Germ-layer and lineage-restricted stem/progenitors regenerate the mouse digit tip

Nature

Volumn 476, Issue 7361, 2011, Pages 409-414

  Rinkevich, Yuval ^a   Lindau, Paul ^a   Ueno, Hiroo ^a   Longaker, Michael T ^a   Weissman, Irving L ^a,b  

^a STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b STANFORD UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYAN FLUORESCENT PROTEIN;

AMPHIBIAN; CYTOLOGY; EVOLUTIONARY BIOLOGY; FISH; GENE EXPRESSION; LIMB; PHYSIOLOGICAL RESPONSE; PROTEIN; REGROWTH; RODENT;

ALLOGENEIC HEMATOPOIETIC STEM CELL TRANSPLANTATION; ANGIOGENESIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BLASTEMA; CELL CLONE; CELL FATE; CELL GROWTH; CELL REGENERATION; CONTROLLED STUDY; EMBRYO; FINGER; GENE MAPPING; GERM CELL; GERM LAYER; LIMB AMPUTATION; LIMB REGENERATION; MOUSE; NONHUMAN; PARABIOSIS; PLURIPOTENT STEM CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; STEM CELL; VERTEBRATE;

ANIMALS; BONE AND BONES; CELL LINEAGE; CLONE CELLS; ECTODERM; ENDOTHELIUM; EXTREMITIES; FEMALE; GERM LAYERS; HEMATOPOIETIC STEM CELLS; MALE; MESODERM; MICE; ORGAN SPECIFICITY; REGENERATION; STEM CELLS; TENDONS;

AMPHIBIA; MUS; VERTEBRATA;

EID: 80052056733     PISSN: 00280836     EISSN: 14764687     Source Type: Journal    
DOI: 10.1038/nature10346     Document Type: Article

References (46)

1. Rinkevich,B.,Shlemberg,Z.&Fishelson, L.Whole-body protochordate regeneration from totipotent blood cells. Proc. Natl Acad. Sci. USA 92, 7695-7699 (1995).
2. Rinkevich, Y., Paz, G., Rinkevich, B. & Reshef, R. Systemic bud induction and retinoic acid signaling underlie whole body regeneration in the urochordate Botrylloides leachi. PLoS Biol. 5, e71 (2007).
3. Voskoboynik, A. et al. Striving for normality: whole body regeneration through a series of abnormal generations. FASEB J. 21, 1335-1344 (2007). (Pubitemid 46684836)
4. Sánchez Alvarado, A. Regeneration in the metazoans: why does it happen? Bioessays 22, 578-590 (2000). (Pubitemid 30387979)
5. Han, M., Yang, X., Lee, J., Allan, C. H. & Muneoka, K. Development and regeneration of the neonatal digit tip in mice. Dev. Biol. 315, 125-135 (2008).
6. Schotte, O. E. & Smith, C. B. Wound healing processes in amputated mouse digits. Biol. Bull. 117, 546-561 (1959).
7. Borgens, R. B. Mice regrowthe tips of their foretoes. Science217,747-750(1982). (Pubitemid 12049580)
8. Reginelli, A. D., Wang, Y. Q., Sassoon, D. & Muneoka, K. Digit tip regeneration correlates with regions of Msx1 (Hox 7) expression in fetal and newborn mice. Development 121, 1065-1076 (1995).
9. Neufeld, D. A. & Zhao, W. Phalangeal regrowth in rodents: postamputational bone regrowth depends upon the level of amputation. Prog. Clin. Biol. Res. 383A, 243-252 (1993).
10. Illingworth, C. M. Trapped fingers and amputated fingertips in children. J. Pediatr. Surg. 9, 853-858 (1974).
11. Rosenthal, L. J., Reiner, M. A. & Bleicher, M. A. Nonoperative management of distal fingertip amputations in children. Pediatrics 64, 1-3 (1979). (Pubitemid 9182692)
12. Vidal, P. & Dickson, M. G. Regeneration of the distal phalanx. A case report. J. Hand Surg. 18, 230-233 (1993). (Pubitemid 23119139)
13. Morgan, T. H. Regeneration (Macmillan, 1901).
14. Bratincsák, A. et al. CD45-positive blood cells give rise to uterine epithelial cells in mice. Stem Cells 25, 2820-2826 (2007). (Pubitemid 350127866)
15. Faustman, D. L. et al.Comment on papers byChong et al.Nishioet al., andSuri et al. on diabetes reversal in NOD mice. Science 314, 1243a, doi:10.1126/science.1129811 (2006).
16. Djouad, F., Bouffi, C., Ghannam, S., Noël, D. & Jorgensen, C. Mesenchymal stem cells: innovative therapeutic tools for rheumatic diseases.NatureRev.Rheumatol 5, 392-399 (2009).
17. Zaidi, N. & Nixon, A. J. Stemcell therapy in bone repair and regeneration. Ann. NY Acad. Sci. 1117, 62-72 (2007). (Pubitemid 350191290)
18. Brockes, J. P. & Kumar, A. Appendage regeneration in adult vertebrates and implications for regenerative medicine. Science 310, 1919-1923 (2005). (Pubitemid 43005978)
19. Tamura, K., Ohgo, S. & Yokoyama, H. Limb blastema cell: a stem cell for morphological regeneration. Dev. Growth Differ. 52, 89-99 (2010).
20. Christen, B., Robles, V., Raya, M., Paramonov, I.& Belmonte, J. C. Regeneration and reprogramming compared. BMC Biol. 8, 5 (2010).
21. Tsonis, P. A. Stem cells and blastema cells. Curr. Stem Cell Res. Ther. 3, 53-54 (2008).
22. Weissman, I. L. Stemcells: units of development, units of regeneration, and units in evolution. Cell 100, 157-168 (2000). (Pubitemid 30046304)
23. Wagers, A. J., Sherwood, R. I., Christensen, J. L. & Weissman, I. L. Little evidence for developmental plasticity of adult hematopoietic stem cells. Science 297, 2256-2259 (2002).
24. Wagers, A. J. & Weissman, I. L. Plasticity of adult stem cells. Cell 116, 639-648 (2004). (Pubitemid 38326723)
25. Purhonen, S. J. et al. Bone marrow-derived circulating endothelial precursors do not contribute to vascular endotheliumandare not needed for tumor growth. Proc. Natl Acad. Sci. USA 105, 6620-6625 (2008).
26. Hamrick, M. W. Development and evolution of the mammalian limb: adaptive diversification of nails, hooves, and claws. Evol. Dev. 3, 355-363 (2001). (Pubitemid 32984019)
27. Said, S., Parke, W. & Neufeld, D. A. Vascular supplies differ in regenerating and nonregenerating amputated rodent digits. Anat. Rec. A 278, 443-449 (2004). (Pubitemid 38619656)
28. Vasioukhin, V., Degenstein, L., Wise, B. & Fuchs, E. The magical touch: genome targeting in epidermal stemcells induced by tamoxifen application tomouse skin. Proc. Natl Acad. Sci. USA 96, 8551-8556 (1999). (Pubitemid 29354829)
29. Muzumdar, M. D., Tasic, B., Miyamichi, K., Li, L. & Luo, L. A global doublefluorescent Cre reporter mouse. Genesis 45, 593-605 (2007). (Pubitemid 350013057)
30. Indra,A.K. et al. Temporally-controlledsite-specificmutagenesis inthe basal layer of the epidermis: comparison of the recombinase activity of the tamoxifen-inducible Cre-ERT and Cre-ERT2 recombinases. Nucleic Acids Res. 27, 4324-4327 (1999).
31. Kimmel, R. A. et al. Two lineage boundaries coordinate vertebrate apical ectodermal ridge formation. Genes Dev. 14, 1377-1389 (2000). (Pubitemid 30397081)
32. Logan, M. et al. Expression of Cre recombinase in the developing mouse limb bud driven by a Prxl enhancer. Genesis 33, 77-80 (2002). (Pubitemid 34651279)
33. Akiyama, H. et al. Osteo-chondroprogenitor cells are derived fromSox9 expressing precursors. Proc. Natl Acad. Sci. USA 102, 14665-14670 (2005). (Pubitemid 41457113)
34. Nowak, J. A., Polak, L., Pasolli, H. A. & Fuchs, E. Hair follicle stem cells are specified and function in early skin morphogenesis. Cell Stem Cell 3, 33-43 (2008).
35. Pryce, B. A., Brent, A. E., Murchison, N. D., Tabin, C. J.& Schweitzer, R. Generation of transgenic tendon reporters, ScxGFP and ScxAP, using regulatory elements of the scleraxis gene. Dev. Dyn. 236, 1677-1682 (2007). (Pubitemid 46932370)
36. Forde, A., Constien, R., Gröne, H. J., Hämmerling, G. & Arnold, B. Temporal Cremediated recombination exclusively in endothelial cells using Tie2 regulatory elements. Genesis 33, 191-197 (2002). (Pubitemid 34966841)
37. Monvoisin, A. et al. VE-cadherin-CreERT2 transgenicmouse: amodel for inducible recombination in the endothelium. Dev. Dyn. 235, 3413-3422 (2006). (Pubitemid 44888207)
38. Fernando, W. A. et al. Wound healing and blastemaformation in regenerating digit tips of adult mice. Dev. Biol. 350, 301-310 (2011).
39. Forsberg, E. C., Bhattacharya, D. & Weissman, I. L. Hematopoietic stem cells: expression profiling and beyond. Stem Cell Rev. 2, 23-30 (2006). (Pubitemid 44195975)
40. Wright, D. E., Wagers, A. J., Gulati, A. P., Johnson, F. L.&Weissman, I. L. Physiological migration of hematopoietic stem and progenitor cells. Science 294, 1933-1936 (2001). (Pubitemid 33101591)
41. Liversage, R. A. in A History of Regeneration Research: Milestones in the Evolution of a Science (eds Dinsmore, C. E.) (Cambridge Univ. Press, 1991).
42. Ito, M. et al. Wnt-dependent de novo hair follicle regeneration in adult mouse skin after wounding. Nature 447, 316-320 (2007). (Pubitemid 46788832)
43. Chan, C. K. et al. Endochondral ossification is required for haematopoietic stemcell niche formation. Nature 457, 490-494 (2009).
44. Gargioli, C. & Slack, J. M. Cell lineage tracing during Xenopus tail regeneration. Development 131, 2669-2679 (2004). (Pubitemid 38877899)
45. Kragl, M. et al. Cells keep a memory of their tissue origin during axolotl limb regeneration. Nature 460, 60-65 (2009).
46. Tu, S.&Johnson, S. L. Fate restrictionin the growingand regeneratingzebrafish fin. Dev. Cell 20, 725-732 (2011).