Infectious serologies and autoantibodies in wegener's granulomatosis and other vasculitides: Novel associations disclosed using the rad BioPlex 2200

Annals of the New York Academy of Sciences

Volumn 1173, Issue , 2009, Pages 649-657

  Lidar, Merav ^a   Lipschitz, Noga ^b   Langevitz, Pnina ^a   Barzilai, Ori ^b   Ram, Maya ^b   Porat Katz, Bat Sheba ^c   Pagnoux, Christian ^d   Guilpain, Philippe ^e   Sinico, Renato Alberto ^f   Radice, Antonella ^f   Bizzaro, Nicola ^g   Damoiseaux, Jan ^h   Tervaert, Jan Willem Cohen ^h   Martin, Javier ⁱ   Guillevin, Loïc ^e   Bombardieri, Stefano ^j   Shoenfeld, Yehuda ^a,b  

^a TEL AVIV UNIVERSITY   (Israel)

^b SHEBA MEDICAL CENTER   (Israel)

^c KAPLAN MEDICAL CENTER   (Israel)

^d Cochin Hospital ^*  (France)

^e UNIVERSITÉ PARIS DESCARTES   (France)

^f SAN CARLO BORROMEO HOSPITAL   (Italy)

^g Civil Hospital   (Italy)

^h MAASTRICHT UNIVERSITY MEDICAL CENTER   (Netherlands)

ⁱ INSTITUTO DE PARASITOLOGÍA Y BIOMEDICINA LÓPEZ NEYRA   (Spain)

^j UNIVERSITY OF PISA   (Italy)

more..

Author keywords

Infection; Pathogenesis; Vasculitis

Indexed keywords

AUTOANTIBODY; BACTERIUM ANTIBODY; EARLY ANTIGEN; HELICOBACTER PYLORI ANTIBODY; HEPATITIS C ANTIBODY; IMMUNOGLOBULIN G ANTIBODY; IMMUNOGLOBULIN M ANTIBODY; UNCLASSIFIED DRUG; VIRUS CAPSID ANTIGEN;

ANALYZER; BLOOD SAMPLING; CHURG STRAUSS SYNDROME; CONFERENCE PAPER; CONTROLLED STUDY; CYTOMEGALOVIRUS; ENZYME LINKED IMMUNOSORBENT ASSAY; EPSTEIN BARR VIRUS; GASTROINTESTINAL DISEASE; GIANT CELL ARTERITIS; HELICOBACTER PYLORI; HEPATITIS B VIRUS; HEPATITIS C VIRUS; HUMAN; KIDNEY DISEASE; MAJOR CLINICAL STUDY; MICROSCOPIC POLYANGIITIS; PHENOTYPE; POLYARTERITIS NODOSA; PREVALENCE; SACCHAROMYCES CEREVISIAE; SEROLOGY; THROMBOPHILIA; TOXOPLASMA GONDII; TREPONEMA PALLIDUM; VASCULITIS; VIRUS TITRATION; WEGENER GRANULOMATOSIS;

CYTOMEGALOVIRUS; HELICOBACTER PYLORI; HEPATITIS B VIRUS; HEPATITIS C VIRUS; HUMAN HERPESVIRUS 4; MIRIDAE; SACCHAROMYCES CEREVISIAE; TOXOPLASMA GONDII; TREPONEMA PALLIDUM;

EID: 67349123984     PISSN: 00778923     EISSN: 17496632     Source Type: Book Series    
DOI: 10.1111/j.1749-6632.2009.04641.x     Document Type: Conference Paper

References (72)

1. Shoenfeld, Y., B. Gilburd, M. Abu-Shakra, et al. 2008. The mosaic of autoimmunity: genetic factors involved in autoimmune diseases-2008. Isr. Med. As-soc. J. 10: 3-7.
2. Shoenfeld, Y., G. Zandman-Goddard, L. Stojanovich, et al. 2008. The mosaic of au-toimmunity: hormonal and environmental factors involved in autoimmune diseases-2008. Isr. Med. Assoc. J. 10: 8-12. (Pubitemid 351649455)
3. Shoenfeld, Y., M. Blank, M. Abu-Shakra, et al. 2008. The mosaic of autoimmunity: prediction, autoanti-bodies, and therapy in autoimmune diseases-2008. Isr. Med. Assoc. J. 10: 13-19.
4. Rodriguez-Pla, A. & J.H. Stone. 2006. Vasculitis and systemic infections. Curr. Opin. Rheumatol. 18: 39-47.
5. Cohen-Teravet, J.W. & C.A. Stegeman. 2004. Infections and vaculitis. In Infections and Autoimmunity. Y. Shoenfeld & N.R. Rose, Eds.: 549-57. Elsevier. Amsterdam, San Diego, UK.
6. Shoenfeld, Y. 1996. Common infections, idiotypic dysregulation, autoantibody spread and induction of autoimmune diseases. J. Autoimmun. 9: 235-239.
7. Stegeman, C.A., J.W. Tervaert, P.E. de Jong & C.G. Kallenberg. 1996. Trimethoprim-sulfamethoxazole (co-trimoxazole) for the prevention of relapses of We-gener's granulomatosis. Dutch Co-Trimoxazole We-gener Study Group. N. Engl. J. Med. 335: 16-20.
8. Popa, E.R. & J.W. Tervaert. 2003. The relation between Staphylococcus aureus and Wegener's granu-lomatosis: current knowledge and future directions. Intern. Med. 42: 771-780.
9. George, J., Y. Levy, C.G. Kallenberg & Y. Shoen-feld. 1997. Infections and Wegener's granulomatosis-a cause and effect relationship? QJM 90: 367-373.
10. Stegeman, C.A., J.W. Tervaert, W.J. Sluiter, et al. 1994. Association of chronic nasal carriage of Staphy-lococcus aureus and higher relapse rates in Wegener granulomatosis. Ann. Intern. Med. 120: 12-17.
11. Kallenberg, C.G. 2004. The role of bacterial infections for the initiation and exacerbation of systemic vasculitis. Autoimmun. Rev. 3(Suppl 1): S45-47.
12. Voswinkel, J., A. Mueller, J.A. Kraemer, et al. 2006. B lymphocyte maturation in Wegener's granulomato-sis: a comparative analysis of VH genes from en-donasal lesions. Ann. Rheum. Dis. 65: 859-864.
13. Schultz, H. 2007. From infection to autoimmunity: A new model for induction of ANCA against the bactericidal/permeability increasing protein (BPI). Au-toimmun. Rev. 6: 223-227.
14. Kallenberg, C.G., A. Rarok, C.A. Stegeman & P.C. Limburg. 2002. New insights into the pathogenesis of antineutrophil cytoplasmic autoantibody-associated vasculitis. Autoimmun. Rev. 1: 61-66.
15. Wiik, A. 2004. Systemic small vessel vasculitis: patho-physiological aspects of antineutrophil cytoplasm antibodies (ANCA). A review on recent findings. Au-toimmun. Rev. 3: S51-53.
16. Gower, R.G., W.F. Sausker, P.F. Kohler, et al. 1978. Small vessel vasculitis caused by hepatitis B virus immune complexes. Small vessel vasculitis and HBsAG. J. Allergy Clin. Immunol. 62: 222-228.
17. Ferri, C. & S. Bombardieri. 2004. HCV and Cryoglobulinemia. In Infection and Autoimmunity. Y. Shoenfeld & N.R. Rose, Eds.: 201-212. Elsevier. Amsterdam, San Diego, UK.
18. Agnello, V. 1997. The etiology and pathophysiology of mixed cryoglobulinemia secondary to hepatitis C virus infection. Springer Semin. Immunopathol. 19: 111-129. (Pubitemid 27417532)
19. Guillevin, L., F. Lhote, P. Cohen, et al. 1995. Pol-yarteritis nodosa related to hepatitis B virus. A prospective study with long-term observation of 41 patients. Medicine (Baltimore) 74: 238-253.
20. Guillevin, L., A. Mahr, P. Callard, et al. 2005. Hepatitis B virus-associated polyarteritis nodosa: clinical characteristics, outcome, and impact of treatment in 115 patients. Medicine (Baltimore) 84: 313-322.
21. Naides, S.J. 2002. Known causes of vasculitis in man. Cleve. Clin. J. Med. 69(Suppl 2): SII15-19.
22. Guillevin, L., F. Lhote, B. Jarrousse, et al. 1992. Pol-yarteritis nodosa related to hepatitis B virus. A retrospective study of 66 patients. Ann. Med. Interne. (Paris) 143(Suppl 1): 63-74.
23. Guillevin, L., F. Lhote & R. Gherardi. 1997. The spectrum and treatment of virus-associated vasculi-tides. Curr. Opin. Rheumatol. 9: 31-36.
24. Pugliese, A., T. Beltramo, D. Torre & D. Roccatello. 2007. Parvovirus B19 and immune disorders. Cell Biochem. Funct. 25: 639-641.
25. Guillevin, L. 2008. Vasculitides in the context of HIV infection. AIDS 22(Suppl 3): S27-33.
26. Mandell, B.F. & L.H. Calabrese. 1998. Infections and systemic vasculitis. Curr. Opin. Rheumatol. 10: 51.
27. Pagnoux, C., P. Cohen & L. Guillevin. 2006. Vas-culitides secondary to infections. Clin. Exp. Rheumatol. 24(2 Suppl 41): S71-81.
28. Pordeus, V., M. Szyper-Kravitz, R.A. Levy, et al. 2008. Infections and Autoimmunity: A Panorama. Clin. Rev. Allergy Immunol. 34: 283-299.
29. Somer, T. & S.M. Finegold. 1995. Vasculitides associated with infections, immunization, and antimicrobial drugs. Clin. Infect. Dis. 20: 1010-1036.
30. Meyer, M.F., B. Hellmich, S. Kotterba & H. Schatz. 2000. Cytomegalovirus infection in systemic necro-tizing vasculitis: causative agent or opportunistic infection? Rheumatol. Int. 20: 35-38.
31. Gilden, D.H., R. Mahalingam, R.J. Cohrs, et al. 2002. The protean manifestations of varicella-zoster virus vasculopathy. J. Neurovirol. 8(Suppl 2): 75-79. (Pubitemid 36097780)
32. Parola, P., C.D. Paddock & D. Raoult. 2005. Tick-borne rickettsioses around the world: emerging diseases challenging old concepts. Clin. Microbiol. Rev. 18: 719-756.
33. Kennedy, J.L., J.J. Barnard & J.A. Prahlow. 2006. Syphilitic coronary artery ostial stenosis resulting in acute myocardial infarction and death. Cardiology 105: 25-29.
34. Nadelman, R.B. & G.P. Wormser. 1998. Lyme bor-reliosis. Lancet 352: 557-565.
35. Avcin, T., M. Canova, P. Guilpain, et al. 2008. Infections, connective tissue diseases and vasculitis. Clin. Exp. Rheumatol. 26(1 Suppl 48): S18-26.
36. Doria, A., S. Zampieri & P. Sarzi-Puttini. 2008. Exploring the complex relationships between infections and autoimmunity. Autoimmun. Rev. 8: 89-91.
37. Bach, J.F. 2005. Infections and autoimmune diseases. J. Autoimmun. 25(Suppl): 74-80.
38. Ram, M., J.M. Anaya, O. Barzilai, et al. 2008. The putative protective role of hepatitis B virus (HBV) infection against autoimmune disorders. Autoimmun. Rev. 7: 621-625.
39. Barzilai, O., Y. Sherer, M. Ram, et al. 2007. Epstein-Barr virus and cytomegalovirus in autoimmune diseases: are they truly notorious? A preliminary report. Ann. N. Y. Acad. Sci. 1108: 567-577.
40. Zandman-Goddard, G., Y. Berkun, O. Barzilai, et al. 2008. Neuropsychiatric lupus and infectious triggers. Lupus 17: 380-384.
41. Ferri, C. & M.T. Mascia. 2006. Cryoglobulinemic vasculitis. Curr. Opin. Rheumatol. 18: 54-63.
42. Vassilopoulos, D. 2004. Hepatitis C Infection and Vasculitis. In Infection and Autoimmunity. Y. Shoenfeld & N.R. Rose, Eds.: 189-200. Elsevier. Amsterdam, San Diego, UK.
43. Genereau, T., A. Martin, O. Lortholary, et al. 1998. Temporal arteritis symptoms in a patient with hepatitis C virus associated type II cryoglobulinemia and small vessel vasculitis. J. Rheumatol. 25: 183-185.
44. Cojocaru, M., I.M. Cojocaru & S.A. Iacob. 2006. Prevalence of anti-neutrophil cytoplasmic antibodies in patients with chronic hepatitis C infection associated mixed cryoglobulinemia. Rom. J. Intern. Med. 44: 427.
45. Wilson, L.E., D. Widman, S.H. Dikman & P.D. Gorevic. 2002. Autoimmune disease complicating antiviral therapy for hepatitis C virus infection. Semin. Arthritis Rheum. 32: 163-173.
46. Dumoulin, FL.LL, T. Sauerbruch & U. Spengler. 1999. Autoimmunity induced by interferon-alpha therapy for chronic viral hepatitis. Biomed. Pharma-cother. 53: 242-254.
47. Nerheim, P.L., J.L. Meier, M.A. Vasef, et al. 2004. Enhanced cytomegalovirus infection in atherosclerotic human blood vessels. ASIP 164: 589-600.
48. Lamprecht, P.V.C.A., A. Muller, E. Csernok, et al. 2003. Alterations in the phenotype of CMV-specific and total CD8 +T-cell populations in Wegener's granulomatosis. Cell Immunol. 224: 1-7.
49. Gandhi, M.K. & R. Khanna. 2004. Human cy-tomegalovirus: clinical aspects, immune regulation, and emerging treatments. Lancet Infect. Dis. 4: 725-738.
50. Charlier, C., C. Henegar, O. Launay, et al. 2008. Risk factors for major infections in Wegener's gran-ulomatosis: analysis of 113 patients. Ann. Rheum. Dis.
51. Taniwaki, S., M. Kataoka, H. Tanaka, et al. 1997. Multiple ulcers of the ileum due to Cytomegalovirus infection in a patient who showed no evidence of an immunocompromised state. J. Gastroenterol. 32: 548-552.
52. Orloff, J.J., R. Saito, S. Lasky & H. Dave. 1989. Toxic megacolon in cytomegalovirus colitis. Am. J. Gastroen-terol. 84: 794-797.
53. Lee, S., K. Lee, J. Han, et al. 2006. Epstein-Barr virus antibodies in Kawasaki disease. Yonsei Med. J. 47: 475.
54. Caldeira, T., C. Meireles, F. Cunha, et al. 2007. Systemic polyarteritis nodosa associated with acute Epstein-Barr virus infection. Clin. Rheumatol. 26: 1733-1735.
55. Murakami, K.O.M., S.X. Hu, H. Kanno, et al. 1998. Large-vessel arteritis associated with chronic active Epstein-Barr virus infection. Arthritis Rheum. 41: 369-373.
56. Sun, A.C.J., C.T. Chu, B.Y. Liu, et al. 1998. Preliminary evidence for an association of Epstein-Barr virus with pre-ulcerative oral lesions in patients with recurrent aphthous ulcers or Behçet's disease. J. O r a l . Pathol. Med. 27: 168-175.
57. Berggren, M.A., L. Heinlen, A. Isaksson, et al. 2007. EBNA1 expression in a lung transplant recipient with hypocomplementemic urticarial vasculitis syndrome. J. M e d . V i r o l . 79: 963-969.
58. Kim, C., Y. Woo, H. Kook, et al. 2004. Henoch-Schonlein purpura nephritis associated with Epstein-Barr virus infection in twins. Pediatr. Nephrol. 19: 247-248.
59. Rasmussen, N., J. Petersen, E. Ralfkiaer, et al. 1988. Spontaneous and induced immunoglobulin synthesis and anti-neutrophil cytoplasm antibodies in Wegener's granulomatosis: relation to leukocyte sub-populations in blood and active lesions. Rheumatol. Int. 8: 153-158.
60. Mayet, W.J., E. Hermann, B. Kiefer, et al. 1991. In vitro production of anti-neutrophilocyte-cytoplasm-antibodies (Anca) by Epstein-Barr virus-transformed B-cell lines in Wegener's granulomatosis. Autoimmunity 11: 13-19.
61. Cohen, J.I. 2000. Epstein-Barr virus infection. N. Engl. J. Med. 343: 481-492.
62. Oshima, T., R. Ozono, Y. Yano, et al. 2005. Association of Helicobacter pylori infection with systemic inflammation and endothelial dysfunction in healthy male subjects. J. Am. Coll. Cardiol. 45: 1219-1222.
63. Khairy, P., S. Rinfret, J.C. Tardif, et al. 2003. Absence of association between infectious agents and endothe-lial function in healthy young men. Circulation 107: 1966.
64. Ersoy, O., R. Ersoy, O. Yayar, et al. 2007. H pylori infection in patients with Behcet's disease. Wo r l d J. Gastroenterol. 13: 2983.
65. Avci, O., E. Ellidokuz, I. Simsek, et al. 1999. He-licobacter pylori and Behcet's Disease. Dermatology 199: 140-143.
66. Novak, J., Z. Szekanecz, J. Sebesi, et al. 2003. Elevated levels of anti-Helicobacter pylori antibodies in Henoch-Schonlein Purpura. Autoimmunity 36: 307-311.
67. Cecchi, R. & E. Torelli. 1998. Schönlein-Henoch purpura in association with duodenal ulcer and gastric Helicobacter pylori infection. J. Dermatol. 25: 482-484.
68. Suerbaum, S. & P. Michetti. 2002. Helicobacter pylori Infection. N. Engl. J. Med. 347: 1175-1186.
69. Raus, P., P. Stalmans, E. Demeuter, et al. 2001. Unusual retinal vasculitis in a patient with protein S deficiency and systemic toxoplasmosis: a case report. Bull. Soc. Belge Opthalmol. 279: 7-12.
70. Ellis, M.E., A.K. Webb & E.M. Dunbar. 1984. Toxoplasmosis associated with digital vasculitis and immunodeficiency-a dilemma in diagnosis. Postgrad. Med. J. 60: 616-617.
71. Nakamura, M., M. Nagai, Y. Shiga, et al. 2005. Toxoplasma encephalitis in a patient receiving cy-closporine monotherapy for Behcet disease. Rinsho Shinkeigaku 45: 105-110.
72. Birgisdottir, A., H. Asbjornsdottir, E. Cook, et al. 2006. Seroprevalence of Toxoplasma gondii in Sweden, Estonia and Iceland. Scand. J. Infect. Dis. 38: 625-631.