Protective effect of dry olive leaf extract in adrenaline induced DNA damage evaluated using in vitro comet assay with human peripheral leukocytes

Toxicology in Vitro

Volumn 28, Issue 3, 2014, Pages 451-456

  Čabarkapa, Andrea ^a   Živković, Lada ^a   Žukovec, Dijana ^a   Djelić, Ninoslav ^b   Bajić, Vladan ^c   Dekanski, Dragana ^c   Spremo Potparević, Biljana ^a  

^a UNIVERSITY OF BELGRADE   (Serbia)

^b UNIVERSITY OF BELGRADE   (Serbia)

^c Research and Development   (Serbia)

Author keywords

(CAS 329 63 5); Adrenaline; Comet assay; Dry olive leaf extract (DOLE); Oxidative stress

Indexed keywords

ADRENALIN; ANTIOXIDANT; DRY OLIVE LEAF EXTRACT; PLANT EXTRACT; UNCLASSIFIED DRUG;

ADULT; ANTIOXIDANT ACTIVITY; ARTICLE; COMET ASSAY; CONCENTRATION RESPONSE; CONTROLLED STUDY; DNA DAMAGE; FEMALE; GENOTOXICITY; HUMAN; HUMAN CELL; IN VITRO STUDY; LEUKOCYTE; MALE; OLIVE; OXIDATIVE STRESS;

ADRENALINE (CAS 329-63-5); COMET ASSAY; DRY OLIVE LEAF EXTRACT (DOLE); OXIDATIVE STRESS;

ADULT; ANTIOXIDANTS; COMET ASSAY; DNA DAMAGE; DOSE-RESPONSE RELATIONSHIP, DRUG; EPINEPHRINE; FEMALE; HUMANS; LEUKOCYTES; MALE; OLEA; OXIDATIVE STRESS; PHENOLS; PLANT EXTRACTS; PLANT LEAVES; REACTIVE OXYGEN SPECIES; YOUNG ADULT;

EID: 84892897826     PISSN: 08872333     EISSN: 18793177     Source Type: Journal    
DOI: 10.1016/j.tiv.2013.12.014     Document Type: Article

References (38)

1. Abo Ghanema I.I., Sadek K.M. Olive leaves extract restored the antioxidant perturbations in red blood cells hemolysate in streptozotocin induced diabetic rats. WASET 2012, 64:159-165.
2. Anderson D., Yu T.W., Phillips B.J., Schmezer P. The effect of various antioxidants and other modifying agents on oxygen-radical-generated DNA damage in human lymphocytes in the comet assay. Mutat. Res. 1994, 307:261-271.
3. Anter J., Fernandez-Bedmar Z., Villatoro-Pulido M., Demyda-Peyras S., Moreno-Millan M., Alonso-Moraga A., et al. A pilot study on the DNA-protective, cytotoxic, and apoptosis-inducing properties of olive-leaf extracts. Mutat. Res. 2011, 723(2):165-170.
4. Arantes-Rodrigues R., Henriques A., Pires M.J., Colaço B., Calado A.M., Rema P., et al. High doses of olive leaf extract induce liver changes in mice. Food Chem. Toxicol. 2011, 49(9):1989-1997.
5. Arts I.C.W., Hollman P.C.H. Polyphenols and disease risk in epidemiologic studies. Am. J. Clin. Nutr. 2005, 81(1):317-325.
6. Behonick G.S., Novak M.J., Nealley E.W., Baskin S.I. Toxicology update: the cardiotoxicity of the oxidative stress metabolites of catecholamines (Aminochromes). J. Appl. Toxicol. 2001, 21(1):15-22.
7. Benavente-Garcia O., Castillo J., Lorente J., Ortuno A., Del Rio J.A. Antioxidant activity of phenolics extracted from Olea europaea L. leaves. Food Chem. 2000, 68(4):457-462.
8. Bindoli A., Deeble D.J., Rigobello M.P., Galzigna L. Direct and respiratory chain-mediated redox cycling of adrenochrome. Biochim. Biophys. Acta 1990, 26:349-356.
9. Cavalieri E.L., Rogan E.G. A unifying mechanism in the initiation of cancer and other diseases by catechol quinones. Ann. N. Y. Acad. Sci. 2004, 1028:247-257.
10. Chiaramonte R., Bartolini E., Riso P., Calzavara E., Erba D., Testolin G., et al. Oxidative stress signalling in the apoptosis of Jurkat T-lymphocytes. J. Cell Biochem. 2001, 82:437-444.
11. 2 toxicity in insulin secreting β-cells. Acta Biochim. Pol. 2011, 58(1):45-50.
12. Dekanski D., Janićijević-Hudomal S., Tadić V., Marković G., Arsić I., Mitrović D. Phytochemical analysis and gastroprotective activity of an olive leaf extract. J. Serb. Chem. Soc. 2009, 74(4):367-377.
13. Dekanski D., Janićijević-Hudomal S., Ristić S., Radonjić N.V., Petronijević N.D., Piperski V., et al. Attenuation of cold restraint stress-induced gastric lesions by an olive leaf extract. Gen. Physiol. Biophys 2009, 28:135-142. Special Issue.
14. Djelić N., Anderson D. The effect of the antioxidant catalase on oestrogens, triiodothyronine, and noradrenaline in the comet assay. Teratog. Carcinog. Mutagen. Suppl. 2003, 2:69-81.
15. Djelić N., Djelić D., Spremo-Potparević B., Marković B., Živković L. Cytogenetic analysis of the effects of epinephrine on cultured human lymphocytes. Acta Vet-Beograd 2003, 53:113-120.
16. Dobrzynska M.M., Baumgartner A., Anderson D. Antioxidants modulate thyroid hormone and noradrenaline-induced DNA damage in human sperm. Mutagenesis 2004, 19:325-330.
17. El-Damrawy S.Z. Alleviate the oxidative stress in aged rabbit bucks by using olive leave extract. Egypt. Poult. Sci. 2011, 31:737-744.
18. Fares R., Bazzi S., Baydoun S.E., Abdel-Massih R.M. The antioxidant and anti-proliferative activity of the lebanese Olea europaea extract. Plant Foods Hum. Nutr. 2011, 66(1):58-63.
19. Flint M.S., Baum A., Chambers W.H., Jenkins F.J. Induction of DNA damage, alteration of DNA repair and transcriptional activation by stress hormones. Psychoneuroendocrinology 2007, 32(5):470-479.
20. Franke S.I.R., Pra D., Erdtmann B., Henriques J.A.P., Da Silva J. Influence of orange juice over the genotoxicity induced by alkylating agents: an in vivo analysis. Mutagenesis 2005, 20(4):279-283.
21. Genova M.L., Abd-Elsalam N.M., Mahdy E.S.M.E., Bernacchia A., Lucarini M., Pedulli G.F., et al. Redox cycling of adrenaline and adrenochrome catalysed by mitochondrial Complex I. Arch. Biochem. Biophys. 2006, 447:167-173.
22. Halliwell B., Gutteridge J.M.C. Oxygen toxicity, oxygen radicals, transition metals and disease. Biochem. J. 1984, 219:1-14.
23. Khansari N., Shakiba Y., Mahmoudi M. Chronic inflammation and oxidative stress as a major cause of age-related diseases and cancer. Recent. Pat. Inflamm. Allergy. Drug Discov. 2009, 3:73-80.
24. Le Tutour B., Guedon D. Antioxidative activities of Olea europea L. leaves and related phenolic compounds. Phytochemistry 1992, 31(4):1173-1178.
25. Lee O.H., Lee B.Y. Antioxidant and antimicrobial activities of individual and combined phenolics in Olea europaea leaf extract. Bioresour. Technol. 2010, 101(10):3751-3754.
26. Lee-Huang S., Zhang L., Lin Huang P., Chang Y.-T., Huang P.L. Anti-HIV activity of olive leaf extract (OLE) and modulation of host cell gene expression by HIV-1 infection and OLE treatment. Biochem. Biophys. Res. Commun. 2003, 307(4):1029-1037.
27. Liehr J.G. Genotoxicity of the steroidal oestrogens oestrone and oestradiol: possible mechanism of uterine and mammary cancer development. Hum. Reprod. Update 2001, 7:273-281.
28. Masella R., Vari R., D'Archivio M., Di Benedetto R., Matarrese P., Malorni W., et al. Extra virgin olive oil biophenols inhibit cell-mediated oxidation of LDL by increasing the mRNA transcription of glutathione-related enzymes. J. Nutr. 2004, 134:785-791.
29. Mijatović S., Timotijević G., Miljković Dj., Radović J., Maksimović-Ivanić D., Dekanski D., et al. Multiple antimelanoma potential of dry olive leaf extract. Int. J. Cancer 2011, 128:1955-1965.
30. Miljković D., Dekanski D., Miljković Z., Momčilović M. Dry olive leaf extract ameliorates experimental autoimmune encephalomyelitis. Clin. Nutr. 2009, 28:346-350.
31. Miura T., Muraoka S., Fujimoto Y., Zhao K. DNA damage induced by catechol derivatives. Chem. Biol. Interact. 2000, 126. 125-13.
32. Moldeus P., Nordenskjold M., Bolcsfoldi G., Eiche A., Haglund U., Lambert B. Genetic toxicity of dopamine. Mutat. Res. 1983, 124:9-24.
33. Nousis L., Doulias P.T., Aligiannis N., Bazios D., Agalias A., Galaris D., et al. DNA protecting and genotoxic effects of olive oil related components in cells exposed to hydrogen peroxide. Free Radic. Res. 2005, 39(7):787-795.
34. Okamoto T., Adachi K., Muraishi A., Seki Y., Hidaka T., Toshima H. Induction of DNA breaks in cardiac myoblast cells by norepinephrine. Biochem. Mol. Biol. Int. 1996, 38(4):821-827.
35. Prochazkova D., Bousova I., Wilhelmova N. Antioxidant and prooxidant properties of flavonoids. Fitoterapia 2011, 82:513-523.
36. Singh N.P. Apoptosis by DNA diffusion assay. Methods Mol. Med. 2005, 111:55-67.
37. Singh N.P., McCoy M.T., Tice R.R., Schneider E.L. A simple technique for quantitation of low levels of DNA damage in individual cells. Exp. Cell Res. 1988, 175:184-191.
38. Turkez H., Togar B. Olive (Olea europaea L.) leaf extract counteracts genotoxicity and oxidative stress of permethrin in human lymphocytes. J. Toxicol. Sci. 2011, 36(5):531-537.