Ethanol inhibits activation of NLRP3 and AIM2 inflammasomes in human macrophages - A novel anti-inflammatory action of alcohol

PLoS ONE

Volumn 8, Issue 11, 2013, Pages

  Nurmi, Katariina ^a   Virkanen, Juhani ^b   Rajamäki, Kristiina ^a   Niemi, Katri ^a   Kovanen, Petri T ^a   Eklund, Kari K ^a,c  

^a WIHURI RESEARCH INSTITUTE   (Finland)

^b UNIVERSITY OF HELSINKI   (Finland)

^c HELSINKI UNIVERSITY CENTRAL HOSPITAL   (Finland)

Author keywords

[No Author keywords available]

Indexed keywords

ACETALDEHYDE; AIM2; ALCOHOL; CASPASE 8; CATHEPSIN B; CHOLESTEROL; CRYOPYRIN; INFLAMMASOME; INTERLEUKIN 18; INTERLEUKIN 1BETA; INTERLEUKIN 1BETA CONVERTING ENZYME; SERUM AMYLOID A; TOLL LIKE RECEPTOR 2; TOLL LIKE RECEPTOR 4; UNCLASSIFIED DRUG;

ALCOHOL CONSUMPTION; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CELL DEATH; CRYSTALLIZATION; CYTOKINE PRODUCTION; CYTOKINE RELEASE; ENZYME ACTIVATION; ENZYME INHIBITION; ENZYME LINKED IMMUNOSORBENT ASSAY; HUMAN; ISCHEMIC HEART DISEASE; LYSOSOME; MACROPHAGE; OLIGOMERIZATION; QUANTITATIVE ANALYSIS; REAL TIME POLYMERASE CHAIN REACTION; WESTERN BLOTTING;

ALCOHOL DRINKING; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; CARRIER PROTEINS; CELL LINE, TUMOR; CENTRAL NERVOUS SYSTEM DEPRESSANTS; CORONARY DISEASE; ETHANOL; HUMANS; INFLAMMASOMES; INTERLEUKIN-1BETA; LIPOPOLYSACCHARIDES; MACROPHAGES; NUCLEAR PROTEINS;

EID: 84892904301     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0078537     Document Type: Article

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