Ethanol-mediated regulation of cytochrome P450 2A6 expression in monocytes: Role of oxidative stress-mediated PKC/MEK/Nrf2 pathway

PLoS ONE

Volumn 7, Issue 4, 2012, Pages

  Jin, Mengyao ^a   Kumar, Anil ^a   Kumar, Santosh ^a  

^a UNIVERSITY OF MISSOURI KANSAS CITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

1,4 DIAMINO 1,4 BIS(2 AMINOPHENYLTHIO) 2,3 DICYANOBUTADIENE; ALCOHOL; ALLYL SULFIDE; ASCORBIC ACID; BUTYLATED HYDROXYANISOLE; CYTOCHROME P450 2A6; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN KINASE C; REACTIVE OXYGEN METABOLITE; STAUROSPORINE; TRANSCRIPTION FACTOR NRF2;

ARTICLE; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; GENE EXPRESSION REGULATION; GENE TRANSLOCATION; HUMAN; HUMAN CELL; MONOCYTE; OXIDATIVE STRESS; PROTEIN EXPRESSION; PROTEIN INDUCTION; REGULATORY MECHANISM;

ACTIVE TRANSPORT, CELL NUCLEUS; ARYL HYDROCARBON HYDROXYLASES; ASCORBIC ACID; CYTOCHROME P-450 CYP2E1; ENZYME ACTIVATION; ETHANOL; HUMANS; MITOGEN-ACTIVATED PROTEIN KINASE KINASES; MODELS, BIOLOGICAL; MONOCYTES; NF-E2-RELATED FACTOR 2; OXIDATIVE STRESS; PROTEIN KINASE C; SIGNAL TRANSDUCTION; U937 CELLS;

EID: 84859958024     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0035505     Document Type: Article

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