A novel MDCKII in vitro model for assessing ABCG2-drug interactions and regulation of ABCG2 transport activity in the caprine mammary gland by environmental pollutants and pesticides

Toxicology in Vitro

Volumn 28, Issue 3, 2014, Pages 432-441

  Halwachs, Sandra ^a   Wassermann, Louise ^a   Honscha, Walther ^a  

^a UNIVERSITY OF LEIPZIG   (Germany)

Author keywords

Aryl hydrocarbon receptor (AhR); Caprine ABCG2; Dioxin; Mammary gland; MDCKII cells; Pesticides

Indexed keywords

2,3,7,8 TETRACHLORODIBENZO PARA DIOXIN; AROCLOR 1254; AROMATIC HYDROCARBON RECEPTOR; BREAST CANCER RESISTANCE PROTEIN; ENZYME INHIBITOR; ETHOXYRESORUFIN DEETHYLASE; IPRODIONE; MONEPANTEL; PESTICIDE; PROCHLORAZ;

ANIMAL CELL; ARTICLE; CAPRINE MODEL; ENZYME ACTIVITY; IN VITRO STUDY; MAMMARY GLAND; MDCK CELL; NONHUMAN; POLLUTANT; PROTEIN EXPRESSION; PROTEIN INDUCTION; PROTEIN SECRETION; PROTEIN STABILITY; PROTEIN TRANSPORT; REGULATORY MECHANISM;

ARYL HYDROCARBON RECEPTOR (AHR); CAPRINE ABCG2; DIOXIN; MAMMARY GLAND; MDCKII CELLS; PESTICIDES;

ANIMALS; ATP-BINDING CASSETTE TRANSPORTERS; BIOLOGICAL TRANSPORT; CYTOCHROME P-450 CYP1A1; DOGS; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG INTERACTIONS; ENVIRONMENTAL POLLUTANTS; FEMALE; GENE EXPRESSION REGULATION; GOATS; MADIN DARBY CANINE KIDNEY CELLS; MAMMARY GLANDS, ANIMAL; MODELS, BIOLOGICAL; PESTICIDES; TIME FACTORS;

EID: 84892867956     PISSN: 08872333     EISSN: 18793177     Source Type: Journal    
DOI: 10.1016/j.tiv.2013.12.015     Document Type: Article

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