Novel Rap1 dominant-negative mutants interfere selectively with C3G and Epac

Oncogene

Volumn 24, Issue 28, 2005, Pages 4509-4520

  Dupuy, Aurélien G ^a   L'Hoste, Sébastien ^a   Cherfils, Jacqueline ^b   Camonis, Jacques ^a   Gaudriault, Georges ^a,c   De Gunzburg, Jean ^a  

^a INSTITUT CURIE   (France)

^b LABORATOIRE D ENZYMOLOGIE ET BIOCHIMIE STRUCTURALES   (France)

^c ObeTherapy Biotechnology   (France)

Author keywords

C3G; Dominant negative; Epac; GEF; Rap

Indexed keywords

C3G PROTEIN; EPAC PROTEIN; GENE PRODUCT; GUANINE NUCLEOTIDE EXCHANGE FACTOR; GUANOSINE TRIPHOSPHATASE; INTEGRIN; RAP PROTEIN; RAP1 PROTEIN; UNCLASSIFIED DRUG; UVOMORULIN;

ANIMAL CELL; ARTICLE; BINDING SITE; CONTROLLED STUDY; DROSOPHILA; GENE OVEREXPRESSION; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; MUTAGENESIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN FAMILY; PROTEIN PROTEIN INTERACTION; SIGNAL TRANSDUCTION;

AMINO ACID SEQUENCE; ANIMALS; ANIMALS, GENETICALLY MODIFIED; BASE SEQUENCE; BINDING SITES; CARRIER PROTEINS; CELLS, CULTURED; COMPLEMENT C3; COMPLEMENT C3B; CYCLIC AMP; DROSOPHILA MELANOGASTER; EYE ABNORMALITIES; GENES, DOMINANT; GENES, LETHAL; GUANINE NUCLEOTIDE EXCHANGE FACTORS; HUMANS; MOLECULAR SEQUENCE DATA; MUTATION; RAP1 GTP-BINDING PROTEINS; SIGNAL TRANSDUCTION;

EID: 22744433950     PISSN: 09509232     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.onc.1208647     Document Type: Article

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