Determination of functional ABCG2 activity and assessment of drug-ABCG2 interactions in dairy animals using a novel MDCKII in vitro model

Journal of Pharmaceutical Sciences

Volumn 102, Issue 2, 2013, Pages 772-784

  Wassermann, Louise ^a   Halwachs, Sandra ^a   Lindner, Stefan ^a   Honscha, Kerstin U ^a   Honscha, Walther ^a  

^a UNIVERSITY OF LEIPZIG   (Germany)

Author keywords

ABCG2 BCRP; Active transport; Drug residues; Efflux pumps; Hoechst H33342; in vitro models; Mammary gland; Mammary transport secretion; MDCKII cells; Membrane transport transporters

Indexed keywords

ALBENDAZOLE; CEFALEXIN; COMPLEMENTARY DNA; ENROFLOXACIN; EQUOL; QUERCETIN; XENOBIOTIC AGENT;

ANIMAL CELL; ARTICLE; BREAST CANCER RESISTANCE GENE; CELL CULTURE; CONTROLLED STUDY; COW; GENE AMPLIFICATION; GENE CONSTRUCT; GOAT; IN VITRO STUDY; LACTATION; MAMMARY GLAND; MILK; MOLECULAR CLONING; NONHUMAN; ONCOGENE; POLYMERASE CHAIN REACTION; SHEEP;

EID: 84872498978     PISSN: 00223549     EISSN: 15206017     Source Type: Journal    
DOI: 10.1002/jps.23399     Document Type: Article

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