Cyclic adenosine 3'-5'-monophosphate (cAMP) exerts proliferative and anti-proliferative effects in pituitary cells of different types by activating both cAMP-dependent protein kinase A (PKA) and exchange proteins directly activated by cAMP (Epac)

Molecular and Cellular Endocrinology

Volumn 383, Issue 1-2, 2014, Pages 193-202

  Vitali, E ^a   Peverelli, E ^a   Giardino, E ^a   Locatelli, M ^a   Lasio, G B ^b   Beck Peccoz, P ^a   Spada, A ^a   Lania, A G ^c   Mantovani, G ^a  

^a FONDAZIONE IRCCS CA GRANDA OSPEDALE MAGGIORE POLICLINICO   (Italy)

^b HUMANITAS CLINICAL AND RESEARCH CENTER   (Italy)

^c UNIVERSITY OF MILAN   (Italy)

Author keywords

CAMP; CAMP dependent protein kinase A (PKA); Exchange proteins directly activated by cAMP (Epac)

Indexed keywords

ANTIPORTER; CYCLIC AMP; CYCLIC AMP DEPENDENT PROTEIN KINASE; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; CYCLIN D1; DNA; PROTEIN EPAC; RAP1 PROTEIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTIPROLIFERATIVE ACTIVITY; ARTICLE; CANCER CELL CULTURE; CELL DIFFERENTIATION; CELL PROLIFERATION; CELL TYPE; DNA SYNTHESIS; ENZYME ACTIVATION; GROWTH HORMONE SECRETING ADENOMA; HUMAN; HUMAN CELL; HUMAN TISSUE; HYPOPHYSIS ADENOMA; HYPOPHYSIS CELL; NONHUMAN; PRIORITY JOURNAL; PROLACTINOMA; PROTEIN EXPRESSION; RAT;

CAMP; CAMP-DEPENDENT PROTEIN KINASE A (PKA); EXCHANGE PROTEINS DIRECTLY ACTIVATED BY CAMP (EPAC);

ADENOMA; ANIMALS; CELL PROLIFERATION; CYCLIC AMP; CYCLIC AMP RESPONSE ELEMENT-BINDING PROTEIN; CYCLIC AMP-DEPENDENT PROTEIN KINASES; CYCLIN D1; GENE EXPRESSION REGULATION, NEOPLASTIC; GONADOTROPHS; GUANINE NUCLEOTIDE EXCHANGE FACTORS; HUMANS; LACTOTROPHS; PITUITARY GLAND; PITUITARY NEOPLASMS; PROLACTINOMA; PROTEIN SUBUNITS; RAP1 GTP-BINDING PROTEINS; RATS; SIGNAL TRANSDUCTION; SOMATOTROPHS;

EID: 84892885817     PISSN: 03037207     EISSN: 18728057     Source Type: Journal    
DOI: 10.1016/j.mce.2013.12.006     Document Type: Article

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