Multicolor lineage tracing methods and intestinal tumors

Journal of Gastroenterology

Volumn 48, Issue 4, 2013, Pages 422-433

  Yanai, Hirotsugu ^a   Tanaka, Toshihiro ^a   Ueno, Hiroo ^a  

^a KANSAI MEDICAL UNIVERSITY   (Japan)

Author keywords

Chimeras; Intestinal stem cells; Intestinal tumors; Lineage tracing; Mosaic

Indexed keywords

WNT PROTEIN; FLUORESCENT DYE; PHOTOPROTEIN;

BENIGN TUMOR; CANCER GROWTH; CHIMERA; CLONE; COLON TUMOR; DEVELOPMENTAL BIOLOGY; FLUORESCENCE; GENE MUTATION; GENETIC LINKAGE; HUMAN; IN VITRO STUDY; INTESTINE EPITHELIUM CELL; INTESTINE TUMOR; MALIGNANT NEOPLASTIC DISEASE; NONHUMAN; PRIORITY JOURNAL; REVIEW; SMALL INTESTINE TUMOR; STEM CELL; WNT SIGNALING PATHWAY; ANIMAL; CELL LINEAGE; INTESTINE MUCOSA; METABOLISM; MOUSE; PATHOLOGY; PHYSIOLOGY;

ANIMALS; CELL LINEAGE; CHIMERA; FLUORESCENT DYES; INTESTINAL MUCOSA; INTESTINAL NEOPLASMS; LUMINESCENT PROTEINS; MICE; STEM CELLS; WNT SIGNALING PATHWAY;

EID: 84892876801     PISSN: 09441174     EISSN: 14355922     Source Type: Journal    
DOI: 10.1007/s00535-012-0736-3     Document Type: Review

References (77)

1. Zuelzer WW, Beattie KM, Reisman LE. Generalized unbalanced mosaicism attributable to dispermy and probable fertilization of a polar body. Am J Hum Genet. 1964;16: 38-51.
2. Tarkowski AK. Experiments on the development of isolated blastomers of mouse eggs. Nature. 1959;184: 1286-7.
3. Tarkowski AK. Experimental studies on regulation in the development of isolated blastomeres of mouse eggs. Acta Theriologica. 1959; 3: 191-267.
4. Tarkowski AK. Mouse chimaeras developed from fused eggs. Nature. 1961;190: 857-60.
5. Gardner RL. Mouse chimeras obtained by the injection of cells into the blastocyst. Nature. 1968;220(5167): 596-7.
6. Gardner RL, Rossant J. Investigation of the fate of 4-5 day postcoitum mouse inner cell mass cells by blastocyst injection. J Embryol Exp Morphol. 1979;52: 141-52.
7. Evans MJ, Kaufman MH. Establishment in culture of pluripotential cells from mouse embryos. Nature. 1981;292(5819): 154-6.
8. Martin GR. Isolation of a pluripotent cell line from early mouse embryos cultured in medium conditioned by teratocarcinoma stem cells. Proc Natl Acad Sci USA. 1981;78(12): 7634-8.
9. Tam PP, Tan SS. The somitogenetic potential of cells in the primitive streak and the tail bud of the organogenesis-stage mouse embryo. Development. 1992;115(3): 703-15.
10. Tan SS, Williams EA, Tam PPL. X-chromosome inactivation occurs at different times in different tissues of the post-implantation mouse embryo. Nat Genet. 1993;3(2): 170-4.
11. Tan SS, Breen S. Radial mosaicism and tangential cell dispersion both contribute to mouse neocortical development. Nature. 1993;362(6421): 638-40.
12. McLaren A. Mammalian chimeras. Cambridge University Press, Cambridge; 1976.
13. Ueno H, Weissman IL. The origin and fate of yolk sac hematopoiesis: application of chimera analyses to developmental studies. Int J Dev Biol. 2010;54(6-7): 1019-31.
14. Ponder BA, et al. Derivation of mouse intestinal crypts from single progenitor cells. Nature. 1985;313(6004): 689-91.
15. Griffiths DF, et al. Demonstration of somatic mutation and colonic crypt clonality by X-linked enzyme histochemistry. Nature. 1988;333(6172): 461-3.
16. McLaren A. Numerology of development. Nature. 1972;239 (5370): 274-6.
17. Nagy A, Gertsenstein M, Vintersten K, Behringer R. Manipulating the mouse embryo: a laboratory manual. 3rd ed. New York: Cold Spring Harbor Laboratory Press; 2003.
18. Shaner NC, et al. Improved monomeric red, orange and yellow fluorescent proteins derived from Discosoma sp. red fluorescent protein. Nat Biotechnol. 2004;22(12): 1567-72.
19. Shaner NC, Steinbach PA, Tsien RY. A guide to choosing fluorescent proteins. Nat Methods. 2005;2(12): 905-9.
20. Ueno H, Weissman IL. Clonal analysis of mouse development reveals a polyclonal origin for yolk sac blood islands. Dev Cell. 2006;11(4): 519-33.
21. Miyazaki J, et al. Expression vector system based on the chicken beta-actin promoter directs efficient production of interleukin-5. Gene. 1989;79(2): 269-77.
22. Ueno H, Turnbull BB, Weissman IL. Two-step oligoclonal development of male germ cells. Proc Natl Acad Sci USA. 2009; 106(1): 175-80.
23. Ohinata Y, et al. Blimp1 is a critical determinant of the germ cell lineage in mice. Nature. 2005;436(7048): 207-13.
24. Zong H, et al. Mosaic analysis with double markers in mice. Cell. 2005;121(3): 479-92.
25. Livet J, et al. Transgenic strategies for combinatorial expression of fluorescent proteins in the nervous system. Nature. 2007;450 (7166): 56-62.
26. Red-Horse K, et al. Coronary arteries form by developmental reprogramming of venous cells. Nature. 2010;464(7288): 549-53.
27. Rinkevich Y, et al. Germ-layer and lineage-restricted stem/progenitors regenerate the mouse digit tip. Nature. 2011;476(7361): 409-13.
28. Zhang H, et al. Experimental evidence showing that no mitotically active female germline progenitors exist in postnatal mouse ovaries. Proc Natl Acad Sci USA. 2012;109(31): 12580-5.
29. Metzger D, et al. Conditional site-specific recombination in mammalian cells using a ligand-dependent chimeric Cre recombinase. Proc Natl Acad Sci USA. 1995;92(15): 6991-5.
30. Feil R, et al. Ligand-activated site-specific recombination in mice. Proc Natl Acad Sci USA. 1996;93(20): 10887-90.
31. Feil R, et al. Regulation of Cre recombinase activity by mutated estrogen receptor ligand-binding domains. Biochem Biophys Res Commun. 1997;237(3): 752-7.
32. Branda CS, Dymecki SM. Talking about a revolution: the impact of site-specific recombinases on genetic analyses in mice. Dev Cell. 2004;6(1): 7-28.
33. Soriano P. Generalized lacZ expression with the ROSA26 Cre reporter strain. Nat Genet. 1999;21(1): 70-1.
34. Bjerknes M, Cheng H. Intestinal epithelial stem cells and progenitors. Methods Enzymol. 2006;419: 337-83.
35. Li L, Clevers H. Coexistence of quiescent and active adult stem cells in mammals. Science. 2010;327(5965): 542-5.
36. Cheng H, Leblond CP. Origin, differentiation and renewal of the four main epithelial cell types in the mouse small intestine. I. Columnar cell. Am J Anat. 1974;141(4): 461-79.
37. Potten CS, Kovacs L, Hamilton E. Continuous labelling studies on mouse skin and intestine. Cell Tissue Kinet. 1974;7(3): 271-83.
38. Barker N, et al. Identification of stem cells in small intestine and colon by marker gene Lgr5. Nature. 2007;449(7165): 1003-7.
39. Sangiorgi E, Capecchi MR. Bmi1 is expressed in vivo in intestinal stem cells. Nat Genet. 2008;40(7): 915-20.
40. Itzkovitz S, et al. Single-molecule transcript counting of stem-cell markers in the mouse intestine. Nat Cell Biol. 2012;14(1): 106-14.
41. Tian H, et al. A reserve stem cell population in small intestine renders Lgr5-positive cells dispensable. Nature. 2011;478(7368): 255-9.
42. Schmidt GH, et al. Clonal analysis of intestinal crypt populations in mouse aggregation chimaeras. J Embryol Exp Morphol. 1985; 85: 121-30.
43. Schmidt GH, Winton DJ, Ponder BA. Development of the pattern of cell renewal in the crypt-villus unit of chimaeric mouse small intestine. Development. 1988;103(4): 785-90.
44. Snippert HJ, et al. Intestinal crypt homeostasis results from neutral competition between symmetrically dividing Lgr5 stem cells. Cell. 2010;143(1): 134-44.
45. Yan KS, et al. The intestinal stem cell markers Bmi1 and Lgr5 identify two functionally distinct populations. Proc Natl Acad Sci USA. 2012;109(2): 466-71.
46. Booth C, Potten CS. Gut instincts: thoughts on intestinal epithelial stem cells. J Clin Invest. 2000;105(11): 1493-9.
47. Cairnie AB, Millen BH. Fission of crypts in the small intestine of the irradiated mouse. Cell Tissue Kinet. 1975;8(2): 189-96.
48. Totafurno J, Bjerknes M, Cheng H. The crypt cycle. Crypt and villus production in the adult intestinal epithelium. Biophys J. 1987;52(2): 279-94.
49. Sato T, et al. Single Lgr5 stem cells build crypt-villus structures in vitro without a mesenchymal niche. Nature. 2009;459(7244): 262-5.
50. Klaus A, Birchmeier W. Wnt signalling and its impact on development and cancer. Nat Rev Cancer. 2008;8(5): 387-98.
51. Gregorieff A, et al. Expression pattern of Wnt signaling components in the adult intestine. Gastroenterology. 2005;129(2): 626-38.
52. Leppert M, et al. The gene for familial polyposis coli maps to the long arm of chromosome 5. Science. 1987;238(4832): 1411-3.
53. Kinzler KW, et al. Identification of FAP locus genes from chromosome 5q21. Science. 1991;253(5020): 661-5.
54. Nishisho I, et al. Mutations of chromosome 5q21 genes in FAP and colorectal cancer patients. Science. 1991;253(5020): 665-9.
55. Korinek V, et al. Constitutive transcriptional activation by a betacatenin- Tcf complex in APC-/- colon carcinoma. Science. 1997;275(5307): 1784-7.
56. Morin PJ, et al. Activation of beta-catenin-Tcf signaling in colon cancer by mutations in beta-catenin or APC. Science. 1997;275 (5307): 1787-90.
57. de Lau W, et al. Lgr5 homologues associate with Wnt receptors and mediate R-spondin signalling. Nature. 2011;476(7360): 293-7.
58. Binnerts ME, et al. R-Spondin1 regulates Wnt signaling by inhibiting internalization of LRP6. Proc Natl Acad Sci USA. 2007;104(37): 14700-5.
59. Kim KA, et al. R-Spondin family members regulate the Wnt pathway by a common mechanism. Mol Biol Cell. 2008;19(6): 2588-96.
60. Kim KA, et al. Mitogenic influence of human R-spondin1 on the intestinal epithelium. Science. 2005;309(5738): 1256-9.
61. Carmon KS, et al. R-spondins function as ligands of the orphan receptors LGR4 and LGR5 to regulate Wnt/beta-catenin signaling. Proc Natl Acad Sci USA. 2011;108(28): 11452-7.
62. Seshagiri S, et al. Recurrent R-spondin fusions in colon cancer. Nature. 2012; 448: 660-4.
63. Blasco MA. The epigenetic regulation of mammalian telomeres. Nat Rev Genet. 2007;8(4): 299-309.
64. Mosimann C, Hausmann G, Basler K. Beta-catenin hits chromatin: regulation of Wnt target gene activation. Nat Rev Mol Cell Biol. 2009;10(4): 276-86.
65. Park JI, et al. Telomerase modulates Wnt signalling by association with target gene chromatin. Nature. 2009;460(7251): 66-72.
66. Hoffmeyer K, et al. Wnt/beta-catenin signaling regulates telomerase in stem cells and cancer cells. Science. 2012;336(6088): 1549-54.
67. Greider CW. Molecular biology. Wnt regulates TERT-putting the horse before the cart. Science. 2012; 336(6088): 1519-20.
68. Fialkow PJ, Gartler SM, Yoshida A. Clonal origin of chronic myelocytic leukemia in man. Proc Natl Acad Sci USA. 1967;58(4): 1468-71.
69. Wiggans RG, et al. Probable clonal origin of acute myeloblastic leukemia following radiation and chemotherapy of colon cancer. Blood. 1978;52(4): 659-63.
70. Smith JW, Townsend DE, Sparkes RS. Genetic variants of glucose- 6-phosphate dehydrogenase in the study of carcinoma of the cervix. Cancer. 1971;28(2): 529-32.
71. Linder D, Gartler SM. Glucose-6-phosphate dehydrogenase mosaicism: utilization as a cell marker in the study of leiomyomas. Science. 1965;150(3692): 67-9.
72. Ponder BA, Wilkinson MM. Direct examination of the clonality of carcinogen-induced colonic epithelial dysplasia in chimeric mice. J Natl Cancer Inst. 1986;77(4): 967-76.
73. Griffiths DF, et al. The clonal origin of experimental large bowel tumours. Br J Cancer. 1989;59(3): 385-7.
74. Friedman JM, et al. Probable clonal origin of neurofibrosarcoma in a patient with hereditary neurofibromatosis. J Natl Cancer Inst. 1982;69(6): 1289-92.
75. Hsu SH, et al. Multiclonal origin of polyps in Gardner syndrome. Science. 1983;221(4614): 951-3.
76. Fearon ER, Hamilton SR, Vogelstein B. Clonal analysis of human colorectal tumors. Science. 1987;238(4824): 193-7.
77. Novelli MR, et al. Polyclonal origin of colonic adenomas in an XO/XY patient with FAP. Science. 1996;272(5265): 1187-90.