-
1
-
-
80052696272
-
MeCP2 and Rett syndrome: reversibility and potential avenues for therapy
-
Gadalla, K.K., Bailey, M.E. and Cobb, S.R. (2011) MeCP2 and Rett syndrome: reversibility and potential avenues for therapy. Biochem. J., 439, 1-14.
-
(2011)
Biochem. J.
, vol.439
, pp. 1-14
-
-
Gadalla, K.K.1
Bailey, M.E.2
Cobb, S.R.3
-
2
-
-
0032830639
-
Rett syndrome is caused by mutations in X-linked MECP2, encoding methyl-CpG-binding protein 2
-
Amir, R.E., Van den Veyver, I.B., Wan, M., Tran, C.Q., Francke, U. and Zoghbi, H.Y. (1999) Rett syndrome is caused by mutations in X-linked MECP2, encoding methyl-CpG-binding protein 2. Nat. Genet., 23, 185-188.
-
(1999)
Nat. Genet.
, vol.23
, pp. 185-188
-
-
Amir, R.E.1
Van den Veyver, I.B.2
Wan, M.3
Tran, C.Q.4
Francke, U.5
Zoghbi, H.Y.6
-
3
-
-
0242332183
-
Derepression of BDNF transcription involves calcium-dependent phosphorylation of MeCP2
-
Chen, W.G., Chang, Q., Lin, Y., Meissner, A., West, A.E., Griffith, E.C., Jaenisch, R. and Greenberg, M.E. (2003) Derepression of BDNF transcription involves calcium-dependent phosphorylation of MeCP2. Science, 302, 885-889.
-
(2003)
Science
, vol.302
, pp. 885-889
-
-
Chen, W.G.1
Chang, Q.2
Lin, Y.3
Meissner, A.4
West, A.E.5
Griffith, E.C.6
Jaenisch, R.7
Greenberg, M.E.8
-
4
-
-
11244328520
-
Loss of silent-chromatin looping and impaired imprinting ofDLX5in Rett syndrome
-
Horike, S., Cai, S., Miyano, M., Cheng, J.F. and Kohwi-Shigematsu, T. (2005) Loss of silent-chromatin looping and impaired imprinting ofDLX5in Rett syndrome. Nat. Genet., 37, 31-40.
-
(2005)
Nat. Genet.
, vol.37
, pp. 31-40
-
-
Horike, S.1
Cai, S.2
Miyano, M.3
Cheng, J.F.4
Kohwi-Shigematsu, T.5
-
5
-
-
34748831111
-
MeCP2 controls excitatory synaptic strength by regulating glutamatergic synapse number
-
Chao, H.T., Zoghbi, H.Y. and Rosenmund, C. (2007) MeCP2 controls excitatory synaptic strength by regulating glutamatergic synapse number. Neuron, 56, 58-65.
-
(2007)
Neuron
, vol.56
, pp. 58-65
-
-
Chao, H.T.1
Zoghbi, H.Y.2
Rosenmund, C.3
-
6
-
-
84856286525
-
Crh and Oprm1 mediate anxiety-related behavior and social approach in a mouse model of MECP2 duplication syndrome
-
Samaco, R.C., Mandel-Brehm, C., McGraw, C.M., Shaw, C.A., McGill, B.E. and Zoghbi, H.Y. (2012) Crh and Oprm1 mediate anxiety-related behavior and social approach in a mouse model of MECP2 duplication syndrome. Nat. Genet., 44, 206-211.
-
(2012)
Nat. Genet.
, vol.44
, pp. 206-211
-
-
Samaco, R.C.1
Mandel-Brehm, C.2
McGraw, C.M.3
Shaw, C.A.4
McGill, B.E.5
Zoghbi, H.Y.6
-
7
-
-
0032574977
-
Transcriptional repression by the methyl-CpG-binding protein MeCP2 involves a histone deacetylase complex
-
Nan, X., Ng, H.H., Johnson, C.A., Laherty, C.D., Turner, B.M., Eisenman, R.N. and Bird, A. (1998) Transcriptional repression by the methyl-CpG-binding protein MeCP2 involves a histone deacetylase complex. Nature, 393, 386-389.
-
(1998)
Nature
, vol.393
, pp. 386-389
-
-
Nan, X.1
Ng, H.H.2
Johnson, C.A.3
Laherty, C.D.4
Turner, B.M.5
Eisenman, R.N.6
Bird, A.7
-
8
-
-
0031837109
-
Methylated DNA and MeCP2 recruit histone deacetylase to repress transcription
-
Jones, P.L., Veenstra, G.J., Wade, P.A., Vermaak, D., Kass, S.U., Landsberger, N., Strouboulis, J. and Wolffe, A.P. (1998) Methylated DNA and MeCP2 recruit histone deacetylase to repress transcription. Nat. Genet., 19, 187-191.
-
(1998)
Nat. Genet.
, vol.19
, pp. 187-191
-
-
Jones, P.L.1
Veenstra, G.J.2
Wade, P.A.3
Vermaak, D.4
Kass, S.U.5
Landsberger, N.6
Strouboulis, J.7
Wolffe, A.P.8
-
9
-
-
45849105557
-
MeCP2, a key contributor to neurological disease, activates and represses transcription
-
Chahrour, M., Jung, S.Y., Shaw, C., Zhou, X., Wong, S.T., Qin, J. and Zoghbi, H.Y. (2008) MeCP2, a key contributor to neurological disease, activates and represses transcription. Science, 320, 1224-1229.
-
(2008)
Science
, vol.320
, pp. 1224-1229
-
-
Chahrour, M.1
Jung, S.Y.2
Shaw, C.3
Zhou, X.4
Wong, S.T.5
Qin, J.6
Zoghbi, H.Y.7
-
10
-
-
37649022627
-
Integrated epigenomic analyses of neuronal MeCP2 reveal a role for long-range interaction with active genes
-
Yasui, D.H., Peddada, S., Bieda, M.C., Vallero, R.O., Hogart, A., Nagarajan, R.P., Thatcher, K.N., Farnham, P.J. and Lasalle, J.M. (2007) Integrated epigenomic analyses of neuronal MeCP2 reveal a role for long-range interaction with active genes. Proc. Natl Acad. Sci.USA, 104, 19416-19421.
-
(2007)
Proc. Natl Acad. Sci.USA
, vol.104
, pp. 19416-19421
-
-
Yasui, D.H.1
Peddada, S.2
Bieda, M.C.3
Vallero, R.O.4
Hogart, A.5
Nagarajan, R.P.6
Thatcher, K.N.7
Farnham, P.J.8
Lasalle, J.M.9
-
11
-
-
29144447632
-
Regulation of RNA splicing by the methylation-dependent transcriptional repressor methyl-CpG binding protein 2
-
Young, J.I., Hong, E.P., Castle, J.C., Crespo-Barreto, J., Bowman, A.B., Rose, M.F., Kang, D., Richman, R., Johnson, J.M., Berget, S. et al. (2005) Regulation of RNA splicing by the methylation-dependent transcriptional repressor methyl-CpG binding protein 2. Proc. Natl Acad. Sci. USA, 102, 17551-17558.
-
(2005)
Proc. Natl Acad. Sci. USA
, vol.102
, pp. 17551-17558
-
-
Young, J.I.1
Hong, E.P.2
Castle, J.C.3
Crespo-Barreto, J.4
Bowman, A.B.5
Rose, M.F.6
Kang, D.7
Richman, R.8
Johnson, J.M.9
Berget, S.10
-
12
-
-
14044252235
-
Epigenetic overlap in autism-spectrum neurodevelopmental disorders: MECP2 deficiency causes reduced expression of UBE3A and GABRB3
-
Samaco, R.C., Hogart, A. and LaSalle, J.M. (2005) Epigenetic overlap in autism-spectrum neurodevelopmental disorders: MECP2 deficiency causes reduced expression of UBE3A and GABRB3. Hum. Mol. Genet., 14, 483-492.
-
(2005)
Hum. Mol. Genet.
, vol.14
, pp. 483-492
-
-
Samaco, R.C.1
Hogart, A.2
LaSalle, J.M.3
-
13
-
-
77952317326
-
Partial silencing of methyl cytosine protein binding 2 (MECP2) in mesenchymal stem cells induces senescence with an increase in damaged DNA
-
Squillaro, T., Alessio, N., Cipollaro, M., Renieri, A., Giordano, A. and Galderisi, U. (2010) Partial silencing of methyl cytosine protein binding 2 (MECP2) in mesenchymal stem cells induces senescence with an increase in damaged DNA. FASEB J., 24, 1593-1603.
-
(2010)
FASEB J.
, vol.24
, pp. 1593-1603
-
-
Squillaro, T.1
Alessio, N.2
Cipollaro, M.3
Renieri, A.4
Giordano, A.5
Galderisi, U.6
-
14
-
-
0035504192
-
Methyl-CpG-binding protein 2 represses LINE-1 expression and retrotransposition but not Alu transcription
-
Yu, F., Zingler, N., Schumann, G. and Strätling, W.H. (2001) Methyl-CpG-binding protein 2 represses LINE-1 expression and retrotransposition but not Alu transcription. Nucleic Acids Res., 29, 4493-4501.
-
(2001)
Nucleic Acids Res.
, vol.29
, pp. 4493-4501
-
-
Yu, F.1
Zingler, N.2
Schumann, G.3
Strätling, W.H.4
-
15
-
-
78549247463
-
L1 retrotransposition in neurons is modulated by MeCP2
-
Muotri, A.R., Marchetto, M.C., Coufal, N.G., Oefner, R., Yeo, G., Nakashima, K. and Gage, F.H. (2010) L1 retrotransposition in neurons is modulated by MeCP2. Nature, 468, 443-446.
-
(2010)
Nature
, vol.468
, pp. 443-446
-
-
Muotri, A.R.1
Marchetto, M.C.2
Coufal, N.G.3
Oefner, R.4
Yeo, G.5
Nakashima, K.6
Gage, F.H.7
-
16
-
-
79960484375
-
Gene silencing in X-chromosome inactivation: advances in understanding facultative heterochromatin formation
-
Wutz, A. (2011) Gene silencing in X-chromosome inactivation: advances in understanding facultative heterochromatin formation. Nat. Rev. Genet., 12, 542-553.
-
(2011)
Nat. Rev. Genet.
, vol.12
, pp. 542-553
-
-
Wutz, A.1
-
17
-
-
42449134974
-
X-chromosome inactivation and epigenetic fluidity in human embryonic stem cells
-
Silva, S.S., Rowntree, R.K., Mekhoubad, S. and Lee, J.T. (2008) X-chromosome inactivation and epigenetic fluidity in human embryonic stem cells. Proc. Natl Acad. Sci. USA, 105, 4820-4825.
-
(2008)
Proc. Natl Acad. Sci. USA
, vol.105
, pp. 4820-4825
-
-
Silva, S.S.1
Rowntree, R.K.2
Mekhoubad, S.3
Lee, J.T.4
-
18
-
-
80052155858
-
Neuronal maturation defect in induced pluripotent stem cells from patients with Rett syndrome
-
Kim, K.Y., Hysolli, E. and Park, I.H. (2011) Neuronal maturation defect in induced pluripotent stem cells from patients with Rett syndrome. Proc. Natl Acad. Sci. USA, 108, 14169-14174.
-
(2011)
Proc. Natl Acad. Sci. USA
, vol.108
, pp. 14169-14174
-
-
Kim, K.Y.1
Hysolli, E.2
Park, I.H.3
-
19
-
-
84863615190
-
Derivation conditions impact X-inactivation status in femalehumaninduced pluripotent stem cells
-
Tomoda, K., Takahashi, K., Leung, K., Okada, A., Narita, M., Yamada, N.A., Eilertson, K.E., Tsang, P., Baba, S., White, M.P. et al. (2012) Derivation conditions impact X-inactivation status in femalehumaninduced pluripotent stem cells. Cell Stem Cell, 11, 91-99.
-
(2012)
Cell Stem Cell
, vol.11
, pp. 91-99
-
-
Tomoda, K.1
Takahashi, K.2
Leung, K.3
Okada, A.4
Narita, M.5
Yamada, N.A.6
Eilertson, K.E.7
Tsang, P.8
Baba, S.9
White, M.P.10
-
20
-
-
84860640679
-
Erosion of dosage compensation impacts human iPSC disease modeling
-
Mekhoubad, S., Bock, C., de Boer, A.S., Kiskinis, E., Meissner, A. and Eggan, K. (2012) Erosion of dosage compensation impacts human iPSC disease modeling. Cell Stem Cell, 10, 595-609.
-
(2012)
Cell Stem Cell
, vol.10
, pp. 595-609
-
-
Mekhoubad, S.1
Bock, C.2
de Boer, A.S.3
Kiskinis, E.4
Meissner, A.5
Eggan, K.6
-
21
-
-
77952732489
-
Derivation of pre-X inactivation human embryonic stem cells under physiological oxygen concentrations
-
Lengner, C.J., Gimelbrant, A.A., Erwin, J.A., Cheng, A.W., Guenther, M.G., Welstead, G.G., Alagappan, R., Frampton, G.M., Xu, P., Muffat, J. et al. (2010) Derivation of pre-X inactivation human embryonic stem cells under physiological oxygen concentrations. Cell, 141, 872-883.
-
(2010)
Cell
, vol.141
, pp. 872-883
-
-
Lengner, C.J.1
Gimelbrant, A.A.2
Erwin, J.A.3
Cheng, A.W.4
Guenther, M.G.5
Welstead, G.G.6
Alagappan, R.7
Frampton, G.M.8
Xu, P.9
Muffat, J.10
-
22
-
-
70450285340
-
Technical challenges in using human induced pluripotent stem cells to model disease
-
Saha, K. and Jaenisch, R. (2009) Technical challenges in using human induced pluripotent stem cells to model disease. Cell Stem Cell, 5, 584-595.
-
(2009)
Cell Stem Cell
, vol.5
, pp. 584-595
-
-
Saha, K.1
Jaenisch, R.2
-
23
-
-
38049187707
-
Reprogramming of human somatic cells to pluripotency with defined factors
-
Park, I.H., Zhao, R., West, J.A., Yabuuchi, A., Huo, H., Ince, T.A., Lerou, P.H., Lensch, M.W. and Daley, G.Q. (2008) Reprogramming of human somatic cells to pluripotency with defined factors. Nature, 451, 141-146.
-
(2008)
Nature
, vol.451
, pp. 141-146
-
-
Park, I.H.1
Zhao, R.2
West, J.A.3
Yabuuchi, A.4
Huo, H.5
Ince, T.A.6
Lerou, P.H.7
Lensch, M.W.8
Daley, G.Q.9
-
24
-
-
33747195353
-
Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors
-
Takahashi, K. and Yamanaka, S. (2006) Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors. Cell, 126, 663-676.
-
(2006)
Cell
, vol.126
, pp. 663-676
-
-
Takahashi, K.1
Yamanaka, S.2
-
25
-
-
50549089957
-
Disease-specific induced pluripotent stem cells
-
Park, I.H., Arora, N., Huo, H., Maherali, N., Ahfeldt, T., Shimamura, A., Lensch, M.W., Cowan, C., Hochedlinger, K. and Daley, G.Q. (2008) Disease-specific induced pluripotent stem cells. Cell, 134, 877-886.
-
(2008)
Cell
, vol.134
, pp. 877-886
-
-
Park, I.H.1
Arora, N.2
Huo, H.3
Maherali, N.4
Ahfeldt, T.5
Shimamura, A.6
Lensch, M.W.7
Cowan, C.8
Hochedlinger, K.9
Daley, G.Q.10
-
26
-
-
84862822079
-
Human induced pluripotent stem cells and neurodegenerative disease: prospects for novel therapies
-
Jung, Y.W., Hysolli, E., Kim, K.Y., Tanaka, Y. and Park, I.H. (2012) Human induced pluripotent stem cells and neurodegenerative disease: prospects for novel therapies. Curr. Opin. Neurol., 25, 125-130.
-
(2012)
Curr. Opin. Neurol.
, vol.25
, pp. 125-130
-
-
Jung, Y.W.1
Hysolli, E.2
Kim, K.Y.3
Tanaka, Y.4
Park, I.H.5
-
27
-
-
79955602167
-
Isolation of MECP2-null Rett Syndrome patient hiPS cells and isogenic controls through X-chromosome inactivation
-
Cheung, A.Y., Horvath, L.M., Grafodatskaya, D., Pasceri, P., Weksberg, R., Hotta, A., Carrel, L. and Ellis, J. (2011) Isolation of MECP2-null Rett Syndrome patient hiPS cells and isogenic controls through X-chromosome inactivation. Hum. Mol. Genet., 20, 2103-2115.
-
(2011)
Hum. Mol. Genet.
, vol.20
, pp. 2103-2115
-
-
Cheung, A.Y.1
Horvath, L.M.2
Grafodatskaya, D.3
Pasceri, P.4
Weksberg, R.5
Hotta, A.6
Carrel, L.7
Ellis, J.8
-
28
-
-
79961133928
-
Unexpected X chromosome skewing during culture and reprogramming of human somatic cells can be alleviated by exogenous telomerase
-
Pomp, O., Dreesen, O., Leong, D.F., Meller-Pomp, O., Tan, T.T., Zhou, F. and Colman, A. (2011) Unexpected X chromosome skewing during culture and reprogramming of human somatic cells can be alleviated by exogenous telomerase. Cell Stem Cell, 9, 156-165.
-
(2011)
Cell Stem Cell
, vol.9
, pp. 156-165
-
-
Pomp, O.1
Dreesen, O.2
Leong, D.F.3
Meller-Pomp, O.4
Tan, T.T.5
Zhou, F.6
Colman, A.7
-
29
-
-
78149488365
-
Amodel for neural development and treatment of Rett syndrome using human induced pluripotent stem cells
-
Marchetto, M.C., Carromeu, C., Acab, A., Yu, D., Yeo, G.W., Mu, Y., Chen, G., Gage, F.H. and Muotri, A.R. (2010)Amodel for neural development and treatment of Rett syndrome using human induced pluripotent stem cells. Cell, 143, 527-539.
-
(2010)
Cell
, vol.143
, pp. 527-539
-
-
Marchetto, M.C.1
Carromeu, C.2
Acab, A.3
Yu, D.4
Yeo, G.W.5
Mu, Y.6
Chen, G.7
Gage, F.H.8
Muotri, A.R.9
-
30
-
-
65549144456
-
Rett syndrome astrocytes are abnormal and spread MeCP2 deficiency through gap junctions
-
Maezawa, I., Swanberg, S., Harvey, D., LaSalle, J.M. and Jin, L.W. (2009) Rett syndrome astrocytes are abnormal and spread MeCP2 deficiency through gap junctions. J. Neurosci., 29, 5051-5061.
-
(2009)
J. Neurosci.
, vol.29
, pp. 5051-5061
-
-
Maezawa, I.1
Swanberg, S.2
Harvey, D.3
LaSalle, J.M.4
Jin, L.W.5
-
31
-
-
84859454582
-
Wild-type microglia arrest pathology in a mouse model of Rett syndrome
-
Derecki, N.C., Cronk, J.C., Lu, Z., Xu, E., Abbott, S.B., Guyenet, P.G. and Kipnis, J. (2012) Wild-type microglia arrest pathology in a mouse model of Rett syndrome. Nature, 484, 105-109.
-
(2012)
Nature
, vol.484
, pp. 105-109
-
-
Derecki, N.C.1
Cronk, J.C.2
Lu, Z.3
Xu, E.4
Abbott, S.B.5
Guyenet, P.G.6
Kipnis, J.7
-
32
-
-
0242668706
-
Role of histone H3 lysine 27 methylation in X inactivation
-
Plath, K., Fang, J., Mlynarczyk-Evans, S.K., Cao, R., Worringer, K.A., Wang, H., de la Cruz, C.C., Otte, A.P., Panning, B. and Zhang, Y. (2003) Role of histone H3 lysine 27 methylation in X inactivation. Science, 300, 131-135.
-
(2003)
Science
, vol.300
, pp. 131-135
-
-
Plath, K.1
Fang, J.2
Mlynarczyk-Evans, S.K.3
Cao, R.4
Worringer, K.A.5
Wang, H.6
de la Cruz, C.C.7
Otte, A.P.8
Panning, B.9
Zhang, Y.10
-
33
-
-
79952264847
-
Hotspots of aberrant epigenomic reprogramming in human induced pluripotent stem cells
-
Lister, R., Pelizzola, M., Kida, Y.S., Hawkins, R.D., Nery, J.R., Hon, G., Antosiewicz-Bourget, J., O'Malley, R., Castanon, R., Klugman, S. et al. (2011) Hotspots of aberrant epigenomic reprogramming in human induced pluripotent stem cells. Nature, 471, 68-73.
-
(2011)
Nature
, vol.471
, pp. 68-73
-
-
Lister, R.1
Pelizzola, M.2
Kida, Y.S.3
Hawkins, R.D.4
Nery, J.R.5
Hon, G.6
Antosiewicz-Bourget, J.7
O'Malley, R.8
Castanon, R.9
Klugman, S.10
-
34
-
-
33745479882
-
Gene expression analysis exposes mitochondrial abnormalities in a mouse model of Rett syndrome
-
Kriaucionis, S., Paterson, A., Curtis, J., Guy, J., Macleod, N. and Bird, A. (2006) Gene expression analysis exposes mitochondrial abnormalities in a mouse model of Rett syndrome. Mol. Cell Biol., 26, 5033-5042.
-
(2006)
Mol. Cell Biol.
, vol.26
, pp. 5033-5042
-
-
Kriaucionis, S.1
Paterson, A.2
Curtis, J.3
Guy, J.4
Macleod, N.5
Bird, A.6
-
35
-
-
34247170462
-
FXYD1 Is an MeCP2 target gene overexpressed in the brains of rett syndrome patients and Mecp2-null mice
-
Deng, V., Matagne, V., Banine, F., Frerking, M., Ohliger, P., Budden, S., Pevsner, J., Dissen, G.A., Sherman, L.S. and Ojeda, S.R. (2007) FXYD1 Is an MeCP2 target gene overexpressed in the brains of rett syndrome patients and Mecp2-null mice. Hum. Mol. Genet., 16, 640-650.
-
(2007)
Hum. Mol. Genet.
, vol.16
, pp. 640-650
-
-
Deng, V.1
Matagne, V.2
Banine, F.3
Frerking, M.4
Ohliger, P.5
Budden, S.6
Pevsner, J.7
Dissen, G.A.8
Sherman, L.S.9
Ojeda, S.R.10
-
36
-
-
15244363491
-
The DNA sequence of the human X chromosome
-
Ross, M.T., Grafham, D.V., Coffey, A.J., Scherer, S., McLay, K., Muzny,D., Platzer, M., Howell, G.R., Burrows, C., Bird, C.P. et al. (2005) The DNA sequence of the human X chromosome. Nature, 434, 325-337.
-
(2005)
Nature
, vol.434
, pp. 325-337
-
-
Ross, M.T.1
Grafham, D.V.2
Coffey, A.J.3
Scherer, S.4
McLay, K.5
Muzny, D.6
Platzer, M.7
Howell, G.R.8
Burrows, C.9
Bird, C.P.10
-
37
-
-
84878591266
-
Subtelomeric hotspots of aberrant 5-hydroxymethylcytosine-mediated epigenetic modifications during reprogramming to pluripotency
-
Wang, T., Wu, H., Li, Y., Szulwach, K.E., Lin, L., Li, X., Chen, I.P., Goldlust, I.S., Chamberlain, S.J., Dodd, A. et al. (2013) Subtelomeric hotspots of aberrant 5-hydroxymethylcytosine-mediated epigenetic modifications during reprogramming to pluripotency. Nat. Cell Biol., 15, 700-711.
-
(2013)
Nat. Cell Biol.
, vol.15
, pp. 700-711
-
-
Wang, T.1
Wu, H.2
Li, Y.3
Szulwach, K.E.4
Lin, L.5
Li, X.6
Chen, I.P.7
Goldlust, I.S.8
Chamberlain, S.J.9
Dodd, A.10
-
38
-
-
15244353967
-
X-inactivation profile reveals extensive variability in X-linked gene expression in females
-
Carrel, L. and Willard, H.F. (2005) X-inactivation profile reveals extensive variability in X-linked gene expression in females. Nature, 434, 400-404.
-
(2005)
Nature
, vol.434
, pp. 400-404
-
-
Carrel, L.1
Willard, H.F.2
-
39
-
-
42249095974
-
Specific mutations in methyl-CpG-bindingprotein 2 confer different severity in Rett syndrome
-
Neul, J.L., Fang, P., Barrish, J., Lane, J., Caeg, E.B., Smith, E.O., Zoghbi, H., Percy, A. and Glaze, D.G. (2008) Specific mutations in methyl-CpG-bindingprotein 2 confer different severity in Rett syndrome. Neurology, 70, 1313-1321.
-
(2008)
Neurology
, vol.70
, pp. 1313-1321
-
-
Neul, J.L.1
Fang, P.2
Barrish, J.3
Lane, J.4
Caeg, E.B.5
Smith, E.O.6
Zoghbi, H.7
Percy, A.8
Glaze, D.G.9
-
40
-
-
84871563384
-
MeCP2 binds to 5hmC enriched within active genes and accessible chromatin in the nervous system
-
Mellén, M., Ayata, P., Dewell, S., Kriaucionis, S. and Heintz, N. (2012) MeCP2 binds to 5hmC enriched within active genes and accessible chromatin in the nervous system. Cell, 151, 1417-1430.
-
(2012)
Cell
, vol.151
, pp. 1417-1430
-
-
Mellén, M.1
Ayata, P.2
Dewell, S.3
Kriaucionis, S.4
Heintz, N.5
-
41
-
-
79959859654
-
Integrating 5-hydroxymethylcytosine into the epigenomic landscape of human embryonic stem cells
-
Szulwach, K.E., Li, X., Li, Y., Song, C.X., Han, J.W., Kim, S., Namburi, S., Hermetz, K., Kim, J.J., Rudd, M.K. et al. (2011) Integrating 5-hydroxymethylcytosine into the epigenomic landscape of human embryonic stem cells. PLoS Genet., 7, e1002154.
-
(2011)
PLoS Genet.
, vol.7
-
-
Szulwach, K.E.1
Li, X.2
Li, Y.3
Song, C.X.4
Han, J.W.5
Kim, S.6
Namburi, S.7
Hermetz, K.8
Kim, J.J.9
Rudd, M.K.10
-
42
-
-
82255192294
-
5-hmC-mediated Epigenetic dynamics during postnatal neurodevelopment, aging
-
Szulwach, K.E., Li, X., Li, Y., Song, C.X., Wu, H., Dai, Q., Irier, H., Upadhyay, A.K., Gearing, M., Levey, A.I. et al. (2011) 5-hmC-mediated Epigenetic dynamics during postnatal neurodevelopment and aging. Nat. Neurosci., 14, 1607-1616.
-
(2011)
Nat. Neurosci.
, vol.14
, pp. 1607-1616
-
-
Szulwach, K.E.1
Li, X.2
Li, Y.3
Song, C.X.4
Wu, H.5
Dai, Q.6
Irier, H.7
Upadhyay, A.K.8
Gearing, M.9
Levey, A.I.10
-
43
-
-
33749590330
-
Brain-specific phosphorylation of MeCP2 regulates activity-dependent Bdnf transcription, dendritic growth, and spine maturation
-
Zhou, Z., Hong, E.J., Cohen, S., Zhao, W.N., Ho, H.Y., Schmidt, L., Chen, W.G., Lin, Y., Savner, E., Griffith, E.C. et al. (2006) Brain-specific phosphorylation of MeCP2 regulates activity-dependent Bdnf transcription, dendritic growth, and spine maturation. Neuron, 52, 255-269.
-
(2006)
Neuron
, vol.52
, pp. 255-269
-
-
Zhou, Z.1
Hong, E.J.2
Cohen, S.3
Zhao, W.N.4
Ho, H.Y.5
Schmidt, L.6
Chen, W.G.7
Lin, Y.8
Savner, E.9
Griffith, E.C.10
-
44
-
-
52949111357
-
Genetic modifiers of MeCP2 function in Drosophila
-
Cukier, H.N., Perez, A.M., Collins, A.L., Zhou, Z., Zoghbi, H.Y. and Botas, J. (2008) Genetic modifiers of MeCP2 function in Drosophila. PLoS Genet., 4, e1000179.
-
(2008)
PLoS Genet.
, vol.4
-
-
Cukier, H.N.1
Perez, A.M.2
Collins, A.L.3
Zhou, Z.4
Zoghbi, H.Y.5
Botas, J.6
-
45
-
-
63849239275
-
Phosphorylation of MeCP2 at Serine 80 regulates its chromatin association and neurological function
-
Tao, J., Hu, K., Chang, Q., Wu, H., Sherman, N.E., Martinowich, K., Klose, R.J., Schanen, C., Jaenisch, R., Wang, W. et al. (2009) Phosphorylation of MeCP2 at Serine 80 regulates its chromatin association and neurological function. Proc. Natl Acad. Sci. USA, 106, 4882-4887.
-
(2009)
Proc. Natl Acad. Sci. USA
, vol.106
, pp. 4882-4887
-
-
Tao, J.1
Hu, K.2
Chang, Q.3
Wu, H.4
Sherman, N.E.5
Martinowich, K.6
Klose, R.J.7
Schanen, C.8
Jaenisch, R.9
Wang, W.10
-
46
-
-
84864150600
-
Mitochondrial dysfunction in Parkinson's disease: molecular mechanisms and pathophysiological consequences
-
Exner, N., Lutz, A.K., Haass, C. and Winklhofer, K.F. (2012) Mitochondrial dysfunction in Parkinson's disease: molecular mechanisms and pathophysiological consequences. EMBO J., 31, 3038-3062.
-
(2012)
EMBO J.
, vol.31
, pp. 3038-3062
-
-
Exner, N.1
Lutz, A.K.2
Haass, C.3
Winklhofer, K.F.4
-
47
-
-
70349422148
-
Role of mitochondrial dysfunction in the pathogenesis of Huntington's disease
-
Quintanilla, R.A. and Johnson, G.V. (2009) Role of mitochondrial dysfunction in the pathogenesis of Huntington's disease. Brain Res. Bull., 80, 242-247.
-
(2009)
Brain Res. Bull.
, vol.80
, pp. 242-247
-
-
Quintanilla, R.A.1
Johnson, G.V.2
-
48
-
-
50249098740
-
Generation of human-induced pluripotent stem cells
-
Park, I.H., Lerou, P.H., Zhao, R., Huo, H. and Daley, G.Q. (2008) Generation of human-induced pluripotent stem cells. Nat. Protoc., 3, 1180-1186.
-
(2008)
Nat. Protoc.
, vol.3
, pp. 1180-1186
-
-
Park, I.H.1
Lerou, P.H.2
Zhao, R.3
Huo, H.4
Daley, G.Q.5
-
49
-
-
77956222202
-
Female human iPSCs retain an inactive X chromosome
-
Tchieu, J., Kuoy, E., Chin, M.H., Trinh, H., Patterson, M., Sherman, S.P., Aimiuwu, O., Lindgren, A., Hakimian, S., Zack, J.A. et al. (2010) Female human iPSCs retain an inactive X chromosome. Cell Stem Cell, 7, 329-342.
-
(2010)
Cell Stem Cell
, vol.7
, pp. 329-342
-
-
Tchieu, J.1
Kuoy, E.2
Chin, M.H.3
Trinh, H.4
Patterson, M.5
Sherman, S.P.6
Aimiuwu, O.7
Lindgren, A.8
Hakimian, S.9
Zack, J.A.10
-
50
-
-
0030034051
-
XIST RNA paints the inactive X chromosome at interphase: evidence for a novel RNA involved in nuclear/chromosome structure
-
Clemson, C.M., McNeil, J.A., Willard, H.F. and Lawrence, J.B. (1996)XIST RNA paints the inactive X chromosome at interphase: evidence for a novel RNA involved in nuclear/chromosome structure. J. Cell Biol., 132, 259-275.
-
(1996)
J. Cell Biol.
, vol.132
, pp. 259-275
-
-
Clemson, C.M.1
McNeil, J.A.2
Willard, H.F.3
Lawrence, J.B.4
-
51
-
-
65449136284
-
Tophat: discovering splice junctions with RNA-Seq
-
Trapnell, C., Pachter, L. and Salzberg, S.L. (2009) Tophat: discovering splice junctions with RNA-Seq. Bioinformatics, 25, 1105-1111.
-
(2009)
Bioinformatics
, vol.25
, pp. 1105-1111
-
-
Trapnell, C.1
Pachter, L.2
Salzberg, S.L.3
-
52
-
-
77952123055
-
Transcript assembly and quantification by RNA-Seq reveals unannotated transcripts and isoform switching during cell differentiation
-
Trapnell, C., Williams, B.A., Pertea, G., Mortazavi, A., Kwan, G., van Baren, M.J., Salzberg, S.L., Wold, B.J. and Pachter, L. (2010) Transcript assembly and quantification by RNA-Seq reveals unannotated transcripts and isoform switching during cell differentiation. Nat. Biotechnol., 28, 511-515.
-
(2010)
Nat. Biotechnol.
, vol.28
, pp. 511-515
-
-
Trapnell, C.1
Williams, B.A.2
Pertea, G.3
Mortazavi, A.4
Kwan, G.5
van Baren, M.J.6
Salzberg, S.L.7
Wold, B.J.8
Pachter, L.9
|