORITY JOURNAL; SMOOTH MUSCLE FIBER; VASCULAR SMOOTH MUSCLE; ZYMOGRAPHY;

AKT2/LDLR DKO; ATHEROSCLEROSIS; DIABETES; MOUSE MODEL;

ANIMALS; AORTIC DISEASES; APOPTOSIS; ATHEROSCLEROSIS; BIOLOGICAL MARKERS; BLOOD GLUCOSE; CAROTID ARTERY DISEASES; CELL MOVEMENT; CELL PROLIFERATION; CELLS, CULTURED; COLLAGEN; DISEASE MODELS, ANIMAL; GELATINASES; GENETIC PREDISPOSITION TO DISEASE; GLUCOSE INTOLERANCE; INSULIN; INSULIN RESISTANCE; LIPIDS; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MUSCLE, SMOOTH, VASCULAR; MYOCYTES, SMOOTH MUSCLE; NECROSIS; PHENOTYPE; PLAQUE, ATHEROSCLEROTIC; PROTO-ONCOGENE PROTEINS C-AKT; RECEPTORS, LDL; TIME FACTORS; TISSUE INHIBITOR OF METALLOPROTEINASES;

EID: 84893136611     PISSN: 00086363     EISSN: 17553245     Source Type: Journal    
DOI: 10.1093/cvr/cvt252     Document Type: Article

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