Helicobacter pylori and autoimmune disease: Cause or bystander

World Journal of Gastroenterology

Volumn 20, Issue 3, 2014, Pages 613-629

  Smyk, Daniel S ^a   Koutsoumpas, Andreas L ^a,b   Mytilinaiou, Maria G ^a   Rigopoulou, Eirini I ^b   Sakkas, Lazaros I ^a,b   Bogdanos, Dimitrios P ^a,b,c  

^a KING S COLLEGE HOSPITAL   (United Kingdom)

^b UNIVERSITY OF THESSALY   (Greece)

^c INFORMATION TECHNOLOGIES INSTITUTE   (Greece)

Author keywords

Autoimmunity; Gastritis; Helicobacter pylori; Infection; Mimicry; Rheumatology

Indexed keywords

C REACTIVE PROTEIN; CAGA PROTEIN; IMMUNOGLOBULIN G ANTIBODY; IMMUNOGLOBULIN M ANTIBODY; NONSTEROID ANTIINFLAMMATORY AGENT;

ALOPECIA AREATA; ARTICLE; AUTOIMMUNE DISEASE; AUTOIMMUNE HEPATITIS; AUTOIMMUNE THYROIDITIS; BEHCET DISEASE; CHRONIC URTICARIA; DISEASE ASSOCIATION; HELICOBACTER INFECTION; HUMAN; IDIOPATHIC THROMBOCYTOPENIC PURPURA; MULTIPLE SCLEROSIS; MYELOOPTIC NEUROPATHY; POLYMERASE CHAIN REACTION; PRIMARY BILIARY CIRRHOSIS; PRIMARY SCLEROSING CHOLANGITIS; PSORIASIS; RHEUMATOID ARTHRITIS; SJOEGREN SYNDROME; SYSTEMIC LUPUS ERYTHEMATOSUS; VASCULITIS;

AUTOIMMUNITY; GASTRITIS; HELICOBACTER PYLORI; INFECTION; MIMICRY; RHEUMATOLOGY;

ANIMALS; ANTIBODIES, BACTERIAL; AUTOIMMUNE DISEASES; AUTOIMMUNITY; HELICOBACTER INFECTIONS; HELICOBACTER PYLORI; HUMANS; RISK ASSESSMENT; RISK FACTORS;

EID: 84892897853     PISSN: 10079327     EISSN: 22192840     Source Type: Journal    
DOI: 10.3748/wjg.v20.i3.613     Document Type: Article

References (159)

1. Smyk D, Rigopoulou EI, Baum H, Burroughs AK, Vergani D, Bogdanos DP. Autoimmunity and environment: am I at risk? Clin Rev Allergy Immunol 2012; 42: 199-212 [PMID: 21337133 DOI: 10.1007/s12016-011-8259-x]
2. Shoenfeld Y, Blank M, Abu-Shakra M, Amital H, Barzilai O, Berkun Y, Bizzaro N, Gilburd B, Zandman-Goddard G, Katz U, Krause I, Langevitz P, Mackay IR, Orbach H, Ram M, Sherer Y, Toubi E, Gershwin ME. The mosaic of autoimmunity: prediction, autoantibodies, and therapy in autoimmune diseases--2008. Isr Med Assoc J 2008; 10: 13-19 [PMID: 18300564]
3. Shoenfeld Y, Gilburd B, Abu-Shakra M, Amital H, Barzilai O, Berkun Y, Blank M, Zandman-Goddard G, Katz U, Krause I, Langevitz P, Levy Y, Orbach H, Pordeus V, Ram M, Sherer Y, Toubi E, Tomer Y. The mosaic of autoimmunity: genetic factors involved in autoimmune diseases--2008. Isr Med Assoc J 2008; 10: 3-7 [PMID: 18300562]
4. Shoenfeld Y, Zandman-Goddard G, Stojanovich L, Cutolo M, Amital H, Levy Y, Abu-Shakra M, Barzilai O, Berkun Y, Blank M, de Carvalho JF, Doria A, Gilburd B, Katz U, Krause I, Langevitz P, Orbach H, Pordeus V, Ram M, Toubi E, Sherer Y. The mosaic of autoimmunity: hormonal and environmental factors involved in autoimmune diseases--2008. Isr Med Assoc J 2008; 10: 8-12 [PMID: 18300563]
5. Bogdanos DP, Smyk DS, Invernizzi P, Rigopoulou EI, Blank M, Pouria S, Shoenfeld Y. Infectome: a platform to trace infectious triggers of autoimmunity. Autoimmun Rev 2013; 12: 726-740 [PMID: 23266520 DOI: 10.1016/j.autrev.2012.12.005]
6. Bach JF. Infections and autoimmune diseases. J Autoimmun 2005; 25 Suppl: 74-80 [PMID: 16278064 DOI: 10.1016/ j.jaut.2005.09.024]
7. Getts MT, Miller SD. 99th Dahlem conference on infection, inflammation and chronic inflammatory disorders: triggering of autoimmune diseases by infections. Clin Exp Immunol 2010; 160: 15-21 [PMID: 20415846 DOI: 10.1111/j.1365-2249.2010.04132.x]
8. Fujinami RS, von Herrath MG, Christen U, Whitton JL. Molecular mimicry, bystander activation, or viral persistence: infections and autoimmune disease. Clin Microbiol Rev 2006; 19: 80-94 [PMID: 16418524 DOI: 10.1128/CMR.19.1.80-94.2006]
9. Olson JK, Ercolini AM, Miller SD. A virus-induced molecular mimicry model of multiple sclerosis. Curr Top Microbiol Immunol 2005; 296: 39-53 [PMID: 16323419]
10. Vial T, Descotes J. Autoimmune diseases and vaccinations. Eur J Dermatol 2004; 14: 86-90 [PMID: 15196997]
11. McCoy L, Tsunoda I, Fujinami RS. Multiple sclerosis and virus induced immune responses: autoimmunity can be primed by molecular mimicry and augmented by bystander activation. Autoimmunity 2006; 39: 9-19 [PMID: 16455578 DOI: 10.1080/08916930500484799]
12. Röner S, Zinser E, Menges M, Wiethe C, Littmann L, Hänig J, Steinkasserer A, Lutz MB. Minor role of bystander tolerance to fetal calf serum in a peptide-specific dendritic cell vaccine model against autoimmunity: comparison with serum-free cultures. J Immunother 2008; 31: 656-664 [PMID: 18600179 DOI: 10.1097/CJI.0b013e31818283ef]
13. Ram M, Shoenfeld Y. Hepatitis B: infection, vaccination and autoimmunity. Isr Med Assoc J 2008; 10: 61-64 [PMID: 18300577]
14. Ravel G, Christ M, Horand F, Descotes J. Autoimmunity, environmental exposure and vaccination: is there a link? Toxicology 2004; 196: 211-216 [PMID: 15036747 DOI: 10.1016/ j.tox.2003.10.005]
15. Ram M, Barzilai O, Shapira Y, Anaya JM, Tincani A, Stojanovich L, Bombardieri S, Bizzaro N, Kivity S, Agmon Levin N, Shoenfeld Y. Helicobacter pylori serology in autoimmune diseases-fact or fiction? Clin Chem Lab Med 2013; 51: 1075-1082 [PMID: 23079514 DOI: 10.1515/cclm-2012-0477]
16. Erdoǧan A, Yilmaz U. Is there a relationship between Helicobacter pylori and gastric autoimmunity? Turk J Gastroenterol 2011; 22: 134-138 [PMID: 21796548]
17. Veijola LI, Oksanen AM, Sipponen PI, Rautelin HI. Association of autoimmune type atrophic corpus gastritis with Helicobacter pylori infection. World J Gastroenterol 2010; 16: 83-88 [PMID: 20039453]
18. Oksanen AM, Haimila KE, Rautelin HI, Partanen JA. Immunogenetic characteristics of patients with autoimmune gastritis. World J Gastroenterol 2010; 16: 354-358 [PMID: 20082482]
19. Hasni S, Ippolito A, Illei GG. Helicobacter pylori and autoimmune diseases. Oral Dis 2011; 17: 621-627 [PMID: 21902767 DOI: 10.1111/j.1601-0825.2011.01796.x]
20. Jackson L, Britton J, Lewis SA, McKeever TM, Atherton J, Fullerton D, Fogarty AW. A population-based epidemiologic study of Helicobacter pylori infection and its association with systemic inflammation. Helicobacter 2009; 14: 108-113 [PMID: 19751435 DOI: 10.1111/j.1523-5378.2009.00711.x]
21. Amedei A, Bergman MP, Appelmelk BJ, Azzurri A, Benagiano M, Tamburini C, van der Zee R, Telford JL, Vandenbroucke-Grauls CM, D'Elios MM, Del Prete G. Molecular mimicry between Helicobacter pylori antigens and H+, K+--adenosine triphosphatase in human gastric autoimmunity. J Exp Med 2003; 198: 1147-1156 [PMID: 14568977 DOI: 10.1084/jem.20030530]
22. Yamanishi S, Iizumi T, Watanabe E, Shimizu M, Kamiya S, Nagata K, Kumagai Y, Fukunaga Y, Takahashi H. Implications for induction of autoimmunity via activation of B-1 cells by Helicobacter pylori urease. Infect Immun 2006; 74: 248-256 [PMID: 16368978 DOI: 10.1128/IAI.74.1.248-256.2006]
23. Aragona P, Magazzù G, Macchia G, Bartolone S, Di Pasquale G, Vitali C, Ferreri G. Presence of antibodies against Helicobacter pylori and its heat-shock protein 60 in the serum of patients with Sjögren's syndrome. J Rheumatol 1999; 26: 1306-1311 [PMID: 10381048]
24. Goo MJ, Ki MR, Lee HR, Hong IH, Park JK, Yang HJ, Yuan DW, Hwang OK, Do SH, Yoo SE, Jeong KS. Primary biliary cirrhosis, similar to that in human beings, in a male C57BL/6 mouse infected with Helicobacter pylori. Eur J Gastroenterol Hepatol 2008; 20: 1045-1048 [PMID: 18787477 DOI: 10.1097/MEG.0b013e3282f5e9db]
25. Bürgers R, Schneider-Brachert W, Reischl U, Behr A, Hiller KA, Lehn N, Schmalz G, Ruhl S. Helicobacter pylori in human oral cavity and stomach. Eur J Oral Sci 2008; 116: 297-304 [PMID: 18705796 DOI: 10.1111/j.1600-0722.2008.00543.x]
26. El Miedany YM, Baddour M, Ahmed I, Fahmy H. Sjogren's syndrome: concomitant H. pylori infection and possible correlation with clinical parameters. Joint Bone Spine 2005; 72: 135-141 [PMID: 15797493 DOI: 10.1016/j.jbspin.2004.04.005]
27. Showji Y, Nozawa R, Sato K, Suzuki H. Seroprevalence of Helicobacter pylori infection in patients with connective tissue diseases. Microbiol Immunol 1996; 40: 499-503 [PMID: 8865155]
28. Theander E, Nilsson I, Manthorpe R, Jacobsson LT, Wadström T. Seroprevalence of Helicobacter pylori in primary Sjögren's syndrome. Clin Exp Rheumatol 2001; 19: 633-638 [PMID: 11791633]
29. Royer B, Cazals-Hatem D, Sibilia J, Agbalika F, Cayuela JM, Soussi T, Maloisel F, Clauvel JP, Brouet JC, Mariette X. Lymphomas in patients with Sjogren's syndrome are marginal zone B-cell neoplasms, arise in diverse extranodal and nodal sites, and are not associated with viruses. Blood 1997; 90: 766-775 [PMID: 9226177]
30. Iwai H, Nakamichi N, Nakae K, Konishi M, Inaba M, Hoshino S, Baba S, Amakawa R. Parotid mucosa-associated lymphoid tissue lymphoma regression after Helicobacter pylori eradication. Laryngoscope 2009; 119: 1491-1494 [PMID: 19504556 DOI: 10.1002/lary.20258]
31. Parsonnet J, Hansen S, Rodriguez L, Gelb AB, Warnke RA, Jellum E, Orentreich N, Vogelman JH, Friedman GD. Helicobacter pylori infection and gastric lymphoma. N Engl J Med 1994; 330: 1267-1271 [PMID: 8145781 DOI: 10.1056/ NEJM199405053301803]
32. Suchy BH, Wolf SR. Bilateral mucosa-associated lymphoid tissue lymphoma of the parotid gland. Arch Otolaryngol Head Neck Surg 2000; 126: 224-226 [PMID: 10680876]
33. Janssen M, Dijkmans BA, van der Sluys FA, van der Wielen JG, Havenga K, Vandenbroucke JP, Lamers CB, Zwinderman AH, Cats A. Upper gastrointestinal complaints and complications in chronic rheumatic patients in comparison with other chronic diseases. Br J Rheumatol 1992; 31: 747-752 [PMID: 1450796]
34. Meron MK, Amital H, Shepshelovich D, Barzilai O, Ram M, Anaya JM, Gerli R, Nicola B, Shoenfeld Y. Infectious aspects and the etiopathogenesis of rheumatoid arthritis. Clin Rev Allergy Immunol 2010; 38: 287-291 [PMID: 19575154 DOI: 10.1007/ s12016-009-8158-6]
35. Tanaka E, Singh G, Saito A, Syouji A, Yamada T, Urano W, Nakajima A, Taniguchi A, Tomatsu T, Hara M, Saito T, Kamatani N, Yamanaka H. Prevalence of Helicobacter pylori infection and risk of upper gastrointestinal ulcer in patients with rheumatoid arthritis in Japan. Mod Rheumatol 2005; 15: 340-345 [PMID: 17029090 DOI: 10.1007/s10165-005-0419-5]
36. Ishikawa N, Fuchigami T, Matsumoto T, Kobayashi H, Sakai Y, Tabata H, Takubo N, Yamamoto S, Nakanishi M, Tomioka K, Fujishima M. Helicobacter pylori infection in rheumatoid arthritis: effect of drugs on prevalence and correlation with gastroduodenal lesions. Rheumatology (Oxford) 2002; 41: 72-77 [PMID: 11792883]
37. Matsukawa Y, Asai Y, Kitamura N, Sawada S, Kurosaka H. Exacerbation of rheumatoid arthritis following Helicobacter pylori eradication: disruption of established oral tolerance against heat shock protein? Med Hypotheses 2005; 64: 41-43 [PMID: 15533608 DOI: 10.1016/j.mehy.2004.06.021]
38. Steen KS, Lems WF, Visman IM, de Koning MH, van de Stadt RJ, Twisk JW, de Leest HT, Dijkmans BA, Nurmohamed MT. The effect of Helicobacter pylori eradication on C-reactive protein and the lipid profile in patients with rheumatoid arthritis using chronic NSAIDs. Clin Exp Rheumatol 2009; 27: 170 [PMID: 19327252]
39. Seriolo B, Cutolo M, Zentilin P, Savarino V. Helicobacter pylori infection in rheumatoid arthritis. J Rheumatol 2001; 28: 1195-1196 [PMID: 11361212]
40. Zentilin P, Seriolo B, Dulbecco P, Caratto E, Iiritano E, Fasciolo D, Bilardi C, Mansi C, Testa E, Savarino V. Eradication of Helicobacter pylori may reduce disease severity in rheumatoid arthritis. Aliment Pharmacol Ther 2002; 16: 1291-1299 [PMID: 12144579]
41. Shapira Y, Agmon-Levin N, Renaudineau Y, Porat-Katz BS, Barzilai O, Ram M, Youinou P, Shoenfeld Y. Serum markers of infections in patients with primary biliary cirrhosis: evidence of infection burden. Exp Mol Pathol 2012; 93: 386-390 [PMID: 23022373 DOI: 10.1016/j.yexmp.2012.09.012]
42. Kalabay L, Fekete B, Czirják L, Horváth L, Daha MR, Veres A, Fónyad G, Horváth A, Viczián A, Singh M, Hoffer I, Füst G, Romics L, Prohászka Z. Helicobacter pylori infection in connective tissue disorders is associated with high levels of antibodies to mycobacterial hsp65 but not to human hsp60. Helicobacter 2002; 7: 250-256 [PMID: 12165033 DOI: 10.1046/ j.1523-5378.2002.00092.x]
43. Sawalha AH, Schmid WR, Binder SR, Bacino DK, Harley JB. Association between systemic lupus erythematosus and Helicobacter pylori seronegativity. J Rheumatol 2004; 31: 1546-1550 [PMID: 15290733]
44. Matsukawa Y. Association between systemic lupus erythematosus and Helicobacter pylori. J Rheumatol 2005; 32: 965 [PMID: 15909376]
45. Sakkas LI, Chikanza IC, Platsoucas CD. Mechanisms of Disease: the role of immune cells in the pathogenesis of systemic sclerosis. Nat Clin Pract Rheumatol 2006; 2: 679-685 [PMID: 17133253 DOI: 10.1038/ncprheum0346]
46. Sakkas LI. New developments in the pathogenesis of systemic sclerosis. Autoimmunity 2005; 38: 113-116 [PMID: 16040330]
47. Sakkas LI, Xu B, Artlett CM, Lu S, Jimenez SA, Platsoucas CD. Oligoclonal T cell expansion in the skin of patients with systemic sclerosis. J Immunol 2002; 168: 3649-3659 [PMID: 11907131]
48. Bogdanos DP, Smyk DS, Rigopoulou EI, Mytilinaiou MG, Heneghan MA, Selmi C, Gershwin ME. Twin studies in autoimmune disease: genetics, gender and environment. J Autoimmun 2012; 38: J156-J169 [PMID: 22177232 DOI: 10.1016/ j.jaut.2011.11.003]
49. Yazawa N, Fujimoto M, Kikuchi K, Kubo M, Ihn H, Sato S, Tamaki T, Tamaki K. High seroprevalence of Helicobacter pylori infection in patients with systemic sclerosis: association with esophageal involvement. J Rheumatol 1998; 25: 650-653 [PMID: 9558164]
50. Yamaguchi K, Iwakiri R, Hara M, Kikkawa A, Fujise T, Ootani H, Shimoda R, Tsunada S, Sakata H, Ushiyama O, Koarada S, Tada Y, Nagasawa K, Fujimoto K. Reflux esophagitis and Helicobacter pylori infection in patients with scleroderma. Intern Med 2008; 47: 1555-1559 [PMID: 18797112]
51. Farina G, Rosato E, Francia C, Proietti M, Donato G, Ammendolea C, Pisarri S, Salsano F. High incidence of Helicobacter pylori infection in patients with systemic sclerosis: association with Sicca Syndrome. Int J Immunopathol Pharmacol 2001; 14: 81-85 [PMID: 12604022]
52. Kountouras J, Zavos C, Gavalas E, Deretzi G, Katsinelos P, Boura P, Polyzos SA, Venizelos I. Helicobacter pylori may be a common denominator associated with systemic and multiple sclerosis. Joint Bone Spine 2011; 78: 222-323; author reply 223 [PMID: 21345710]
53. Savarino V, Sulli A, Zentilin P, Raffaella Mele M, Cutolo M. No evidence of an association between Helicobacter pylori infection and Raynaud phenomenon. Scand J Gastroenterol 2000; 35: 1251-1254 [PMID: 11199362]
54. Sulli A, Seriolo B, Savarino V, Cutolo M. Lack of correlation between gastric Helicobacter pylori infection and primary or secondary Raynaud's phenomenon in patients with systemic sclerosis. J Rheumatol 2000; 27: 1820-1821 [PMID: 10914880]
55. Hervé F, Cailleux N, Benhamou Y, Ducrotté P, Lemeland JF, Denis P, Marie I, Lévesque H. [Helicobacter pylori prevalence in Raynaud's disease]. Rev Med Interne 2006; 27: 736-741 [PMID: 16978744]
56. Danese S, Zoli A, Cremonini F, Gasbarrini A. High prevalence of Helicobacter pylori type I virulent strains in patients with systemic sclerosis. J Rheumatol 2000; 27: 1568-1569 [PMID: 10852299]
57. Gasbarrini A, Massari I, Serricchio M, Tondi P, De Luca A, Franceschi F, Ojetti V, Dal Lago A, Flore R, Santoliquido A, Gasbarrini G, Pola P. Helicobacter pylori eradication ameliorates primary Raynaud's phenomenon. Dig Dis Sci 1998; 43: 1641-1645 [PMID: 9724144]
58. Csiki Z, Gál I, Sebesi J, Szegedi G. [Raynaud syndrome and eradication of Helicobacter pylori]. Orv Hetil 2000; 141: 2827-2829 [PMID: 11202119]
59. Radić M, Kaliterna DM, Bonacin D, Vergles JM, Radić J, Fabijanić D, Kovačić V. Is Helicobacter pylori infection a risk factor for disease severity in systemic sclerosis? Rheumatol Int 2013; 33: 2943-2948 [PMID: 23224499 DOI: 10.1007/s00296-012-2585-z]
60. Wipff J, Allanore Y, Soussi F, Terris B, Abitbol V, Raymond J, Chaussade S, Kahan A. Prevalence of Barrett's esophagus in systemic sclerosis. Arthritis Rheum 2005; 52: 2882-2888 [PMID: 16142744 DOI: 10.1002/art.21261]
61. Lidar M, Lipschitz N, Langevitz P, Barzilai O, Ram M, Porat-Katz BS, Pagnoux C, Guilpain P, Sinico RA, Radice A, Bizzaro N, Damoiseaux J, Tervaert JW, Martin J, Guillevin L, Bombardieri S, Shoenfeld Y. Infectious serologies and autoantibodies in Wegener's granulomatosis and other vasculitides: novel associations disclosed using the Rad BioPlex 2200. Ann N Y Acad Sci 2009; 1173: 649-657 [PMID: 19758211]
62. Shen L, Matsunami Y, Quan N, Kobayashi K, Matsuura E, Oguma K. In vivo oxidation, platelet activation and simultaneous occurrence of natural immunity in atherosclerosis-prone mice. Isr Med Assoc J 2011; 13: 278-283 [PMID: 21845968]
63. Oshima T, Ozono R, Yano Y, Oishi Y, Teragawa H, Higashi Y, Yoshizumi M, Kambe M. Association of Helicobacter pylori infection with systemic inflammation and endothelial dysfunction in healthy male subjects. J Am Coll Cardiol 2005; 45: 1219-1222 [PMID: 15837252]
64. Zycinska K, Wardyn KA, Zycinski Z, Smolarczyk R. Correlation between Helicobacter pylori infection and pulmonary Wegener's granulomacytosis activity. J Physiol Pharmacol 2008; 59 Suppl 6: 845-851 [PMID: 19218713]
65. Cicconi V, Carloni E, Franceschi F, Nocente R, Silveri NG, Manna R, Servidei S, Bentivoglio AR, Gasbarrini A, Gasbarrini G. Disappearance of antiphospholipid antibodies syndrome after Helicobacter pylori eradication. Am J Med 2001; 111: 163-164 [PMID: 11501549]
66. Hernando-harder AC, Booken N, Goerdt S, Singer MV, Harder H. Helicobacter pylori infection and dermatologic diseases. Eur J Dermatol 2009; 19: 431-444 [PMID: 19527988]
67. Halasz CL. Helicobacter pylori antibodies in patients with psoriasis. Arch Dermatol 1996; 132: 95-96 [PMID: 8546497]
68. Daudén E, Cabrera MM, Oñate MJ, Pajares JM, García-Díez A. CagA seropositivity in Helicobacter pylori positive patients with psoriasis. J Eur Acad Dermatol Venereol 2004; 18: 116-117 [PMID: 14678557]
69. Daudén E, Vázquez-Carrasco MA, Peñas PF, Pajares JM, García-Díez A. Association of Helicobacter pylori infection with psoriasis and lichen planus: prevalence and effect of eradication therapy. Arch Dermatol 2000; 136: 1275-1276 [PMID: 11030788]
70. Wedi B, Kapp A. Helicobacter pylori infection in skin diseases: a critical appraisal. Am J Clin Dermatol 2002; 3: 273-282 [PMID: 12010072]
71. Wedi B, Kapp A. Helicobacter pylori infection and skin diseases. J Physiol Pharmacol 1999; 50: 753-776 [PMID: 10695557]
72. Qayoom S, Ahmad QM. Psoriasis and Helicobacter pylori. Indian J Dermatol Venereol Leprol 2003; 69: 133-134 [PMID: 17642857]
73. Ali M, Whitehead M. Clearance of chronic psoriasis after eradication therapy for Helicobacter pylori infection. J Eur Acad Dermatol Venereol 2008; 22: 753-754 [PMID: 18005018]
74. Sáez-Rodríguez M, Noda-Cabrera A, García-Bustínduy M, Guimerá-Martín-Neda F, Dorta-Alom S, Escoda-García M, Fagundo-González E, Sánchez-González R, Rodríguez-García F, García-Montelongo R. Palmoplantar pustulosis associated with gastric Helicobacter pylori infection. Clin Exp Dermatol 2002; 27: 720 [PMID: 12472559]
75. Onsun N, Arda Ulusal H, Su O, Beycan I, Biyik Ozkaya D, Senocak M. Impact of Helicobacter pylori infection on severity of psoriasis and response to treatment. Eur J Dermatol 2012; 22: 117-120 [PMID: 22063790 DOI: 10.1684/ejd.2011.1579]
76. Martin Hübner A, Tenbaum SP. Complete remission of palmoplantar psoriasis through Helicobacter pylori eradication: a case report. Clin Exp Dermatol 2008; 33: 339-340 [PMID: 18201263]
77. Magen E, Mishal J. Possible benefit from treatment of Helicobacter pylori in antihistamine-resistant chronic urticaria. Clin Exp Dermatol 2013; 38: 7-12 [PMID: 23083221 DOI: 10.1111/j.1365-2230.2012.04467.x]
78. Magen E, Mishal J, Schlesinger M, Scharf S. Eradication of Helicobacter pylori infection equally improves chronic urticaria with positive and negative autologous serum skin test. Helicobacter 2007; 12: 567-571 [PMID: 17760727]
79. Magen E, Schlesinger M, Hadari I. Chronic urticaria can be triggered by eradication of Helicobacter pylori. Helicobacter 2013; 18: 83-87 [PMID: 23067254 DOI: 10.1111/hel.12010]
80. Shakouri A, Compalati E, Lang DM, Khan DA. Effectiveness of Helicobacter pylori eradication in chronic urticaria: evidence-based analysis using the Grading of Recommendations Assessment, Development, and Evaluation system. Curr Opin Allergy Clin Immunol 2010; 10: 362-369 [PMID: 20610979 DOI: 10.1097/ACI.0b013e32833c79d7]
81. Federman DG, Kirsner RS, Moriarty JP, Concato J. The effect of antibiotic therapy for patients infected with Helicobacter pylori who have chronic urticaria. J Am Acad Dermatol 2003; 49: 861-864 [PMID: 14576665 DOI: 10.1067/S0190]
82. Fukuda S, Shimoyama T, Umegaki N, Mikami T, Nakano H, Munakata A. Effect of Helicobacter pylori eradication in the treatment of Japanese patients with chronic idiopathic urticaria. J Gastroenterol 2004; 39: 827-830 [PMID: 15565400 DOI: 10.1007/s00535-004-1397-7]
83. Gaig P, García-Ortega P, Enrique E, Papo M, Quer JC, Richard C. Efficacy of the eradication of Helicobacter pylori infection in patients with chronic urticaria. A placebo-controlled double blind study. Allergol Immunopathol (Madr) 2002; 30: 255-258 [PMID: 12396958]
84. Gala Ortiz G, Cuevas Agustín M, Erias Martínez P, de la Hoz Caballer B, Fernández Ordoñez R, Hinojosa Macías M, Boixeda D, Losada Cosmes E. Chronic urticaria and Helicobacter pylori. Ann Allergy Asthma Immunol 2001; 86: 696-698 [PMID: 11428745]
85. Hellmig S, Troch K, Ott SJ, Schwarz T, Fölsch UR. Role of Helicobacter pylori Infection in the treatment and outcome of chronic urticaria. Helicobacter 2008; 13: 341-345 [PMID: 19250508]
86. Hook-Nikanne J, Varjonen E, Harvima RJ, Kosunen TU. Is Helicobacter pylori infection associated with chronic urti-caria? Acta Derm Venereol 2000; 80: 425-426 [PMID: 11243635]
87. Bruscky DM, da Rocha LA, Costa AJ. Recurrence of chronic urticaria caused by reinfection by Helicobacter pylori. Rev Paul Pediatr 2013; 31: 272-275 [PMID: 23828067]
88. Campanati A, Gesuita R, Giannoni M, Piraccini F, Sandroni L, Martina E, Conocchiari L, Bendia E, Di Sario A, Offidani A. Role of small intestinal bacterial overgrowth and Helicobacter pylori infection in chronic spontaneous urticaria: a prospective analysis. Acta Derm Venereol 2013; 93: 161-164 [PMID: 22858910 DOI: 10.2340/00015555-1373]
89. Akashi R, Ishiguro N, Shimizu S, Kawashima M. Clinical study of the relationship between Helicobacter pylori and chronic urticaria and prurigo chronica multiformis: effectiveness of eradication therapy for Helicobacter pylori. J Dermatol 2011; 38: 761-766 [PMID: 21352335 DOI: 10.1111/j.1346-8138.2010.01106.x]
90. Di Campli C, Gasbarrini A, Nucera E, Franceschi F, Ojetti V, Sanz Torre E, Schiavino D, Pola P, Patriarca G, Gasbarrini G. Beneficial effects of Helicobacter pylori eradication on idiopathic chronic urticaria. Dig Dis Sci 1998; 43: 1226-1229 [PMID: 9635612]
91. Daudén E, Jiménez-Alonso I, García-Díez A. Helicobacter pylori and idiopathic chronic urticaria. Int J Dermatol 2000; 39: 446-452 [PMID: 10944090]
92. Chiu YC, Tai WC, Chuah SK, Hsu PI, Wu DC, Wu KL, Huang CC, Ho JC, Ring J, Chen WC. The Clinical Correlations of Helicobacter pylori Virulence Factors and Chronic Spontaneous Urticaria. Gastroenterol Res Pract 2013; 2013: 436727 [PMID: 23956739 DOI: 10.1155/2013/436727]
93. Ersoy O, Ersoy R, Yayar O, Demirci H, Tatlican S. H pylori infection in patients with Behcet's disease. World J Gastroenterol 2007; 13: 2983-2985 [PMID: 17589951]
94. Sentürk O, Ozgür O, Hülagü OS, Cantürk NZ, Celebi A, Karakaya AT. Effect of Helicobacter pylori infection on deep vein thrombosis seen in patients with Behçet's disease. East Afr Med J 2006; 83: 49-51 [PMID: 16642751]
95. Avci O, Ellidokuz E, Simşek I, Büyükgebiz B, Güneş AT. Helicobacter pylori and Behçet's disease. Dermatology 1999; 199: 140-143 [PMID: 10559580]
96. Apan TZ, Gürsel R, Dolgun A. Increased seropositivity of Helicobacter pylori cytotoxin-associated gene-A in Behçet' s disease. Clin Rheumatol 2007; 26: 885-889 [PMID: 17021670 DOI: 10.1007/s10067-006-0416-x]
97. Abdel Hafez HZ, Mahran AM, Hofny EM, Attallah DA, Sayed DS, Rashed H. Alopecia areata is not associated with Helicobacter pylori. Indian J Dermatol 2009; 54: 17-19 [PMID: 20049262 DOI: 10.4103/0019-5154.48979]
98. Abdel-Hafez HZ, Mahran AM, Hofny ER, Attallah DA, Sayed DS, Rashed HA. Is Helicobacter pylori infection associated with alopecia areata? J Cosmet Dermatol 2009; 8: 52-55 [PMID: 19250167]
99. Rigopoulos D, Katsambas A, Karalexis A, Papatheodorou G, Rokkas T. No increased prevalence of Helicobacter pylori in patients with alopecia areata. J Am Acad Dermatol 2002; 46: 141 [PMID: 11756964]
100. Campuzano-Maya G. Cure of alopecia areata after eradication of Helicobacter pylori: a new association? World J Gastroenterol 2011; 17: 3165-3170 [PMID: 21912461 DOI: 10.3748/ wjg.v17.i26.3165]
101. Liebman H. Other immune thrombocytopenias. Semin Hematol 2007; 44: S24-S34 [PMID: 18096469 DOI: 10.1053/j.seminhematol. 2007.11.004]
102. Emilia G, Longo G, Luppi M, Gandini G, Morselli M, Ferrara L, Amarri S, Cagossi K, Torelli G. Helicobacter pylori eradication can induce platelet recovery in idiopathic thrombocytopenic purpura. Blood 2001; 97: 812-814 [PMID: 11157503]
103. Franceschi F, Satta MA, Mentella MC, Penland R, Candelli M, Grillo RL, Leo D, Fini L, Nista EC, Cazzato IA, Lupascu A, Pola P, Pontecorvi A, Gasbarrini G, Genta RM, Gasbarrini A. Helicobacter pylori infection in patients with Hashimoto' s thyroiditis. Helicobacter 2004; 9: 369 [PMID: 15270751 DOI: 10.1111/j.1083-4389.2004.00241.x]
104. Gasbarrini A, Franceschi F, Tartaglione R, Landolfi R, Pola P, Gasbarrini G. Regression of autoimmune thrombocytopenia after eradication of Helicobacter pylori. Lancet 1998; 352: 878 [PMID: 9742983 DOI: 10.1016/S0140-6736(05)60004-9]
105. Stasi R, Rossi Z, Stipa E, Amadori S, Newland AC, Provan D. Helicobacter pylori eradication in the management of patients with idiopathic thrombocytopenic purpura. Am J Med 2005; 118: 414-419 [PMID: 15808140 DOI: 10.1016/j.amjmed.2004.09.014]
106. Suzuki T, Matsushima M, Masui A, Watanabe K, Takagi A, Ogawa Y, Shirai T, Mine T. Effect of Helicobacter pylori eradication in patients with chronic idiopathic thrombocytopenic purpura-a randomized controlled trial. Am J Gastroenterol 2005; 100: 1265-1270 [PMID: 15929755 DOI: 10.1111/ j.1572-0241.2005.41641.x]
107. Gasbarrini A, Franceschi F. Does H. Pylori infection play a role in idiopathic thrombocytopenic purpura and in other autoimmune diseases? Am J Gastroenterol 2005; 100: 1271-1273 [PMID: 15929756 DOI: 10.1111/j.1572-0241.2005.50224.x]
108. Franceschi F, Christodoulides N, Kroll MH, Genta RM. Helicobacter pylori and idiopathic thrombocytopenic purpura. Ann Intern Med 2004; 140: 766-767 [PMID: 15126268]
109. Huber MR, Kumar S, Tefferi A. Treatment advances in adult immune thrombocytopenic purpura. Ann Hematol 2003; 82: 723-737 [PMID: 13680177 DOI: 10.1007/s00277-003-0732-z]
110. Takahashi T, Yujiri T, Shinohara K, Inoue Y, Sato Y, Fujii Y, Okubo M, Zaitsu Y, Ariyoshi K, Nakamura Y, Nawata R, Oka Y, Shirai M, Tanizawa Y. Molecular mimicry by Helicobacter pylori CagA protein may be involved in the pathogenesis of H. pylori-associated chronic idiopathic thrombocytopenic purpura. Br J Haematol 2004; 124: 91-96 [PMID: 14675413]
111. Negrini R, Savio A, Poiesi C, Appelmelk BJ, Buffoli F, Paterlini A, Cesari P, Graffeo M, Vaira D, Franzin G. Antigenic mimicry between Helicobacter pylori and gastric mucosa in the pathogenesis of body atrophic gastritis. Gastroenterology 1996; 111: 655-665 [PMID: 8780570]
112. Conway DS, Lip GY. Helicobacter pylori as the cause of coronary artery restenosis following angioplasty--is the way to a man's heart disease through his stomach? Dig Liver Dis 2001; 33: 214-216 [PMID: 11407664]
113. Stone AF, Mendall MA. Helicobacter pylori is an aetiological factor for ischaemic heart disease: the case in favour. Dig Liver Dis 2000; 32: 62-64 [PMID: 10975757]
114. Papamichael KX, Papaioannou G, Karga H, Roussos A, Mantzaris GJ. Helicobacter pylori infection and endocrine disorders: is there a link? World J Gastroenterol 2009; 15: 2701-2707 [PMID: 19522019]
115. Bassi V, Marino G, Iengo A, Fattoruso O, Santinelli C. Autoimmune thyroid diseases and Helicobacter pylori: the correlation is present only in Graves's disease. World J Gastroenterol 2012; 18: 1093-1097 [PMID: 22416184 DOI: 10.3748/wjg.v18. i10.1093]
116. Bassi V, Santinelli C, Iengo A, Romano C. Identification of a correlation between Helicobacter pylori infection and Graves' disease. Helicobacter 2010; 15: 558-562 [PMID: 21073613 DOI: 10.1111/j.1523-5378.2010.00802.x]
117. Tomasi PA, Dore MP, Fanciulli G, Sanciu F, Realdi G, Delitala G. Is there anything to the reported association between Helicobacter pylori infection and autoimmune thyroiditis? Dig Dis Sci 2005; 50: 385-388 [PMID: 15745105]
118. de Luis DA, Varela C, de La Calle H, Cantón R, de Argila CM, San Roman AL, Boixeda D. Helicobacter pylori infection is markedly increased in patients with autoimmune atrophic thyroiditis. J Clin Gastroenterol 1998; 26: 259-263 [PMID: 9649006]
119. Figura N, Di Cairano G, Lorè F, Guarino E, Gragnoli A, Cataldo D, Giannace R, Vaira D, Bianciardi L, Kristodhullu S, Lenzi C, Torricelli V, Orlandini G, Gennari C. The infection by Helicobacter pylori strains expressing CagA is highly prevalent in women with autoimmune thyroid disorders. J Physiol Pharmacol 1999; 50: 817-826 [PMID: 10695561]
120. Ko GH, Park HB, Shin MK, Park CK, Lee JH, Youn HS, Cho MJ, Lee WK, Rhee KH. Monoclonal antibodies against Helicobacter pylori cross-react with human tissue. Helicobacter 1997; 2: 210-215 [PMID: 9421126]
121. Tomb JF, White O, Kerlavage AR, Clayton RA, Sutton GG, Fleischmann RD, Ketchum KA, Klenk HP, Gill S, Dougherty BA, Nelson K, Quackenbush J, Zhou L, Kirkness EF, Peterson S, Loftus B, Richardson D, Dodson R, Khalak HG, Glodek A, McKenney K, Fitzegerald LM, Lee N, Adams MD, Hickey EK, Berg DE, Gocayne JD, Utterback TR, Peterson JD, Kelley JM, Cotton MD, Weidman JM, Fujii C, Bowman C, Watthey L, Wallin E, Hayes WS, Borodovsky M, Karp PD, Smith HO, Fraser CM, Venter JC. The complete genome sequence of the gastric pathogen Helicobacter pylori. Nature 1997; 388: 539-547 [PMID: 9252185 DOI: 10.1038/41483]
122. Bertalot G, Montresor G, Tampieri M, Spasiano A, Pedroni M, Milanesi B, Favret M, Manca N, Negrini R. Decrease in thyroid autoantibodies after eradication of Helicobacter pylori infection. Clin Endocrinol (Oxf) 2004; 61: 650-652 [PMID: 15521972 DOI: 10.1111/j.1365-2265.2004.02137.x]
123. Larizza D, Calcaterra V, Martinetti M, Negrini R, De Silvestri A, Cisternino M, Iannone AM, Solcia E. Helicobacter pylori infection and autoimmune thyroid disease in young patients: the disadvantage of carrying the human leukocyte antigen-DRB1*0301 allele. J Clin Endocrinol Metab 2006; 91: 176-179 [PMID: 16263823 DOI: 10.1210/jc.2005-1272]
124. Abenavoli L, Arena V, Giancotti F, Vecchio FM, Abenavoli S. Celiac disease, primary biliary cirrhosis and helicobacter pylori infection: one link for three diseases. Int J Immunopathol Pharmacol 2010; 23: 1261-1265 [PMID: 21244776]
125. Muratori L, Bogdanos DP, Muratori P, Lenzi M, Granito A, Ma Y, Mieli-Vergani G, Bianchi FB, Vergani D. Susceptibility to thyroid disorders in hepatitis C. Clin Gastroenterol Hepatol 2005; 3: 595-603 [PMID: 15952102]
126. Vergani D, Bogdanos DP, Baum H. Unusual suspects in primary biliary cirrhosis. Hepatology 2004; 39: 38-41 [PMID: 14752820 DOI: 10.1002/hep.20028]
127. Bogdanos DP, Vergani D. Origin of cross-reactive autoimmunity in primary biliary cirrhosis. Liver Int 2006; 26: 633-635 [PMID: 16842317 DOI: 10.1111/j.1478-3231.2006.01291.x]
128. Bogdanos DP, Lenzi M, Okamoto M, Rigopoulou EI, Muratori P, Ma Y, Muratori L, Tsantoulas D, Mieli-Vergani G, Bianchi FB, Vergani D. Multiple viral/self immunological cross-reactivity in liver kidney microsomal antibody positive hepatitis C virus infected patients is associated with the possession of HLA B51. Int J Immunopathol Pharmacol 2004; 17: 83-92
129. Gregorio GV, Choudhuri K, Ma Y, Pensati P, Iorio R, Grant P, Garson J, Bogdanos DP, Vegnente A, Mieli-Vergani G, Vergani D. Mimicry between the hepatitis C virus polyprotein and antigenic targets of nuclear and smooth muscle antibodies in chronic hepatitis C virus infection. Clin Exp Immunol 2003; 133: 404-413 [PMID: 12930368]
130. Deretzi G, Kountouras J, Polyzos SA, Zavos C, Giartza-Taxidou E, Gavalas E, Tsiptsios I. Gastrointestinal immune system and brain dialogue implicated in neuroinflammatory and neurodegenerative diseases. Curr Mol Med 2011; 11: 696-707 [PMID: 21902649]
131. Long Y, Gao C, Qiu W, Hu X, Shu Y, Peng F, Lu Z. Helicobacter pylori infection in Neuromyelitis Optica and Multiple Sclerosis. Neuroimmunomodulation 2013; 20: 107-112 [PMID: 23295676 DOI: 10.1159/000345838]
132. Yoshimura S, Isobe N, Matsushita T, Yonekawa T, Masaki K, Sato S, Kawano Y, Kira J. Distinct genetic and infectious profiles in Japanese neuromyelitis optica patients according to anti-aquaporin 4 antibody status. J Neurol Neurosurg Psychiatry 2013; 84: 29-34 [PMID: 23038741 DOI: 10.1136/ jnnp-2012-302925]
133. Gavalas E, Kountouras J, Deretzi G, Boziki M, Grigoriadis N, Zavos C, Venizelos I. Helicobacter pylori and multiple sclerosis. J Neuroimmunol 2007; 188: 187-189; author reply 190 [PMID: 17614142 DOI: 10.1016/j.jneuroim.2007.06.007]
134. Kountouras J, Gavalas E, Deretzi G, Boziki M, Zavos C, Chatzopoulos D, Katsinelos P, Giartza-Taxidou E, Grigoriadis N, Venizelos I. Helicobacter pylori with or without its neutrophil-activating protein may be the common denominator associated with multiple sclerosis and neuromyelitis optica. Mult Scler 2010; 16: 376-377; author reply 378-379 [PMID: 20203152 DOI: 10.1177/1352458509360550]
135. Li W, Minohara M, Piao H, Matsushita T, Masaki K, Matsuoka T, Isobe N, Su JJ, Ohyagi Y, Kira J. Association of anti-Helicobacter pylori neutrophil-activating protein antibody response with anti-aquaporin-4 autoimmunity in Japanese patients with multiple sclerosis and neuromyelitis optica. Mult Scler 2009; 15: 1411-1421 [PMID: 19965522 DOI: 10.1177 /1352458509348961]
136. Mohebi N, Mamarabadi M, Moghaddasi M. Relation of helicobacter pylori infection and multiple sclerosis in Iranian patients. Neurol Int 2013; 5: 31-33 [PMID: 23888213 DOI: 10.4081/ ni.2013.e10]
137. Wender M. [Prevalence of Helicobacter pylori infection among patients with multiple sclerosis]. Neurol Neurochir Pol 2003; 37: 45-48 [PMID: 12910828]
138. Li W, Minohara M, Su JJ, Matsuoka T, Osoegawa M, Ishizu T, Kira J. Helicobacter pylori infection is a potential protective factor against conventional multiple sclerosis in the Japanese population. J Neuroimmunol 2007; 184: 227-231 [PMID: 17296235 DOI: 10.1016/j.jneuroim.2006.12.010]
139. Lin TT, Yeh CT, Wu CS, Liaw YF. Detection and partial sequence analysis of Helicobacter pylori DNA in the bile samples. Dig Dis Sci 1995; 40: 2214-2219 [PMID: 7587792]
140. Tanaka A, Prindiville TP, Gish R, Solnick JV, Coppel RL, Keeffe EB, Ansari A, Gershwin ME. Are infectious agents involved in primary biliary cirrhosis? A PCR approach. J Hepatol 1999; 31: 664-671 [PMID: 10551390]
141. Nilsson HO, Taneera J, Castedal M, Glatz E, Olsson R, Wadström T. Identification of Helicobacter pylori and other Helicobacter species by PCR, hybridization, and partial DNA sequencing in human liver samples from patients with primary sclerosing cholangitis or primary biliary cirrhosis. J Clin Microbiol 2000; 38: 1072-1076 [PMID: 10698999]
142. Bogdanos DP, Baum H, Grasso A, Okamoto M, Butler P, Ma Y, Rigopoulou E, Montalto P, Davies ET, Burroughs AK, Vergani D. Microbial mimics are major targets of crossreactivity with human pyruvate dehydrogenase in primary biliary cirrhosis. J Hepatol 2004; 40: 31-39 [PMID: 14672611]
143. Bogdanos DP, Baum H, Gunsar F, Arioli D, Polymeros D, Ma Y, Burroughs AK, Vergani D. Extensive homology between the major immunodominant mitochondrial antigen in primary biliary cirrhosis and Helicobacter pylori does not lead to immunological cross-reactivity. Scand J Gastroenterol 2004; 39: 981-987 [PMID: 15513338]
144. Koutsoumpas A, Mytilinaiou M, Polymeros D, Dalekos GN, Bogdanos DP. Anti-Helicobacter pylori antibody responses specific for VacA do not trigger primary biliary cirrhosisspecific antimitochondrial antibodies. Eur J Gastroenterol Hepatol 2009; 21: 1220 [PMID: 19749508 DOI: 10.1097/ MEG.0b013e32831a4807]
145. Krasinskas AM, Yao Y, Randhawa P, Dore MP, Sepulveda AR. Helicobacter pylori may play a contributory role in the pathogenesis of primary sclerosing cholangitis. Dig Dis Sci 2007; 52: 2265-2270 [PMID: 17393314 DOI: 10.1007/ s10620-007-9803-7]
146. Casswall TH, Németh A, Nilsson I, Wadström T, Nilsson HO. Helicobacter species DNA in liver and gastric tissues in children and adolescents with chronic liver disease. Scand J Gastroenterol 2010; 45: 160-167 [PMID: 20095882 DOI: 10.3109 /00365520903426915]
147. Eksteen B, Grant AJ, Miles A, Curbishley SM, Lalor PF, Hübscher SG, Briskin M, Salmon M, Adams DH. Hepatic endothelial CCL25 mediates the recruitment of CCR9+ guthoming lymphocytes to the liver in primary sclerosing cholangitis. J Exp Med 2004; 200: 1511-1517 [PMID: 15557349]
148. Trivedi PJ, Adams DH. Mucosal immunity in liver autoimmunity: a comprehensive review. J Autoimmun 2013; 46: 97-111 [PMID: 23891169]
149. Nilsson I, Kornilovs'ka I, Lindgren S, Ljungh A, Wadström T. Increased prevalence of seropositivity for non-gastric Helicobacter species in patients with autoimmune liver disease. J Med Microbiol 2003; 52: 949-953 [PMID: 14532338]
150. Dzierzanowska-Fangrat K, Nilsson I, Wozniak M, Jozwiak P, Rozynek E, Woynarowski M, Socha J, Ljungh A, Wadström T. Lack of an association between Helicobacter infection and autoimmune hepatitis in children. Pol J Microbiol 2006; 55: 157-159 [PMID: 17419295]
151. Durazzo M, Pellicano R, Premoli A, Berrutti M, Leone N, Ponzetto A, Rizzetto M. Helicobacter pylori seroprevalence in patients with autoimmune hepatitis. Dig Dis Sci 2002; 47: 380-383 [PMID: 11855554]
152. El-Matary W, Dalzell AM, Ashworth M. Helicobacter pylori and autoimmune hepatitis. Eur J Pediatr 2005; 164: 54-55 [PMID: 15549381 DOI: 10.1007/s00431-004-1555-1]
153. Franceschi F, Brisinda D, Buccelletti F, Ruggieri MP, Gasbarrini A, Sorbo A, Marsiliani D, Venuti A, Fenici P, Gasbarrini G, Silveri NG, Fenici R. Prevalence of virulent Helicobacter pylori strains in patients affected by idiopathic dysrhythmias. Intern Emerg Med 2013; 8: 333-337 [PMID: 21562783 DOI: 10.1007/ s11739-011-0621-8]
154. Fonseca FM, Queiroz DM, Rocha AM, Prata A, Crema E, Rodrigues Junior V, Ramirez LE, Oliveira AG. Seroprevalence of Helicobacter pylori infection in chagasic and nonchagasic patients from the same geographical region of Brazil. Rev Soc Bras Med Trop 2012; 45: 194-198 [PMID: 22534991]
155. Selmi C, Balkwill DL, Invernizzi P, Ansari AA, Coppel RL, Podda M, Leung PS, Kenny TP, Van De Water J, Nantz MH, Kurth MJ, Gershwin ME. Patients with primary biliary cirrhosis react against a ubiquitous xenobiotic-metabolizing bacterium. Hepatology 2003; 38: 1250-1257 [PMID: 14578864 DOI: 10.1053/jhep.2003.50446]
156. Bogdanos DP, Baum H, Okamoto M, Montalto P, Sharma UC, Rigopoulou EI, Vlachogiannakos J, Ma Y, Burroughs AK, Vergani D. Primary biliary cirrhosis is characterized by IgG3 antibodies cross-reactive with the major mitochondrial autoepitope and its Lactobacillus mimic. Hepatology 2005; 42: 458-465 [PMID: 16025495]
157. Bogdanos D, Pusl T, Rust C, Vergani D, Beuers U. Primary biliary cirrhosis following Lactobacillus vaccination for recurrent vaginitis. J Hepatol 2008; 49: 466-473 [PMID: 18644655 DOI: 10.1016/j.jhep.2008.05.022]
158. Smyk DS, Bogdanos DP, Kriese S, Billinis C, Burroughs AK, Rigopoulou EI. Urinary tract infection as a risk factor for autoimmune liver disease: from bench to bedside. Clin Res Hepatol Gastroenterol 2012; 36: 110-121 [PMID: 21907008 DOI: 10.1016/ j.clinre.2011.07.013]
159. Bogdanos DP, Baum H, Vergani D, Burroughs AK. The role of E. coli infection in the pathogenesis of primary biliary cirrhosis. Dis Markers 2010; 29: 301-311 [PMID: 21297249 DOI: 10.3233/DMA-2010-0745]