Polarity and proliferation are controlled by distinct signaling pathways downstream of PI3-kinase in breast epithelial tumor cells

Journal of Cell Biology

Volumn 164, Issue 4, 2004, Pages 603-612

  Liu, Hong ^a   Radisky, Derek C ^a   Wang, Fei ^a,b   Bissell, Mina J ^a  

^a LAWRENCE BERKELEY NATIONAL LABORATORY   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Akt; Rac1; Three dimensional cultures; Tissue polarity; Tumor reversion

Indexed keywords

2 MORPHOLINO 8 PHENYLCHROMONE; BETA1 INTEGRIN; EPIDERMAL GROWTH FACTOR RECEPTOR; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 3 KINASE INHIBITOR; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PHOSPHOLIPID; PROTEIN KINASE B; RAC1 PROTEIN; WORTMANNIN;

ANCHORAGE INDEPENDENT GROWTH; APOPTOSIS; ARTICLE; BREAST EPITHELIUM; BREAST TUMOR; CELL POLARITY; CELL PROLIFERATION; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME INHIBITION; HUMAN; HUMAN CELL; PHENOTYPE; PRIORITY JOURNAL; REVERTANT;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ACTINS; ANIMALS; BREAST NEOPLASMS; CELL CULTURE TECHNIQUES; CELL DIVISION; CELL POLARITY; CHROMONES; DOWN-REGULATION; ENZYME INHIBITORS; EPITHELIAL CELLS; FEMALE; HUMANS; INTEGRIN ALPHA6; MEMBRANE PROTEINS; MORPHOLINES; NEOPLASMS, GLANDULAR AND EPITHELIAL; PHENOTYPE; PHOSPHOLIPIDS; PHOSPHOPROTEINS; PROTEIN-SERINE-THREONINE KINASES; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-AKT; RAC1 GTP-BINDING PROTEIN; SIGNAL TRANSDUCTION; TUMOR CELLS, CULTURED;

EID: 1242285135     PISSN: 00219525     EISSN: None     Source Type: Journal    
DOI: 10.1083/jcb.200306090     Document Type: Article

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